Clinical use of [TIMP-2]•[IGFBP7] biomarker testing to assess risk of acute kidney injury in critical care: guidance from an expert panel.

abstract：:The pathogenesis of sepsis-induced multiple organ failure may crucially depend on the development of mitochondrial dysfunction and consequent cellular energetic failure. According to this hypothesis, interventions aimed at preventing or reversing mitochondrial damage may have major clinical relevance, although the tim...

journal_title：Critical care (London, England)

authors： Protti A,Singer M

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Survivors of an acute critical illness with continuing organ dysfunction and uncontrolled inflammatory responses are prone to become chronically critically ill. As mental sequelae, a post-traumatic stress disorder and an associated decrease in the health-related quality of life (QoL) may occur, not only in t...

journal_title：Critical care (London, England)

authors： Wintermann GB,Petrowski K,Weidner K,Strauß B,Rosendahl J

更新日期：2019-02-08 00:00:00

abstract：:Organ donation offers opportunities for people in critical care units to help save the lives of other patients. It is not always easy, however, to handle the transition from treating a patient to preserving a potential donor, and organ donation consistently provokes ethical questions in critical care units. What do we...

journal_title：Critical care (London, England)

authors： Hoeyer K,Jensen AM

更新日期：2011-01-24 00:00:00

abstract：BACKGROUND:In critical care units, pupil examination is an important clinical parameter for patient monitoring. Current practice is to use a penlight to observe the pupillary light reflex. The result seems to be a subjective measurement, with low precision and reproducibility. Several quantitative pupillometer devices ...

journal_title：Critical care (London, England)

authors： Couret D,Boumaza D,Grisotto C,Triglia T,Pellegrini L,Ocquidant P,Bruder NJ,Velly LJ

更新日期：2016-03-13 00:00:00

abstract：INTRODUCTION:This study aimed to examine the long-term outcome for patients with end-stage renal failure (ESRF) who survived multiple-organ failure. METHODS:We performed a review of databases from the renal medicine service and intensive care units (ICU) of the participating hospitals within Imperial College Healthcar...

journal_title：Critical care (London, England)

authors： Chapman RJ,Templeton M,Ashworth S,Broomhead R,McLean A,Brett SJ

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the global spread of coronavirus disease (COVID-19). Our understanding of the impact this virus has on the nervous system is limited. Our review aims to inform and improve decision-making among the physicians treating COVID-19 ...

journal_title：Critical care (London, England)

authors： Nepal G,Rehrig JH,Shrestha GS,Shing YK,Yadav JK,Ojha R,Pokhrel G,Tu ZL,Huang DY

更新日期：2020-07-13 00:00:00

abstract：OBJECTIVES:We sought to study the association between sedation status, medications (benzodiazepines, opioids, and antipsychotics), and clinical outcomes in a resource-limited setting. DESIGN:A longitudinal study of critically ill participants on mechanical ventilation. SETTING:Five intensive care units (ICUs) in four...

journal_title：Critical care (London, England)

authors： Aragón RE,Proaño A,Mongilardi N,de Ferrari A,Herrera P,Roldan R,Paz E,Jaymez AA,Chirinos E,Portugal J,Quispe R,Brower RG,Checkley W

更新日期：2019-04-17 00:00:00

abstract：:Several papers are discussed including the CARP (Coronary Artery Revascularisation Prophylaxis) trial, examining the role, if any, of preoperative coronary revascularisation and a study examining the heart rate in the intensive care unit (ICU) population. We also take a look at infections in the ICU with particular re...

journal_title：Critical care (London, England)

authors： Tomlinson LA,Forni LG

更新日期：2005-04-01 00:00:00

abstract：:Many prior studies have shown that, in critically ill patients, acute kidney injury (AKI) commonly occurs in association with sepsis and its presence portends an increased likelihood of poor outcomes. In contrast, few studies have focused specifically on the influence of AKI on the long-term risk of developing sepsis....

journal_title：Critical care (London, England)

authors： Clark E,Bagshaw SM

更新日期：2014-01-24 00:00:00

abstract：BACKGROUND:The aim of this study, conducted in 2006, was to find out whether changes in sedation management in German intensive care units took place in comparison with our survey from 2002. METHODS:We conducted a follow-up survey with a descriptive and comparative cross-sectional multi-center design. A postal survey ...

journal_title：Critical care (London, England)

authors： Martin J,Franck M,Sigel S,Weiss M,Spies C

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Acute-on-chronic liver failure (ACLF) is characterized by the presence of acute decompensation (AD) of cirrhosis, organ failure, and high short-term mortality rates. Hemodynamic dysfunction and activation of endogenous vasoconstrictor systems are thought to contribute to the pathogenesis of ACLF. We explored...

journal_title：Critical care (London, England)

authors： Kerbert AJC,Verspaget HW,Navarro ÀA,Jalan R,Solà E,Benten D,Durand F,Ginès P,van der Reijden JJ,van Hoek B,Coenraad MJ,CANONIC Study Investigators of the EASL-CLIF Consortium.

更新日期：2017-12-21 00:00:00

abstract：BACKGROUND:Endothelial hyperpermeability following cardiopulmonary bypass (CPB) contributes to microcirculatory perfusion disturbances and postoperative complications after cardiac surgery. We investigated the postoperative course of renal and pulmonary endothelial barrier function and the association with microcircula...

journal_title：Critical care (London, England)

authors： Dekker NAM,van Leeuwen ALI,van Strien WWJ,Majolée J,Szulcek R,Vonk ABA,Hordijk PL,Boer C,van den Brom CE

更新日期：2019-04-11 00:00:00

abstract：:Critical care medicine in China has made great advances in recent decades. This has led to an unavoidable issue: end-of-life ethics. With advances in medical technology and therapeutics allowing the seemingly limitless maintenance of life, the exact time of death of an individual patient is often determined by the dec...

journal_title：Critical care (London, England)

authors： Li LB

更新日期：2013-12-04 00:00:00

abstract：INTRODUCTION:Prompt diagnosis of candidaemia and invasive candidosis is crucial to the early initiation of antifungal therapy. The poor sensitivity of blood cultures (BCs) has led to the development of fungal glycan tests as a diagnostic adjunct. We analysed the performance of tests for the detection of circulating β-D...

journal_title：Critical care (London, England)

authors： Poissy J,Sendid B,Damiens S,Ichi Ishibashi K,François N,Kauv M,Favory R,Mathieu D,Poulain D

更新日期：2014-06-29 00:00:00

abstract：INTRODUCTION:Between 1 and 31% of patients suffering out-of-hospital cardiac arrest (OHCA) survive to discharge from hospital. International studies have shown that the level of care provided by the admitting hospital determines survival for patients suffering from OHCA. These data may only be partially transferable to...

journal_title：Critical care (London, England)

authors： Wnent J,Seewald S,Heringlake M,Lemke H,Brauer K,Lefering R,Fischer M,Jantzen T,Bein B,Messelken M,Gräsner JT

更新日期：2012-09-12 00:00:00

abstract：INTRODUCTION:The present study examined the median survival, life expectancies, and cumulative incidence rate (CIR) of patients undergoing prolonged mechanical ventilation (PMV) stratified by different underlying diseases. METHODS:According to the National Health Insurance Research Database of Taiwan, there were 8,906...

journal_title：Critical care (London, England)

authors： Hung MC,Lu HM,Chen L,Hu FC,Chan SY,Yan YH,Fan PS,Lin MS,Chen CR,Kuo LC,Yu CJ,Wang JD

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:It has been unclear if mechanical cardiopulmonary resuscitation (CPR) is a viable alternative to manual CPR. We aimed to compare resuscitation outcomes before and after switching from manual CPR to load-distributing band (LDB) CPR in a multi-center emergency department (ED) trial. METHODS:We conducted a p...

journal_title：Critical care (London, England)

authors： Hock Ong ME,Fook-Chong S,Annathurai A,Ang SH,Tiah L,Yong KL,Koh ZX,Yap S,Sultana P

更新日期：2012-08-03 00:00:00

abstract：INTRODUCTION:Glutamine supplementation has beneficial effects on morbidity and mortality in critically ill patients, possibly in part through an attenuation of the proinflammatory cytokine response and a stimulation of heat shock protein (HSP)70. We infused either alanine-glutamine or saline during endotoxin challenge ...

journal_title：Critical care (London, England)

authors： Andreasen AS,Pedersen-Skovsgaard T,Mortensen OH,van Hall G,Moseley PL,Pedersen BK

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Although effective strategies are available for the management of chronic hypertension, less is known about treating patients with acute, severe elevations in blood pressure. Using data from the European registry for Studying the Treatment of Acute hyperTension (Euro-STAT), we sought to evaluate 'real-life...

journal_title：Critical care (London, England)

authors： Vuylsteke A,Vincent JL,de La Garanderie DP,Anderson FA,Emery L,Wyman A,Rushton-Smith S,Gore JM,Euro-STAT Investigators.

更新日期：2011-01-01 00:00:00

abstract：:Impairment of the protein C pathway plays a central role in the pathogenesis of sepsis. Administration of recombinant human activated protein C (rhAPC) may correct the dysregulated anticoagulant mechanism and prevent propagation of thrombin generation and formation of microvascular thrombosis. Furthermore, it may simu...

journal_title：Critical care (London, England)

authors： Levi M,van der Poll T

更新日期：2007-01-01 00:00:00

abstract：:This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency medicine 2017. Other selected articles can be found online at http://ccforum.com/series/annualupdate2017 . Further information about the Annual Update in Intensive Care and Emergency Medicine is available from http://www...

journal_title：Critical care (London, England)

authors： Tagami T,Yasunaga H,Yokota H

更新日期：2017-03-21 00:00:00

abstract：BACKGROUND:Renal perfusion status remains poorly studied at the bedside during septic shock. We sought to measure cortical renal perfusion in patients with septic shock during their first 3 days of care using renal contrast enhanced ultrasound (CEUS). METHODS:We prospectively included 20 ICU patients with septic shock...

journal_title：Critical care (London, England)

authors： Harrois A,Grillot N,Figueiredo S,Duranteau J

更新日期：2018-06-15 00:00:00

abstract：BACKGROUND:Our objective was to evaluate the impact of gastric versus post-pyloric feeding on the incidence of pneumonia, caloric intake, intensive care unit (ICU) length of stay (LOS), and mortality in critically ill and injured ICU patients. METHOD:Data sources were Medline, Embase, Healthstar, citation review of re...

journal_title：Critical care (London, England)

authors： Marik PE,Zaloga GP

更新日期：2003-06-01 00:00:00

abstract：:Novel insights into the metabolic alterations of critical illness were published in Critical Care in 2009. The association between early hypoglycaemia/high glycemic variability and poor outcome was confirmed. Improvements in the understanding of the pathophysiological mechanisms of stress hyperglycemia and potential p...

journal_title：Critical care (London, England)

authors： Huberlant V,Preiser JC

更新日期：2010-01-01 00:00:00

abstract：:Sepsis is characterized by a dysregulated immune response to infection leading to life-threatening organ dysfunction. Sepsis-induced liver injury is recognized as a powerful independent predictor of mortality in the intensive care unit. During systemic infections, the liver regulates immune defenses via bacterial clea...

journal_title：Critical care (London, England)

authors： Sun J,Zhang J,Wang X,Ji F,Ronco C,Tian J,Yin Y

更新日期：2020-10-19 00:00:00

abstract：BACKGROUND:Acute respiratory failure (ARF) remains a common hazardous complication in immunocompromised patients and is associated with increased mortality rates when endotracheal intubation is needed. We aimed to evaluate the effect of early noninvasive ventilation (NIV) compared with oxygen therapy alone in this pati...

journal_title：Critical care (London, England)

authors： Huang HB,Xu B,Liu GY,Lin JD,Du B

更新日期：2017-01-07 00:00:00

abstract：INTRODUCTION:Data on the epidemiology and management of anorexia nervosa (AN) in the intensive care unit (ICU) are scarce. The aim of this study was to evaluate the prevalence and associated morbidity and mortality of AN in French ICUs. METHODS:We randomly selected 30 ICUs throughout France. Thereafter, we retrospecti...

journal_title：Critical care (London, England)

authors： Vignaud M,Constantin JM,Ruivard M,Villemeyre-Plane M,Futier E,Bazin JE,Annane D,AZUREA group (AnorexieRea Study Group).

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:Delivery of bronchodilators with a metered-dose inhaler (MDI) and a spacer device in mechanically ventilated patients has become a widespread practice. However, except for the short-acting beta2-agonist salbutamol, the duration of action of other bronchodilators, including long-acting beta2-agonists, deliv...

journal_title：Critical care (London, England)

authors： Malliotakis P,Linardakis M,Gavriilidis G,Georgopoulos D

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:An increasing body of evidence from laboratory and clinical studies suggests that vasopressin may represent a promising alternative vasopressor for use during cardiac arrest and resuscitation. Current guidelines for cardiopulmonary resuscitation recommend the use of adrenaline (epinephrine), with vasopress...

journal_title：Critical care (London, England)

authors： Grmec S,Mally S

更新日期：2006-02-01 00:00:00

abstract：:Many advances in medicine have been achieved through challenging established dogma with revolutionary thought and novel practices. Each and every specialty is reinvigorated by regular re-evaluation of processes and practices in the light of new evidence and fresh conceptualization. Challenge can galvanize fresh thinki...

journal_title：Critical care (London, England)

authors： Singer M,Matthay MA

更新日期：2011-07-26 00:00:00