The International Sepsis Forum's controversies in sepsis: corticosteroids should be used to treat septic shock.

Abstract:

:The use of corticosteroids in septic shock remains controversial. It has been demonstrated that high doses of steroids (30 mg/kg methylprednisolone) for short periods of time are not beneficial. More recent studies using smaller doses (200-300 mg/day hydrocortisone) for longer periods of time have shown beneficial effects. These positive effects have included reversal of shock, trends toward decreased organ system dysfunction and decreased mortality. Based on the high proportion of patients who have relative adrenal insufficiency, the benefits of low doses of steroids and the minimal risks, steroids should be used to treat septic shock.

journal_name

Crit Care

authors

Goodman S,Sprung CL,International Sepsis Forum.

doi

10.1186/cc1537

keywords:

subject

Has Abstract

pub_date

2002-10-01 00:00:00

pages

381-3

issue

5

eissn

1364-8535

issn

1466-609X

journal_volume

6

pub_type

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