Abstract:
BACKGROUND:Several studies have shown that cocoa and cocoa-containing foods have the potential to lower blood pressure and improve endothelial function. Most of the studies reporting the beneficial effects of dark chocolate on blood pressure have been short (≤ 4 weeks). The aim of the present 8-wks (weeks) study was to assess the effects of regular consumption of dark chocolate during a reduced snack consumption intervention on blood pressure and other cardiovascular risk factors in mildly hypertensive individuals. DESIGN:This was a randomized, controlled, cross-over trial involving 22 adults (8 women, 14 men), aged 33-64 y, BMI 27.7 ± 3.7 kg/m(2) with mild hypertension. During the intervention period (8-wks) the participants reduced the intake of habitual snacks and replaced them with dark chocolate (49 g/day). In the control period, they only reduced the snacks without any added chocolate. Data (blood lipid profile, glucose, insulin, 24 h blood pressure) was collected in the beginning and end of both periods (intervention and control), and some variables also in the run-in and run-out periods (weight, body fat percentage, blood pressure, arterial stiffness index, diet and physical activity). RESULTS:Daily consumption of dark chocolate had no effects on 24 h blood pressure, resting blood pressure (mean ± SD, pre 142 ± 11.5/89 ± 8.4 mmHg vs. post 142 ± 14.2/88 ± 9.4 mmHg in systolic and diastolic blood pressure, respectively) or arterial stiffness (mean ± SD, pre 7.68 ± 0.88 vs. post 7.76 ± 0.89). Weight was reduced by 1.0 ± 2.2 kg during the control (reduced snack only) period, but was unchanged while eating chocolate (p < 0.027 between the treatments). CONCLUSION:The data collected in this study indicates that inclusion of dark chocolate daily in the diet had no significant effects on blood pressure or other cardiovascular risk factors during a reduced snack period. TRIAL REGISTRATION:ClinicalTrials.gov identifier NCT02130141.
journal_name
Nutr Jjournal_title
Nutrition journalauthors
Koli R,Köhler K,Tonteri E,Peltonen J,Tikkanen H,Fogelholm Mdoi
10.1186/s12937-015-0075-3subject
Has Abstractpub_date
2015-08-22 00:00:00pages
84issn
1475-2891pii
10.1186/s12937-015-0075-3journal_volume
14pub_type
杂志文章,随机对照试验abstract:BACKGROUND:Psychosocial stress leads to altered neuroendocrine functions, such as serotonergic dysfunction, as well as alterations of the autonomic nervous system and the hypothalamic-pituitary-adrenal (HPA)-axis activity resulting in an imbalance between inhibitory and excitatory neurotransmitters. Poor dietary intake...
journal_title:Nutrition journal
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12937-015-0030-3
更新日期:2015-05-06 00:00:00
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journal_title:Nutrition journal
pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:Nutrition journal
pub_type: 临床试验,杂志文章,随机对照试验
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pub_type: 杂志文章
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journal_title:Nutrition journal
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Nutrition journal
pub_type: 临床试验,杂志文章
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journal_title:Nutrition journal
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pub_type: 杂志文章
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journal_title:Nutrition journal
pub_type: 杂志文章
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journal_title:Nutrition journal
pub_type: 杂志文章,随机对照试验
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更新日期:2018-11-30 00:00:00
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journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/s12937-015-0116-y
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journal_title:Nutrition journal
pub_type: 杂志文章,评审
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pub_type: 杂志文章
doi:10.1186/1475-2891-6-24
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更新日期:2010-12-22 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2012-10-15 00:00:00
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pub_type: 杂志文章
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更新日期:2020-06-20 00:00:00
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journal_title:Nutrition journal
pub_type: 杂志文章,随机对照试验
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更新日期:2011-10-20 00:00:00
abstract:BACKGROUND:There is substantial evidence that low consumption of fruit and vegetables (FV) is a major risk factor for many chronic diseases. The aim of this study was to assess FV consumption and the variables that influence it among elderly individuals in Iran aged 60 and over. METHODS:This was a cross-sectional stud...
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pub_type: 杂志文章
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更新日期:2010-01-13 00:00:00
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journal_title:Nutrition journal
pub_type: 杂志文章,随机对照试验
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更新日期:2010-05-21 00:00:00
abstract:BACKGROUND:The plant stanol ester margarine Benecol is a functional food that has been shown to lower effectively serum total and LDL-cholesterol. The purpose of this post-marketing study is to characterize users of plant stanol ester margarine with and without cardiovascular disease. METHODS:A cohort of plant stanol ...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/1475-2891-4-20
更新日期:2005-06-01 00:00:00
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journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/s12937-018-0417-z
更新日期:2018-11-19 00:00:00