Abstract:
BACKGROUND:Measuring the effects of the acute intake of natural products on human biomarker concentrations, such as those related to oxidation and inflammation, can be an advantageous strategy for early clinical research on an ingredient or product. METHODS:31 total healthy subjects were randomized in a double-blinded, placebo-controlled, acute pilot study with post-hoc subgroup analysis on 20 of the subjects. The study examined the effects of a single dose of a polyphenol-rich beverage (PRB), commercially marketed as "SoZo(®)", on serum anti-inflammatory and antioxidant markers. In addition, phytochemical analyses of PRB, and in vitro antioxidant capacity were also performed. RESULTS:At 1 hour post-intake, serum values for 8-iso-PGF2-alpha and advanced oxidation protein products decreased significantly by 40% and 39%, respectively. Additionally, there was a trend toward decreased C-reactive protein, and increased nitric oxide levels. Both placebo and PRB treatment resulted in statistically significant increases in hydroxyl radical antioxidant capacity (HORAC) compared to baseline; PRB showed a higher percent change (55-75% versus 23-74% in placebo group), but the two groups did not differ significantly from each other. CONCLUSIONS:PRB produced statistically significant changes in several blood biomarkers related to antioxidant/anti-inflammatory effects. Future studies are justified to verify results and test for cumulative effects of repeated intakes of PRB. The study demonstrates the potential utility of acute biomarker measurements for evaluating antioxidant/anti-inflammatory effects of natural products.
journal_name
Nutr Jjournal_title
Nutrition journalauthors
Nemzer BV,Rodriguez LC,Hammond L,Disilvestro R,Hunter JM,Pietrzkowski Zdoi
10.1186/1475-2891-10-67subject
Has Abstractpub_date
2011-06-15 00:00:00pages
67issn
1475-2891pii
1475-2891-10-67journal_volume
10pub_type
杂志文章,随机对照试验abstract:BACKGROUND:Few localized food frequency questionnaires (FFQ) have been developed and used in Chinese nutrition surveys despite China's large population and diverse dietary habits. METHOD:We analyzed data collected in two waves (six months apart) of the Shanghai Diet and Health Study in 2012-2013, from 1623 Shanghai re...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/s12937-019-0454-2
更新日期:2019-05-23 00:00:00
abstract:BACKGROUND:Based on data obtained from pregnant women who participated in the Mothers and Children's Environmental Health (MOCEH) study in South Korea, we aimed to determine whether maternal intake of fruits and vegetables or vitamin C is associated with fetal and infant growth. METHODS:A total of 1138 Korean pregnant...
journal_title:Nutrition journal
pub_type: 杂志文章,多中心研究
doi:10.1186/s12937-018-0410-6
更新日期:2018-11-12 00:00:00
abstract:BACKGROUND:Parents who perceive common infant behaviors as formula intolerance-related often switch formulas without consulting a health professional. Up to one-half of formula-fed infants experience a formula change during the first six months of life. METHODS:The objective of this study was to assess discontinuance ...
journal_title:Nutrition journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1186/1475-2891-8-27
更新日期:2009-06-19 00:00:00
abstract:INTRODUCTION:Cinnamon is currently marketed as a remedy for obesity, glucose intolerance, diabetes mellitus and dyslipidaemia. Integrative medicine is a new concept that combines conventional treatment with evidence-based complementary therapies. AIM:The aim of this review is to critically evaluate the experimental ev...
journal_title:Nutrition journal
pub_type: 杂志文章,评审
doi:10.1186/s12937-015-0098-9
更新日期:2015-10-16 00:00:00
abstract:BACKGROUND:Inadequate protein intake is known to be deleterious in animals. Using WHO consensus documents for human nutrient requirements, the protein:energy ratio (P:E) of an adequate diet is > 5%. Cassava has a very low protein content. This study tested the hypothesis that Nigerian and Kenyan children consuming cass...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/1475-2891-9-9
更新日期:2010-02-26 00:00:00
abstract::The benefits and risks of nutritional therapies in the prevention and management of infectious diseases in the developed world are reviewed. There is strong evidence that early enteral feeding of patients prevents infections in a variety of traumatic and surgical illnesses. There is, however, little support for simila...
journal_title:Nutrition journal
pub_type: 杂志文章,评审
doi:10.1186/1475-2891-5-21
更新日期:2006-09-04 00:00:00
abstract:BACKGROUND:Recent studies have shown that body image perception is an important factor in weight control and may be influenced by culture and ethnicity. The aim of the present study was to assess the relationship between immigrant status of the mother and weight status and body image perception of the child. METHODS:I...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/1475-2891-11-85
更新日期:2012-10-15 00:00:00
abstract:BACKGROUND:Adolescence is a crucial period for development of dietary behaviors that continue into adulthood and influence the risk of chronic diseases later in life. The aim of this study was to determine the eating patterns of adolescents' and their compliance with the Food Guide Pyramid. METHODS:625 students, aged ...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/1475-2891-9-67
更新日期:2010-12-19 00:00:00
abstract:BACKGROUND:Dietary intake of vitamin K has been reported to reduce coronary artery calcification (CAC) and cardiovascular events. However, it is unknown whether supplemental menaquinone (MK)-4 can reduce CAC or arterial stiffness. To study the effect of MK-4 supplementation on CAC and brachial ankle pulse wave velocity...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/s12937-016-0175-8
更新日期:2016-05-12 00:00:00
abstract:BACKGROUND:Dietary assessment methods that are user-friendly, simple, yet valid are of interest to both researchers and participants, particularly for use in disadvantaged settings, where language barriers and low levels of education are often present. We tested if parents taking photos of what children ate, using mobi...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/s12937-020-00558-4
更新日期:2020-05-27 00:00:00
abstract:INTRODUCTION:Despite recent interest in the use of ketogenic diets (KDs) for cancer, evidence of beneficial effects is lacking. This study examined the impact of a randomly assigned KD on quality of life, physical activity and biomarkers in patients with breast cancer. METHOD:A total of 80 patients with locally advanc...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/s12937-020-00596-y
更新日期:2020-08-22 00:00:00
abstract:BACKGROUND:Sleep related breathing disorders (SRBD) are associated with increased morbidity and mortality and weight loss is recommended to overweight or obese patients with SRBD. However, maintenance of weight loss is difficult to achieve and strategies for weight loss maintenance is needed. Orlistat is a pharmacologi...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/1475-2891-10-21
更新日期:2011-03-08 00:00:00
abstract:BACKGROUND:The consumption of fruit is generally associated with better health, but also higher socioeconomic status (SES). Most previous studies evaluating consumption of fruits have not separated 100% fruit juice and whole fruit, which may conceal interesting patterns in consumption. OBJECTIVE:To estimate demographi...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/1475-2891-14-3
更新日期:2015-01-05 00:00:00
abstract:BACKGROUND:Multiple micronutrient deficiencies, in particular iron deficiency anaemia (IDA) is a severe public health problem in Lao People's Democratic Republic (Lao PDR). Because of the practical difficulties encountered in improving the nutritional adequacy of traditional complementary foods and the limitations asso...
journal_title:Nutrition journal
pub_type: 杂志文章,随机对照试验
doi:10.1186/1475-2891-10-129
更新日期:2011-11-24 00:00:00
abstract:BACKGROUD:Chromium has been suggested playing a role in alleviating diabetes, insulin resistance and lipid anomalies, but the effect on metabolic syndrome (MetS) in humans remains controversial. METHODS:We conducted a matched case-control study in a Chinese population, involving 2141 MetS cases and 2141 healthy contro...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/s12937-020-00625-w
更新日期:2020-09-23 00:00:00
abstract::The number of individuals with age-related cognitive impairment is rising dramatically in the UK and globally. There is considerable interest in the general hypothesis that improving the diet of older people may slow the progression of cognitive decline. To date, there has been little attention given to the possible p...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/1475-2891-5-20
更新日期:2006-08-31 00:00:00
abstract:BACKGROUND:Consumption of sugar-sweetened beverages, such as soda, have been shown to play an important role in weight gain. Although soda consumption has been associated with body mass index (BMI) in many studies, it has been difficult to ascertain a true causal relationship between soda consumption and BMI for two re...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/s12937-017-0269-y
更新日期:2017-08-22 00:00:00
abstract:BACKGROUND:Increasing prevalence of obesity and overweight in the Western world, continue to be a major health threat and is responsible for increased health care costs. Dietary intervention studies show a strong positive association between saturated fat intake and the development of obesity and cardiovascular disease...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/1475-2891-10-53
更新日期:2011-05-18 00:00:00
abstract:BACKGROUND:Limited data exist on the contribution of dietary sources of arsenic to an individual's total exposure, particularly in populations with exposure via drinking water. Here, the association between diet and toenail arsenic concentrations (a long-term biomarker of exposure) was evaluated for individuals with me...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/1475-2891-12-149
更新日期:2013-11-16 00:00:00
abstract:BACKGROUND:Recommendations for daily dietary vegetable intake were increased in the 2005 USDA Dietary Guidelines as consumption of a diet rich in vegetables has been associated with lower risk of certain chronic health disorders including cardiovascular disease. However, vegetable consumption in the United States has d...
journal_title:Nutrition journal
pub_type: 杂志文章,随机对照试验
doi:10.1186/1475-2891-9-38
更新日期:2010-09-17 00:00:00
abstract:BACKGROUND:Multiple specialized nutritious food options are programmed for supplementation in humanitarian and development settings. However, comparative cost-effectiveness evidence is lacking, let alone incorporation of perspectives from uncompensated stakeholders. A Burkina Faso trial evaluated the cost-effectiveness...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/s12937-020-00535-x
更新日期:2020-02-27 00:00:00
abstract::Childhood obesity has reached epidemic levels in developed countries. Twenty five percent of children in the US are overweight and 11% are obese. Overweight and obesity in childhood are known to have significant impact on both physical and psychological health. The mechanism of obesity development is not fully underst...
journal_title:Nutrition journal
pub_type: 杂志文章,评审
doi:10.1186/1475-2891-4-24
更新日期:2005-09-02 00:00:00
abstract:BACKGROUND:Healthier dietary patterns are generally more costly than less healthy patterns, but dietary costs may be more important for dietary quality in lower educated and ethnic minority groups. The aim of this study was to investigate the association between dietary costs and dietary quality and interactions with e...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/s12937-019-0445-3
更新日期:2019-03-28 00:00:00
abstract:BACKGROUND:Comprehensive assessment of dietary intakes of foods and nutrients in Filipino adults are lacking. This study evaluated energy and nutrient intakes and food sources of key nutrients consumed by Filipino adults. METHODS:The participants were from the 2013 National Nutrition Survey wherein food intake of youn...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/s12937-019-0481-z
更新日期:2019-10-10 00:00:00
abstract:BACKGROUND:Iodine intake is considered to be high in Japan due to regular seaweed consumption. Subgroups that do not have a traditional Japanese-style diet may consume insufficient amounts of iodine. METHOD:Three hundred and ninety apparently healthy adults (195 men and 195 women) aged 20 to 69 years from 20 areas thr...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/s12937-015-0116-y
更新日期:2015-12-30 00:00:00
abstract:BACKGROUND:Low diet quality and depression symptoms are independently associated with poor glycemic control in subjects with type 2 diabetes (T2D); however, the relationship between them is unclear. The aim of this study was to determine the association between diet quality and symptoms of depression among Cuban-Americ...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/1475-2891-10-135
更新日期:2011-12-09 00:00:00
abstract::Nonalcoholic fatty liver disease (NAFLD) is characterized by fat deposition in hepatocytes, and a strong association with nutritional factors. Dietary fatty acids are classified according to their biochemical properties, which confer their bioactive roles. Monounsaturated fatty acids have a dual role in various human ...
journal_title:Nutrition journal
pub_type: 杂志文章,评审
doi:10.1186/s12937-016-0191-8
更新日期:2016-08-02 00:00:00
abstract:BACKGROUND:This study examined the association of breakfast consumption, and the type of breakfast consumed, with body mass index (BMI; kg/m(2)) and prevalence rates and odds ratios (OR) of overweight/obesity among Canadian adults. These associations were examined by age group and sex. METHODS:We used data from non-pr...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/s12937-016-0151-3
更新日期:2016-03-31 00:00:00
abstract:BACKGROUND:The 12-month Healthy Foods North intervention program was developed to improve diet among Inuit and Inuvialuit living in Arctic Canada and assess the impact of the intervention established for the communities. METHODS:A quasi-experimental study randomly selected men and women (≥19 years of age) in six remot...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/1475-2891-13-68
更新日期:2014-07-04 00:00:00
abstract:BACKGROUND:Aging is a process associated with physiological changes such as in body composition, energy expenditure and physical activity. Data on energy and nutrient intake adequacy among elderly is important for disease prevention, health maintenance and program development. METHODS:This descriptive cross-sectional ...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/1475-2891-8-19
更新日期:2009-05-04 00:00:00