Abstract:
INTRODUCTION:Cinnamon is currently marketed as a remedy for obesity, glucose intolerance, diabetes mellitus and dyslipidaemia. Integrative medicine is a new concept that combines conventional treatment with evidence-based complementary therapies. AIM:The aim of this review is to critically evaluate the experimental evidence available for cinnamon in improving glycaemic targets in animal models and humans. RESULTS:Insulin receptor auto-phosphorlylation and de-phosphorylation, glucose transporter 4 (GLUT-4 ) receptor synthesis and translocation, modulation of hepatic glucose metabolism through changes in Pyruvate kinase (PK) and Phosphenol Pyruvate Carboxikinase (PEPCK), altering the expression of PPAR (γ) and inhibition of intestinal glucosidases are some of the mechanisms responsible for improving glycaemic control with cinnamon therapy. We reviewed 8 clinical trials that used Cinnamomum cassia in aqueous or powder form in doses ranging from 500 mg to 6 g per day for a duration lasting from 40 days to 4 months as well as 2 clinical trials that used cinnamon on treatment naïve patients with pre-diabetes. An improvement in glycaemic control was seen in patients who received Cinnamon as the sole therapy for diabetes, those with pre-diabetes (IFG or IGT) and in those with high pre-treatment HbA1c. In animal models, cinnamon reduced fasting and postprandial plasma glucose and HbA1c. CONCLUSION:Cinnamon has the potential to be a useful add-on therapy in the discipline of integrative medicine in managing type 2 diabetes. At present the evidence is inconclusive and long-term trials aiming to establish the efficacy and safety of cinnamon is needed. However, high coumarin content of Cinnamomum cassia is a concern, but Cinnamomum zeylanicum with its low coumarin content would be a safer alternate.
journal_name
Nutr Jjournal_title
Nutrition journalauthors
Medagama ABdoi
10.1186/s12937-015-0098-9subject
Has Abstractpub_date
2015-10-16 00:00:00pages
108issn
1475-2891pii
10.1186/s12937-015-0098-9journal_volume
14pub_type
杂志文章,评审abstract:BACKGROUND:This study investigated the effect of fermented milk supplementation on glucose metabolism associated with muscle damage after acute exercise in humans. METHODS:Eighteen healthy young men participated in each of the three trials of the study: rest, exercise with placebo, and exercise with fermented milk. In...
journal_title:Nutrition journal
pub_type: 杂志文章,随机对照试验
doi:10.1186/1475-2891-12-83
更新日期:2013-06-16 00:00:00
abstract:BACKGROUND:Few studies have examined whether dietary factors might affect blood pressure in children. We purposed to investigate whether seaweed intake is associated with blood pressure level among Japanese preschool children. METHODS:The design of the study was cross-sectional and it was conducted in autumn 2006. Sub...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/1475-2891-10-83
更新日期:2011-08-10 00:00:00
abstract:BACKGROUND:Limited data exist on the contribution of dietary sources of arsenic to an individual's total exposure, particularly in populations with exposure via drinking water. Here, the association between diet and toenail arsenic concentrations (a long-term biomarker of exposure) was evaluated for individuals with me...
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pub_type: 杂志文章
doi:10.1186/1475-2891-12-149
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abstract:BACKGROUND:Few localized food frequency questionnaires (FFQ) have been developed and used in Chinese nutrition surveys despite China's large population and diverse dietary habits. METHOD:We analyzed data collected in two waves (six months apart) of the Shanghai Diet and Health Study in 2012-2013, from 1623 Shanghai re...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/s12937-019-0454-2
更新日期:2019-05-23 00:00:00
abstract::Public health policies, including in Europe, are considering measures and recommendations to limit the intake of added or free sugars. For such policies to be efficient and monitored, a precise knowledge of the current situation regarding sugar intake in Europe is needed. This review summarizes published or re-analyze...
journal_title:Nutrition journal
pub_type: 杂志文章,评审
doi:10.1186/s12937-016-0225-2
更新日期:2017-01-21 00:00:00
abstract:BACKGROUND:Early enteral nutrition is recommended in cases of critical illness. It is unclear whether this recommendation is of most benefit to extremely ill patients. We aim to determine the association between illness severity and commencement of enteral feeding. METHODS:One hundred and eight critically ill patients...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/1475-2891-11-30
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abstract:BACKGROUND:Obesity leads to an increase in inflammation and insulin resistance. This study determined antioxidant activity of flaxseed and its role in inflammation and insulin resistance in obese glucose intolerant people. METHODS:Using a randomized crossover design, nine obese glucose intolerant people consumed 40 g ...
journal_title:Nutrition journal
pub_type: 杂志文章,随机对照试验
doi:10.1186/1475-2891-10-44
更新日期:2011-05-09 00:00:00
abstract:BACKGROUND:There are several methods of assessing nutritional status in cancer of which serum albumin is one of the most commonly used. In recent years, the role of malnutrition as a predictor of survival in cancer has received considerable attention. As a result, it is reasonable to investigate whether serum albumin h...
journal_title:Nutrition journal
pub_type: 杂志文章,评审
doi:10.1186/1475-2891-9-69
更新日期:2010-12-22 00:00:00
abstract:BACKGROUND:Pregnant women, neonates, and school-age children are vulnerable to iodine deficiency. The iodine contents in the environment (drinking water and household salt for cooking) vary by geographical location in China. The aim of this study was to assess the iodine status in vulnerable groups from different geogr...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/s12937-020-0525-4
更新日期:2020-01-21 00:00:00
abstract::In this letter, we respond to the comments raised by Visaria et al. in their letter to the editor about the publication "Association of dietary ω-3 and ω-6 fatty acids intake with cognitive performance in older adults: National Health and Nutrition Examination Survey (NHANES) 2011-2014". We have further adjusted for s...
journal_title:Nutrition journal
pub_type: 评论,信件
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更新日期:2020-09-11 00:00:00
abstract:BACKGROUND:Among natural compounds, present in every day diet, flavonoids have shown beneficial effect in prevention of cardiovascular diseases that can be attributed, at least partially to the described antiaggregatory activity i.e. antiplatelet effects of flavonoids. Due to the ever increasing pharmacological interes...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/1475-2891-10-73
更新日期:2011-07-11 00:00:00
abstract:BACKGROUND:Fish consumption and intake of omega-3 fatty acids from fish are associated with a lower risk of cardiovascular disease. However, a prospective study from northern Sweden showed that high consumption of fish is associated with an increased risk of stroke in men, but not in women. The current study aimed to d...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/1475-2891-11-101
更新日期:2012-12-04 00:00:00
abstract:BACKGROUND:Our previous studies demonstrated that dietary supplementation with milk fat globule membrane (MFGM) combined with habitual exercise improved muscle strength by stimulating neuromuscular development in mice. This study aimed to demonstrate the beneficial effects of dietary MFGM supplementation plus regular e...
journal_title:Nutrition journal
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12937-015-0073-5
更新日期:2015-08-25 00:00:00
abstract:BACKGROUND:A number of studies have reported the association between dietary patterns and the risk of chronic kidney disease (CKD), however a consistent perspective hasn't been established to date. Herein, we conducted this systematic review and meta-analysis of observational studies to assess the association between d...
journal_title:Nutrition journal
pub_type: 杂志文章,评审
doi:10.1186/s12937-020-00661-6
更新日期:2021-01-08 00:00:00
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journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/1475-2891-5-27
更新日期:2006-10-16 00:00:00
abstract:BACKGROUND:Excessive body fat is the leading cause of many metabolic disorders. Therefore, assessing levels of body fat associated with risk of disease in specific populations is crucial. The present study aimed to identify optimal cut-off values of body fat composition including total body fat, body fat percentage, vi...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/s12937-020-00569-1
更新日期:2020-07-25 00:00:00
abstract::Certain dietary patterns, in which fruits and nuts are featured prominently, reduce risk of diabetes and cardiovascular disease. However, estimated fruit consumption historically in the U.S. has been lower than recommendations. Dried fruit intake is even lower with only about 6.9 % of the adult population reporting an...
journal_title:Nutrition journal
pub_type: 杂志文章,评审
doi:10.1186/s12937-016-0142-4
更新日期:2016-03-05 00:00:00
abstract:BACKGROUND:The increase in the burden of chronic diseases linked to the nutrition transition and associated dietary and lifestyle changes is of growing concern in south and east Mediterranean countries and adolescents are at the forefront of these changes. This study assessed dietary intake and association with socio-e...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/1475-2891-10-38
更新日期:2011-04-24 00:00:00
abstract:BACKGROUND:Several studies have shown that cocoa and cocoa-containing foods have the potential to lower blood pressure and improve endothelial function. Most of the studies reporting the beneficial effects of dark chocolate on blood pressure have been short (≤ 4 weeks). The aim of the present 8-wks (weeks) study was to...
journal_title:Nutrition journal
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12937-015-0075-3
更新日期:2015-08-22 00:00:00
abstract:BACKGROUND:Consumption of nuts improves cardio-metabolic risk factors in clinical trials and relates to lower risk of cardiovascular disease (CVD) in prospective observational studies. However, there has not been an adequately powered randomized controlled trial to test if nuts supplementation actually reduces incident...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/s12937-020-00660-7
更新日期:2021-01-06 00:00:00
abstract::A sex- and gender-informed approach to study design, analysis and reporting has particular relevance to the transgender and gender nonconforming population (TGNC) where sex and gender identity differ. Notable research gaps persist related to dietary intake, validity and reliability of nutrition assessment methods, and...
journal_title:Nutrition journal
pub_type: 信件
doi:10.1186/s12937-021-00662-z
更新日期:2021-01-15 00:00:00
abstract:BACKGROUND:Low diet quality and depression symptoms are independently associated with poor glycemic control in subjects with type 2 diabetes (T2D); however, the relationship between them is unclear. The aim of this study was to determine the association between diet quality and symptoms of depression among Cuban-Americ...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/1475-2891-10-135
更新日期:2011-12-09 00:00:00
abstract:BACKGROUND:This study explored the influence of cigarette smoking and food consumption patterns on BMI after adjusting for various socio-demographic characteristics. Since weight-based stereotypes may have an impact on smoking behaviour and both obesity and smoking have been associated with detrimental health effects, ...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/s12937-018-0408-0
更新日期:2018-11-05 00:00:00
abstract:BACKGROUND:Comprehensive assessment of dietary intakes of foods and nutrients in Filipino adults are lacking. This study evaluated energy and nutrient intakes and food sources of key nutrients consumed by Filipino adults. METHODS:The participants were from the 2013 National Nutrition Survey wherein food intake of youn...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/s12937-019-0481-z
更新日期:2019-10-10 00:00:00
abstract:BACKGROUND:Nocturnal eating have recently increased. Serum phosphorus levels and regulators of phosphorus have circadian variations, so it is suggested that the timing of eating may be important in controlling serum phosphorus levels. However, there have been no reports on the effects of nocturnal eating on phosphorus ...
journal_title:Nutrition journal
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12937-015-0096-y
更新日期:2015-10-08 00:00:00
abstract:BACKGROUND:The eating habits have changed in the last few decades, but few studies prioritize the food consumption of farmers and the rural population. Therefore, the objective of this study was explore the sociodemographic, occupational and lifestyle factors to the high adherence these dietary patterns. METHODS:This ...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/s12937-020-00542-y
更新日期:2020-03-24 00:00:00
abstract:OBJECTIVE:To evaluate the association between the consumption of unhealthy foods in children under one year and the education level of the mothers, data obtained from participants of the II Survey on the prevalence of breastfeeding in the Brazilian capitals and the Federal District in 2008 was analyzed. METHODS:During...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/1475-2891-13-33
更新日期:2014-04-03 00:00:00
abstract:BACKGROUND:High level of serum cholesterol is considered to be a major risk factor for cardiovascular disease (CVD). A double-blinded, randomized, placebo-controlled trial was performed to test the hypothesis that a daily intake of Chlorella may improve serum lipid profile through enhancement of serum carotenoid concen...
journal_title:Nutrition journal
pub_type: 杂志文章,随机对照试验
doi:10.1186/1475-2891-13-57
更新日期:2014-06-11 00:00:00
abstract::Added sugar regulations and recommendations have been proposed by policy makers around the world. With no universal definition, limited access to added sugar values in food products and no analytical difference from intrinsic sugars, added sugar recommendations present a unique challenge. Average added sugar intake by...
journal_title:Nutrition journal
pub_type: 杂志文章,评审
doi:10.1186/s12937-015-0114-0
更新日期:2015-12-12 00:00:00
abstract:BACKGROUND:Isoflavones comprise a class of phytoestrogens that resemble human estrogen in chemical structure, and have weak estrogenic effects. Because estrogen modulates sleep duration and quality, we hypothesized that isoflavones would have a beneficial effect on sleep status in a way similar to estrogen. We conducte...
journal_title:Nutrition journal
pub_type: 杂志文章
doi:10.1186/s12937-015-0117-x
更新日期:2015-12-29 00:00:00