Involvement of the cytoskeleton in the movement of cortical granules during oocyte maturation, and cortical granule anchoring in mouse eggs.

abstract：:During development, cells craft an impressive array of actin-based structures, mediating events as diverse as cytokinesis, apical constriction, and cell migration. One challenge is to determine how cells regulate actin assembly and disassembly to carry out these cell behaviors. During Drosophila oogenesis diverse cell...

journal_title：Developmental biology

authors： Gates J,Nowotarski SH,Yin H,Mahaffey JP,Bridges T,Herrera C,Homem CC,Janody F,Montell DJ,Peifer M

更新日期：2009-09-01 00:00:00

abstract：:Carbohydrate chains on the t12 mutant embryos were analyzed. No abnormalities of the synthesis of the carbohydrate chains were observed in the t12 homozygotes until the late morula stage, when radiolabeled carbohydrate chains were analyzed by Sephadex G-50 column chromatography. Furthermore, polarization of the Con A ...

journal_title：Developmental biology

authors： Iwakura Y,Nozaki M

更新日期：1988-08-01 00:00:00

abstract：:A major cause for vision impairment and blindness in industrialized countries is the loss of the light-sensing retinal tissue in the eye. Photoreceptor damage is one of the main characteristics found in retinal degeneration diseases, such as Retinitis Pigmentosa or age-related macular degeneration. The lack of effecti...

journal_title：Developmental biology

authors： Llonch S,Carido M,Ader M

更新日期：2018-01-15 00:00:00

abstract：:Repair and regeneration of adult skeletal muscle are mediated by satellite cells. In healthy muscle these rare mononucleate muscle precursor cells are mitotically quiescent. Upon muscle injury or degeneration, members of this self-renewing pool are activated to proliferate and then differentiate. Here we analyzed in s...

journal_title：Developmental biology

authors： Cornelison DD,Wold BJ

更新日期：1997-11-15 00:00:00

abstract：:Polychaete annelids and arthropods are both segmented protostome invertebrates. To investigate whether the segmented body plan of these two phyla share a common molecular ground pattern, we report the developmental expression of orthologues of the arthropod segment polarity genes engrailed (en), hedgehog (hh), and win...

journal_title：Developmental biology

authors： Seaver EC,Kaneshige LM

更新日期：2006-01-01 00:00:00

abstract：:The cardiac neural crest contains ectomesenchymal and neural anlagen that are necessary for normal heart development. It is not known whether other regions of the neural crest are capable of supporting normal heart development. In the experiments reported herein, quail donor embryos provided cardiac, trunk, or mesence...

journal_title：Developmental biology

authors： Kirby ML

更新日期：1989-08-01 00:00:00

abstract：:Expression of constitutively active Src protein tyrosine kinase in Xenopus oocytes has been shown to accelerate oocyte maturation suggesting that Src may be involved in meiotic progression. However, meiotic regulation of endogenous Src kinase in oocytes has not been investigated in detail. To address this problem, we ...

journal_title：Developmental biology

authors： Tokmakov A,Iwasaki T,Itakura S,Sato K,Shirouzu M,Fukami Y,Yokoyama S

更新日期：2005-02-15 00:00:00

abstract：:Skeletal muscles of the avian limb are derived from mononucleated myogenic precursor cells (myoblasts) that migrate into the somatopleural mesoderm of the developing limb bud from the ventrolateral dermomyotome of limb adjacent somites. In the present study, we utilized replication-deficient lacZ-encoding retroviruses...

journal_title：Developmental biology

authors： Rees E,Young RD,Evans DJ

更新日期：2003-01-15 00:00:00

abstract：:The development of germ cells is a highly ordered process that begins during fetal growth and is completed in the adult. Epigenetic modifications that occur in germ cells are important for germ cell function and for post-fertilization embryonic development. We have previously shown that male germ cells in the adult mo...

journal_title：Developmental biology

authors： Oakes CC,La Salle S,Smiraglia DJ,Robaire B,Trasler JM

更新日期：2007-07-15 00:00:00

abstract：:Cytotrophoblasts are specialized epithelial cells of the human placenta that differentiate to acquire tumor-like properties that allow them to invade the uterus. Concurrently, they develop endothelial-like characteristics. This transformation allows cytotrophoblasts to replace the maternal cells that line uterine vess...

journal_title：Developmental biology

authors： Zhou Y,Bellingard V,Feng KT,McMaster M,Fisher SJ

更新日期：2003-11-01 00:00:00

abstract：:Previous studies have shown CD34 family member Podocalyxin is required for epithelial lumen formation in vitro. We demonstrate that Endoglycan, a CD34 family member with homology to Podocalyxin, is produced prior to lumen formation in developing nephrons. Endoglycan localizes to Rab11-containing vesicles in nephron pr...

journal_title：Developmental biology

authors： Yang Z,Zimmerman SE,Tsunezumi J,Braitsch C,Trent C,Bryant DM,Cleaver O,González-Manchón C,Marciano DK

更新日期：2016-10-01 00:00:00

abstract：:We have investigated sensillum development in Drosophila embryos homozygous for mutations in the locus string (stg). In these embryos, cell division is blocked following blastoderm formation. This permits a study of the differentiative fate of undivided precursor cells, in particular those giving rise to the larval se...

journal_title：Developmental biology

authors： Hartenstein V,Posakony JW

更新日期：1990-03-01 00:00:00

abstract：:Isotopes of a number of crustacean myofibrillar proteins have been identified with sodium dodecyl sulfate-polyacrylamide electrophoresis, and their distribution in muscles of the snapping shrimp has been examined. Fast-slow differences in distribution have been observed for myosin light chains and tropomyosin. In cont...

journal_title：Developmental biology

authors： Quigley MM,Mellon D Jr

更新日期：1984-11-01 00:00:00

abstract：:A functional ribosomal protein mRNA, encoding the 60 S subunit protein L1, has been synthesized in vitro using bacteriophage SP6 RNA polymerase. This mRNA directs the synthesis of a product indistinguishable from L1 protein purified from Xenopus ovarian ribosomes. Our results show that L1 synthesis in stage VI oocytes...

journal_title：Developmental biology

authors： Baum EZ,Hyman LE,Wormington WM

更新日期：1988-03-01 00:00:00

abstract：:We have reported previously that sequence-specific adenylations and deadenylations accompany changes in the translation of maternal mRNA following fertilization of Spisula oocytes (E.T. Rosenthal, T.R. Tansey, and J.V. Ruderman, 1983, J. Mol. Biol. 166, 309-327). The data presented here confirm and extend those observ...

journal_title：Developmental biology

authors： Rosenthal ET,Ruderman JV

更新日期：1987-05-01 00:00:00

abstract：:The lens in the vertebrate eye has been shown to be critical for proper differentiation of the surrounding ocular tissues including the cornea, iris and ciliary body. In mice, previous investigators have assayed the consequences of molecular ablation of the lens. However, in these studies, lens ablation was initiated ...

journal_title：Developmental biology

authors： Zhang Y,Burgess D,Overbeek PA,Govindarajan V

更新日期：2008-11-01 00:00:00

abstract：:The polypeptide labeling patterns of somatic cells, gonidia (asexual reproductive cells), embryos, and juvenile spheroids of Volvox carteri cultures synchronized by a light/dark cycle were studied as a function of developmental stage and incubation condition. Specimens were exposed to 35SO=4 for 1-hr periods at select...

journal_title：Developmental biology

authors： Kirk DL,Kirk MM

更新日期：1983-04-01 00:00:00

abstract：:Several genomic clones were isolated from a Drosophila library screened with cDNA prepared from abundant adult female mRNA. Cytoplasmic dot hybridizations have shown that the genes in all of these clones are expressed only in posteclosion (stages 8-14) follicles. One set of overlapping clones (lambda 20, lambda 28, an...

journal_title：Developmental biology

authors： Higgins MJ,Walker VK,Holden JA,White BN

更新日期：1984-09-01 00:00:00

abstract：:The aim of this study was to evaluate the role segmentation plays in the determination of neuronal identity in the hindbrain. We focused on two specific sets of hindbrain neurons, namely, the vestibulospinal and vestibulo-ocular neurons, which comprise distinct groups that can be identified and distinguished by virtue...

journal_title：Developmental biology

authors： Díaz C,Puelles L,Marín F,Glover JC

更新日期：1998-10-01 00:00:00

abstract：:Biologists have long recognized that dramatic bending of a cell sheet may be driven by even modest shrinking of the apical sides of cells. Cell shape changes and tissue movements like these are at the core of many of the morphogenetic movements that shape animal form during development, driving processes such as gastr...

journal_title：Developmental biology

authors： Sawyer JM,Harrell JR,Shemer G,Sullivan-Brown J,Roh-Johnson M,Goldstein B

更新日期：2010-05-01 00:00:00

abstract：:Voltage-gated Na(+) and K(+) channels are localized to distinct subcellular domains in mammalian myelinated nerve fibers. Specifically, Na(+) channels are clustered in high densities at nodes of Ranvier, while K(+) channels are found in juxtaparanodal zones just beyond regions of axoglial contact where sequential laye...

journal_title：Developmental biology

authors： Rasband MN,Trimmer JS

更新日期：2001-08-01 00:00:00

abstract：:Antenna structure varies widely among insects, in contrast to the well-conserved structure of legs. The adult capitate antenna of the red flour beetle, Tribolium castaneum, is composed of eleven articles, organized into four distinct morphological regions (scape, pedicel, funicle and club). Here, we report the use of ...

journal_title：Developmental biology

authors： Angelini DR,Kikuchi M,Jockusch EL

更新日期：2009-03-01 00:00:00

abstract：:In medusae of the hydrozoan Cytaeis uchidae, oocyte meiotic maturation and spawning occur as a consequence of dark-light transition. In this study, we investigated the mechanism underlying the initiation of meiotic maturation using in vitro (isolated oocytes from ovaries) and in vivo (ovarian oocytes in medusae) syste...

journal_title：Developmental biology

authors： Takeda N,Kyozuka K,Deguchi R

更新日期：2006-10-01 00:00:00

abstract：:In vertebrates, the Müllerian duct elongates along the Wolffian duct, a mesonephric structure that is required for Müllerian duct formation. Recently, several genes required for initial Müllerian duct formation have been identified. However, the precise mechanism of Müllerian duct elongation remains to be elucidated. ...

journal_title：Developmental biology

authors： Fujino A,Arango NA,Zhan Y,Manganaro TF,Li X,MacLaughlin DT,Donahoe PK

更新日期：2009-01-15 00:00:00

abstract：:Development of the mammalian external genitalia is controlled by a network of signaling molecules and transcription factors. Because FGF signaling plays a central role in this complicated morphogenetic process, we investigated the role of Sprouty genes, which are important intracellular modulators of FGF signaling, du...

journal_title：Developmental biology

authors： Ching ST,Cunha GR,Baskin LS,Basson MA,Klein OD

更新日期：2014-02-01 00:00:00

abstract：:The dopaminergic neurons of the basal ganglia play critical roles in CNS function and human disease, but specification of dopamine neuron phenotype is poorly understood in vertebrates. We performed an in vivo screen in zebrafish to identify dopaminergic neuron enhancers, in order to facilitate studies on the specifica...

journal_title：Developmental biology

authors： Fujimoto E,Stevenson TJ,Chien CB,Bonkowsky JL

更新日期：2011-04-15 00:00:00

abstract：:The role of the wound epithelium in amphibian limb regeneration is not understood. We showed previously that monoclonal antibody (mAb) WE3 stains the wound epithelium but not skin epidermis, suggesting that the WE3 antigen may be a marker for, or be important in, the function of the wound epithelium. In the present st...

journal_title：Developmental biology

authors： Goldhamer DJ,Tomlinson BL,Tassava RA

更新日期：1989-10-01 00:00:00

abstract：:We have used in situ hybridization and RNA blotting analysis to compare the timing of accumulation of poly(A) and alpha-subtype histone mRNA during oogenesis in the sea urchin Strongylocentrotus purpuratus. In situ hybridization with 3H-poly(U) shows that the content of poly(A) in the developing oocyte increases four-...

journal_title：Developmental biology

authors： Angerer LM,DeLeon DV,Angerer RC,Showman RM,Wells DE,RafF RA

更新日期：1984-02-01 00:00:00

abstract：:It has been suggested that the mesonephros has a role in normal limb development. This hypothesis was directly tested by removing the mesonephros adjacent to the presumptive limb region of stage 12-18 chick embryos using microsurgery or laser ablation. The experimental manipulation resulted in reduced limb outgrowth o...

journal_title：Developmental biology

authors： Geduspan JS,Solursh M

更新日期：1992-05-01 00:00:00

abstract：FOREWORD:The neural crest has been the main object of my investigations during my career in science, up to now. It is a fascinating topic for an embryologist because of its two unique characteristics: its large degree of multipotency and the fact that its development involves a phase during which its component cells mi...

journal_title：Developmental biology

authors： Le Douarin NM,Dupin E

更新日期：2018-12-01 00:00:00