Changes in myofibrillar gene expression during fiber-type transformation in the claw closer muscles of the snapping shrimp, Alpheus heterochelis.

abstract：:Exposure of Xenopus animal pole explants to transforming growth factor beta 2 (TGF-beta 2) induced the sequential expression of muscle nicotinic acetylcholine receptor (AChRs) isoforms and their corresponding mRNAs in cells which normally give rise to ectoderm. Single channel recordings revealed two functional classes...

journal_title：Developmental biology

authors： Reuer Q,Kullberg RW,Owens JL

更新日期：1994-11-01 00:00:00

abstract：:Eight series of mouse chimeras were produced by aggregating 8-cell embryos that differed at the Gpi-1s locus, encoding glucose phosphate isomerase (GPI-1). Chimeric blastocysts (Gpi-1sa/Gpi-1sa <--> Gpi-1sb/Gpi-1sb) were transferred to pseudopregnant females, which produced only GPI-1C enzyme. Quantitative electrophor...

journal_title：Developmental biology

authors： West JD,Flockhart JH,Keighren M

更新日期：1995-03-01 00:00:00

abstract：:The endoderm of C. elegans arises entirely from a single progenitor cell, the E blastomere, whose identity is specified by GATA type transcription factors, including END-1. In response to an inductive interaction mediated through Wnt/MAP kinase signaling pathways, POP-1, a Lef/Tcf-type transcription factor, restricts ...

journal_title：Developmental biology

authors： Witze ES,Field ED,Hunt DF,Rothman JH

更新日期：2009-03-01 00:00:00

abstract：:Developmental patterning and growth of the vertebrate digestive and respiratory tracts requires interactions between the epithelial endoderm and adjacent mesoderm. The esophagus is a specialized structure that connects the digestive and respiratory systems and its normal development is critical for both. Shh signaling...

journal_title：Developmental biology

authors： Korzh S,Winata CL,Zheng W,Yang S,Yin A,Ingham P,Korzh V,Gong Z

更新日期：2011-11-15 00:00:00

abstract：:Replication-dependent histone genes in the mouse and Xenopus share a common regulatory element within the protein-encoding sequence called the CRAS alpha element (coding region activating sequence alpha) which has been shown to mediate normal expression in vivo and to interact with nuclear factors in vitro in a cell c...

journal_title：Developmental biology

authors： Ficzycz A,Kaludov NK,Lele Z,Hurt MM,Ovsenek N

更新日期：1997-02-01 00:00:00

abstract：:Nematodes provide a useful experimental system with which to investigate the evolution of development at the cellular, genetic, and molecular levels. Building on an understanding of vulval development in Caenorhabditis elegans, analysis of vulval development has been extended to a number of other species in three fami...

journal_title：Developmental biology

authors： Sommer RJ,Sternberg PW

更新日期：1996-02-01 00:00:00

abstract：:Understanding the regulatory circuitry controlling myogenesis is critical to understanding developmental mechanisms and developmentally-derived diseases. We analyzed the transcriptional regulation of a Drosophila myogenic repressor gene, Holes in muscles (Him). Previously, Him was shown to inhibit Myocyte enhancer fac...

journal_title：Developmental biology

authors： Elwell JA,Lovato TL,Adams MM,Baca EM,Lee T,Cripps RM

更新日期：2015-04-15 00:00:00

abstract：:Prophase-arrested oocytes of Ruditapes philippinarum are triggered to undergo germinal vesicle breakdown under the influence of the neurohormone serotonin (5HT) and then arrest in metaphase 1. Our data show that these oocytes possess a single class of original 5HT receptors. Their binding parameters have been determin...

journal_title：Developmental biology

authors： Gobet I,Durocher Y,Leclerc C,Moreau M,Guerrier P

更新日期：1994-08-01 00:00:00

abstract：:Inhibitor of differentiation and DNA-binding (Id) proteins, Id1 to Id4, function in the regulation of cellular proliferation and differentiation. Id proteins have been shown to interact with bHLH proteins and other proteins involved in regulating cellular proliferation and differentiation, suggesting a widespread regu...

journal_title：Developmental biology

authors： Sakamoto S,Tateya T,Omori K,Kageyama R

更新日期：2020-04-15 00:00:00

abstract：:The dorsal-ventral axis of the Xenopus embryo is approximately determined by the point of sperm entry, which occurs randomly about the animal-vegetal axis of the egg. Two cytoplasmic components were studied whose spatial arrangements and local concentration patterns appear to reflect the forming dorsal-ventral axis. F...

journal_title：Developmental biology

authors： Phillips CR

更新日期：1985-06-01 00:00:00

abstract：:Interstitial cell migration was characterized in Hydra vulgaris (formerly H. attenuata) and the effects of axial position and tissue injury on migration were investigated. Migrating cells were labeled with the thymidine analog, bromodeoxyuridine, and grafted into unlabeled host polyps. Alternatively, cells were labele...

journal_title：Developmental biology

authors： Teragawa CK,Bode HR

更新日期：1990-03-01 00:00:00

abstract：:A fundamental issue during nervous system development is how individual cells are formed from the undefined precursors. Differentiated neurons and glia, two major cell types mediating neuronal function, are acquired from immature precursors via a series of explicit controls exerted by transcription factors such as pro...

journal_title：Developmental biology

authors： Mao H,Lv Z,Ho MS

更新日期：2012-10-01 00:00:00

abstract：:Recent results have demonstrated the occurrence of mRNA cap methylation in the sea urchin embryo following fertilization. It has been suggested that this methylation event is responsible for the translational activation of maternal histone mRNAs in these embryos. We have used aphidicolin, an effective inhibitor of bot...

journal_title：Developmental biology

authors： Showman RM,Leaf DS,Anstrom JA,Raff RA

更新日期：1987-05-01 00:00:00

abstract：:The neural crest is a transient and multipotent cell population arising at the edge of the neural plate in vertebrates. Recent findings highlight that neural crest patterning is initiated during gastrulation, i.e. earlier than classically described, in a progenitor domain named the neural border. This chapter reviews ...

journal_title：Developmental biology

authors： Milet C,Monsoro-Burq AH

更新日期：2012-06-01 00:00:00

abstract：:In the full grown oocyte of Xenopus laevis, a sodium permeability can be induced by depolarization to positive potential with current injection. Voltage-clamp analysis has shown that depolarization causes a long-lasting modification of the membrane during which voltage-gated sodium channels become functional. In the p...

journal_title：Developmental biology

authors： Baud C

更新日期：1983-10-01 00:00:00

abstract：:In this report we describe the development of a sensitive assay for gene expression in zebrafish embryos using beta-lactamase as a reporter gene. We show that injection of a green fluorescent substrate for beta-lactamase allows the detection of reporter gene expression in live embryos. The beta-lactamase enzyme cataly...

journal_title：Developmental biology

authors： Raz E,Zlokarnik G,Tsien RY,Driever W

更新日期：1998-11-15 00:00:00

abstract：:To analyse cell migration and the differentiation potential of migratory stem cells in Hydractinia, we generated animals with an eGFP reporter gene stably expressed and transmitted via the germline. The transgene was placed under the control of two different actin promoters and the promoter of elongation factor-1α. On...

journal_title：Developmental biology

authors： Künzel T,Heiermann R,Frank U,Müller W,Tilmann W,Bause M,Nonn A,Helling M,Schwarz RS,Plickert G

更新日期：2010-12-01 00:00:00

abstract：:Developmental pattern formation allows cells within a tissue or organ to coordinate their development and establish cell types in relationship to one another. To better characterize the developmental patterning events within one organ, the C. elegans hindgut, we have analyzed the expression pattern of several genes us...

journal_title：Developmental biology

authors： Sewell ST,Zhang G,Uttam A,Chamberlin HM

更新日期：2003-10-01 00:00:00

abstract：:Cell-cell fusion is a fundamental cellular process that is essential for development as well as fertilization. Myoblast fusion to form multinucleated skeletal muscle myotubes is a well studied, yet incompletely understood example of cell-cell fusion that is essential for formation of contractile skeletal muscle tissue...

journal_title：Developmental biology

authors： Duan R,Gallagher PJ

更新日期：2009-01-15 00:00:00

abstract：:A mutant gene dose-dependent inhibition of cerebellar granule cell neuron survival and neurite growth in dissociated cultures of cerebellum from 7-day-old heterozygous (+/wv) and homozygous (wv/wv) weaver mutant mice (M. Willinger, D. M. Margolis, and R. L. Sidman. (1981), J. Supramol. Struc. 17, 79-86) has previously...

journal_title：Developmental biology

authors： Willinger M,Margolis DM

更新日期：1985-01-01 00:00:00

abstract：:Vertebrate hematopoiesis is characterized by two evolutionally conserved phases of development, i.e., primitive hematopoiesis, which is a transient phenomenon in the early embryo, and definitive hematopoiesis, which takes place in the later stages. Beni fuji (bef) was originally isolated as a medaka mutant that has an...

journal_title：Developmental biology

authors： Moriyama A,Inohaya K,Maruyama K,Kudo A

更新日期：2010-09-15 00:00:00

abstract：:Cis-regulatory modules (CRMs) control spatiotemporal gene expression patterns in embryos. While measurement of quantitative CRM activities has become efficient, measurement of spatial CRM activities still relies on slow, one-by-one methods. To overcome this bottleneck, we have developed a high-throughput method that c...

journal_title：Developmental biology

authors： Guay CL,McQuade ST,Nam J

更新日期：2017-02-15 00:00:00

abstract：:We have investigated the function of the neurogenic gene Notch (N) during development of the adult sensilla of Drosophila. Heat pulses were applied to flies carrying the temperature-sensitive Notch allele Nts1 at different larval and pupal stages. We can show that the reduction of Notch+ function during a short interv...

journal_title：Developmental biology

authors： Hartenstein V,Posakony JW

更新日期：1990-11-01 00:00:00

abstract：:Mammalian sperm must acquire their fertilizing ability after a series of biochemical modifications in the female reproductive tract collectively called capacitation to undergo acrosomal exocytosis, a process that is essential for fertilization. Actin dynamics play a central role in controlling the process of exocytosi...

journal_title：Developmental biology

authors： Romarowski A,Battistone MA,La Spina FA,Puga Molina Ldel C,Luque GM,Vitale AM,Cuasnicu PS,Visconti PE,Krapf D,Buffone MG

更新日期：2015-09-15 00:00:00

abstract：:Auxin is implicated throughout plant growth and development. Although the effects of this plant hormone have been recognized for more than a century, it is only in the past two decades that light has been shed on the molecular mechanisms that regulate auxin homeostasis, signaling, transport, crosstalk with other hormo...

journal_title：Developmental biology

authors： Finet C,Jaillais Y

更新日期：2012-09-01 00:00:00

abstract：:Polyspermic Xenopus laevis eggs can be identified easily because of regions of pigment accumulation and white stripes, which arise by a nocodazole-sensitive process. Eggs containing up to four sperm are capable of forming a single embryonic axis. Dispermic eggs display two regions of pigment accumulation, one around e...

journal_title：Developmental biology

authors： Render JA,Elinson RP

更新日期：1986-06-01 00:00:00

abstract：:Metamorphosis involves the destruction of larval, the formation of adult and the transformation of larval into adult tissues. In this study, we demonstrate the role of the Drosophila nuclear proteins EAST and Chromator in tissue destruction and remodeling. To better understand the function of east, we performed a yeas...

journal_title：Developmental biology

authors： Wasser M,Bte Osman Z,Chia W

更新日期：2007-07-15 00:00:00

abstract：:Planarians are well-known for their exceptional regenerative abilities. This investigation focuses on the involvement of a Y-box protein, defined by the presence of a cold-shock domain, in regeneration-specific processes. Previous studies have shown that developmentally expressed Y-box proteins bind to mRNA molecules ...

journal_title：Developmental biology

authors： Salvetti A,Batistoni R,Deri P,Rossi L,Sommerville J

更新日期：1998-09-15 00:00:00

abstract：:Using optical imaging assays, we investigated the dynamics of acetylcholine receptors (AChRs) at laminin-associated clusters on cultured myotubes in the absence or presence of the nerve-derived clustering factor, agrin. Using fluorescence recovery after photobleaching (FRAP) on fluorescent bungarotoxin-labeled recepto...

journal_title：Developmental biology

authors： Bruneau EG,Macpherson PC,Goldman D,Hume RI,Akaaboune M

更新日期：2005-12-01 00:00:00

abstract：:Immature, Stage VI oocytes of Xenopus laevis fail to activate (i.e., to propagate a cortical reaction and elevate a fertilization envelope) when pricked or exposed to A23187. We determined the times during maturation when immature oocytes treated with progesterone in vitro developed the capacity to respond to pricking...

journal_title：Developmental biology

authors： Charbonneau M,Grey RD

更新日期：1984-03-01 00:00:00