Developmental patterning in the Caenorhabditis elegans hindgut.

Abstract:

:Developmental pattern formation allows cells within a tissue or organ to coordinate their development and establish cell types in relationship to one another. To better characterize the developmental patterning events within one organ, the C. elegans hindgut, we have analyzed the expression pattern of several genes using green fluorescent protein-based reporter transgenes. In wild-type animals, these genes are expressed in subsets of hindgut cells rather than in individual cell types. In mutant animals, we find that some, but not all, genes expressed in cells with altered development exhibit a corresponding alteration of gene expression. The results are consistent with a model where a combination of factors contribute to each cell's fate, and address how developmental information converges to specify cell types.

journal_name

Dev Biol

journal_title

Developmental biology

authors

Sewell ST,Zhang G,Uttam A,Chamberlin HM

doi

10.1016/s0012-1606(03)00352-x

subject

Has Abstract

pub_date

2003-10-01 00:00:00

pages

88-93

issue

1

eissn

0012-1606

issn

1095-564X

pii

S001216060300352X

journal_volume

262

pub_type

杂志文章
  • A spatially dynamic cohort of regulatory genes in the endomesodermal gene network of the sea urchin embryo.

    abstract::A gene regulatory network subcircuit comprising the otx, wnt8, and blimp1 genes accounts for a moving torus of gene expression that sweeps concentrically across the vegetal domain of the sea urchin embryo. Here we confirm by mutation the inputs into the blimp1cis-regulatory module predicted by network analysis. Its es...

    journal_title:Developmental biology

    pub_type: 杂志文章

    doi:10.1016/j.ydbio.2007.10.042

    authors: Smith J,Kraemer E,Liu H,Theodoris C,Davidson E

    更新日期:2008-01-15 00:00:00

  • Competition for factors and cellular resources as a principle of pattern formation in Hydra. II. Assistance of foot formation by heads and buds and a new model of pattern control.

    abstract::In Hydra long-range interactions between head, bud, and foot formation take place in addition to short-range interactions which are recognized as induction phenomena, occurring when transplants are placed into an environment of disparate positional value. Here the long-range promotion of foot formation is analyzed. Th...

    journal_title:Developmental biology

    pub_type: 杂志文章

    doi:10.1006/dbio.1995.1015

    authors: Müller WA

    更新日期:1995-01-01 00:00:00

  • CDX4 and retinoic acid interact to position the hindbrain-spinal cord transition.

    abstract::The sub-division of the posterior-most territory of the neural plate results in the formation of two distinct neural structures, the hindbrain and the spinal cord. Although many of the molecular signals regulating the development of these individual structures have been elucidated, the mechanisms involved in delineati...

    journal_title:Developmental biology

    pub_type: 杂志文章

    doi:10.1016/j.ydbio.2015.12.025

    authors: Chang J,Skromne I,Ho RK

    更新日期:2016-02-15 00:00:00

  • Formation of the dorsal root ganglia in the avian embryo: segmental origin and migratory behavior of neural crest progenitor cells.

    abstract::The segmental origin and migratory pattern of neural crest cells at the trunk level of avian embryos was studied, with special emphasis on the formation of the dorsal root ganglia (DRG) which organize in the anterior half of each somite. Neural crest cells were visualized using the quail-chick marker and HNK-1 immunof...

    journal_title:Developmental biology

    pub_type: 杂志文章

    doi:10.1016/0012-1606(87)90236-3

    authors: Teillet MA,Kalcheim C,Le Douarin NM

    更新日期:1987-04-01 00:00:00

  • Tudor-related proteins TDRD1/MTR-1, TDRD6 and TDRD7/TRAP: domain composition, intracellular localization, and function in male germ cells in mice.

    abstract::The germ-line cells of many animals possess a characteristic cytoplasmic structure termed nuage or germinal granules. In mice, nuage that is prominent in postnatal male germ cells is also called intermitochondrial cement or chromatoid bodies. TDRD1/MTR-1, which contains Tudor domain repeats, is a specific component of...

    journal_title:Developmental biology

    pub_type: 杂志文章

    doi:10.1016/j.ydbio.2006.10.046

    authors: Hosokawa M,Shoji M,Kitamura K,Tanaka T,Noce T,Chuma S,Nakatsuji N

    更新日期:2007-01-01 00:00:00

  • Dicer inactivation in osteoprogenitor cells compromises fetal survival and bone formation, while excision in differentiated osteoblasts increases bone mass in the adult mouse.

    abstract::MicroRNA attenuation of protein translation has emerged as an important regulator of mesenchymal cell differentiation into the osteoblast lineage. A compelling question is the extent to which miR biogenesis is obligatory for bone formation. Here we show conditional deletion of the Dicer enzyme in osteoprogenitors by C...

    journal_title:Developmental biology

    pub_type: 杂志文章

    doi:10.1016/j.ydbio.2010.01.008

    authors: Gaur T,Hussain S,Mudhasani R,Parulkar I,Colby JL,Frederick D,Kream BE,van Wijnen AJ,Stein JL,Stein GS,Jones SN,Lian JB

    更新日期:2010-04-01 00:00:00

  • Differential binding of oocyte-type and somatic-type 5S rRNA to TFIIIA and ribosomal protein L5 in Xenopus oocytes: specialization for storage versus mobilization.

    abstract::We studied the pathway of 5S ribosomal RNA (rRNA) during oogenesis in Xenopus from its storage in the cytoplasm to incorporation into ribosomes in the nucleus. Ribonucleoprotein particle (RNP) assembly assays reveal striking differences in the behavior of oocyte-type and somatic-type 5S rRNA after microinjection into ...

    journal_title:Developmental biology

    pub_type: 杂志文章

    doi:10.1006/dbio.1995.1080

    authors: Allison LA,North MT,Neville LA

    更新日期:1995-04-01 00:00:00

  • The patterns on chondrogenesis of cells from facial primordia of chick embryos in micromass culture.

    abstract::Chondrogenesis of mesenchymal cells from the frontonasal mass, mandibles and maxillae of stage-24 chick embryos has been investigated in micromass (high-density) cultures. Distinct differences in the amount and pattern of cartilage differentiation are found. In cultures of frontonasal mass cells, a central sheet of ca...

    journal_title:Developmental biology

    pub_type: 杂志文章

    doi:10.1016/0012-1606(86)90349-0

    authors: Wedden SE,Lewin-Smith MR,Tickle C

    更新日期:1986-09-01 00:00:00

  • Analyses of oviductal pars recta-induced fertilizability of coelomic eggs in Xenopus laevis.

    abstract::The acquisition of fertilizability in coelomic eggs of Xenopus laevis has been shown to be correlated with the physical, biochemical, and ultrastructural alterations of the egg envelope [coelomic envelope (CE)] induced during the passage of eggs through the pars recta portion of the oviduct. However, no direct evidenc...

    journal_title:Developmental biology

    pub_type: 杂志文章

    doi:10.1006/dbio.1999.9285

    authors: Katagiri C,Yoshizaki N,Kotani M,Kubo H

    更新日期:1999-06-15 00:00:00

  • Abnormal keratinization in the pupoid fetus (pf/pf) mutant mouse epidermis.

    abstract::During its development the epidermis of the pf/pf mutant mouse is invaded by cells from the underlying dermis. These invading cells establish a network of cells including fibroblasts, endothelial cells, and nerve fibers, throughout the epidermis. Subsequent to these events the keratohyalin protein, filaggrin, is drast...

    journal_title:Developmental biology

    pub_type: 杂志文章

    doi:10.1016/0012-1606(84)90194-5

    authors: Fisher C,Dale BA,Kollar EJ

    更新日期:1984-04-01 00:00:00

  • Quantitative change in fibronectin in cultured müllerian mesenchymal cells in response to diethylstilbestrol and müllerian-inhibiting substance.

    abstract::I report on the synthesis of fibronectin in the developing chick Müllerian duct mesenchymal cells. Before the differentiation of female chick Müllerian duct, the amount of fibronectin in the cells of the right duct is 44% lower than in the left duct. While after differentiation, the amount of fibronectin in the right ...

    journal_title:Developmental biology

    pub_type: 杂志文章

    doi:10.1016/0012-1606(90)90047-m

    authors: Teng CS

    更新日期:1990-07-01 00:00:00

  • Conservation as well as divergence in Mcidas function underlies the differentiation of multiciliated cells in vertebrates.

    abstract::Multiciliated cells (MCCs) differentiate hundreds of motile cilia that beat to drive fluid movement over various kinds of epithelia. In Xenopus, mice and human, the coiled-coil containing protein Mcidas (Mci) has been shown to be a key transcriptional regulator of MCC differentiation. We have examined Mci function in ...

    journal_title:Developmental biology

    pub_type: 杂志文章

    doi:10.1016/j.ydbio.2020.07.005

    authors: Zhou F,Rayamajhi D,Ravi V,Narasimhan V,Chong YL,Lu H,Venkatesh B,Roy S

    更新日期:2020-09-15 00:00:00

  • Expression of the differentiated phenotype by epithelial cells in vitro is regulated by both biochemistry and mechanics of the substratum.

    abstract::In this paper I sought to determine how the expression of differentiated traits of chick retinal pigmented epithelial (RPE) cells in vitro can be modulated by varying both the biochemical and the spatial complexity, and the mechanical properties, of the growth substratum. I have used glass derivatized with proteins of...

    journal_title:Developmental biology

    pub_type: 杂志文章

    doi:10.1016/s0012-1606(89)80001-6

    authors: Opas M

    更新日期:1989-02-01 00:00:00

  • Changes in intercellular junctions. II. Modulation in embryonic chick liver in vitro by cytosine arabinoside and dexamethasone.

    abstract::We have used an in vitro model to investigate the relationship between cell proliferation, cell maturation, and intercellular junctional changes that are seen during normal liver development. Chick liver fragments of embryonic stages 21, 28, and 39 were grown in organ culture in Medium 199 with 10% bovine serum albumi...

    journal_title:Developmental biology

    pub_type: 杂志文章

    doi:10.1016/0012-1606(83)90265-8

    authors: Meyer RA,Overton J

    更新日期:1983-09-01 00:00:00

  • Hox transcription factor Antp regulates sericin-1 gene expression in the terminal differentiated silk gland of Bombyx mori.

    abstract::Hox genes are well-known master regulators in developmental morphogenesis along the anteroposterior axis of animals. However, the molecular mechanisms by which Hox proteins regulate their target genes and determine cell fates are not fully understood. The silk gland of Bombyx mori is a tubular tissue divided into seve...

    journal_title:Developmental biology

    pub_type: 杂志文章

    doi:10.1016/j.ydbio.2013.12.002

    authors: Kimoto M,Tsubota T,Uchino K,Sezutsu H,Takiya S

    更新日期:2014-02-01 00:00:00

  • Glypican-3 modulates BMP- and FGF-mediated effects during renal branching morphogenesis.

    abstract::The kidney of the Gpc3-/ mouse, a novel model of human renal dysplasia, is characterized by selective degeneration of medullary collecting ducts preceded by enhanced cell proliferation and overgrowth during branching morphogenesis. Here, we identify cellular and molecular mechanisms underlying this renal dysplasia. Gl...

    journal_title:Developmental biology

    pub_type: 杂志文章

    doi:10.1006/dbio.2000.0127

    authors: Grisaru S,Cano-Gauci D,Tee J,Filmus J,Rosenblum ND

    更新日期:2001-03-01 00:00:00

  • Yolk proteins of Caenorhabditis elegans.

    abstract::A group of proteins judged on several criteria to be yolk proteins have been isolated from a homogenate of the nematode Caenorhabditis elegans. Comparison of partial proteolysis fragments indicates that the two bands of a 170,000-dalton doublet (yp170) are closely related; bands observed at 115,000 daltons (yp115) and...

    journal_title:Developmental biology

    pub_type: 杂志文章

    doi:10.1016/0012-1606(83)90321-4

    authors: Sharrock WJ

    更新日期:1983-03-01 00:00:00

  • Inhibition by dibutyryl cyclic AMP of the transition to metaphase of mouse oocyte nuclei and its reversal by cell fusion to metaphase oocytes.

    abstract::Mouse oocytes at metaphase I of meiotic maturation were treated with puromycin, which caused the condensed chromosomes to become decondensed to form an interphase nucleus. The chromosomes returned to a metaphase state 6.3 hr after the oocytes were transferred to puromycin-free medium [H. J. Clarke and Y. Masui (1983) ...

    journal_title:Developmental biology

    pub_type: 杂志文章

    doi:10.1016/0012-1606(85)90006-5

    authors: Clarke HJ,Masui Y

    更新日期:1985-03-01 00:00:00

  • ADAM 13: a novel ADAM expressed in somitic mesoderm and neural crest cells during Xenopus laevis development.

    abstract::Embryonic development involves a series of cell adhesive interactions that provide mechanical and instructive information required for morphogenesis. The ADAMs family of membrane-anchored proteins, containing a disintegrin and metalloprotease domain, is well suited for participating in such developmental events. They ...

    journal_title:Developmental biology

    pub_type: 杂志文章

    doi:10.1006/dbio.1996.8458

    authors: Alfandari D,Wolfsberg TG,White JM,DeSimone DW

    更新日期:1997-02-15 00:00:00

  • Dissecting Drosophila embryonic brain development using photoactivated gene expression.

    abstract::The Drosophila brain is generated by a complex series of morphogenetic movements. To better understand brain development and to provide a guide for experimental manipulation of brain progenitors, we created a fate map using photoactivated gene expression to mark cells originating within specific mitotic domains and ti...

    journal_title:Developmental biology

    pub_type: 杂志文章

    doi:10.1016/s0012-1606(03)00220-3

    authors: Robertson K,Mergliano J,Minden JS

    更新日期:2003-08-01 00:00:00

  • Decoupling brain from nerve cord development in the annelid Capitella teleta: Insights into the evolution of nervous systems.

    abstract::In the deuterostomes and ecdysozoans that have been studied (e.g. chordates and insects), neural fate specification relies on signaling from surrounding cells. However, very little is known about mechanisms of neural specification in the third major bilaterian clade, spiralians. Using blastomere isolation in the annel...

    journal_title:Developmental biology

    pub_type: 杂志文章

    doi:10.1016/j.ydbio.2017.09.022

    authors: Carrillo-Baltodano AM,Meyer NP

    更新日期:2017-11-15 00:00:00

  • Foxe3 is required for morphogenesis and differentiation of the anterior segment of the eye and is sensitive to Pax6 gene dosage.

    abstract::The dysgenetic lens (dyl) mouse mutant has mutations in Foxe3, which inactivate DNA binding by the encoded forkhead transcription factor. Here we confirm, by targeted inactivation, that Foxe3 mutations are responsible for the dyl phenotype, which include loss of lens epithelium; a small, cataractic lens; and failure o...

    journal_title:Developmental biology

    pub_type: 杂志文章

    doi:10.1016/j.ydbio.2006.09.021

    authors: Blixt A,Landgren H,Johansson BR,Carlsson P

    更新日期:2007-02-01 00:00:00

  • The phosphoprotein protein PEA-15 inhibits Fas- but increases TNF-R1-mediated caspase-8 activity and apoptosis.

    abstract::We have characterized a phosphoprotein protein with a death effector domain that has a novel bifunctional role in programmed cell death. The 15-kDa phosphoprotein enriched in astrocytes (PEA-15) inhibits Fas-mediated apoptosis and increases tumor necrosis factor receptor-1 (TNF-R1)-mediated apoptosis in the same cell ...

    journal_title:Developmental biology

    pub_type: 杂志文章

    doi:10.1006/dbio.1999.9510

    authors: Estellés A,Charlton CA,Blau HM

    更新日期:1999-12-01 00:00:00

  • Ecdysone regulates morphogenesis and function of Malpighian tubules in Drosophila melanogaster through EcR-B2 isoform.

    abstract::Malpighian tubules are the osmoregulatory and detoxifying organs of Drosophila and its proper development is critical for the survival of the organism. They are made up of two major cell types, the ectodermal principal cells and mesodermal stellate cells. The principal and stellate cells are structurally and physiolog...

    journal_title:Developmental biology

    pub_type: 杂志文章

    doi:10.1016/j.ydbio.2014.11.003

    authors: Gautam NK,Verma P,Tapadia MG

    更新日期:2015-02-15 00:00:00

  • Id4 is required for the correct timing of neural differentiation.

    abstract::Complex intrinsic and extrinsic mechanisms determine neural cell fate during development of the nervous system. Using Id4 deficient mice, we show that Id4 is required for normal development of the central nervous system (CNS), timing neural differentiation in the developing forebrain. In the absence of Id4, the ventri...

    journal_title:Developmental biology

    pub_type: 杂志文章

    doi:10.1016/j.ydbio.2005.02.001

    authors: Bedford L,Walker R,Kondo T,van Crüchten I,King ER,Sablitzky F

    更新日期:2005-04-15 00:00:00

  • Roles of the Wnt effector POP-1/TCF in the C. elegans endomesoderm specification gene network.

    abstract::In C. elegans the 4-cell stage blastomere EMS is an endomesodermal precursor. Its anterior daughter, MS, makes primarily mesodermal cells, while its posterior daughter E generates the entire intestine. The gene regulatory network underlying specification of MS and E has been the subject of study for more than 15 years...

    journal_title:Developmental biology

    pub_type: 杂志文章

    doi:10.1016/j.ydbio.2009.09.042

    authors: Owraghi M,Broitman-Maduro G,Luu T,Roberson H,Maduro MF

    更新日期:2010-04-15 00:00:00

  • Conditional Aurora A deficiency differentially affects early mouse embryo patterning.

    abstract::Aurora A is a mitotic kinase essential for cell proliferation. In mice, ablation of Aurora A results in mitotic arrest and pre-implantation lethality, preventing studies at later stages of development. Here we report the effects of Aurora A ablation on embryo patterning at early post-implantation stages. Inactivation ...

    journal_title:Developmental biology

    pub_type: 杂志文章

    doi:10.1016/j.ydbio.2012.08.010

    authors: Yoon Y,Cowley DO,Gallant J,Jones SN,Van Dyke T,Rivera-Pérez JA

    更新日期:2012-11-01 00:00:00

  • Altered sensory projections in the chick hind limb following the early removal of motoneurons.

    abstract::Chick sensory neurons grow to their correct targets in the hindlimb from the outset during normal development and following various experimental manipulations. This may result not because sensory neurons respond to specific limb-derived cues, but because they interact in some way with motoneurons which are responsive ...

    journal_title:Developmental biology

    pub_type: 杂志文章

    doi:10.1016/0012-1606(86)90023-0

    authors: Landmesser L,Honig MG

    更新日期:1986-12-01 00:00:00

  • Effect of hydrocortisone on skin development in the chick embryo: ultrastructural, immunohistological, and biochemical analysis.

    abstract::The effect of hydrocortisone on the development of dorsal skin was analyzed in the chick embryo by (1) transmission electron microscopy, (2) indirect immunofluorescence histology of extracellular matrix components (collagen types I, III, and IV; fibronectin; and laminin), and (3) quantitative determination of collagen...

    journal_title:Developmental biology

    pub_type: 杂志文章

    doi:10.1016/0012-1606(84)90056-3

    authors: Démarchez M,Mauger A,Herbage D,Sengel P

    更新日期:1984-11-01 00:00:00

  • Regulation of Hex gene expression and initial stages of avian hepatogenesis by Bmp and Fgf signaling.

    abstract::The vertebrate liver and heart arise from adjacent cell layers in the anterior lateral (AL) endoderm and mesoderm of late gastrula embryos, and the earliest stages of liver and heart development are interrelated through reciprocal tissue interactions. Although classical embryological studies performed several decades ...

    journal_title:Developmental biology

    pub_type: 杂志文章

    doi:10.1016/j.ydbio.2004.01.019

    authors: Zhang W,Yatskievych TA,Baker RK,Antin PB

    更新日期:2004-04-15 00:00:00