Abstract：
:Biologists have long recognized that dramatic bending of a cell sheet may be driven by even modest shrinking of the apical sides of cells. Cell shape changes and tissue movements like these are at the core of many of the morphogenetic movements that shape animal form during development, driving processes such as gastrulation, tube formation, and neurulation. The mechanisms of such cell shape changes must integrate developmental patterning information in order to spatially and temporally control force production-issues that touch on fundamental aspects of both cell and developmental biology and on birth defects research. How does developmental patterning regulate force-producing mechanisms, and what roles do such mechanisms play in development? Work on apical constriction from multiple systems including Drosophila, Caenorhabditis elegans, sea urchin, Xenopus, chick, and mouse has begun to illuminate these issues. Here, we review this effort to explore the diversity of mechanisms of apical constriction, the diversity of roles that apical constriction plays in development, and the common themes that emerge from comparing systems.
journal_name
Dev Bioljournal_title
Developmental biologyauthors
Sawyer JM,Harrell JR,Shemer G,Sullivan-Brown J,Roh-Johnson M,Goldstein Bdoi
10.1016/j.ydbio.2009.09.009subject
Has Abstractpub_date
2010-05-01 00:00:00pages
5-19issue
1eissn
0012-1606issn
1095-564Xpii
S0012-1606(09)01178-6journal_volume
341pub_type
杂志文章,评审abstract：:There is a natural curiosity about how organisms give rise to offspring like themselves through a series of reproducible developmental events and how, once mature, these offspring mate and continue the process giving rise the next generation. In the mid-1800s investigators started using gametes and embryos to explore ...
journal_title：Developmental biology
pub_type： 历史文章,杂志文章
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abstract：:Cloning and sequencing of Tripneustes gratilla genomic DNA and cDNA encoding a developmentally regulated, embryonic messenger RNA, referred to as Tg616, revealed an actin-encoding gene orthologous to the CyI actin gene described from Strongylocentrotus purpuratus. Tg616 and SpCyI share: (1) 150 nucleotides of highly c...
journal_title：Developmental biology
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journal_title：Developmental biology
pub_type： 杂志文章
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pub_type： 杂志文章
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更新日期：2003-12-01 00:00:00
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