Studies on the differentiation of egg envelopes. I. The starfish, Astropecten aurantiacus.


:We have studied the differentiation of the oocyte vitelline coat (VC) and jelly coat (JC) of the starfish, Astropecten aurantiacus. The precursor material of both envelopes is secreted by the oocyte while the follicle cells do not appear to participate in the secretory process. The first indication of differentiation of the VC is the deposition of a fine fibrillar material between the microvilli which emerge from the oocyte surface. External to this, a more loosely organized material becomes the precursor of the JC. At this time both layers are periodic acid-Schiff (PAS)-positive. In a later stage, the material between the microvilli acquires a more compact organization, looses its PAS-positivity while acquiring fucose binding protein (FBP) affinity. On the contrary, the JC remains PAS-positive and FBP-negative. In the full grown oocytes the VC is made up of densely packed fibrils oriented tangentially to the oocyte surface and is tightly bound to the microvilli. The observations are discussed in connection with the problem of the role of the egg envelopes in sperm-egg recognition and in the induction of the acrosome reaction.


Dev Biol


Developmental biology


Santella L,Monroy A,Rosati F




Has Abstract


1983-10-01 00:00:00














  • Growth factors, mitogens, cytokines, and bone morphogenetic protein in induced chondrogenesis in tissue culture.

    abstract::Connective tissue outgrowths of neonatal muscle onto a substratum of bone matrix differentiate into cartilage in response to a bone morphogenetic protein (BMP). The BMP can be separated from bone matrix by extraction with 4 M guanidine hydrochloride (GuHCl) or degraded in situ by endogenous proteolytic enzymes to deac...

    journal_title:Developmental biology

    pub_type: 杂志文章


    authors: Kawamura M,Urist MR

    更新日期:1988-12-01 00:00:00

  • Regulation of broad by the Notch pathway affects timing of follicle cell development.

    abstract::During Drosophila oogenesis, activation of Notch signaling in the follicular epithelium (FE) around stage 6 of oogenesis is essential for entry into the endocycle and a series of other changes such as cell differentiation and migration of subsets of the follicle cells. Notch induces the expression of zinc finger prote...

    journal_title:Developmental biology

    pub_type: 杂志文章


    authors: Jia D,Tamori Y,Pyrowolakis G,Deng WM

    更新日期:2014-08-01 00:00:00

  • Cavitation in the mouse preimplantation embryo: Na/K-ATPase and the origin of nascent blastocoele fluid.

    abstract::This study tested the proposition that Na/K-ATPase activity could be involved in the morphogenetic aspects of mouse blastocyst formation by facilitating the localization of certain organelles to apposed borders, the production of nascent blastocoele fluid, and cavitation. It was assumed that such Na/K-ATPase activity ...

    journal_title:Developmental biology

    pub_type: 杂志文章


    authors: Wiley LM

    更新日期:1984-10-01 00:00:00

  • Cell sorting and chondrogenic aggregate formation in micromass culture.

    abstract::A fundamental feature of cartilage differentiation in the developing limb is the formation of a prechondrogenic cell condensation. An apparently similar process of prechondrogenic cell aggregation occurs in micromass cultures of limb bud mesenchyme with the formation of cellular aggregates which often differentiate in...

    journal_title:Developmental biology

    pub_type: 杂志文章


    authors: Cottrill CP,Archer CW,Wolpert L

    更新日期:1987-08-01 00:00:00

  • Regulation of specific developmental fates of larval- and adult-type muscles during metamorphosis of the frog Xenopus.

    abstract::During anuran metamorphosis, larval-type myotubes in both trunk and tail are removed by apoptosis, and only trunk muscles are replaced by newly formed adult-type myotubes. In the present study, we clarified the regulatory mechanisms for specific developmental fates of adult and larval muscles. Two distinct (adult and ...

    journal_title:Developmental biology

    pub_type: 杂志文章


    authors: Shimizu-Nishikawa K,Shibota Y,Takei A,Kuroda M,Nishikawa A

    更新日期:2002-11-01 00:00:00

  • Early mammillary pouch specification in the course of prechordal ventralization of the forebrain tegmentum.

    abstract::The mammillary body, a ventral specialization of the caudal hypothalamus, lies close to the transition between epichordal and prechordal parts of the forebrain (Puelles and Rubenstein, 2003). This report examines its presumed causal connection with either prechordal or notochordal mesodermal induction, as well as the ...

    journal_title:Developmental biology

    pub_type: 杂志文章


    authors: García-Calero E,Fernández-Garre P,Martínez S,Puelles L

    更新日期:2008-08-15 00:00:00

  • The enzymatic activity of Drosophila AWD/NDP kinase is necessary but not sufficient for its biological function.

    abstract::The Drosophila abnormal wing discs (awd) gene encodes the subunit of a protein that has nucleoside diphosphate kinase (NDP kinase) activity. Null mutations of the awd gene cause lethality after puparium formation. Larvae homozygous for such mutations have small imaginal discs, lymph glands, and brain lobes. Neither th...

    journal_title:Developmental biology

    pub_type: 杂志文章


    authors: Xu J,Liu LZ,Deng XF,Timmons L,Hersperger E,Steeg PS,Veron M,Shearn A

    更新日期:1996-08-01 00:00:00

  • Sp5, a new member of the Sp1 family, is dynamically expressed during development and genetically interacts with Brachyury.

    abstract::We describe the identification, biochemical characterisation, and mutation of a novel mouse gene: Sp5. Sp5 encodes a protein having a C-terminal C(2)H(2) zinc finger domain closely related to that of the transcription factor Sp1. In vitro, DNA binding studies show that it binds to the GC box, a DNA motif present in th...

    journal_title:Developmental biology

    pub_type: 杂志文章


    authors: Harrison SM,Houzelstein D,Dunwoodie SL,Beddington RS

    更新日期:2000-11-15 00:00:00

  • The basal position of nuclei is one pre-requisite for asymmetric cell divisions in the early mouse embryo.

    abstract::The early mouse embryo undertakes two types of cell division: symmetric that gives rise to the trophectoderm and then placenta or asymmetric that gives rise to inner cells that generate the embryo proper. Although cell division orientation is important, the mechanism regulating it has remained unclear. Here, we identi...

    journal_title:Developmental biology

    pub_type: 杂志文章


    authors: Ajduk A,Biswas Shivhare S,Zernicka-Goetz M

    更新日期:2014-08-15 00:00:00

  • Cell specific loss of polarity-inducing ability by later stage mouse preimplantation embryos.

    abstract::The individual blastomeres of the preimplantation mouse embryo become polarized during the 8-cell stage. Microvilli become restricted to the free surface of the embryo and this region of the membrane shows increased labeling with FITC-Con A and trinitrobenzenesulfonate (TNBS). Previous studies have shown that this pol...

    journal_title:Developmental biology

    pub_type: 杂志文章


    authors: Adler RR,Ziomek CA

    更新日期:1986-04-01 00:00:00

  • Human cytotrophoblasts promote endothelial survival and vascular remodeling through secretion of Ang2, PlGF, and VEGF-C.

    abstract::Cytotrophoblasts are specialized epithelial cells of the human placenta that differentiate to acquire tumor-like properties that allow them to invade the uterus. Concurrently, they develop endothelial-like characteristics. This transformation allows cytotrophoblasts to replace the maternal cells that line uterine vess...

    journal_title:Developmental biology

    pub_type: 杂志文章


    authors: Zhou Y,Bellingard V,Feng KT,McMaster M,Fisher SJ

    更新日期:2003-11-01 00:00:00

  • Specific induction of apoptosis in P19 embryonal carcinoma cells by retinoic acid and BMP2 or BMP4.

    abstract::Retinoic acid (RA) affects the response of many cells to growth factors, including the bone morphogenetic proteins (BMPs). The BMPs are members of the TGF-beta, family of growth factors, originally identified by their bone-inducing activities. Their widespread expression suggests many roles other than that in osteogen...

    journal_title:Developmental biology

    pub_type: 杂志文章


    authors: Glozak MA,Rogers MB

    更新日期:1996-11-01 00:00:00

  • Ecdysone regulates morphogenesis and function of Malpighian tubules in Drosophila melanogaster through EcR-B2 isoform.

    abstract::Malpighian tubules are the osmoregulatory and detoxifying organs of Drosophila and its proper development is critical for the survival of the organism. They are made up of two major cell types, the ectodermal principal cells and mesodermal stellate cells. The principal and stellate cells are structurally and physiolog...

    journal_title:Developmental biology

    pub_type: 杂志文章


    authors: Gautam NK,Verma P,Tapadia MG

    更新日期:2015-02-15 00:00:00

  • Two temporal functions of Glass: Ommatidium patterning and photoreceptor differentiation.

    abstract::Much progress has been made in elucidating the molecular networks required for specifying retinal cells, including photoreceptors, but the downstream mechanisms that maintain identity and regulate differentiation remain poorly understood. Here, we report that the transcription factor Glass has a dual role in establish...

    journal_title:Developmental biology

    pub_type: 杂志文章


    authors: Liang X,Mahato S,Hemmerich C,Zelhof AC

    更新日期:2016-06-01 00:00:00

  • t haplotypes in the mouse compromise sperm flagellar function.

    abstract::The t haplotypes are variant forms of the proximal portion of chromosome 17 in the mouse. The t haplotypes alter spermatogenesis and many also contain lethal factors. Although the lethal factors vary between t haplotypes, all t haplotypes have the same effect on sperm, that of altering sperm function in fertilization....

    journal_title:Developmental biology

    pub_type: 杂志文章


    authors: Olds-Clarke P,Johnson LR

    更新日期:1993-01-01 00:00:00

  • BMP7 inhibits branching morphogenesis in the prostate gland and interferes with Notch signaling.

    abstract::The mouse prostate gland develops by branching morphogenesis from the urogenital epithelium and mesenchyme. Androgens and developmental factors, including FGF10 and SHH, promote prostate growth (Berman, D.M., Desai, N., Wang, X., Karhadkar, S.S., Reynon, M., Abate-Shen, C., Beachy, P.A., Shen, M.M., 2004. Roles for He...

    journal_title:Developmental biology

    pub_type: 杂志文章


    authors: Grishina IB,Kim SY,Ferrara C,Makarenkova HP,Walden PD

    更新日期:2005-12-15 00:00:00

  • Regulation of ascorbic acid concentration in embryonic chick brain.

    abstract::The relationship between ascorbic acid concentration and cellular transport mechanisms was studied in chicken embryos (Gallus gallus domesticus). Unincubated (Day 0) fertile eggs did not contain detectable levels of ascorbic acid as assayed by high performance liquid chromatography with electrochemical detection. Howe...

    journal_title:Developmental biology

    pub_type: 杂志文章


    authors: Wilson JX

    更新日期:1990-06-01 00:00:00

  • Midline-derived Shh regulates mesonephric tubule formation through the paraxial mesoderm.

    abstract::During organogenesis, Sonic hedgehog (Shh) possesses dual functions: Shh emanating from midline structures regulates the positioning of bilateral structures at early stages, whereas organ-specific Shh locally regulates organ morphogenesis at later stages. The mesonephros is a transient embryonic kidney in amniote, whe...

    journal_title:Developmental biology

    pub_type: 杂志文章


    authors: Murashima A,Akita H,Okazawa M,Kishigami S,Nakagata N,Nishinakamura R,Yamada G

    更新日期:2014-02-01 00:00:00

  • Cadherin-11 expressed in association with mesenchymal morphogenesis in the head, somite, and limb bud of early mouse embryos.

    abstract::Cadherin-11 (cad-11) is a novel member of the cadherin family of cell adhesion molecules, having recently been identified by means of the polymerase chain reaction. To study the function and expression of this molecule, we cloned mouse, cad-11 cDNA. Transfection of L cells with cDNA led them to acquire a typical cadhe...

    journal_title:Developmental biology

    pub_type: 杂志文章


    authors: Kimura Y,Matsunami H,Inoue T,Shimamura K,Uchida N,Ueno T,Miyazaki T,Takeichi M

    更新日期:1995-05-01 00:00:00

  • Spermatogonia-dependent expression of testicular genes in mice.

    abstract::Spermatogenesis is initiated by the interaction of germ cells and somatic cells in seminiferous tubules. We used cDNA microarrays and representational difference analysis to identify genes that are expressed in the testis of the jsd/jsd mutant mouse, which contains only type A spermatogonial germ cells and Sertoli cel...

    journal_title:Developmental biology

    pub_type: 杂志文章


    authors: Tanaka K,Tamura H,Tanaka H,Katoh M,Futamata Y,Seki N,Nishimune Y,Hara T

    更新日期:2002-06-15 00:00:00

  • Method for disarranging the pigment pattern of zebrafish by optogenetics.

    abstract::To investigate the spatiotemporal dynamics of skin pattern formation, we developed a simple method for artificially disarranging the placement of all three pigment cell types in the body trunk of zebrafish (Danio rerio). We generated transgenic fish with melanophores that ectopically expressed a variant of channelrhod...

    journal_title:Developmental biology

    pub_type: 杂志文章


    authors: Aramaki T,Kondo S

    更新日期:2020-04-01 00:00:00

  • Coordinate and noncoordinate regulation of synaptic vesicle protein genes during embryonic development.

    abstract::Because the formation of a mature nerve terminal requires the accumulation of large quantities of synaptic vesicles, the expression of synaptic vesicle proteins would be expected to correlate with synaptogenesis. However, previous studies have provided conflicting evidence on this point. We have examined the developme...

    journal_title:Developmental biology

    pub_type: 杂志文章


    authors: Lou X,Bixby JL

    更新日期:1993-09-01 00:00:00

  • Topographic targeting and pathfinding errors of retinal axons following overexpression of ephrinA ligands on retinal ganglion cell axons.

    abstract::In the retinotectal projection, the Eph receptor tyrosine kinase ligands ephrinA2 and ephrinA5 are differentially expressed not only in the tectum, but also in a high-nasal-to-low-temporal pattern in the retina. Recently, we have shown that retrovirally driven overexpression of ephrinA2 on retinal axons leads to topog...

    journal_title:Developmental biology

    pub_type: 杂志文章


    authors: Dütting D,Handwerker C,Drescher U

    更新日期:1999-12-01 00:00:00

  • A MAPK pathway is involved in the control of mitosis after fertilization of the sea urchin egg.

    abstract::Activation and role of mitogen-activated protein (MAP) kinase (MAPK) during mitosis are still matters of controversy in early embryos. We report here that an ERK-like protein is present and highly phosphorylated in unfertilized sea urchin eggs. This MAPK becomes dephosphorylated after fertilization and a small pool of...

    journal_title:Developmental biology

    pub_type: 杂志文章


    authors: Zhang WL,Huitorel P,Glass R,Fernandez-Serra M,Arnone MI,Chiri S,Picard A,Ciapa B

    更新日期:2005-06-01 00:00:00

  • Scheduled and unscheduled DNA synthesis during development in conjugating Tetrahymena.

    abstract::Autoradiography has been used to confirm and to extend previous microspectrophotometric studies (Doerder and DeBault, 1975) on the timing of DNA synthesis during conjugation in Tetrahymena thermophila. The majority of DNA synthesis occurs at the expected periods preceding gamete formation and the two postzygotic divis...

    journal_title:Developmental biology

    pub_type: 杂志文章


    authors: Allis CD,Colavito-Shepanski M,Gorovsky MA

    更新日期:1987-12-01 00:00:00

  • Quantitative analysis of cyclic AMP waves mediating aggregation in Dictyostelium discoideum.

    abstract::We have previously reported the detection of cAMP waves within monolayers of aggregating Dictyostelium discoideum cells (K. J. Tomchik and P.N. Devreotes, 1981, Science 212, 443-446). The computer-assisted analysis presented here of the fluorographic images of the cAMP waves reveals (1) all the waves have a consistent...

    journal_title:Developmental biology

    pub_type: 杂志文章


    authors: Devreotes PN,Potel MJ,MacKay SA

    更新日期:1983-04-01 00:00:00

  • Translational profiling of retinal ganglion cell optic nerve regeneration in Xenopus laevis.

    abstract::Unlike adult mammals, adult frogs regrow their optic nerve following a crush injury, making Xenopus laevis a compelling model for studying the molecular mechanisms that underlie neuronal regeneration. Using Translational Ribosome Affinity Purification (TRAP), a method to isolate ribosome-associated mRNAs from a target...

    journal_title:Developmental biology

    pub_type: 杂志文章


    authors: Whitworth GB,Misaghi BC,Rosenthal DM,Mills EA,Heinen DJ,Watson AH,Ives CW,Ali SH,Bezold K,Marsh-Armstrong N,Watson FL

    更新日期:2017-06-15 00:00:00

  • Both myoblast lineage and innervation determine fiber type and are required for expression of the slow myosin heavy chain 2 gene.

    abstract::Skeletal muscle fibers express members of the myosin heavy chain (MyHC) gene family in a fiber-type-specific manner. In avian skeletal muscle it is the expression of the slow MyHC isoforms that most clearly distinguishes slow- from fast-contracting fiber types. Two hypotheses have been proposed to explain fiber-type-s...

    journal_title:Developmental biology

    pub_type: 杂志文章


    authors: DiMario JX,Stockdale FE

    更新日期:1997-08-01 00:00:00

  • Migration and differentiation potential of stem cells in the cnidarian Hydractinia analysed in eGFP-transgenic animals and chimeras.

    abstract::To analyse cell migration and the differentiation potential of migratory stem cells in Hydractinia, we generated animals with an eGFP reporter gene stably expressed and transmitted via the germline. The transgene was placed under the control of two different actin promoters and the promoter of elongation factor-1α. On...

    journal_title:Developmental biology

    pub_type: 杂志文章


    authors: Künzel T,Heiermann R,Frank U,Müller W,Tilmann W,Bause M,Nonn A,Helling M,Schwarz RS,Plickert G

    更新日期:2010-12-01 00:00:00

  • Development of a muscle actin specified by maternal and zygotic mRNA in ascidian embryos.

    abstract::In this investigation, we characterize the embryonic and adult actins and describe the embryonic expression of a muscle actin in the ascidian Styela. Two-dimensional polyacrylamide gel electrophoresis showed that embryos, tadpole larvae, and adult organs contain three major and two minor isoforms of actin. Two of the ...

    journal_title:Developmental biology

    pub_type: 杂志文章


    authors: Tomlinson CR,Bates WR,Jeffery WR

    更新日期:1987-10-01 00:00:00