The impact of surgery for oral cancer on quality of life as measured by the Medical Outcomes Short Form 36.

Abstract:

:Quality of life evaluation is an important measure of outcome following the treatment of head and neck cancer. The aim of this study was to evaluate the quality of life of patients undergoing primary surgery for oral and oropharyngeal squamous cell carcinoma. 50 consecutive patients with previously untreated oral cancer were assessed using two questionnaires, the Medical Outcomes Short Form 36 (SF-36) and University of Washington Head and Neck Questionnaire (UW-QOL) at four time intervals; pretreatment, and 3, 6, 12 months. At the time of presentation, patients with oral cancer scored lower than norms, particularly for physical role limitation, mental role limitation, and social functioning. At 3 months following surgery, there was a considerable deterioration in physical functioning, limitation of physical role, energy and general health perception. By 12 months postoperatively patients approached pretreatment scores. The SF-36 and UW-QOL provide outcome information suitable for international comparison.

journal_name

Oral Oncol

journal_title

Oral oncology

authors

Rogers SN,Humphris G,Lowe D,Brown JS,Vaughan ED

doi

10.1016/s1368-8375(97)00069-9

subject

Has Abstract

pub_date

1998-05-01 00:00:00

pages

171-9

issue

3

eissn

1368-8375

issn

1879-0593

pii

S1368-8375(97)00069-9

journal_volume

34

pub_type

临床试验,杂志文章
  • Risk of contralateral nodal failure following ipsilateral IMRT for node-positive tonsillar cancer.

    abstract:PURPOSE:To determine the risk of contralateral nodal failure following ipsilateral radiotherapy in a series of patients with node-positive tonsillar squamous cell carcinoma. METHODS:Retrospective review was used to identify 34 patients with well-lateralized node-positive tonsillar squamous cell carcinoma treated with ...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2017.10.010

    authors: Gottumukkala S,Pham NL,Sumer B,Myers L,Truelson J,Nedzi L,Khan S,Hughes R,Sher DJ

    更新日期:2017-12-01 00:00:00

  • Responses in patients receiving sequential paclitaxel post progression on PD1 inhibitors.

    abstract::This report describes highlights the dramatic responses seen in patients who were given paclitaxel post progression on immunotherapy. There are multiple mechanisms by which synergistic effects of immunotherapy and chemotherapy occur. Further prospective studies on chemotherapy and immunotherapy are eagerly awaited. ...

    journal_title:Oral oncology

    pub_type: 信件

    doi:10.1016/j.oraloncology.2018.03.011

    authors: Sukari A,Nagasaka M,Abdallah N

    更新日期:2018-05-01 00:00:00

  • Definitive chemoradiation for primary oral cavity carcinoma: A single institution experience.

    abstract:OBJECTIVES:While surgery with or without adjuvant radiation therapy (RT) is the standard of care for oral cavity cancer (OCC), a select group requires nonsurgical treatment. We provide a single-institution experience using definitive chemotherapy and RT for primary OCC. MATERIALS AND METHODS:We examined 73 patients wi...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2015.04.007

    authors: Scher ED,Romesser PB,Chen C,Ho F,Wuu Y,Sherman EJ,Fury MG,Wong RJ,McBride S,Lee NY,Riaz N

    更新日期:2015-07-01 00:00:00

  • Fractionated photodynamic therapy for a human oral squamous cell carcinoma xenograft.

    abstract::The aim of this study was to define the appropriate fractionation interval between photodynamic therapies (PDTs) for enhanced anti-tumour effects on human oral squamous cell carcinoma (HOSCC). Reoxygenation of HOSCC and the proliferative kinetics of the tumour cells following PDT exposure were evaluated in terms of im...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2005.10.006

    authors: Togashi H,Uehara M,Ikeda H,Inokuchi T

    更新日期:2006-05-01 00:00:00

  • Tube feeding during treatment for head and neck cancer - Adherence and patient reported barriers.

    abstract:OBJECTIVES:The main aim was to investigate the incidence of patient adherence to nutritional tube feeding recommendations in patients with head and neck cancer and to determine patient barriers to meeting tube feeding prescription. MATERIALS AND METHODS:This was an observational study from a randomised controlled tria...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2017.07.017

    authors: Brown T,Banks M,Hughes BGM,Lin C,Kenny L,Bauer J

    更新日期:2017-09-01 00:00:00

  • Recurrent FGFR1 amplification and high FGFR1 protein expression in oral squamous cell carcinoma (OSCC).

    abstract::Chromosomal aberrations are known to have an impact on the initiation and progression of oral squamous cell carcinoma (OSCC), but individual genes involved in OSCC pathogenesis are poorly described. To elucidate the molecular events underlying oral carcinogenesis, a set of primary OSCC were screened for distinct genet...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2006.01.005

    authors: Freier K,Schwaenen C,Sticht C,Flechtenmacher C,Mühling J,Hofele C,Radlwimmer B,Lichter P,Joos S

    更新日期:2007-01-01 00:00:00

  • Malignant melanoma of the oral cavity: diagnosis and treatment experience in a Mexican population.

    abstract::Oral malignant melanoma is uncommon, accounting for 1-8% of all malignant melanomas. All previous papers have reported small numbers of cases or have retrospectively reviewed case reports from the literature. The following case reports concern malignant melanoma of the oral cavity seen at the Instituto Nacional de Can...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/s1368-8375(99)00017-2

    authors: Lopez-Graniel CM,Ochoa-Carrillo FJ,Meneses-García A

    更新日期:1999-07-01 00:00:00

  • Hypermethylated ZNF582 and PAX1 are effective biomarkers for detection of oral dysplasia and oral cancer.

    abstract:OBJECTIVES:This study investigated whether the methylation of ZNF582, PAX1, SOX1, NKX6.1, and PTPRR genes in oral scrapings could be used to detect oral dysplasia and oral cancer and to predict oral cancer recurrence. MATERIALS AND METHODS:Oral scrapings were collected from 65 normal oral mucosa subjects, 107 oral pre...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2016.09.007

    authors: Cheng SJ,Chang CF,Lee JJ,Chen HM,Wang HJ,Liou YL,Yen C,Chiang CP

    更新日期:2016-11-01 00:00:00

  • Assessment of pleomorphic adenomas using MRI and dynamic contrast enhanced MRI.

    abstract::We evaluated magnetic resonance images (MRI) and the value of dynamic contrast enhanced MRI (DCE-MRI) of pleomorphic adenomas retrospectively. MRI was performed for 18 pleomorphic adenomas, including 11 cases with DCE-MRI. We obtained the following results on the MRI and DCE-MRI. (a). Pleomorphic adenomas showed a pre...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/s1368-8375(03)00040-x

    authors: Hisatomi M,Asaumi J,Yanagi Y,Konouchi H,Matsuzaki H,Honda Y,Kishi K

    更新日期:2003-09-01 00:00:00

  • ERCC1 plays an important role in predicting survival outcomes and treatment response for patients with HNSCC: a meta-analysis.

    abstract:BACKGROUND:Excision repair crosscomplementing-1 (ERCC1) has been reported to play a prognostic role and may indicate the treatment response in patients with head and neck squamous carcinoma (HNSCC). Nevertheless, the strength of evidence of ERCC1 predicting these two clinical outcomes are still controversial. METHODS:...

    journal_title:Oral oncology

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.oraloncology.2015.02.094

    authors: Xuelei M,Jingwen H,Wei D,Hongyu Z,Jing Z,Changle S,Lei L

    更新日期:2015-05-01 00:00:00

  • 'Cytology-on-a-chip' based sensors for monitoring of potentially malignant oral lesions.

    abstract:UNLABELLED:Despite significant advances in surgical procedures and treatment, long-term prognosis for patients with oral cancer remains poor, with survival rates among the lowest of major cancers. Better methods are desperately needed to identify potential malignancies early when treatments are more effective. OBJECTI...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2016.07.002

    authors: Abram TJ,Floriano PN,Christodoulides N,James R,Kerr AR,Thornhill MH,Redding SW,Vigneswaran N,Speight PM,Vick J,Murdoch C,Freeman C,Hegarty AM,D'Apice K,Phelan JA,Corby PM,Khouly I,Bouquot J,Demian NM,Weinstock YE,

    更新日期:2016-09-01 00:00:00

  • Confocal laser endomicroscopy for non-invasive head and neck cancer imaging: a comprehensive review.

    abstract::Histological assessment is an essential tool in the diagnosis and guidance of the treatment of various diseases, in particular cancer, of the head and neck. Recent major advances in optical imaging techniques have made it possible to acquire high-resolution in vivo images at the cellular scale. Confocal endomicroscopy...

    journal_title:Oral oncology

    pub_type: 杂志文章,评审

    doi:10.1016/j.oraloncology.2014.05.002

    authors: Abbaci M,Breuskin I,Casiraghi O,De Leeuw F,Ferchiou M,Temam S,Laplace-Builhé C

    更新日期:2014-08-01 00:00:00

  • Salivary gland carcinoma in Denmark 1990-2005: outcome and prognostic factors. Results of the Danish Head and Neck Cancer Group (DAHANCA).

    abstract::To describe outcome and prognostic factors in a national Danish series of patients treated for salivary gland carcinoma. From three Danish nation-wide registries and supplementary patient records, 871 patients diagnosed with primary major or minor salivary gland carcinoma in the period from 1990 to 2005 were identifie...

    journal_title:Oral oncology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.oraloncology.2011.09.005

    authors: Bjørndal K,Krogdahl A,Therkildsen MH,Overgaard J,Johansen J,Kristensen CA,Homøe P,Sørensen CH,Andersen E,Bundgaard T,Primdahl H,Lambertsen K,Andersen LJ,Godballe C

    更新日期:2012-02-01 00:00:00

  • Staging and IgA VCA titre in patients with nasopharyngeal carcinoma: changes over a 12-year period.

    abstract::The distributions of 2093 patients with nasopharyngeal carcinoma (NPC), by stage, over a 12-year-period did not show any evidence of a shift towards early stages despite growing awareness of this prevalent malignancy. The IgA VCA titre was determined for 1880 of these patients. The median titre increased from 40 in st...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/s1368-8375(98)00063-3

    authors: Ho S,Teo P,Kwan WH,Choi P,Tjong J,Johnson PJ

    更新日期:1998-11-01 00:00:00

  • Vascular priming enhances chemotherapeutic efficacy against head and neck cancer.

    abstract:PURPOSE:The need to improve chemotherapeutic efficacy against head and neck squamous cell carcinomas (HNSCC) is well recognized. In this study, we investigated the potential of targeting the established tumor vasculature in combination with chemotherapy in head and neck cancer. METHODS:Experimental studies were carrie...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2013.06.011

    authors: Folaron M,Kalmuk J,Lockwood J,Frangou C,Vokes J,Turowski SG,Merzianu M,Rigual NR,Sullivan-Nasca M,Kuriakose MA,Hicks WL Jr,Singh AK,Seshadri M

    更新日期:2013-09-01 00:00:00

  • External validation of the AJCC Cancer Staging Manual, 8th edition, in an independent cohort of oral cancer patients.

    abstract:OBJECTIVES:To evaluate the new American Joint Committee on Cancer (AJCC) cancer staging manual (8th edition) in an independent cohort of patients surgically treated for oral squamous cell carcinoma in order to determine whether the upstaging of pT and pN classification was indicative of a worse prognosis. METHODS:A co...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2017.05.020

    authors: Matos LL,Dedivitis RA,Kulcsar MAV,de Mello ES,Alves VAF,Cernea CR

    更新日期:2017-08-01 00:00:00

  • A systematic review of 1143 parapharyngeal space tumors reported over 20 years.

    abstract::Parapharyngeal space tumours are rare and most clinicians will only see a small number during their career. We performed a systematic review of 1143 parapharyngeal space tumors published in the past 20 years to increase cumulative experience. A systematic literature review was performed and data on histological diagno...

    journal_title:Oral oncology

    pub_type: 杂志文章,评审

    doi:10.1016/j.oraloncology.2014.02.007

    authors: Riffat F,Dwivedi RC,Palme C,Fish B,Jani P

    更新日期:2014-05-01 00:00:00

  • The lip-splitting mandibulotomy: aesthetic and functional outcomes.

    abstract::To determine the aesthetic and functional outcomes of the most invasive approach to oral cavity/oropharyngeal lesions, the lip-splitting mandibulotomy approach (LSMA), versus the least invasive, the trans-oral approach (TOA). Retrospective paired-cohort study. Thirty-six patients with oral/oropharyngeal cancers treate...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2010.05.006

    authors: Dziegielewski PT,O'Connell DA,Rieger J,Harris JR,Seikaly H

    更新日期:2010-08-01 00:00:00

  • Lip cancer experience in Mexico. An 11-year retrospective study.

    abstract::Lip cancer is the most frequent malignant neoplasm of the oral cavity; however, there is no information available on the incidence of this type of cancer in Mexico. This study provides information about the clinico-pathological features of lip cancer patients admitted at a cancer hospital in Mexico City during an 11-y...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2004.04.013

    authors: Luna-Ortiz K,Güemes-Meza A,Villavicencio-Valencia V,Mosqueda-Taylor A

    更新日期:2004-11-01 00:00:00

  • N-acetylcysteine (NAC) inhibits cell growth by mediating the EGFR/Akt/HMG box-containing protein 1 (HBP1) signaling pathway in invasive oral cancer.

    abstract:OBJECTIVES:Overexpression of the epidermal growth factor (EGF) receptor (EGFR) gene in the squamous cell carcinomas of the head and neck (SCCHN) is often associated with inauspicious prognosis and poor survival. N-acetylcysteine (NAC), a compound from some vegetables and allium species, appears anti-tumorigenesis, but ...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2012.08.003

    authors: Lee MF,Chan CY,Hung HC,Chou IT,Yee AS,Huang CY

    更新日期:2013-02-01 00:00:00

  • The association between hypoxia inducible factor-1alpha gene polymorphisms and increased susceptibility to oral cancer.

    abstract::The aim of this study was to estimate the relations between hypoxia inducible factor-1alpha (HIF-1alpha) gene polymorphisms, C1772T and G1790A, to the susceptibility and clinicopathological status of oral cancer. A total of 521 subjects, including 347 controls and 174 oral cancer patients, were recruited in this study...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2009.07.015

    authors: Chen MK,Chiou HL,Su SC,Chung TT,Tseng HC,Tsai HT,Yang SF

    更新日期:2009-12-01 00:00:00

  • Real-time PCR HPV genotyping in fine needle aspirations of metastatic head and neck squamous cell carcinoma: Exposing the limitations of conventional p16 immunostaining.

    abstract:BACKGROUND:Given the propensity for HPV-positive head and neck squamous cell carcinoma (HPV-HNSCC) to metastasize to cervical lymph nodes, fine needle aspiration (FNA) plays an important diagnostic role in their initial detection. Indeed, there is now an unwavering commitment to HPV testing of FNAs even in the absence ...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2019.02.006

    authors: El-Salem F,Mansour M,Gitman M,Miles BA,Posner MR,Bakst RL,Genden EM,Westra WH

    更新日期:2019-03-01 00:00:00

  • Clinical guidelines in early detection of oral squamous cell carcinoma arising in oral lichen planus: a 5-year experience.

    abstract::In recent years, studies on the malignant potential of oral lichen planus (OLP) provided clinical evidence that patients affected by OLP have an increased risk to develop oral squamous cell carcinoma (OSCC); nevertheless, controversies still exist as to whether OLP has inherent predisposition to become malignant, or n...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/s1368-8375(00)00096-8

    authors: Mignogna MD,Lo Muzio L,Lo Russo L,Fedele S,Ruoppo E,Bucci E

    更新日期:2001-04-01 00:00:00

  • Individualized treatment in stage IVC nasopharyngeal carcinoma.

    abstract::The stage IVC nasopharyngeal carcinoma is a catch-all entity covering minute solitary metastasis to bulky disseminated disease. Prognosis varies greatly within this stage group. A subset of patients with oligometastases may benefit from aggressive local ablative therapy. Meanwhile, in multiple metastatic diseases, cus...

    journal_title:Oral oncology

    pub_type: 杂志文章,评审

    doi:10.1016/j.oraloncology.2014.01.004

    authors: Chan OS,Ngan RK

    更新日期:2014-09-01 00:00:00

  • Clinical evaluation of the intraoral fluoride releasing system in radiation-induced xerostomic subjects. Part 2: Phase I study.

    abstract::Radiation-induced xerostomia can result in the rapid onset and progression of dental caries in head and neck cancer patients. Topically applied fluorides have been successfully used to inhibit the formation of dental caries in this population. However, because intensive daily self-application is required, compliance i...

    journal_title:Oral oncology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.oraloncology.2005.12.029

    authors: Chambers MS,Mellberg JR,Keene HJ,Bouwsma OJ,Garden AS,Sipos T,Fleming TJ

    更新日期:2006-10-01 00:00:00

  • Midkine expression in malignant salivary gland tumors and its role in tumor angiogenesis.

    abstract::The aims of this study were to investigate midkine (MK) expression patterns in salivary gland tumors (SGTs) and to evaluate the correlation between MK expression and the degree of malignancy. We performed immunohistochemistry to examine MK expression in specimens of adenoid cystic carcinoma (ACC), mucoepidermoid carci...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2010.06.004

    authors: Ota T,Ota K,Jono H,Fujimori H,Ueda M,Shinriki S,Sueyoshi T,Shinohara M,Ando Y

    更新日期:2010-09-01 00:00:00

  • The efficacy and safety of PD-1/PD-L1 inhibitors in patients with recurrent or metastatic nasopharyngeal carcinoma: A systematic review and meta-analysis.

    abstract:OBJECTIVES:There is currently no effective salvage therapeutic modality that improves the survival outcomes of patients with recurrent or metastatic nasopharyngeal carcinoma. However, the programmed cell death protein 1 (PD-1) and its ligand (PD-L1) inhibitors may provide clinical benefit for these advanced patients. ...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2020.104640

    authors: Wang BC,Cao RB,Fu C,Chen WB,Li PD,Lin GH,Qian XJ,Li YT,Liu Q

    更新日期:2020-05-01 00:00:00

  • CD40 function in squamous cell cancer of the head and neck.

    abstract::CD40 is expressed on basal keratinocytes and Squamous Cell Cancer of the Head and Neck (SCCHN) tumor cells in vivo and in vitro. CD40 ligation reduces proliferation of SCCHN cell lines and enhances EGFr mediated inhibition of proliferation. We investigated the mechanisms of CD40 function and EGFr cross-communication i...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2004.11.005

    authors: Cao W,Cavacini LA,Tillman KC,Posner MR

    更新日期:2005-05-01 00:00:00

  • Proliferative verrucous vs conventional leukoplakia: no significantly increased risk of HPV infection.

    abstract::Proliferative verrucous leukoplakia (PVL) is a very aggressive form of oral leukoplakia (OL) with high morbidity and mortality rates, hypothesised to be linked to HPV infection. This study aimed to determine the presence of HPV DNA in PVL in comparison with OL, and in relation to social-demographical variables (age, g...

    journal_title:Oral oncology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.oraloncology.2004.02.007

    authors: Campisi G,Giovannelli L,Ammatuna P,Capra G,Colella G,Di Liberto C,Gandolfo S,Pentenero M,Carrozzo M,Serpico R,D'Angelo M

    更新日期:2004-09-01 00:00:00

  • Human papillomavirus status of head and neck cancer as determined in cytologic specimens using the hybrid-capture 2 assay.

    abstract:OBJECTIVE:A standardized assay to determine the HPV status of head and neck squamous cell carcinoma (HNSCC) specimens has not yet been established, particularly for cytologic samples. The goal of this study was to determine whether the hybrid capture-2 (HC-2) assay, already widely used for the detection of high risk HP...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2014.02.011

    authors: Smith DF,Maleki Z,Coughlan D,Gooi Z,Akpeng B,Ogawa T,Bishop JA,Frick KD,Agrawal N,Gourin CG,Ha PK,Koch WM,Richmon JD,Westra WH,Pai SI

    更新日期:2014-06-01 00:00:00