Staging and IgA VCA titre in patients with nasopharyngeal carcinoma: changes over a 12-year period.

abstract：BACKGROUND:The optimal treatment for T3 glottic cancers continues to be debated. Organ preservation has become the standard of care, but not all tumors respond equally. The purpose of this was to investigate the long-term survival outcomes of organ preservation protocols based on tumor volume. METHODS:A retrospective ...

journal_title：Oral oncology

authors： Dziegielewski PT,Reschly WJ,Morris CG,DeJesus RD,Silver N,Boyce BJ,Santiago I 3rd,Amdur RJ,Mendenhall WM

更新日期：2018-04-01 00:00:00

abstract：:To determine if socio-economic status (SES) affects the stage at presentation of head and neck cancer (HNC) patients in Ottawa, Canada. To determine if the method of diagnosis affects the stage at presentation in these patients. We obtained data on SES, method of diagnosis, and stage at presentation for patients prese...

journal_title：Oral oncology

authors： Johnson S,Corsten MJ,McDonald JT,Chun J

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:We evaluated the safety of REPLICA, a CAD/CAM-designed patient-specific titanium mandible, in patients with mandibular defects not suitable for reconstruction with traditional techniques. PATIENTS AND METHODS:We performed a cohort study with a composite primary outcome assigned at the end of a 1-year follow-...

journal_title：Oral oncology

authors： Bedogni A,Bettini G,Bedogni G,Menapace G,Sandi A,Michelon F,Di Carlo R,Franco P,Saia G

更新日期：2021-01-01 00:00:00

abstract：:Head and neck squamous cell cancer (HNSCC) is the sixth most common cancer in the world. Effective therapeutic modalities such as surgery, radiation, chemotherapy and combinations of each are used in the management of this disease. Efforts are ongoing throughout the world to improve early detection and prevention of H...

journal_title：Oral oncology

authors： Sayed SI,Dwivedi RC,Katna R,Garg A,Pathak KA,Nutting CM,Rhys-Evans P,Harrington KJ,Kazi R

更新日期：2011-04-01 00:00:00

abstract：:We evaluated the prognostic significance of p34cdc2 expression in 50 tongue squamous cell carcinomas (SCC) using immunohistochemical methods. The p34cdc2 protein was expressed in 33 cases of 50 tumor tissues (66.0%), compared with 15 cases of 42 controlled epithelia (35.7%). The expression of p34cdc2 was significantly...

journal_title：Oral oncology

authors： Wada S,Yue L,Furuta I

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVES:Healthy life expectancy, an extension of the concept of life expectancy, is a summary measure of population health that takes into account the mortality and morbidity of a population. The aim of the present study was to retrospectively analyze the self-reliance survival times of oral squamous cell carcinoma ...

journal_title：Oral oncology

authors： Yamada SI,Kurita H,Tomioka T,Ohta R,Yoshimura N,Nishimaki F,Koyama Y,Kondo E,Kamata T

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVES:Head and neck cancer patients and their caregivers report high rates of psychological distress. High rates of physical symptom burden and the increased need for family members to provide caregiving during treatment may contribute to this distress. METHODS:This study examined trajectories of patient and care...

journal_title：Oral oncology

authors： Badr H,Gupta V,Sikora A,Posner M

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:The 2017 National Comprehensive Cancer Network Clinical Practice Guidelines recommend surgical resection or definitive radiation therapy for early-stage oral cavity malignancies, and surgical resection or multimodality clinical trials for late-stage disease. Few studies have been conducted to identify predic...

journal_title：Oral oncology

authors： Fujiwara RJT,Burtness B,Husain ZA,Judson BL,Bhatia A,Sasaki CT,Yarbrough WG,Mehra S

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVES:Surgical management of patients following zoledronic acid therapy is particularly difficult, since the dental extraction is the main cause of BRONJ. METHODS:A case-control study was conducted on 176 patients treated with intravenous (IV) bisphosphonates for oncologic pathologies who also underwent dental ex...

journal_title：Oral oncology

authors： Mozzati M,Arata V,Gallesio G

更新日期：2012-09-01 00:00:00

abstract：:Incidence of oropharyngeal squamous cell carcinoma (OSCC) increased 3% annually from 1973 to 2001. OSCC's can be attributed to tobacco and alcohol, but 25% are unlinked to typical risks. Case-control studies on HPV detection in non-smoking/non-drinking (NS/ND) OSCC patients have not previously been performed. The prim...

journal_title：Oral oncology

authors： Andrews E,Seaman WT,Webster-Cyriaque J

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVES:Serologic analyses for anti-EBV antibodies used alone usually have low sensitivity for the diagnosis of nasopharyngeal carcinoma (NPC). We assumed that a combined determination of antibodies directed at EBV proteins expressed in both lytic and latent cycles could increase the sensitivity. MATERIALS AND METH...

journal_title：Oral oncology

authors： Ai P,Wang T,Zhang H,Wang Y,Song C,Zhang L,Li Z,Hu H

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVES:There exist no uniform decision criteria for conservative organ preservation treatments in head and neck cancer patients. Even with 18F-FDG-PET/CT after induction chemotherapy patient selection is challenging. This study correlated metabolic tumor response with treatment types and recurrence patterns. MATER...

journal_title：Oral oncology

authors： Semrau S,Schmidt D,Hecht M,Haderlein M,Kitzsteiner C,Müller S,Traxdorf M,Agaimy A,Iro H,Kuwert T,Fietkau R

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:In carefully selected oral cavity cancers, marginal mandibulectomy is an adequate procedure which achieves good disease control adhering to the principle of "doing as little as possible and as much as necessary". METHODOLOGY:This was a retrospective study done by reviewing the medical records of all patient...

journal_title：Oral oncology

authors： Suresh S,Thomas S,Janardhan D,Patil S,George NA,Varghese BT,Iype EM,Rafi M,George CK

更新日期：2019-08-01 00:00:00

abstract：:Oral cancer models have attempted to demonstrate inhibition of oral carcinogenesis. These models used synthetic carcinogens, lacked a specific mechanism of activity or used non-physiologic doses for carcinogen or inhibitor. To correct these problems the tobacco and environmental carcinogen, dibenzo[a,l]pyrene (DB[a,l]...

journal_title：Oral oncology

authors： Schwartz J,Baker V,Larios E,Desai D,Amin S

更新日期：2004-07-01 00:00:00

abstract：:Toll-like receptor 4 (TLR4) plays a significant role in cancer therapy as receptors of bacteria-derived immunotherapeutic agents such as OK-432, a streptococcal immunotherapeutic agent. In addition, recent reports demonstrated that TLRs, including TLR4, are also expressed in cancer cells as well as in immunocompetent ...

journal_title：Oral oncology

authors： Tano T,Okamoto M,Kan S,Nakashiro K,Shimodaira S,Yamashita N,Kawakami Y,Hamakawa H

更新日期：2012-08-01 00:00:00

abstract：:Cell lines developed from head and neck squamous cell carcinomas exhibit variable responses to the negative regulatory effects of transforming growth factor beta (TGF beta) on cell growth. To analyse the effects of TGF beta on regulators of cell cycle progression, we characterised cell lines derived from head and neck...

journal_title：Oral oncology

authors： Lesaca EE,Ensley JF,Yeudall WA

更新日期：1998-01-01 00:00:00

abstract：:We established a new evaluation system for metastatic potential of oral squamous cell carcinoma (SCC), utilizing a combined examination of histopathological grades of the carcinomas based on cell differentiation and invasive mode according to Yamamoto's criteria, and the cellular expressions of CD44, E-cadherin (E-cad...

journal_title：Oral oncology

authors： Mori S,Nose M,Morikawa H,Sato A,Saito T,Song ST,Tanda N,Teshima T

更新日期：1998-11-01 00:00:00

abstract：:Oral leukoplakia is a potentially malignant disorder that will develop into oral cancer at an estimated rate of 1-2% per year. Aim of the present study is to assess the possible predictive value of DNA ploidy for malignant progression of oral leukoplakia. A cohort of 62 leukoplakia patients was studied and their biops...

journal_title：Oral oncology

authors： Bremmer JF,Brakenhoff RH,Broeckaert MA,Beliën JA,Leemans CR,Bloemena E,van der Waal I,Braakhuis BJ

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:The incidence of nasopharyngeal carcinoma (NPC) is higher in Chinese than in Caucasian populations. Genetic, viral, and lifestyle factors may explain these ethnic differences in the incidence of NPC. In the present study, we examined the familial aggregation, heritability, and relative risks (RRs) of NPC usi...

journal_title：Oral oncology

authors： Huang SF,Hsiao JH,Young CK,Chien HT,Kuo CF,See LC,Luo SF,Huang LH,Liao CT,Chang TJ

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVES:Angiotensin I-converting enzyme (ACE), a type I cell surface zinc metallopeptidase, is differentially expressed in several malignancies and plays a role in tumor cell proliferation, tumor cell migration, angiogenesis, and metastatic behavior. We aimed to investigate the effects of ACE gene (rs1799752) varian...

journal_title：Oral oncology

authors： Liu YT,Lin LW,Chen CY,Wang CP,Liu HP,Houng JY,Chung FM,Shieh TY

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Hypothesizing that neck-level specific locations of residual lymph node metastases following chemoradiation for head and neck cancer are highly predictable, the efficacy of the more targeted lymphadenectomy procedure called super-selective neck dissection (SSND) was evaluated. METHODS:A retrospective analys...

journal_title：Oral oncology

authors： Robbins KT,Dhiwakar M,Vieira F,Rao K,Malone J

更新日期：2012-11-01 00:00:00

abstract：:Similar to actors changing costumes during a performance, cancer cells undergo many rapid changes during the process of tumor metastasis, including epithelial-mesenchymal transition (EMT), acquisition of cancer stem cells (CSCs) properties, and mesenchymal-epithelial transition (MET). Such changes allow the tumor to c...

journal_title：Oral oncology

authors： Zhou C,Liu J,Tang Y,Liang X

更新日期：2012-11-01 00:00:00

abstract：:The aim was to determine the immediate influence of a validated patient information leaflet (PIL) on oral cancer and knowledge in primary care attenders. Participants were patients (n=800) attending their primary health care provider from 14 general practices (eight dental and six medical) in the north west of England...

journal_title：Oral oncology

authors： Humphris GM,Ireland RS,Field EA

更新日期：2001-01-01 00:00:00

abstract：:Maxillary defects can be resolved by prosthetic obturation, autologous tissue reconstruction, or a combination of both. However, there is still controversy in the selection of the optimal approach. Therefore, the aim of this study was to systematically review evidences comparing the performance of obturators and flaps...

journal_title：Oral oncology

authors： Cao Y,Yu C,Liu W,Miao C,Han B,Yang J,Li L,Li C

更新日期：2018-07-01 00:00:00

abstract：:Integrins are a family of heterodimeric, cation-dependent cell membrane adhesion molecules which mediate cell-cell and cell-matrix interactions. They play a fundamental role in the maintenance of tissue integrity and in the regulation of cell proliferation, growth, differentiation and migration. It is not surprising, ...

journal_title：Oral oncology

authors： Thomas GJ,Jones J,Speight PM

更新日期：1997-11-01 00:00:00

abstract：OBJECTIVES:Diffusion weighted imaging (DWI) is a frequently performed MRI sequence in cancer patients. While previous studies have shown the clinical value of the apparent diffusion coefficient (ADC) for response prediction and response monitoring, less is known about the biological background of ADC. In the tumor micr...

journal_title：Oral oncology

authors： Swartz JE,Driessen JP,van Kempen PMW,de Bree R,Janssen LM,Pameijer FA,Terhaard CHJ,Philippens MEP,Willems S

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVES:We sought to describe the genetic complexity of 14 UM-SCC oral cavity cancer cell lines that have remained uncharacterized despite being used as model systems for decades. MATERIALS AND METHODS:We performed exome sequencing on 14 oral cavity UM-SCC cell lines and denote the mutational profile of each line. ...

journal_title：Oral oncology

authors： Ludwig ML,Kulkarni A,Birkeland AC,Michmerhuizen NL,Foltin SK,Mann JE,Hoesli RC,Devenport SN,Jewell BM,Shuman AG,Spector ME,Carey TE,Jiang H,Brenner JC

更新日期：2018-12-01 00:00:00

abstract：:Recent evidence has consistently suggested a role for HCV in the etiology of head and neck squamous cell carcinoma (HNSCC), but the conclusions of these studies have often been limited by small sample size. Therefore, a meta-analysis was performed to summarize present evidence on the association between HCV infection ...

journal_title：Oral oncology

authors： Borsetto D,Fussey J,Fabris L,Bandolin L,Gaudioso P,Phillips V,Polesel J,Boscolo-Rizzo P

更新日期：2020-06-26 00:00:00

abstract：UNLABELLED:Despite significant advances in surgical procedures and treatment, long-term prognosis for patients with oral cancer remains poor, with survival rates among the lowest of major cancers. Better methods are desperately needed to identify potential malignancies early when treatments are more effective. OBJECTI...

journal_title：Oral oncology

authors： Abram TJ,Floriano PN,Christodoulides N,James R,Kerr AR,Thornhill MH,Redding SW,Vigneswaran N,Speight PM,Vick J,Murdoch C,Freeman C,Hegarty AM,D'Apice K,Phelan JA,Corby PM,Khouly I,Bouquot J,Demian NM,Weinstock YE,

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVES:Platinum-based chemotherapy is the recognized first-line treatment for metastatic nasopharyngeal carcinoma (NPC). However there is no standard second-line treatment. This study was designed to evaluate the efficacy and safety of a gemcitabine and vinorelbine combination (GV) in patients with metastatic NPC p...

journal_title：Oral oncology

authors： Chen C,Wang FH,Wang ZQ,An X,Luo HY,Zhang L,Chen YC,Xu RH,Li YH

更新日期：2012-11-01 00:00:00