Obturators versus flaps after maxillary oncological ablation: A systematic review and best evidence synthesis.

abstract：OBJECTIVES:Examine the effect of concordance between p16 overexpression and HR (high risk) HPV DNA status on overall survival in a large series of oropharyngeal squamous cell carcinoma (OPSCC) cases. MATERIALS AND METHODS:A total of 185 patients with primary OPSCC had genomic DNA tested by PCR for the HPV16 E6 and E7 ...

journal_title：Oral oncology

authors： Liu SZ,Zandberg DP,Schumaker LM,Papadimitriou JC,Cullen KJ

更新日期：2015-09-01 00:00:00

abstract：:We investigated the knowledge and behaviors of a random sample of 500 primary care physicians (PCPs) regarding oral cancer in Calabria (Italy). 87.6% and 64% indicated tobacco and alcohol use as risk factors, only 31.5% and 2.8% having a prior oral cancer lesion and older age. 60.9% knew that squamous-cell carcinoma i...

journal_title：Oral oncology

authors： Nicotera G,Di Stasio SM,Angelillo IF

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVES:Adenoid cystic carcinoma (ACC) is one of the most common malignancies of salivary glands, characterized by poor prognosis, particularly due to pulmonary metastasis. We previously reported that transforming growth factor (TGF)-β1 promoted ACC cell migration and invasion via the Smad pathway in vitro. The aim ...

journal_title：Oral oncology

authors： Dong L,Ge XY,Wang YX,Yang LQ,Li SL,Yu GY,Gao Y,Fu J

更新日期：2013-11-01 00:00:00

abstract：:Oral squamous cell carcinoma (OSCC) is characterized by high mortality rates. High incidence of local recurrences in the normal-appearing surgical margins of OSCC patients indicates the existence molecular alterations, including DNA methylation, which could not be detectable by histopathologic analysis. The objective ...

journal_title：Oral oncology

authors： Supic G,Kozomara R,Jovic N,Zeljic K,Magic Z

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVES:Feeding tubes are placed unnecessarily in a proportion of head and neck cancer (HNC) patients treated with chemoradiotherapy (CRT) when prophylactic tube placement protocols are used. This may have a negative impact on the risk of long-term dysphagia. Reactive tube placement protocols, on the other hand, mig...

journal_title：Oral oncology

authors： Karsten RT,Stuiver MM,van der Molen L,Navran A,de Boer JP,Hilgers FJM,Klop WMC,Smeele LE

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVES:Though the effect of age has been studied in some cancer types, its prognostic significance in oropharyngeal squamous cell carcinoma (OPSCC) remains controversial. Our purpose is to determine the impact of age at diagnosis on overall survival (OS) and disease-specific survival (DSS) in patients with OPSCC. I...

journal_title：Oral oncology

authors： Ryan Camilon P,Stokes WA,Nguyen SA,Lentsch EJ

更新日期：2014-05-01 00:00:00

abstract：:Head and neck malignant tumors are classified according to the TNM staging system. The TNM system is a universally accepted, widely used, staging method. Its goals are to help clinicians and researchers to choose from treatment options, to give patients an estimate of their prognosis and to compare results of treatmen...

journal_title：Oral oncology

authors： van der Schroeff MP,Baatenburg de Jong RJ

更新日期：2009-04-01 00:00:00

abstract：:Expression profile of 588 known genes relating to tumour biology, was examined between oral squamous cell carcinomas (OSCCs) and matching normal oral mucosal tissues (NOMTs) obtained from Sudanese (n=11) and Norwegian (n=11) patients. cDNA probes were synthesised from total RNA and hybridised with the Atlas human canc...

journal_title：Oral oncology

authors： Ibrahim SO,Aarsaether N,Holsve MK,Kross KW,Heimdal JH,Aarstad JH,Liavaag PG,Elgindi OA,Johannessen AC,Lillehaug JR,Vasstrand EN

更新日期：2003-01-01 00:00:00

abstract：:Oral cancer is a potentially preventable disease due to its association with well-known risk factors and easy detectability. There is a significant deficiency in the awareness of oral cancer and its risk factors among the public. Raising public awareness could effectively contribute to achieving a significant reductio...

journal_title：Oral oncology

authors： Elango KJ,Anandkrishnan N,Suresh A,Iyer SK,Ramaiyer SK,Kuriakose MA

更新日期：2011-07-01 00:00:00

abstract：:The aim of this study was to determine the survival rate of oral cancer patients treated in a medical center in central Taiwan and to investigate whether socio-demographic factors influence their survival. We retrospectively reviewed 1010 chart records of oral cancer patients. Survival was analyzed by the Kaplan-Meier...

journal_title：Oral oncology

authors： Wong YK,Tsai WC,Lin JC,Poon CK,Chao SY,Hsiao YL,Chan MY,Cheng CS,Wang CC,Wang CP,Liu SA

更新日期：2006-10-01 00:00:00

abstract：:Conventional surgical approaches for tonsillar carcinomas have a great risk for developing treatment-related morbidity. To minimize this morbidity, transoral lateral oropharyngectomy (TLO) using the robotic surgical system was performed, and the efficacy and feasibility of this procedure was evaluated. TLO was perform...

journal_title：Oral oncology

authors： Park YM,Lee JG,Lee WS,Choi EC,Chung SM,Kim SH

更新日期：2009-08-01 00:00:00

abstract：:Metallothioneins (MTs) are a family of low molecular weight, cysteine-rich, inducible, intracellular proteins that bind heavy metals with high affinity. MT-1 is known as a stress-inducible protein and functions as an antioxidant enzyme. Areca quid chewing is a major risk factor in the development and further progressi...

journal_title：Oral oncology

authors： Lee SS,Yang SF,Ho YC,Tsai CH,Chang YC

更新日期：2008-02-01 00:00:00

abstract：:The aim of this study is to assess the impact of prognostic factors in patients with locoregionally advanced nasopharyngeal cancer (NPC), WHO type II-III, treated with two different radiation therapy (RT) schedules: standard radiation therapy (SRT), and accelerated hyperfractionated radiation therapy (HART), with or w...

journal_title：Oral oncology

authors： Franchin G,Vaccher E,Talamini R,Gobitti C,Minatel E,Politi D,Sartor G,Trovò MG,Barzan L

更新日期：2002-02-01 00:00:00

abstract：:Despite easy access to clinical examination majority of oral cancer patients ironically present with locally advanced disease, which is a heterogeneous group that includes all stage III/IV tumours in absence of distant metastasis. The AJCC TNM classification has included all tumours with depth of invasion >1 cm into l...

journal_title：Oral oncology

authors： Dhar H,Vaish R,D'Cruz AK

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:The use of transoral robotic surgery (TORS) and laser microsurgery (TLM) in the diagnosis and identification of the site of the unknown primary has become increasingly common. This systematic review and meta-analysis aims to assess the use and efficacy of TORS and TLM for this indication. METHOD:Systematic ...

journal_title：Oral oncology

authors： Farooq S,Khandavilli S,Dretzke J,Moore D,Nankivell PC,Sharma N,Almeida JR,Winter SC,Simon C,Paleri V,De M,Siddiq S,Holsinger C,Ferris RL,Mehanna H

更新日期：2019-04-01 00:00:00

abstract：:Hematogenous metastasis is one of the most important factors determining the outcome of the patients with salivary adenoid cystic carcinoma (SACC). In the present study, we examined expression profile of genes in SACC cell lines to look for molecules responsible for its unique metastatic trait. A transcriptomic microa...

journal_title：Oral oncology

authors： Hu K,Li SL,Gan YH,Wang CY,Yu GY

更新日期：2009-02-01 00:00:00

abstract：:Hyalinizing clear cell carcinoma (HCCC) is a recently described low-grade carcinoma of the salivary glands presenting two main histological features: clear neoplastic cells and prominent hyalinized stroma. Our aim was to characterize the composition of the hyalinized stroma in three cases of HCCC. An immuno-histochemi...

journal_title：Oral oncology

authors： Félix A,Rosa JC,Nunes JF,Fonseca I,Cidadão A,Soares J

更新日期：2002-06-01 00:00:00

abstract：:To define the role of surgical management of lung metastases in ACC. Twenty ACC patients referred to lung metastasectomy were retrospectively reviewed. Twenty-six operations were performed; at the first metastasectomy, a resection with clear margins (R0) was achieved in 11 patients (55%), 3 are alive and well. Four ou...

journal_title：Oral oncology

authors： Locati LD,Guzzo M,Bossi P,Massone PP,Conti B,Fumagalli E,Bareggi C,Cantù G,Licitra L

更新日期：2005-10-01 00:00:00

abstract：OBJECTIVES:Genetic polymorphisms of genes in cell cycle, apoptosis, and inflammation/immune response pathways may control the mechanisms of HPV clearance and HPV escape of immune surveillance and thus may affect both tumor HPV16 status and possibly related outcomes of squamous cell carcinoma of the oropharynx (SCCOP) p...

journal_title：Oral oncology

authors： Feng Y,Li Y,Zhang Y,Zheng H,Li G

更新日期：2016-05-01 00:00:00

abstract：:Retinoids are the natural and synthetic derivatives of vitamin A. Epidemiological studies indicate that a low intake of vitamin A is associated with an increased risk of squamous cancer. In vitro studies on cancer cells show that exposure to retinoids results in the inhibition of growth, by blocking the cell cycle or ...

journal_title：Oral oncology

authors： Klaassen I,Braakhuis BJ

更新日期：2002-09-01 00:00:00

abstract：:Immunoreactivity of proliferating cell nuclear antigen (PCNA) was assessed in formalin-fixed, paraffin-embedded sections from human normal parotid gland (N; n = 12), chronic sialadenitis (CS; n = 8), Warthin's tumour (W; n = 10), benign pleomorphic adenoma (BPA; n = 11), mucoepidermoid carcinoma (MEC; n = 14), carcino...

journal_title：Oral oncology

authors： Zhu Q,White FH,Tipoe GL

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:The programmed death pathway plays a role in persistent human papillomavirus (HPV) infection as well as in resistance to immune elimination during malignant progression. In this study, we examined PD-L1 expression by immunohistochemistry and tumour infiltrating lymphocytes (TIL) in 214 patients with orophary...

journal_title：Oral oncology

authors： Hong AM,Ferguson P,Dodds T,Jones D,Li M,Yang J,Scolyer RA

更新日期：2019-05-01 00:00:00

abstract：:Head and neck cancers during pregnancy are rising in incidence. Clinicians need to be aware of the principles of managing these cases. This paper is a review of the literature of head and neck cancers during pregnancy with a short case series of six non-thyroid pregnancy-associated cancers treated by a head and neck o...

journal_title：Oral oncology

authors： Atabo A,Bradley PJ

更新日期：2008-03-01 00:00:00

abstract：:The high frequency of second or third primary tumors was first explained by Slaughter et al. with the concept of field cancerisation. Another theory postulates micrometastatic lesions as a reason for this phenomenon. The micronuclei (MN)-assay was evaluated to provide evidence for the concept of field cancerisation an...

journal_title：Oral oncology

authors： Bloching M,Hofmann A,Lautenschläger C,Berghaus A,Grummt T

更新日期：2000-11-01 00:00:00

abstract：OBJECTIVES:Human papillomavirus infection and p16-overexpression is a principal cause and favorable prognostic factor for oropharyngeal squamous cell carcinomas but the value as prognostic marker in oral cavity squamous cell carcinomas (OSCC) is undetermined. MATERIALS AND METHODS:All patients diagnosed with OSCC in E...

journal_title：Oral oncology

authors： Schneider K,Jakobsen KK,Jensen JS,Wessel I,Christensen A,Specht L,Lelkaitis G,Mirian C,Buchwald CV,Grønhøj C

更新日期：2020-12-01 00:00:00

abstract：:Although the amelogenin gene is expressed in ameloblastoma, the precise expression pattern of X and Y amelogenin genes (AMGX, AMGY) in this tumor has not yet been identified. In this study, we analyzed amelogenin gene expression in 19 samples (9 male, 10 female) of oral ameloblastomas by RT-PCR and detect the chromoso...

journal_title：Oral oncology

authors： Tsujigiwa H,Nagatsuka H,Han PP,Gunduz M,Siar CH,Oida S,Nagai N

更新日期：2005-09-01 00:00:00

abstract：:Toll-like receptor 4 (TLR4) plays a significant role in cancer therapy as receptors of bacteria-derived immunotherapeutic agents such as OK-432, a streptococcal immunotherapeutic agent. In addition, recent reports demonstrated that TLRs, including TLR4, are also expressed in cancer cells as well as in immunocompetent ...

journal_title：Oral oncology

authors： Tano T,Okamoto M,Kan S,Nakashiro K,Shimodaira S,Yamashita N,Kawakami Y,Hamakawa H

更新日期：2012-08-01 00:00:00

abstract：:MicroRNAs (miRNAs) play important roles in neoplastic process. miR-24 is localized on chromosome 9q22 and 19p13, regions frequently altered in oral squamous cell carcinoma (OSCC). This study showed that miR-24 was up-regulated in OSCC tissues relative to control samples. In addition, the plasma levels of miR-24 in OSC...

journal_title：Oral oncology

authors： Lin SC,Liu CJ,Lin JA,Chiang WF,Hung PS,Chang KW

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVES:Diffusion weighted imaging (DWI) is a frequently performed MRI sequence in cancer patients. While previous studies have shown the clinical value of the apparent diffusion coefficient (ADC) for response prediction and response monitoring, less is known about the biological background of ADC. In the tumor micr...

journal_title：Oral oncology

authors： Swartz JE,Driessen JP,van Kempen PMW,de Bree R,Janssen LM,Pameijer FA,Terhaard CHJ,Philippens MEP,Willems S

更新日期：2018-02-01 00:00:00

abstract：INTRODUCTION:Disruption of E-cadherin function and increased expression of vimentin and the transcriptional oncogene, SOX2, are thought to characterize epithelial to mesenchymal transition (EMT) in HNSCC that contributes to invasive and metastatic behavior. To determine if such changes relate to prognosis or host immun...

journal_title：Oral oncology

authors： Wolf GT,Winter W,Bellile E,Nguyen A,Donnelly CR,McHugh JB,Thomas D,Amlani L,Rozek L,Lei YL,Head and Neck SPORE Program.

更新日期：2018-12-01 00:00:00