Abstract：
:Despite easy access to clinical examination majority of oral cancer patients ironically present with locally advanced disease, which is a heterogeneous group that includes all stage III/IV tumours in absence of distant metastasis. The AJCC TNM classification has included all tumours with depth of invasion >1 cm into locally advanced group irrespective of their surface dimensions. Surgery followed by adjuvant therapy provides best results and should be offered to all patients when operable. There have been a slew of recent publications popularising the concept of compartmental excision in variance to traditional resection with adequate margins. The role of chemotherapy has been explored in this group of patients for both organ preservation as well as to aid bioselection of suitable patients with borderline operable tumours for surgery.
journal_name
Oral Oncoljournal_title
Oral oncologyauthors
Dhar H,Vaish R,D'Cruz AKdoi
10.1016/j.oraloncology.2020.104662subject
Has Abstractpub_date
2020-06-01 00:00:00pages
104662eissn
1368-8375issn
1879-0593pii
S1368-8375(20)30098-1journal_volume
105pub_type
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