Correlation of p16 expression and HPV type with survival in oropharyngeal squamous cell cancer.

abstract：:Periodontal infection may exacerbate during cancer therapy and may result in oral pain and infection, and systemic infection, which may cause morbidity and can lead to mortality in neutropenic cancer patients. Periodontal disease in head and neck cancer patients treated with radiation therapy may lead to acute and chr...

journal_title：Oral oncology

authors： Epstein JB,Stevenson-Moore P

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVES:The hepatocyte growth factor receptor (Met) is frequently overexpressed in Head and Neck Squamous Cell Carcinoma (HNSCC), correlating positively with high-grade tumors and shortened patient survival. As such, Met may represent an important therapeutic target. The purpose of this study was to explore the role...

journal_title：Oral oncology

authors： Tao X,Hill KS,Gaziova I,Sastry SK,Qui S,Szaniszlo P,Fennewald S,Resto VA,Elferink LA

更新日期：2014-02-01 00:00:00

abstract：:We investigated the knowledge and behaviors of a random sample of 500 primary care physicians (PCPs) regarding oral cancer in Calabria (Italy). 87.6% and 64% indicated tobacco and alcohol use as risk factors, only 31.5% and 2.8% having a prior oral cancer lesion and older age. 60.9% knew that squamous-cell carcinoma i...

journal_title：Oral oncology

authors： Nicotera G,Di Stasio SM,Angelillo IF

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVES:While surgery with or without adjuvant radiation therapy (RT) is the standard of care for oral cavity cancer (OCC), a select group requires nonsurgical treatment. We provide a single-institution experience using definitive chemotherapy and RT for primary OCC. MATERIALS AND METHODS:We examined 73 patients wi...

journal_title：Oral oncology

authors： Scher ED,Romesser PB,Chen C,Ho F,Wuu Y,Sherman EJ,Fury MG,Wong RJ,McBride S,Lee NY,Riaz N

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVES:Head and neck radiotherapy can cause several toxicities, and its management has important treatment implications. Proper information about treatment is crucial to assist patients by preparing them and enhancing their ability to manage their illness. Thus, this study aimed to verify the impact of an education...

journal_title：Oral oncology

authors： Fernandes DT,Prado-Ribeiro AC,Markman RL,Morais K,Moutinho K,Tonaki JO,Brandão TB,Rivera C,Santos-Silva AR,Lopes MA

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVES:We sought to describe the genetic complexity of 14 UM-SCC oral cavity cancer cell lines that have remained uncharacterized despite being used as model systems for decades. MATERIALS AND METHODS:We performed exome sequencing on 14 oral cavity UM-SCC cell lines and denote the mutational profile of each line. ...

journal_title：Oral oncology

authors： Ludwig ML,Kulkarni A,Birkeland AC,Michmerhuizen NL,Foltin SK,Mann JE,Hoesli RC,Devenport SN,Jewell BM,Shuman AG,Spector ME,Carey TE,Jiang H,Brenner JC

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:Nasopharyngeal carcinoma (NPC) is common in Southeast Asia. Due to the influx of immigrants from this region, the incidence in British Columbia is increasing. Current literature from non-endemic populations encompasses heterogeneous cohorts. This study examines NPC in a North American population, with a high ...

journal_title：Oral oncology

authors： Howlett J,Hamilton S,Ye A,Jewett D,Riou-Green B,Prisman E,Thamboo A

更新日期：2021-01-24 00:00:00

abstract：:Radiation-induced xerostomia can result in the rapid onset and progression of dental caries in head and neck cancer patients. Topically applied fluorides have been successfully used to inhibit the formation of dental caries in this population. However, because intensive daily self-application is required, compliance i...

journal_title：Oral oncology

authors： Chambers MS,Mellberg JR,Keene HJ,Bouwsma OJ,Garden AS,Sipos T,Fleming TJ

更新日期：2006-10-01 00:00:00

abstract：:A series of patients with oral squamous cell carcinoma (SCC) observed at the "Regina Elena" Cancer Institute was retrospectively reviewed in order to analyse the risk factors for multiple and second primary tumours (SPTs), their impact on survival and effective measures to control this phenomenon. In a survey of 200 i...

journal_title：Oral oncology

authors： Cianfriglia F,Di Gregorio DA,Manieri A

更新日期：1999-03-01 00:00:00

abstract：:The aim of this study was to define the appropriate fractionation interval between photodynamic therapies (PDTs) for enhanced anti-tumour effects on human oral squamous cell carcinoma (HOSCC). Reoxygenation of HOSCC and the proliferative kinetics of the tumour cells following PDT exposure were evaluated in terms of im...

journal_title：Oral oncology

authors： Togashi H,Uehara M,Ikeda H,Inokuchi T

更新日期：2006-05-01 00:00:00

abstract：:Oral malignant melanoma is uncommon, accounting for 1-8% of all malignant melanomas. All previous papers have reported small numbers of cases or have retrospectively reviewed case reports from the literature. The following case reports concern malignant melanoma of the oral cavity seen at the Instituto Nacional de Can...

journal_title：Oral oncology

authors： Lopez-Graniel CM,Ochoa-Carrillo FJ,Meneses-García A

更新日期：1999-07-01 00:00:00

abstract：:We hope to establish a new readmission prediction score for patients with head and neck cancer (HNC) after major cancer surgery. A retrospective cohort study was conducted from the clinical and cancer registry data at Kaohsiung Veterans General Hospital. We included the data of patients with newly diagnosed HNC who un...

journal_title：Oral oncology

authors： Yin CH,Kang BH,Liu WS,Pan LF,Chen HM,Lee CC

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVES:Recent preclinical research has renewed interest in the interplay between glucose dysregulation and cancer. Metformin holds promise as an adjunctive antineoplastic agent in head and neck cancer (HNC). We aimed to explore the impact of metformin in HNC patients from a population-based dataset. PATIENTS & MET...

journal_title：Oral oncology

authors： Stokes WA,Eguchi M,Amini A,Hararah MK,Ding D,McDermott JD,Bradley CJ,Karam SD

更新日期：2018-09-01 00:00:00

abstract：:The submental artery island flap (SIF) is gaining acceptance as a simple and reliable option in selected oral oncologic reconstructions. The present study aims to assess the usefulness of submental artery flap in oral reconstruction with respect to flap reliability, cosmesis, function, donor site morbidity and oncolog...

journal_title：Oral oncology

authors： Sebastian P,Thomas S,Varghese BT,Iype EM,Balagopal PG,Mathew PC

更新日期：2008-11-01 00:00:00

abstract：:The present investigation has examined the clinical benefits of tobramycin, polymyxin E and amphotericin therapy in the management of oral mucositis in children undergoing chemotherapy prior to bone marrow transplantation. Tobramycin, polymyxin E, and amphotericin reduced the degree of oral mucositis more than convent...

journal_title：Oral oncology

authors： Bondi E,Baroni C,Prete A,Gatti M,Carrassi A,Lodi G,Porter SR

更新日期：1997-09-01 00:00:00

abstract：:The aims of this study were to investigate midkine (MK) expression patterns in salivary gland tumors (SGTs) and to evaluate the correlation between MK expression and the degree of malignancy. We performed immunohistochemistry to examine MK expression in specimens of adenoid cystic carcinoma (ACC), mucoepidermoid carci...

journal_title：Oral oncology

authors： Ota T,Ota K,Jono H,Fujimori H,Ueda M,Shinriki S,Sueyoshi T,Shinohara M,Ando Y

更新日期：2010-09-01 00:00:00

abstract：:The FHIT (fragile histidine triad) gene at chromosome 3p14.2 spans the FRA3B fragile site and encodes for a diadenosine triphosphate hydrolase-type protein. FHIT is frequently abnormal in solid tumours including those of the upper aerodigestive tract (UAT) and has therefore been proposed as a tumour-suppressor gene. T...

journal_title：Oral oncology

authors： Pateromichelakis S,Lee G,Langdon JD,Partridge M

更新日期：2000-03-01 00:00:00

abstract：OBJECTIVE:Clear cell odontogenic carcinoma (CCOC) is a rare malignant odontogenic tumor (MOT) characterized by sheets and lobules of vacuolated and clear cells. To understand the biology of CCOC, we established a new cell line, CCOC-T, with EWSR1-ATF1 fusion gene from a mandible tumor with distant metastasis and charac...

journal_title：Oral oncology

authors： Kujiraoka S,Tsunematsu T,Sato Y,Yoshida M,Ishikawa A,Tohyama R,Tanaka M,Kobayashi Y,Kondo T,Ushio A,Otsuka K,Kurosawa M,Saito M,Yamada A,Arakaki R,Nagai H,Nikai H,Takeuchi K,Nagao T,Miyamoto Y,Ishimaru N,Kudo Y

更新日期：2017-06-01 00:00:00

abstract：:Keratins have been extensively studied in tissues and cultured keratinocytes but limited information is available on epithelia reconstructed in vitro. The aim of this study was to examine keratin expression in organotypic epithelia with normal (NOK), immortalized (SVpgC2a) and malignant (SqCC/Y1) human buccal cells. O...

journal_title：Oral oncology

authors： Hansson A,Bloor BK,Haig Y,Morgan PR,Ekstrand J,Grafström RC

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVES:Platinum-based chemotherapy is the recognized first-line treatment for metastatic nasopharyngeal carcinoma (NPC). However there is no standard second-line treatment. This study was designed to evaluate the efficacy and safety of a gemcitabine and vinorelbine combination (GV) in patients with metastatic NPC p...

journal_title：Oral oncology

authors： Chen C,Wang FH,Wang ZQ,An X,Luo HY,Zhang L,Chen YC,Xu RH,Li YH

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:This study tested the long-term outcomes of sentinel lymph node biopsy (SLNB) for oral tongue squamous cell carcinoma (SCC) during the transition from validation to application phase. MATERIALS AND METHODS:Sensitivity, negative predictive value (NPV), neck control rate, disease-specific survival (DSS), disea...

journal_title：Oral oncology

authors： Chung MK,Lee GJ,Choi N,Cho JK,Jeong HS,Baek CH

更新日期：2015-10-01 00:00:00

abstract：:The Wnt pathway is involved in carcinogenesis and three regulatory genes of the Wnt pathway, APC (adenomatous polyposis coli), beta-catenin and Axin are frequently mutated in some primary human cancers. This study was conducted to clarify the relation of beta-catenin accumulation and the mutation of the CTNNB1 (beta-c...

journal_title：Oral oncology

authors： Siriwardena BS,Kudo Y,Ogawa I,Tilakaratne WM,Takata T

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:To analyse the survival and late toxicities of elderly nasopharyngeal carcinoma (NPC) patients treated by intensity-modulated radiotherapy (IMRT) with the high-total- and fractionated-dose simultaneous modulated accelerated radiation therapy (SMART) boost technique and to identify the effect of concurrent ch...

journal_title：Oral oncology

authors： Miao J,Wang L,Zhu M,Xiao W,Wu H,Di M,Huang Y,Huang S,Han F,Deng X,Guo X,Zhao C

更新日期：2019-03-01 00:00:00

abstract：:The distributions of 2093 patients with nasopharyngeal carcinoma (NPC), by stage, over a 12-year-period did not show any evidence of a shift towards early stages despite growing awareness of this prevalent malignancy. The IgA VCA titre was determined for 1880 of these patients. The median titre increased from 40 in st...

journal_title：Oral oncology

authors： Ho S,Teo P,Kwan WH,Choi P,Tjong J,Johnson PJ

更新日期：1998-11-01 00:00:00

abstract：:Salivary duct carcinoma (SDC) is a rare, aggressive salivary malignancy that is often diagnosed at an advanced stage. Previously, little was known about outcomes of this disease due to its rarity. In the past several years, much has been learned about salivary duct carcinoma after publication of outcomes from several ...

journal_title：Oral oncology

authors： Schmitt NC,Kang H,Sharma A

更新日期：2017-11-01 00:00:00

abstract：:Proliferative verrucous leukoplakia (PVL) is a very aggressive form of oral leukoplakia (OL) with high morbidity and mortality rates, hypothesised to be linked to HPV infection. This study aimed to determine the presence of HPV DNA in PVL in comparison with OL, and in relation to social-demographical variables (age, g...

journal_title：Oral oncology

authors： Campisi G,Giovannelli L,Ammatuna P,Capra G,Colella G,Di Liberto C,Gandolfo S,Pentenero M,Carrozzo M,Serpico R,D'Angelo M

更新日期：2004-09-01 00:00:00

abstract：:Immunoreactivity of proliferating cell nuclear antigen (PCNA) was assessed in formalin-fixed, paraffin-embedded sections from human normal parotid gland (N; n = 12), chronic sialadenitis (CS; n = 8), Warthin's tumour (W; n = 10), benign pleomorphic adenoma (BPA; n = 11), mucoepidermoid carcinoma (MEC; n = 14), carcino...

journal_title：Oral oncology

authors： Zhu Q,White FH,Tipoe GL

更新日期：1997-01-01 00:00:00

abstract：:Recently, we reported the preliminary results of a prospective study on the possible premalignant character of oral lichen planus (OLP) and oral lichenoid lesions (OLL). Based on these data it was concluded that there was some but no convincing support for the hypothesis that patients with OLL have an increased risk o...

journal_title：Oral oncology

authors： van der Meij EH,Mast H,van der Waal I

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVES:Human papillomavirus (HPV)-positive tumor status is associated with improved prognosis after disease recurrence in oropharyngeal squamous cell carcinoma (OPSCC). In this study the potential role of survival bias in the relationship between HPV tumor status and the timing of recurrence was evaluated, given co...

journal_title：Oral oncology

authors： Guo T,Rettig E,Fakhry C

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVES:After induction chemotherapy (IC) for laryngeal cancer, Computed Tomography (CT) is used to assess tumor response but lacks rationalized methods for measurement of this response. In T3 laryngeal cancer, remobilization of an initially fixed vocal cord (VC) is a major sign of tumor response. We compared the pe...

journal_title：Oral oncology

authors： Garcia GCTE,Gorphe P,Hartl D,Ammari S,Even C,Tao Y,Balleyguier C,Varoquaux A,Bidault F

更新日期：2019-03-01 00:00:00