The impact of an educational video about radiotherapy and its toxicities in head and neck cancer patients. Evaluation of patients' understanding, anxiety, depression, and quality of life.

Abstract:

OBJECTIVES:Head and neck radiotherapy can cause several toxicities, and its management has important treatment implications. Proper information about treatment is crucial to assist patients by preparing them and enhancing their ability to manage their illness. Thus, this study aimed to verify the impact of an educational video on the improvement of the patient's understanding, satisfaction, quality of life, and influence on their emotional state in different moments of treatment. METHODS:A 10 min video about head and neck radiotherapy and its toxicities was produced. A prospective randomized clinical trial was performed in two groups: a control group (n = 65), which received standard verbal and written information, and an experimental group (n = 65), which received standard information and the video. Appropriated questionnaires (HADS, UW-QOLv4, IRTU, and Post-RTU) were applied in four different moments in order to evaluate patients' understanding, anxiety, depression, and quality of life. RESULTS:The video improved the understanding of treatment and its side effects. Also, the video group reported better awareness about oral health care during the treatment. Osteoradionecrosis and radiation-related caries were the most unknown side effects. On the other hand, the educational video did not modify the patients' anxiety, depression, and quality of life. All patients reported high satisfaction with the video. CONCLUSIONS:Audiovisual tools may improve patients' understanding of radiotherapy and were shown to be a useful tool when used in association with verbal and written information in cancer centers. In addition, information about osteoradionecrosis and radiation-related caries must be reinforced to patients.

journal_name

Oral Oncol

journal_title

Oral oncology

authors

Fernandes DT,Prado-Ribeiro AC,Markman RL,Morais K,Moutinho K,Tonaki JO,Brandão TB,Rivera C,Santos-Silva AR,Lopes MA

doi

10.1016/j.oraloncology.2020.104712

subject

Has Abstract

pub_date

2020-07-01 00:00:00

pages

104712

eissn

1368-8375

issn

1879-0593

pii

S1368-8375(20)30148-2

journal_volume

106

pub_type

杂志文章
  • Aurora kinases are a novel therapeutic target for HPV-positive head and neck cancers.

    abstract:OBJECTIVES:Human papilloma virus (HPV) is the main culprit in cancers of the cervix, penis, anus, skin, eye and head and neck. Current treatments for HPV cancers have not altered survival outcomes for 30 years and there is a significant lack of targeted therapeutic agents in the management of advanced HPV-related HNSCC...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2018.09.006

    authors: Shaikh MH,Idris A,Johnson NW,Fallaha S,Clarke DTW,Martin D,Morgan IM,Gabrielli B,McMillan NAJ

    更新日期:2018-11-01 00:00:00

  • The roles of excision repair cross-complementation group1 in objective response after cisplatin-based concurrent chemoradiotherapy and survival in head and neck cancers: a systematic review and meta-analysis.

    abstract::Our aim of the study was to investigate the precise relationship of repair cross-complementation group 1 (ERCC1) expression and the survival as well as objective response rate to cisplatin-based concurrent chemoradiotherapy (CCRT) and a meta-analysis was conducted to analysis ERCC1's prognostic roles in head and neck ...

    journal_title:Oral oncology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.oraloncology.2015.03.009

    authors: Gao Y,Liu D

    更新日期:2015-06-01 00:00:00

  • A novel evaluation system of metastatic potential of oral squamous cell carcinoma according to the histopathological and histochemical grading.

    abstract::We established a new evaluation system for metastatic potential of oral squamous cell carcinoma (SCC), utilizing a combined examination of histopathological grades of the carcinomas based on cell differentiation and invasive mode according to Yamamoto's criteria, and the cellular expressions of CD44, E-cadherin (E-cad...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/s1368-8375(98)00048-7

    authors: Mori S,Nose M,Morikawa H,Sato A,Saito T,Song ST,Tanda N,Teshima T

    更新日期:1998-11-01 00:00:00

  • Predictors of overall survival in human papillomavirus-associated oropharyngeal cancer using the National Cancer Data Base.

    abstract:OBJECTIVES:This study identifies clinical characteristics associated with HPV-positive oropharynx squamous cell carcinoma (OPSCC) and evaluates predictors of overall survival (OS) in HPV-positive patients undergoing definitive treatment within the National Cancer Data Base (NCDB). MATERIAL AND METHODS:The NCDB was que...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2016.02.011

    authors: Amini A,Jasem J,Jones BL,Robin TP,McDermott JD,Bhatia S,Raben D,Jimeno A,Bowles DW,Karam SD

    更新日期:2016-05-01 00:00:00

  • A novel algorithm for lymph node status prediction of oral cancer before surgery.

    abstract::An algorithm was developed to predict lymph node metastasis in patients with oral squamous cell carcinoma. To improve the diagnostic accuracy of lymph node status, we suggest a criterion for the prediction of lymph node status by combining clinical and molecular information. To develop a model to predict lymph node me...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2011.07.017

    authors: Kim KY,Cha IH

    更新日期:2011-11-01 00:00:00

  • Oral brush biopsy analysis by MALDI-ToF Mass Spectrometry for early cancer diagnosis.

    abstract:OBJECTIVES:Intact cell peptidome profiling (ICPP) with MALDI-ToF Mass Spectrometry holds promise as a non-invasive method to detect head and neck squamous cell carcinoma (HNSCC) objectively, which may significantly improve the early diagnosis of oral cancer. The present study was designed to discriminate between tumour...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2012.08.012

    authors: Maurer K,Eschrich K,Schellenberger W,Bertolini J,Rupf S,Remmerbach TW

    更新日期:2013-02-01 00:00:00

  • Familial aggregation of nasopharyngeal carcinoma in Taiwan.

    abstract:BACKGROUND:The incidence of nasopharyngeal carcinoma (NPC) is higher in Chinese than in Caucasian populations. Genetic, viral, and lifestyle factors may explain these ethnic differences in the incidence of NPC. In the present study, we examined the familial aggregation, heritability, and relative risks (RRs) of NPC usi...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2017.07.020

    authors: Huang SF,Hsiao JH,Young CK,Chien HT,Kuo CF,See LC,Luo SF,Huang LH,Liao CT,Chang TJ

    更新日期:2017-10-01 00:00:00

  • p53-Reactivating small molecules induce apoptosis and enhance chemotherapeutic cytotoxicity in head and neck squamous cell carcinoma.

    abstract::We evaluate whether p53-reactivating (p53RA) small molecules induce p53-dependent apoptosis in head and neck squamous cell carcinoma (HNSCC), a question that has not been previously addressed in head and neck cancer. PRIMA-1, CP-31398, RITA, and nutlin-3 were tested in four human HNSCC cell lines differing in TP53 sta...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2010.10.011

    authors: Roh JL,Kang SK,Minn I,Califano JA,Sidransky D,Koch WM

    更新日期:2011-01-01 00:00:00

  • Socio-economic factors and stage at presentation of head and neck cancer patients in Ottawa, Canada: a logistic regression analysis.

    abstract::To determine if socio-economic status (SES) affects the stage at presentation of head and neck cancer (HNC) patients in Ottawa, Canada. To determine if the method of diagnosis affects the stage at presentation in these patients. We obtained data on SES, method of diagnosis, and stage at presentation for patients prese...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2010.02.010

    authors: Johnson S,Corsten MJ,McDonald JT,Chun J

    更新日期:2010-05-01 00:00:00

  • Current attitudes of head and neck oncologists in the United Kingdom to induction chemotherapy for locally advanced head and neck cancer: a survey of centres participating in a national randomised controlled trial.

    abstract:OBJECTIVES:Induction chemotherapy (IC) followed by chemoradiation (CRT) for locally advanced squamous cell head and neck cancer (SCCHN) remains controversial in the absence of clear evidence to define its role. As part of a prospective, randomised, multicentre study of CRT for stage III/IV laryngeal/hypopharyngeal canc...

    journal_title:Oral oncology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.oraloncology.2013.10.012

    authors: Gujral DM,Piercy D,Morden JP,Emson M,Hall E,Miah AB,Bhide SA,Newbold KL,Harrington KJ,Nutting CM

    更新日期:2014-02-01 00:00:00

  • Glutamine prevents DMBA-induced squamous cell cancer.

    abstract::The etiology of oral squamous cell carcinoma has been linked to environmental carcinogens, such as activated aromatic heterocyclic radicals and epoxides. Our previous work on implantable and 7,12-dimethylbenz[a]anthracene (DMBA)-induced breast cancer showed that oral glutamine (GLN) inhibited tumor growth possibly thr...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2008.04.008

    authors: Lim V,Korourian S,Todorova VK,Kaufmann Y,Klimberg VS

    更新日期:2009-02-01 00:00:00

  • Characterization of four cell lines derived from a human malignant fibrous histiocytoma of the maxillary sinus.

    abstract::We have established four cell lines from a human malignant fibrous histiocytoma. Each cell line had human aneuploid karyotype and DNA aneuploidy. Cells in all lines expressed CD13, CD68 and vimentin but lacked CD11, CD14, CD15, CD16, CD45, HLA class II and other mesenchymal and epithelial markers such as desmin, alpha...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/s1368-8375(01)00004-5

    authors: Mori A,Tagawa T,Kamei T,Murata T,Inui M,Ohse S

    更新日期:2001-09-01 00:00:00

  • Heat shock protein induced TCR gammadelta gene rearrangements in patients with oral cancer.

    abstract::We analyzed the T cell receptor (TCR) gammadelta gene repertoire in peripheral blood and tumor compartment of oral cancer (OC) patients before and after stimulation with heat shock proteins (hsp), which are known ligands for gammadelta T cells. Clonal TCR gamma and delta gene rearrangements in lymphocytes from tumor c...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2004.08.007

    authors: Wadia P,Atre N,Pradhan T,Mistry R,Chiplunkar S

    更新日期:2005-02-01 00:00:00

  • Sentinel lymph node biopsy in clinically N0 T1-T2 staged oral cancer: the Dutch multicenter trial.

    abstract:OBJECTIVES:Results of the Dutch multi-institutional trial on sentinel lymph node (SLN) biopsy in oral cancer. PATIENTS AND METHODS:Patients were consecutively enrolled from 4 institutions, with T1/T2 oral cancer and cN0 neck based on palpation and ultrasound guided fine needle aspiration cytology. Lymphatic mapping co...

    journal_title:Oral oncology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.oraloncology.2014.07.020

    authors: Flach GB,Bloemena E,Klop WM,van Es RJ,Schepman KP,Hoekstra OS,Castelijns JA,Leemans CR,de Bree R

    更新日期:2014-10-01 00:00:00

  • Maté consumption association with upper aerodigestive tract cancers: A systematic review and meta-analysis.

    abstract::Maté is a beverage regularly consumed by Latin American populations. Upper aerodigestive tract (UADT) cancers are frequent in this region and are suspected to be associated with maté consumption. The aim of this systematic review and meta-analysis was to answer a focused question: "Is there an association between maté...

    journal_title:Oral oncology

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.oraloncology.2018.04.023

    authors: Mello FW,Scotti FM,Melo G,Warnakulasuriya S,Guerra ENS,Rivero ERC

    更新日期:2018-07-01 00:00:00

  • Oncological safety of submental island flap for reconstruction of pathologically node-negative and node-positive T1-2 oral squamous cell carcinoma-related defects: A retrospective study and comparison of outcomes.

    abstract:OBJECTIVES:To evaluate the oncological safety and reliability of the submental island flap (SIF) technique in patients with pathologically node-negative (pN0) and node-positive (pN+) T1-2 oral squamous cell carcinoma (OSCC) undergoing surgical tumor resection and concurrent SIF reconstruction. PATIENTS AND METHODS:Ret...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2019.104507

    authors: Wang J,Tan Y,Shen Y,Lv M,Li J,Sun J

    更新日期:2020-03-01 00:00:00

  • Tapered dose versus constant drug exposure to anti-EGFR drugs on head-and-neck cancer xenografts. A comparison between cetuximab and gefitinib.

    abstract::Head-and-neck (H&N) tumor re-growth is clinically observed after arrest of anti-EGFR therapies. In the present study, we compared, for a similar dose exposure to anti-EGFR therapies, constant (CS) with tapered (TS) schedules (i.e. progressive dose reduction) for cetuximab, a mAb, and gefitinib, a TKI. Mice bearing CAL...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2009.11.010

    authors: Bozec A,Formento P,Fischel JL,Etienne-Grimaldi MC,Milano G

    更新日期:2010-03-01 00:00:00

  • Interaction between the immune system and tongue squamous cell carcinoma induced by 4-nitroquinoline N-oxide in mice.

    abstract::Squamous cell carcinoma of the oral cavity (SCC) accounts for 3% of cancers in the western world and 40% of cancers in India. The overall 5-year survival rate is only 50%. Most of the lesions appear intra-orally on the tongue. Results from a previous study demonstrated a significant increase in T and B-lymphocytes und...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2003.08.008

    authors: Gannot G,Buchner A,Keisari Y

    更新日期:2004-03-01 00:00:00

  • Langerhans cell number is a strong and independent prognostic factor for head and neck squamous cell carcinomas.

    abstract:OBJECTIVES:Head and neck squamous cell carcinomas (HNSCCs) exhibit great biological heterogeneity and relatively poor prognosis. Tobacco and alcohol consumption is involved in the cause of the majority of these cancers, but over the last several years, Human Papilloma Virus (HPV) infection has increased specifically in...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2016.08.016

    authors: Kindt N,Descamps G,Seminerio I,Bellier J,Lechien JR,Pottier C,Larsimont D,Journé F,Delvenne P,Saussez S

    更新日期:2016-11-01 00:00:00

  • A prospective randomized controlled trial on the value of prophylactic oral nutritional supplementation in locally advanced nasopharyngeal carcinoma patients receiving chemo-radiotherapy.

    abstract:OBJECTIVES:We investigated the effect of prophylactic oral nutrition supplements (ONS) in locally advanced nasopharyngeal carcinoma patients receiving neoadjuvant chemotherapy and concurrent chemoradiotherapy (CCRT). METHODS:Eligible patients were randomly assigned to an intervention or control group. Patients in the ...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2020.105025

    authors: Huang S,Piao Y,Cao C,Chen J,Sheng W,Shu Z,Hua Y,Jiang F,Hu Q,Chen X,Chen Y

    更新日期:2020-12-01 00:00:00

  • Long-term speech and swallowing function after primary resection and sentinel node biopsy for early oral squamous cell carcinoma.

    abstract:OBJECTIVES:Analysis of long-term speech and swallowing function and subjective quality of life (QOL) after primary resection and sentinel node biopsy (SNB) in patients with early stage (cT1/T2) oral squamous cell carcinomas (OSCC). MATERIAL AND METHODS:Eighty-one consecutive patients treated primarily by transoral res...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2018.12.027

    authors: Romer CAE,Broglie Daeppen MA,Mueller M,Huber GF,Guesewell S,Stoeckli SJ

    更新日期:2019-02-01 00:00:00

  • Malignant melanoma of the oral cavity: diagnosis and treatment experience in a Mexican population.

    abstract::Oral malignant melanoma is uncommon, accounting for 1-8% of all malignant melanomas. All previous papers have reported small numbers of cases or have retrospectively reviewed case reports from the literature. The following case reports concern malignant melanoma of the oral cavity seen at the Instituto Nacional de Can...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/s1368-8375(99)00017-2

    authors: Lopez-Graniel CM,Ochoa-Carrillo FJ,Meneses-García A

    更新日期:1999-07-01 00:00:00

  • Large cell neuroendocrine carcinoma of the head and neck.

    abstract::Large cell neuroendocrine carcinoma is a poorly differentiated neuroendocrine carcinoma that usually occurs in the lung. Although rare in the head and neck, salivary and mucosal subtypes are recognized. This article describes their characteristic light microscopic and immunohistochemical features and highlights the im...

    journal_title:Oral oncology

    pub_type: 杂志文章,评审

    doi:10.1016/j.oraloncology.2011.09.016

    authors: Kusafuka K,Ferlito A,Lewis JS Jr,Woolgar JA,Rinaldo A,Slootweg PJ,Gnepp DR,Devaney KO,Travis WD,Barnes L

    更新日期:2012-03-01 00:00:00

  • Expression of cyclin dependent kinase inhibitor p21waf1/cip1 in premalignant and malignant oral lesions: relationship with p53 status.

    abstract::p21waf1/cip1 protein, an inhibitor of cyclin dependent kinases, is a critical downstream target in the p53-specific pathway of growth control, and can also be induced by p53 independent pathways in relation to terminal differentiation. p21waf1 is also a putative tumour suppressor. Hence, we sought to determine whether...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/s1368-8375(98)00021-9

    authors: Agarwal S,Mathur M,Shukla NK,Ralhan R

    更新日期:1998-09-01 00:00:00

  • Epiregulin promotes migration and invasion of salivary adenoid cystic carcinoma cell line SACC-83 through activation of ERK and Akt.

    abstract::Hematogenous metastasis is one of the most important factors determining the outcome of the patients with salivary adenoid cystic carcinoma (SACC). In the present study, we examined expression profile of genes in SACC cell lines to look for molecules responsible for its unique metastatic trait. A transcriptomic microa...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2008.04.009

    authors: Hu K,Li SL,Gan YH,Wang CY,Yu GY

    更新日期:2009-02-01 00:00:00

  • Cytokeratin expression in precancerous lesions of the human oral cavity.

    abstract::Cytokeratin (CK) expression was studied in buccal mucosa (BM) from 20 leucoplakia and 7 submucous fibrosis patients using sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE), immunoblotting and two-dimensional gel electrophoresis with iso-electric focussing (IEF) as the first dimension. Normal BM exp...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:

    authors: Vaidya MM,Sawant SS,Borges AM,Ogale SB,Bhisey AN

    更新日期:1998-07-01 00:00:00

  • VEGF-C contributes to head and neck squamous cell carcinoma growth and motility.

    abstract::Previous work from our laboratory has demonstrated overexpression of chemokines in head and neck cancer and the utility of targeting these proteins for tumor therapy in a preclinical model. However, the mechanisms involved are unexplored. Through gene expression analysis, we found that expression of vascular endotheli...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2010.02.006

    authors: Benke EM,Ji Y,Patel V,Wang H,Miyazaki H,Yeudall WA

    更新日期:2010-04-01 00:00:00

  • Management of locally advanced oral cancers.

    abstract::Despite easy access to clinical examination majority of oral cancer patients ironically present with locally advanced disease, which is a heterogeneous group that includes all stage III/IV tumours in absence of distant metastasis. The AJCC TNM classification has included all tumours with depth of invasion >1 cm into l...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2020.104662

    authors: Dhar H,Vaish R,D'Cruz AK

    更新日期:2020-06-01 00:00:00

  • Evaluation of the immunogenicity of ALDH(high) human head and neck squamous cell carcinoma cancer stem cells in vitro.

    abstract:OBJECTIVES:To establish the concept that the antigenicity/immunogenicity of ALDH(high) human head and neck squamous cell carcinoma (HNSCC) cancer stem cells (CSC) is distinct from that of ALDH(low) non-CSCs. METHODS:We generated CSC-loaded dendritic cells (DCs) to sensitize autologous peripheral blood T, B lymphocytes...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2016.05.013

    authors: Prince MEP,Zhou L,Moyer JS,Tao H,Lu L,Owen J,Etigen M,Zheng F,Chang AE,Xia J,Wolf G,Wicha MS,Huang S,Ren X,Li Q

    更新日期:2016-08-01 00:00:00

  • Vascular priming enhances chemotherapeutic efficacy against head and neck cancer.

    abstract:PURPOSE:The need to improve chemotherapeutic efficacy against head and neck squamous cell carcinomas (HNSCC) is well recognized. In this study, we investigated the potential of targeting the established tumor vasculature in combination with chemotherapy in head and neck cancer. METHODS:Experimental studies were carrie...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2013.06.011

    authors: Folaron M,Kalmuk J,Lockwood J,Frangou C,Vokes J,Turowski SG,Merzianu M,Rigual NR,Sullivan-Nasca M,Kuriakose MA,Hicks WL Jr,Singh AK,Seshadri M

    更新日期:2013-09-01 00:00:00