Aberrant beta-catenin expression and adenomatous polyposis coli gene mutation in ameloblastoma and odontogenic carcinoma.

abstract：:Systemic chemotherapy is increasingly being used with radiotherapy for the radical treatment of advanced head and neck cancers. Chemotherapy offers modest benefits in the metastatic setting. Platinum containing agents are the most active drugs and form the mainstay of most chemotherapy schedules. In recent years taxan...

journal_title：Oral oncology

authors： Bhide SA,Nutting CM

更新日期：2010-06-01 00:00:00

abstract：:Osteonecrosis of the jaw (ONJ) is an adverse event that has been reported in patients receiving cancer treatment regimens, including bevacizumab, bisphosphonates, and denosumab. We performed a preliminary open label, prospective phase I-II study in patients treated with bisphosphonate to evaluate the treatment effect ...

journal_title：Oral oncology

authors： Ripamonti CI,Cislaghi E,Mariani L,Maniezzo M

更新日期：2011-03-01 00:00:00

abstract：:ED-B fibronectin (ED-B FN), a glycoprotein involved in cell adhesion and migration, is expressed in fetal and neoplastic tissues and absent in their normal counterparts. The aim of this study is to evaluate the expression of this glycoprotein in relation to the histological and clinical data and to determine whether i...

journal_title：Oral oncology

authors： Mhawech P,Dulguerov P,Assaly M,Ares C,Allal AS

更新日期：2005-01-01 00:00:00

abstract：UNLABELLED:Squamous cell carcinoma of the tongue (TSCC) has one of the poorest prognoses of head and neck cancers. This study aims to improve early detection of the disease by identifying salivary biomarkers that can identify a spectrum of patients progressing from high-risk to TSCC. We also examine the mortality of ex...

journal_title：Oral oncology

authors： Korostoff A,Reder L,Masood R,Sinha UK

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:In carefully selected oral cavity cancers, marginal mandibulectomy is an adequate procedure which achieves good disease control adhering to the principle of "doing as little as possible and as much as necessary". METHODOLOGY:This was a retrospective study done by reviewing the medical records of all patient...

journal_title：Oral oncology

authors： Suresh S,Thomas S,Janardhan D,Patil S,George NA,Varghese BT,Iype EM,Rafi M,George CK

更新日期：2019-08-01 00:00:00

abstract：:We hope to establish a new readmission prediction score for patients with head and neck cancer (HNC) after major cancer surgery. A retrospective cohort study was conducted from the clinical and cancer registry data at Kaohsiung Veterans General Hospital. We included the data of patients with newly diagnosed HNC who un...

journal_title：Oral oncology

authors： Yin CH,Kang BH,Liu WS,Pan LF,Chen HM,Lee CC

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVES:After induction chemotherapy (IC) for laryngeal cancer, Computed Tomography (CT) is used to assess tumor response but lacks rationalized methods for measurement of this response. In T3 laryngeal cancer, remobilization of an initially fixed vocal cord (VC) is a major sign of tumor response. We compared the pe...

journal_title：Oral oncology

authors： Garcia GCTE,Gorphe P,Hartl D,Ammari S,Even C,Tao Y,Balleyguier C,Varoquaux A,Bidault F

更新日期：2019-03-01 00:00:00

abstract：:The aim of this study was to systematically review the articles investigating the prognostic value of different microRNAs (miRs) in human head and neck squamous cell carcinoma (HNSCC). Following the guidelines of the Meta-analysis of Observational Studies in Epidemiology group (MOOSE), we performed a broad and sensiti...

journal_title：Oral oncology

authors： Jamali Z,Asl Aminabadi N,Attaran R,Pournagiazar F,Ghertasi Oskouei S,Ahmadpour F

更新日期：2015-04-01 00:00:00

abstract：:The aim of this paper is to assess the reproducibility of a novel binary grading system (high/low risk) of oral epithelial dysplasia and to compare it with the WHO classification 2005. The accuracy of the new system for predicting malignant transformation was also assessed. Ninety-six consecutive oral epithelial dyspl...

journal_title：Oral oncology

authors： Kujan O,Oliver RJ,Khattab A,Roberts SA,Thakker N,Sloan P

更新日期：2006-11-01 00:00:00

abstract：:Cancer of the oropharynx has attracted considerable attention in recent years given: (1) an increasing incidence in selected populations over the past three decades; (2) the discovery of human papillomavirus (HPV) infection as the driver of the increase, as opposed to the traditional risk factors such as tobacco (smok...

journal_title：Oral oncology

authors： Kreimer AR,Chaturvedi AK,Alemany L,Anantharaman D,Bray F,Carrington M,Doorbar J,D'Souza G,Fakhry C,Ferris RL,Gillison M,Neil Hayes D,Hildesheim A,Huang SH,Kowalski LP,Lang Kuhs KA,Lewis J Jr,Lowy DR,Mehanna H,Ness A

更新日期：2020-09-01 00:00:00

abstract：:To describe outcome and prognostic factors in a national Danish series of patients treated for salivary gland carcinoma. From three Danish nation-wide registries and supplementary patient records, 871 patients diagnosed with primary major or minor salivary gland carcinoma in the period from 1990 to 2005 were identifie...

journal_title：Oral oncology

authors： Bjørndal K,Krogdahl A,Therkildsen MH,Overgaard J,Johansen J,Kristensen CA,Homøe P,Sørensen CH,Andersen E,Bundgaard T,Primdahl H,Lambertsen K,Andersen LJ,Godballe C

更新日期：2012-02-01 00:00:00

abstract：:The history of mucositis is as old as radiation- and chemotherapy. Despite being regularly reported and documented as one of the worst side effects of cancer therapy, relatively little was appreciated about the complexities of mucositis' pathogenesis until relatively recently. More frustrating for patients and clinici...

journal_title：Oral oncology

authors： Sonis ST

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:ICIs have expanded treatment options for HNSCC. A minority of the patients respond to these expensive treatments. PATIENTS AND METHODS:This is a single institutional retrospective review on 121 unresectable or metastatic HNSCC patients treated with ICIs. We predicted that inflammatory markers available thro...

journal_title：Oral oncology

authors： Bonomi M,Bhateja P,Issa M,Klamer B,Pan X,Blakaj A,Karivedu V,Mousa L,Mitchell D,Gamez M,Kang S,Seim NB,Old M,Carrau R,Rocco J,Blakaj D

更新日期：2020-11-01 00:00:00

abstract：:Yeasts that are resistant to azole antifungal drugs are increasingly isolated from the mouths of cancer patients suffering from oral fungal infections. Tea tree oil is an agent possessing antimicrobial properties that may prove useful in the prevention and management of infections caused by these organisms. In this st...

journal_title：Oral oncology

authors： Bagg J,Jackson MS,Petrina Sweeney M,Ramage G,Davies AN

更新日期：2006-05-01 00:00:00

abstract：:The hormonal regulation of Na+,K(+)-ATPase enzyme activities and induction of the alpha subunit protein of the enzyme in the human submandibular gland (HSG) were studied by use of cultured HSG cells. We treated HSG cells with thyroid hormone, androgen, mineralocorticoid, and glucocorticoid, singly or in combination. 3...

journal_title：Oral oncology

authors： Kurihara K,Tajima Y,Kawasaki M,Ueha T

更新日期：1999-07-01 00:00:00

abstract：:We assessed the risk factors associated with surgical site infection (SSI) in 697 patients who underwent major oncological surgery for head-and-neck cancer (HNC). SSIs within 30days were classified as incision, space, or leakage/fistula. Preoperative and operative risk factors for SSIs were assessed by univariate and ...

journal_title：Oral oncology

authors： Lee DH,Kim SY,Nam SY,Choi SH,Choi JW,Roh JL

更新日期：2011-06-01 00:00:00

abstract：:Oral cancer has become one of the most aggressive types of cancer, killing 140,000 people worldwide every year. Current treatments for oral cancer include surgery and radiation therapies. These procedures can be very effective; however, they can also drastically decrease the quality of life for survivors. New chemothe...

journal_title：Oral oncology

authors： Retzbach EP,Sheehan SA,Nevel EM,Batra A,Phi T,Nguyen ATP,Kato Y,Baredes S,Fatahzadeh M,Shienbaum AJ,Goldberg GS

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVES:The evaluation of neck lymph node metastasis is critical for predicting survival after head and neck cancer treatment. However, traditional pathological N staging does not completely correlate with survival; the total number of lymph nodes resected during surgery affects staging, and a minimal number of node...

journal_title：Oral oncology

authors： Lin NC,Su IH,Hsu JT,Chang YJ,Tsai KY

更新日期：2021-01-16 00:00:00

abstract：OBJECTIVES:The aim of this study was to investigate the role of the extended Abbé flap in the reconstruction of complex midfacial defects (upper lip, nasal base and medial cheek). We describe our personal experience with this method and present some interesting aspects from the relevant literature. MATERIALS AND METHO...

journal_title：Oral oncology

authors： Mantsopoulos K,Iro H,Constantinidis J

更新日期：2020-01-01 00:00:00

abstract：:Disruption of the homeostatic balance between proliferation and apoptosis is widely believed to contribute to human oral carcinogenesis. Using the Syrian hamster oral cancer model, we examined normal, hyperplastic, dysplastic and malignant oral epithelium for the fraction of apoptotic, proliferating and p12(doc-1) exp...

journal_title：Oral oncology

authors： Kohno Y,Patel V,Kim Y,Tsuji T,Chin BR,Sun M,Bruce Donoff R,Kent R,Wong D,Todd R

更新日期：2002-04-01 00:00:00

abstract：PURPOSE:To assess the relationship between tumor-specific growth rate (TSGR) and oropharyngeal cancer (OPC) outcomes in the HPV era. METHODS/MATERIALS:Primary tumor volume differences between a diagnostic and secondary scan separated ⩾7days without interval treatment were used to estimate TSGR, defined as percent volu...

journal_title：Oral oncology

authors： Murphy CT,Devarajan K,Wang LS,Mehra R,Ridge JA,Fundakowski C,Galloway TJ

更新日期：2015-11-01 00:00:00

abstract：:The mitogen activated serine/threonine kinases (MAPKs) constitute extracellular signal-regulated protein kinases (ERKs), c-Jun N-terminal kinases (JNKs) and p38 MAPK, with an important role in cell proliferation and transformation. Earlier studies from our laboratory had indicated a role for MAPK pathway in oral cance...

journal_title：Oral oncology

authors： Rai R,Mahale A,Saranath D

更新日期：2004-08-01 00:00:00

abstract：:The detection of distant metastases and second primary tumours at the time of initial evaluation changes the prognosis and influences the selection of treatment modality in patients with HNSCC. Until recently chest CT was the single most effective test to screen for distant metastases in HNSCC patients. In this observ...

journal_title：Oral oncology

authors： Brouwer J,Senft A,de Bree R,Comans EF,Golding RP,Castelijns JA,Hoekstra OS,Leemans CR

更新日期：2006-03-01 00:00:00

abstract：:In recent years, studies on the malignant potential of oral lichen planus (OLP) provided clinical evidence that patients affected by OLP have an increased risk to develop oral squamous cell carcinoma (OSCC); nevertheless, controversies still exist as to whether OLP has inherent predisposition to become malignant, or n...

journal_title：Oral oncology

authors： Mignogna MD,Lo Muzio L,Lo Russo L,Fedele S,Ruoppo E,Bucci E

更新日期：2001-04-01 00:00:00

abstract：:This systematic review gives an extensive overview of the current state of functional imaging during (chemo)radiotherapy to predict locoregional control (LRC) and overall survival (OS) for head and neck squamous cell carcinoma. MEDLINE and EMBASE were searched for literature until April 2018 assessing the predictive p...

journal_title：Oral oncology

authors： Martens RM,Noij DP,Ali M,Koopman T,Marcus JT,Vergeer MR,de Vet H,de Jong MC,Leemans CR,Hoekstra OS,de Bree R,de Graaf P,Boellaard R,Castelijns JA

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:To investigate the incidence and clinical features of post-radiation nasopharyngeal necrosis (PRNN), and effectiveness of surgical intervention for its treatment. MATERIALS AND METHODS:Retrospectively, we reviewed 380 NPC patients who underwent high dose radiotherapy (RT) (single RT in 355 and re-RT in 25) fro...

journal_title：Oral oncology

authors： Yang K,Ahn YC,Nam H,Hong SD,Oh D,Noh JM

更新日期：2021-01-23 00:00:00

abstract：:This report describes highlights the dramatic responses seen in patients who were given paclitaxel post progression on immunotherapy. There are multiple mechanisms by which synergistic effects of immunotherapy and chemotherapy occur. Further prospective studies on chemotherapy and immunotherapy are eagerly awaited. ...

journal_title：Oral oncology

authors： Sukari A,Nagasaka M,Abdallah N

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVES:The introduction of intensity modulated radiation therapy (IMRT) has led to new possibilities in the treatment of head and neck cancer (HNC). Limited information is available on how this more advanced radiation technique affects the oral microflora. In a prospective study we assessed the effects of various a...

journal_title：Oral oncology

authors： Schuurhuis JM,Stokman MA,Witjes MJ,Langendijk JA,van Winkelhoff AJ,Vissink A,Spijkervet FK

更新日期：2016-07-01 00:00:00

abstract：:Despite many advances in surgical techniques, technology, radiation therapy, and chemotherapy, survival rates for head and neck cancer (HNCa) have not improved significantly in decades, with many patients being diagnosed at advanced disease stages. Adequate assessment of oral cavity malignancies is critical for approp...

journal_title：Oral oncology

authors： Rumboldt Z,Day TA,Michel M

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVES:Genetic polymorphisms of genes in cell cycle, apoptosis, and inflammation/immune response pathways may control the mechanisms of HPV clearance and HPV escape of immune surveillance and thus may affect both tumor HPV16 status and possibly related outcomes of squamous cell carcinoma of the oropharynx (SCCOP) p...

journal_title：Oral oncology

authors： Feng Y,Li Y,Zhang Y,Zheng H,Li G

更新日期：2016-05-01 00:00:00