Susceptibility to Melaleuca alternifolia (tea tree) oil of yeasts isolated from the mouths of patients with advanced cancer.

Abstract:

:Yeasts that are resistant to azole antifungal drugs are increasingly isolated from the mouths of cancer patients suffering from oral fungal infections. Tea tree oil is an agent possessing antimicrobial properties that may prove useful in the prevention and management of infections caused by these organisms. In this study, 301 yeasts isolated from the mouths of 199 patients suffering from advanced cancer were examined by an in vitro agar dilution assay for susceptibility to tea tree oil. All of the isolates tested were susceptible, including 41 that were known to be resistant to both fluconazole and itraconazole. Clinical studies of tea tree oil as an agent for the prevention and treatment of oral fungal infections in immunocompromised patients merit consideration.

journal_name

Oral Oncol

journal_title

Oral oncology

authors

Bagg J,Jackson MS,Petrina Sweeney M,Ramage G,Davies AN

doi

10.1016/j.oraloncology.2005.10.002

subject

Has Abstract

pub_date

2006-05-01 00:00:00

pages

487-92

issue

5

eissn

1368-8375

issn

1879-0593

pii

S1368-8375(05)00286-1

journal_volume

42

pub_type

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