Abstract:
:The semaphorins belong to a family of proteins originally shown to be important in axon migration and proper central nervous system development. Recent evidence has demonstrated that semaphorins and their receptors are expressed in tissues outside of the nervous system and represent a widespread signaling system that is involved in regulation of motility in many different cell types. This review specifically addresses the effects of the semaphorins on physiological and pathological angiogenesis and will discuss the most recent findings on the role of semaphorins in head and neck squamous cell carcinoma-induced angiogenesis.
journal_name
Oral Oncoljournal_title
Oral oncologyauthors
Sun Q,Nawabi-Ghasimi F,Basile JRdoi
10.1016/j.oraloncology.2007.10.005subject
Has Abstractpub_date
2008-06-01 00:00:00pages
523-31issue
6eissn
1368-8375issn
1879-0593pii
S1368-8375(07)00280-1journal_volume
44pub_type
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