Abstract：
:This report describes highlights the dramatic responses seen in patients who were given paclitaxel post progression on immunotherapy. There are multiple mechanisms by which synergistic effects of immunotherapy and chemotherapy occur. Further prospective studies on chemotherapy and immunotherapy are eagerly awaited.
journal_name
Oral Oncoljournal_title
Oral oncologyauthors
Sukari A,Nagasaka M,Abdallah Ndoi
10.1016/j.oraloncology.2018.03.011subject
Has Abstractpub_date
2018-05-01 00:00:00pages
100-102eissn
1368-8375issn
1879-0593pii
S1368-8375(18)30113-1journal_volume
80pub_type
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ORAL ONCOLOGY文献大全abstract：:The development of locoregional recurrence is the main reason for treatment failure in head and neck squamous cell carcinomas (HNSCC) and the remaining of tumor cells in surgical margins is associated with recurrence. Surgical margins are considered negative based on histologic assessment of the pathological specimen....
journal_title：Oral oncology
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doi：10.1016/j.oraloncology.2011.10.018
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abstract：BACKGROUND:There is a clinical need to improve outcomes for patients with locally advanced squamous cell carcinoma of the head and neck (LA-SCCHN), especially in Human Papilloma Virus (HPV) negative and HPV positive subtypes with a significant history of tobacco use. In animal models bearing SCCHN, Cabazitaxel showed a...
journal_title：Oral oncology
pub_type： 杂志文章
doi：10.1016/j.oraloncology.2017.05.008
更新日期：2017-08-01 00:00:00
abstract：OBJECTIVE:Elective neck dissection (END) for salvage laryngectomy remains controversial due to variability in reported occult nodal metastasis rates and postoperative complications. We performed a meta-analysis to examine the role of END for treatment of the clinically N0 (cN0) neck in the salvage setting. METHODS:A P...
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pub_type： 杂志文章,meta分析
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abstract：:Vocal process granulomas are benign lesions involved in the healing of posterior glottis injuries. Here, we report the results of our conservative treatment of vocal process granulomas. Fifty-three patients with 54 occurrences of granulomas between 1998 and 2007 were enrolled. All patients were observed without surgic...
journal_title：Oral oncology
pub_type： 杂志文章
doi：10.1016/j.oraloncology.2009.01.008
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abstract：OBJECTIVES:A multi-disciplinary team (MDT) is essential in the management of cancer. Head and neck cancer (HNC) is a rare, complex and heterogeneous group of malignancies for which different treatment options are available. However, the potential impact of MDT on the management of HNC has been only poorly evaluated to ...
journal_title：Oral oncology
pub_type： 杂志文章
doi：10.1016/j.oraloncology.2016.01.001
更新日期：2016-03-01 00:00:00
abstract：:Head and neck malignant tumors are classified according to the TNM staging system. The TNM system is a universally accepted, widely used, staging method. Its goals are to help clinicians and researchers to choose from treatment options, to give patients an estimate of their prognosis and to compare results of treatmen...
journal_title：Oral oncology
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abstract：:Histone deacetylases (HDACs) are enzymes that are involved in the remodeling of chromatin and play a key role in the epigenetic regulation of gene expression. In addition, the activity of non-histone proteins can be regulated through HDAC-mediated hypoacetylation. In recent years, inhibition of HDACs has emerged as a ...
journal_title：Oral oncology
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abstract：OBJECTIVES:The staging significance of bone invasion is controversial in oral squamous cell carcinoma (OSCC) cases with tumors measuring 4cm or less according to the American Joint Committee on Cancer (AJCC). Our aim was to retrospectively examine a large group of patients with OSCC to determine the staging significanc...
journal_title：Oral oncology
pub_type： 杂志文章
doi：10.1016/j.oraloncology.2016.01.014
更新日期：2016-04-01 00:00:00
abstract：:The relationship between basic fibroblast growth factor (bFGF), receptors for bFGF and neoangiogenesis was investigated in 51 patients with squamous cell carcinoma of the tongue, 26 of whom had metastatic disease in cervical lymph nodes. Vessels were demonstrated by immunocytochemical labelling for CD34 and expressed ...
journal_title：Oral oncology
pub_type： 杂志文章
doi：10.1016/s1368-8375(00)00032-4
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abstract：:Squamous cell carcinoma of the oral cavity (SCC) accounts for 3% of cancers in the western world and 40% of cancers in India. The overall 5-year survival rate is only 50%. Most of the lesions appear intra-orally on the tongue. Results from a previous study demonstrated a significant increase in T and B-lymphocytes und...
journal_title：Oral oncology
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abstract：OBJECTIVES:There exist no uniform decision criteria for conservative organ preservation treatments in head and neck cancer patients. Even with 18F-FDG-PET/CT after induction chemotherapy patient selection is challenging. This study correlated metabolic tumor response with treatment types and recurrence patterns. MATER...
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doi：10.1016/j.oraloncology.2019.104479
更新日期：2020-01-01 00:00:00
abstract：:We previously showed in human papillomavirus positive oropharyngeal squamous cell carcinoma (HPV+OPSCC) that the presence of intratumoral (IT) PD-L1+ immune cells (ICs) or CD8+ infiltrating ICs are of prognostic value. Here we report the prognostic significance of these immune biomarkers in an independent validation c...
journal_title：Oral oncology
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journal_title：Oral oncology
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abstract：:Oral and pharyngeal cancer (OC) mortality is very low in Greece, especially among men, compared to other European countries. We conducted a case-control study of OC in Athens, and obtained information on tobacco, alcohol use and other potential risk factors and confounding variables for 110 incident cases and 115 hosp...
journal_title：Oral oncology
pub_type： 杂志文章
doi：10.1016/s1368-8375(00)00060-9
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abstract：:This review aims at simplifying the relevant imaging anatomy, guiding the optimal imaging method and highlighting the key imaging findings that influence prognosis and management of oral cavity squamous cell carcinoma (OSCC). Early OSCC can be treated with either surgery alone while advanced cancers are treated with a...
journal_title：Oral oncology
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journal_title：Oral oncology
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journal_title：Oral oncology
pub_type： 杂志文章,评审
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journal_title：Oral oncology
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journal_title：Oral oncology
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更新日期：2014-10-01 00:00:00
abstract：:The selection of housekeeping genes is critical for gene expression studies. To address this issue, four candidate housekeeping genes, including several commonly used ones, were investigated in oral squamous cell carcinoma cell lines. A simple quantitative RT-PCR approach was employed by comparing relative expression ...
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更新日期：2018-05-01 00:00:00
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