Abstract：
:We present four new cases of verruciform xanthoma (VX) in the oral mucosa and review the literature. Clinical, histological, and immunohistochemical features of four new cases of VX were analysed together with cases found in a review of the literature. Expression of CD-68 was studied by immunohistochemistry. Only 162 cases were reported in the oral mucosa. Ninety were males (55.5%) and 72 were females (44.5%). Mean age was 44.9 years. The majority of cases occurred in masticatory mucosa (69.7%). Our cases exhibited papillary or verrucous proliferation of squamous epithelium associated with hyperparakeratosis and with numerous foamy cells confined to the lamina propria papillae. Foamy cells were positive to CD-68 antibody, showing a macrophagic nature. VX is a rare benign lesion, and is probably inflammatory. However, its aetiology and pathological mechanisms remain unknown.
journal_name
Oral Oncoljournal_title
Oral oncologyauthors
Oliveira PT,Jaeger RG,Cabral LA,Carvalho YR,Costa AL,Jaeger MMdoi
10.1016/s1368-8375(00)00068-3subject
Has Abstractpub_date
2001-04-01 00:00:00pages
326-31issue
3eissn
1368-8375issn
1879-0593pii
S1368-8375(00)00068-3journal_volume
37pub_type
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