Abstract：
:Screening populations for the early detection of asymptomatic malignancies and potential malignancies are intuitively attractive strategies to control or reduce the burden of oral cancer on society. Subsequent preventive and/or therapeutic measures must, however, be substantiated by prospective randomized controlled trials (RCT) to markedly improve patient outcomes to reconcile such usages of 'scarce' healthcare resources. This strategic objective is more likely to be achieved by adopting the precedent established by cardiology, where prevention is emphasized over the treatment of occult lesions. For example, the screening identification of individuals at high oral carcinogenic risk will offer potential educational opportunities to change their behaviors, and/or optimize the implementation of contemporary preventive and therapeutic measures for non-compliant individuals. The imperative to substantiate the effectiveness of the screening assays (tests) by prospective RCT also cannot be ignored to safeguard the public against potential false-negative or false-positive diagnoses.
journal_name
Oral Oncoljournal_title
Oral oncologyauthors
Lavelle CL,Scully Cdoi
10.1016/j.oraloncology.2004.04.009subject
Has Abstractpub_date
2005-01-01 00:00:00pages
11-6issue
1eissn
1368-8375issn
1879-0593pii
S1368837504000983journal_volume
41pub_type
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