Assessment of pleomorphic adenomas using MRI and dynamic contrast enhanced MRI.

abstract：OBJECTIVE:A standardized assay to determine the HPV status of head and neck squamous cell carcinoma (HNSCC) specimens has not yet been established, particularly for cytologic samples. The goal of this study was to determine whether the hybrid capture-2 (HC-2) assay, already widely used for the detection of high risk HP...

journal_title：Oral oncology

authors： Smith DF,Maleki Z,Coughlan D,Gooi Z,Akpeng B,Ogawa T,Bishop JA,Frick KD,Agrawal N,Gourin CG,Ha PK,Koch WM,Richmon JD,Westra WH,Pai SI

更新日期：2014-06-01 00:00:00

abstract：:A patient is described who initially presented with pemphigus vulgaris, limited to the oral cavity, and weight loss. Although the various laboratory studies pointed to the diagnosis of paraneoplastic pemphigus (PNP), the underlying neoplasm was not detected until 6 months later, when the patient developed shortness of...

journal_title：Oral oncology

authors： van der Waal RI,Pas HH,Nousari HC,Schulten EA,Jonkman MF,Nieboer C,Stoof TJ,Starink TM,Anhalt GJ

更新日期：2000-07-01 00:00:00

abstract：:Despite easy access to clinical examination majority of oral cancer patients ironically present with locally advanced disease, which is a heterogeneous group that includes all stage III/IV tumours in absence of distant metastasis. The AJCC TNM classification has included all tumours with depth of invasion >1 cm into l...

journal_title：Oral oncology

authors： Dhar H,Vaish R,D'Cruz AK

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Histopathological grading of adenoid cystic carcinoma (ACC) is a controversial issue. It is generally agreed that solid type ACC has a relatively poor prognosis. However, the amount of solid regions within this often mixed type tumor that predicts a poor prognosis is not firmly established. Some authors stip...

journal_title：Oral oncology

authors： van Weert S,van der Waal I,Witte BI,Leemans CR,Bloemena E

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:To assess the relationship between tumor-specific growth rate (TSGR) and oropharyngeal cancer (OPC) outcomes in the HPV era. METHODS/MATERIALS:Primary tumor volume differences between a diagnostic and secondary scan separated ⩾7days without interval treatment were used to estimate TSGR, defined as percent volu...

journal_title：Oral oncology

authors： Murphy CT,Devarajan K,Wang LS,Mehra R,Ridge JA,Fundakowski C,Galloway TJ

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:The increasing occurrence of radiation-induced second primary squamous cell carcinoma of the oral cavity (RISCCO) after radiotherapy for nasopharyngeal carcinoma (NPC) has become a noteworthy complication that can influence long-term survival. This study aimed to analyze the associations of clinicopathologic...

journal_title：Oral oncology

authors： Liu C,Liao L,Wu G,Yan H,Chen X,Wang C,Zheng X,Zeng Z,Zhao Z,Wu D,Liu X

更新日期：2020-06-27 00:00:00

abstract：:The effect of meat and fat in laryngeal carcinogenesis was examined in a case-control study carried out in Uruguay in the time period 1998-1999. One-hundred and forty patients with squamous cell laryngeal carcinoma and 420 hospitalized patients, afflicted with conditions not related with tobacco smoking, alcohol drink...

journal_title：Oral oncology

authors： Oreggia F,De Stefani E,Boffetta P,Brennan P,Deneo-Pellegrini H,Ronco AL

更新日期：2001-02-01 00:00:00

abstract：:Oral leukoplakia is a potentially malignant disorder that will develop into oral cancer at an estimated rate of 1-2% per year. Aim of the present study is to assess the possible predictive value of DNA ploidy for malignant progression of oral leukoplakia. A cohort of 62 leukoplakia patients was studied and their biops...

journal_title：Oral oncology

authors： Bremmer JF,Brakenhoff RH,Broeckaert MA,Beliën JA,Leemans CR,Bloemena E,van der Waal I,Braakhuis BJ

更新日期：2011-10-01 00:00:00

abstract：:To encourage the public to attend and accept oral cancer screening, further understanding is required of the ability of structured information to alter patient knowledge and risk perceptions. Previous work has shown the benefit of written information for those at high risk of oral cancer, especially for tobacco smoker...

journal_title：Oral oncology

authors： Humphris GM,Freeman R,Clarke HM

更新日期：2004-10-01 00:00:00

abstract：:Several reports have indicated that nuclear factor-kappa B (NF-κB) is constitutively activated in a variety of cancer cells including human oral squamous carcinoma cells, and play a key role in their growth and survival. Recent studies report that NF-κB inhibitor, dehydroxymethylepoxyquinomicin (DHMEQ), inhibits proli...

journal_title：Oral oncology

authors： Yasuda A,Kondo S,Nagumo T,Tsukamoto H,Mukudai Y,Umezawa K,Shintani S

更新日期：2011-05-01 00:00:00

abstract：:The present investigation has examined the clinical benefits of tobramycin, polymyxin E and amphotericin therapy in the management of oral mucositis in children undergoing chemotherapy prior to bone marrow transplantation. Tobramycin, polymyxin E, and amphotericin reduced the degree of oral mucositis more than convent...

journal_title：Oral oncology

authors： Bondi E,Baroni C,Prete A,Gatti M,Carrassi A,Lodi G,Porter SR

更新日期：1997-09-01 00:00:00

abstract：:Salivary duct carcinoma (SDC) is a rare, aggressive salivary malignancy that is often diagnosed at an advanced stage. Previously, little was known about outcomes of this disease due to its rarity. In the past several years, much has been learned about salivary duct carcinoma after publication of outcomes from several ...

journal_title：Oral oncology

authors： Schmitt NC,Kang H,Sharma A

更新日期：2017-11-01 00:00:00

abstract：:The aims of this study were to assess a cohort of patients with head and neck squamous cell carcinoma (HNSCC) for: (1) the prevalence of synchronous distant metastases (DM) as detected by the initial staging by using (18)F-FDG PET/CT, (2) the prevalence of metachronous DM, and (3) the validity of published risk factor...

journal_title：Oral oncology

authors： Haerle SK,Schmid DT,Ahmad N,Hany TF,Stoeckli SJ

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:We evaluated the safety of REPLICA, a CAD/CAM-designed patient-specific titanium mandible, in patients with mandibular defects not suitable for reconstruction with traditional techniques. PATIENTS AND METHODS:We performed a cohort study with a composite primary outcome assigned at the end of a 1-year follow-...

journal_title：Oral oncology

authors： Bedogni A,Bettini G,Bedogni G,Menapace G,Sandi A,Michelon F,Di Carlo R,Franco P,Saia G

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVES:Results of the Dutch multi-institutional trial on sentinel lymph node (SLN) biopsy in oral cancer. PATIENTS AND METHODS:Patients were consecutively enrolled from 4 institutions, with T1/T2 oral cancer and cN0 neck based on palpation and ultrasound guided fine needle aspiration cytology. Lymphatic mapping co...

journal_title：Oral oncology

authors： Flach GB,Bloemena E,Klop WM,van Es RJ,Schepman KP,Hoekstra OS,Castelijns JA,Leemans CR,de Bree R

更新日期：2014-10-01 00:00:00

abstract：:The selection of housekeeping genes is critical for gene expression studies. To address this issue, four candidate housekeeping genes, including several commonly used ones, were investigated in oral squamous cell carcinoma cell lines. A simple quantitative RT-PCR approach was employed by comparing relative expression ...

journal_title：Oral oncology

authors： Campos MS,Rodini CO,Pinto-Júnior DS,Nunes FD

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVES:The evaluation of neck lymph node metastasis is critical for predicting survival after head and neck cancer treatment. However, traditional pathological N staging does not completely correlate with survival; the total number of lymph nodes resected during surgery affects staging, and a minimal number of node...

journal_title：Oral oncology

authors： Lin NC,Su IH,Hsu JT,Chang YJ,Tsai KY

更新日期：2021-01-16 00:00:00

abstract：:The p53 pathway is commonly altered during oral and skin carcinogenesis. The lip is a transition tissue between skin and oral mucosa, which in response to UVB exposure also exhibits alterations in the expression of p53 and p53-related genes that could lead to malignant transformation. To assess if the p53-regulated pr...

journal_title：Oral oncology

authors： Martínez A,Brethauer U,Borlando J,Spencer ML,Rojas IG

更新日期：2008-09-01 00:00:00

abstract：:The history of mucositis is as old as radiation- and chemotherapy. Despite being regularly reported and documented as one of the worst side effects of cancer therapy, relatively little was appreciated about the complexities of mucositis' pathogenesis until relatively recently. More frustrating for patients and clinici...

journal_title：Oral oncology

authors： Sonis ST

更新日期：2009-12-01 00:00:00

abstract：:Histone deacetylases (HDACs) are enzymes that are involved in the remodeling of chromatin and play a key role in the epigenetic regulation of gene expression. In addition, the activity of non-histone proteins can be regulated through HDAC-mediated hypoacetylation. In recent years, inhibition of HDACs has emerged as a ...

journal_title：Oral oncology

authors： Iglesias-Linares A,Yañez-Vico RM,González-Moles MA

更新日期：2010-05-01 00:00:00

abstract：:The aim of this study was to define the appropriate fractionation interval between photodynamic therapies (PDTs) for enhanced anti-tumour effects on human oral squamous cell carcinoma (HOSCC). Reoxygenation of HOSCC and the proliferative kinetics of the tumour cells following PDT exposure were evaluated in terms of im...

journal_title：Oral oncology

authors： Togashi H,Uehara M,Ikeda H,Inokuchi T

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVES:The staging significance of bone invasion is controversial in oral squamous cell carcinoma (OSCC) cases with tumors measuring 4cm or less according to the American Joint Committee on Cancer (AJCC). Our aim was to retrospectively examine a large group of patients with OSCC to determine the staging significanc...

journal_title：Oral oncology

authors： Kuk SK,Yoon HJ,Hong SD,Hong SP,Lee JI

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVES:We sought to describe the genetic complexity of 14 UM-SCC oral cavity cancer cell lines that have remained uncharacterized despite being used as model systems for decades. MATERIALS AND METHODS:We performed exome sequencing on 14 oral cavity UM-SCC cell lines and denote the mutational profile of each line. ...

journal_title：Oral oncology

authors： Ludwig ML,Kulkarni A,Birkeland AC,Michmerhuizen NL,Foltin SK,Mann JE,Hoesli RC,Devenport SN,Jewell BM,Shuman AG,Spector ME,Carey TE,Jiang H,Brenner JC

更新日期：2018-12-01 00:00:00

abstract：:Endothelin-1 (ET-1) is a potent vasoconstrictor involved not only in vascular biology but also in carcinogenesis. Results of a study in 2007 suggested salivary ET-1 as a potential biomarker for oral squamous cell carcinoma (OSCC), but a later study showed conflicting results. The purpose of our pilot study was to inve...

journal_title：Oral oncology

authors： Cheng YS,Rees T,Jordan L,Oxford L,O'Brien J,Chen HS,Wong D

更新日期：2011-12-01 00:00:00

abstract：:This review aims at simplifying the relevant imaging anatomy, guiding the optimal imaging method and highlighting the key imaging findings that influence prognosis and management of oral cavity squamous cell carcinoma (OSCC). Early OSCC can be treated with either surgery alone while advanced cancers are treated with a...

journal_title：Oral oncology

authors： Mahajan A,Ahuja A,Sable N,Stambuk HE

更新日期：2020-05-01 00:00:00

abstract：:Because of increased survival rates in childhood cancer, special interest has been focused on the side-effects of the therapy and the quality of life in long-term survivors. Our aim was to investigate craniofacial growth in children who had received different kinds of antineoplastic therapies for solid tumors. A total...

journal_title：Oral oncology

authors： Karsila-Tenovuo S,Jahnukainen K,Peltomäki T,Minn H,Kulmala J,Salmi TT,Rönning O

更新日期：2001-10-01 00:00:00

abstract：PURPOSE:To determine the risk of contralateral nodal failure following ipsilateral radiotherapy in a series of patients with node-positive tonsillar squamous cell carcinoma. METHODS:Retrospective review was used to identify 34 patients with well-lateralized node-positive tonsillar squamous cell carcinoma treated with ...

journal_title：Oral oncology

authors： Gottumukkala S,Pham NL,Sumer B,Myers L,Truelson J,Nedzi L,Khan S,Hughes R,Sher DJ

更新日期：2017-12-01 00:00:00

abstract：:The recently identified single nucleotide polymorphism in the MDM2 promoter (SNP 309) may contribute to the early onset of both sporadic and hereditary malignancies in patients with defective p53. We tested this hypothesis by examining the effects of combined MDM2 polymorphisms and somatic p53 mutations on 351 oral sq...

journal_title：Oral oncology

authors： Huang SF,Chen IH,Liao CT,Wang HM,Liou SH,Hsieh LL

更新日期：2009-01-01 00:00:00

abstract：:Oral cavity and oropharyngeal carcinomas (oral cancer) represents a significant cause of morbidity and mortality. Despite efforts in improving early diagnosis and treatment, the 5-year survival rate of advanced stage of the disease is less than 63%. The field of nanomedicine has offered promising diagnostic and therap...

journal_title：Oral oncology

authors： Marcazzan S,Varoni EM,Blanco E,Lodi G,Ferrari M

更新日期：2018-01-01 00:00:00

abstract：:Over the years, several tumor biomarkers have been suggested to foresee the prognosis oral squamous cell carcinoma (OSCC) patients. Here, we present a systematic review to identify, evaluate and summarize the evidence for OSCC reported markers. Eligible studies were identified through a literature search of MEDLINE/Pu...

journal_title：Oral oncology

authors： Rivera C,Oliveira AK,Costa RAP,De Rossi T,Paes Leme AF

更新日期：2017-09-01 00:00:00