Abstract:
:Salivary duct carcinoma (SDC) is a rare, aggressive salivary malignancy that is often diagnosed at an advanced stage. Previously, little was known about outcomes of this disease due to its rarity. In the past several years, much has been learned about salivary duct carcinoma after publication of outcomes from several large single-institution series and national database searches. Recent studies of genomic alterations have helped elucidate the biology and pathogenesis of this aggressive disease. Here we review outcomes of the disease, effects of treatment, prognostic factors, and genomic alterations in SDC. Studies of targeted therapy and promising future directions are also discussed.
journal_name
Oral Oncoljournal_title
Oral oncologyauthors
Schmitt NC,Kang H,Sharma Adoi
10.1016/j.oraloncology.2017.09.008subject
Has Abstractpub_date
2017-11-01 00:00:00pages
40-48eissn
1368-8375issn
1879-0593pii
S1368-8375(17)30262-2journal_volume
74pub_type
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