Expression of vascular endothelial growth factor-C predicts regional lymph node metastasis in early oral squamous cell carcinoma.

abstract：:Hematogenous metastasis is one of the most important factors determining the outcome of the patients with salivary adenoid cystic carcinoma (SACC). In the present study, we examined expression profile of genes in SACC cell lines to look for molecules responsible for its unique metastatic trait. A transcriptomic microa...

journal_title：Oral oncology

authors： Hu K,Li SL,Gan YH,Wang CY,Yu GY

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVES:Angiotensin I-converting enzyme (ACE), a type I cell surface zinc metallopeptidase, is differentially expressed in several malignancies and plays a role in tumor cell proliferation, tumor cell migration, angiogenesis, and metastatic behavior. We aimed to investigate the effects of ACE gene (rs1799752) varian...

journal_title：Oral oncology

authors： Liu YT,Lin LW,Chen CY,Wang CP,Liu HP,Houng JY,Chung FM,Shieh TY

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVES:The main aim was to investigate the incidence of patient adherence to nutritional tube feeding recommendations in patients with head and neck cancer and to determine patient barriers to meeting tube feeding prescription. MATERIALS AND METHODS:This was an observational study from a randomised controlled tria...

journal_title：Oral oncology

authors： Brown T,Banks M,Hughes BGM,Lin C,Kenny L,Bauer J

更新日期：2017-09-01 00:00:00

abstract：:Oral cancer is a multifactorial disease in which both environmental and genetic factors contribute to the aetiopathogenesis. Oral cancer is the sixth most common cancer worldwide with a higher incidence among Melanesian and South Asian countries. More than 90% of oral cancers are oral squamous cell carcinoma (OSCC). T...

journal_title：Oral oncology

authors： Salahshourifar I,Vincent-Chong VK,Kallarakkal TG,Zain RB

更新日期：2014-05-01 00:00:00

abstract：:Squamous cell carcinoma of the oral cavity (SCC) accounts for 3% of cancers in the western world and 40% of cancers in India. The overall 5-year survival rate is only 50%. Most of the lesions appear intra-orally on the tongue. Results from a previous study demonstrated a significant increase in T and B-lymphocytes und...

journal_title：Oral oncology

authors： Gannot G,Buchner A,Keisari Y

更新日期：2004-03-01 00:00:00

abstract：:Adenoid cystic carcinoma (ACC) of the salivary glands exhibits persistent growth, invasion and metastasis. Chromosome 11q13 amplification is a frequent event associated with tumor progression in a number of carcinomas and is associated with poor prognosis. Two genes within the 11q13 amplicon that are overexpressed as ...

journal_title：Oral oncology

authors： Greer RO Jr,Said S,Shroyer KR,Marileila VG,Weed SA

更新日期：2007-09-01 00:00:00

abstract：:A new photosensitizing agent 5-aminolevulinic acid (ALA)-based photodynamic therapy (PDT) has been demonstrated as a useful method for treatment of superficial neoplastic lesions. The aim of this study was to determine the effects of topically and systemically ALA-based PDT in neoplastic lesions of the oral cavity. Pr...

journal_title：Oral oncology

authors： Ma G,Ikeda H,Inokuchi T,Sano K

更新日期：1999-01-01 00:00:00

abstract：:The hormonal regulation of Na+,K(+)-ATPase enzyme activities and induction of the alpha subunit protein of the enzyme in the human submandibular gland (HSG) were studied by use of cultured HSG cells. We treated HSG cells with thyroid hormone, androgen, mineralocorticoid, and glucocorticoid, singly or in combination. 3...

journal_title：Oral oncology

authors： Kurihara K,Tajima Y,Kawasaki M,Ueha T

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:The use of transoral robotic surgery (TORS) and laser microsurgery (TLM) in the diagnosis and identification of the site of the unknown primary has become increasingly common. This systematic review and meta-analysis aims to assess the use and efficacy of TORS and TLM for this indication. METHOD:Systematic ...

journal_title：Oral oncology

authors： Farooq S,Khandavilli S,Dretzke J,Moore D,Nankivell PC,Sharma N,Almeida JR,Winter SC,Simon C,Paleri V,De M,Siddiq S,Holsinger C,Ferris RL,Mehanna H

更新日期：2019-04-01 00:00:00

abstract：:Bisphosphonates (BP) have been associated with the occurrence of osteonecrosis of the jaw (ONJ), possibly by causing an excessive bone turnover inhibition. However, little in vivo evidence exists to support this theory. The (99m)Tc-medronate scintigrams of patients with skeletal metastases and BP use (n=40) were indiv...

journal_title：Oral oncology

authors： Van den Wyngaert T,Huizing MT,Fossion E,Vermorken JB

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVES:The evaluation of neck lymph node metastasis is critical for predicting survival after head and neck cancer treatment. However, traditional pathological N staging does not completely correlate with survival; the total number of lymph nodes resected during surgery affects staging, and a minimal number of node...

journal_title：Oral oncology

authors： Lin NC,Su IH,Hsu JT,Chang YJ,Tsai KY

更新日期：2021-01-16 00:00:00

abstract：:Early detection of oral cancer is crucial in improving survival rate. Identification and detection of oral potentially malignant disorders (OPMD) allow delivery of interventions to reduce the evolution of these disorders to malignancy. A variety of new and emerging diagnostic aids and adjunctive techniques are current...

journal_title：Oral oncology

authors： Awan KH,Morgan PR,Warnakulasuriya S

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVES:Chemoradiation is the treatment of choice for carcinomas of the pharynx and larynx with imminent loss of organ or function. However, the prognosis after CRT decreases when salvage surgery becomes necessary. Single-cycle induction chemotherapy is therefore performed to identify patients who would benefit more...

journal_title：Oral oncology

authors： Semrau S,Schmidt D,Lell M,Waldfahrer F,Lettmaier S,Kuwert T,Iro H,Fietkau R

更新日期：2013-05-01 00:00:00

abstract：:Lymphatic malformations, traditionally called lymphangiomas, are diseases caused by development errors of the lymphatic system. About 90% of the cases occur within 2years of age, except a few cases which occur in adulthood, and approximately 75% of the lesions are located in the head and neck region. The lesions can g...

journal_title：Oral oncology

authors： Zhou Q,Zheng JW,Mai HM,Luo QF,Fan XD,Su LX,Wang YA,Qin ZP

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVES:Serologic analyses for anti-EBV antibodies used alone usually have low sensitivity for the diagnosis of nasopharyngeal carcinoma (NPC). We assumed that a combined determination of antibodies directed at EBV proteins expressed in both lytic and latent cycles could increase the sensitivity. MATERIALS AND METH...

journal_title：Oral oncology

authors： Ai P,Wang T,Zhang H,Wang Y,Song C,Zhang L,Li Z,Hu H

更新日期：2013-04-01 00:00:00

abstract：:Comorbidity and diagnostic delay are independent prognostic factors in head and neck cancer, most notably in laryngeal cancer. We investigated their inter-relationship and their relative significance in survival of three different head and neck cancers. A population-based retrospective cohort of 221 patients with canc...

journal_title：Oral oncology

authors： Teppo H,Alho OP

更新日期：2009-08-01 00:00:00

abstract：:Autofluorescence examination of oral tissues using the VELscope has been suggested as an adjunctive tool for cancer detection and diagnosis. This study aimed to determine the diagnostic value of VELscope in a large prospective study of 517 patients with oral potentially malignant disorders (OPMD). For the outcome asse...

journal_title：Oral oncology

authors： Shi L,Li C,Shen X,Zhou Z,Liu W,Tang G

更新日期：2019-11-01 00:00:00

abstract：:Pemetrexed has been evaluated as a novel chemotherapeutic for head and neck cancer (HNC). In this review, we examined the efficacy and tolerability of pemetrexed in patients with HNC. Relevant English-language literature was identified via PubMed and a review of published abstracts from the American Society of Clinica...

journal_title：Oral oncology

authors： Argiris A,Pennella E,Koustenis A,Hossain AM,Obasaju CK

更新日期：2013-06-01 00:00:00

abstract：:This systematic review analyses and describes the application and diagnostic accuracy of Artificial Intelligence (AI) methods used for detection and grading of potentially malignant (pre-cancerous) and cancerous head and neck lesions using whole slide images (WSI) of human tissue slides. Electronic databases MEDLINE v...

journal_title：Oral oncology

authors： Mahmood H,Shaban M,Indave BI,Santos-Silva AR,Rajpoot N,Khurram SA

更新日期：2020-11-01 00:00:00

abstract：:Patients with HPV-positive and HPV-negative head and neck squamous cell carcinoma (HNSCC) are significantly different with regard to sociodemographic and behavioral characteristics that clinicians may use to assume tumor HPV status. Machine learning methods were used to evaluate the predictive value of patient charact...

journal_title：Oral oncology

authors： D'Souza G,Zhang HH,D'Souza WD,Meyer RR,Gillison ML

更新日期：2010-02-01 00:00:00

abstract：:Verrucous carcinomas are considered to have poor radioresponsiveness and radiotherapy has been reported to induce anaplastic transformation. Surgery has been considered to be the primary mode of treatment for these tumours. The clinical features, response to radiotherapy, survival and prognostic factors of a group of ...

journal_title：Oral oncology

authors： Jyothirmayi R,Sankaranarayanan R,Varghese C,Jacob R,Nair MK

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVES:This study investigated whether the methylation of ZNF582, PAX1, SOX1, NKX6.1, and PTPRR genes in oral scrapings could be used to detect oral dysplasia and oral cancer and to predict oral cancer recurrence. MATERIALS AND METHODS:Oral scrapings were collected from 65 normal oral mucosa subjects, 107 oral pre...

journal_title：Oral oncology

authors： Cheng SJ,Chang CF,Lee JJ,Chen HM,Wang HJ,Liou YL,Yen C,Chiang CP

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Based on their distinctive histologic and genetic features, the latest WHO classification of soft tissue tumors includes four pathologic variants of rhabdomyosarcoma (RMS): embryonal (ERMS), alveolar (ARMS), spindle cell-sclerosing (SRMS-ScRMS) and pleomorphic RMS. The aim of this study focused on a detailed...

journal_title：Oral oncology

authors： Owosho AA B Ch D,Huang SC Md,Chen S Mbbs,Kashikar S Dds,Estilo CL Dmd,Wolden SL Md,Wexler LH Md,Huryn JM Dds,Antonescu CR Md

更新日期：2016-10-01 00:00:00

abstract：:The aims of this study were to assess a cohort of patients with head and neck squamous cell carcinoma (HNSCC) for: (1) the prevalence of synchronous distant metastases (DM) as detected by the initial staging by using (18)F-FDG PET/CT, (2) the prevalence of metachronous DM, and (3) the validity of published risk factor...

journal_title：Oral oncology

authors： Haerle SK,Schmid DT,Ahmad N,Hany TF,Stoeckli SJ

更新日期：2011-07-01 00:00:00

abstract：:In our previous study, we established an in vitro cellular carcinogenesis model of oral squamous cell carcinoma (OSCC), including a human immortalized oral epithelial cell (HIOEC) and a cancerous cell line (HB96). Microarray analysis showed that the gene encoding Yes-associated protein (YAP) was significantly increase...

journal_title：Oral oncology

authors： Zhang L,Ye DX,Pan HY,Wei KJ,Wang LZ,Wang XD,Shen GF,Zhang ZY

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVES:To characterize specific serious toxicities of reRT with intensity modulated radiation therapy (IMRT) for squamous cell carcinoma of the head and neck (SCCHN) and identify treatment-related predictors of toxicity for patient counseling and decision-making. MATERIALS/METHODS:75 consecutive patients with recu...

journal_title：Oral oncology

authors： Margalit DN,Schoenfeld JD,Rawal B,Haddad RI,Catalano PJ,Goguen LA,Chau NG,Rabinowits G,Lorch JH,Annino DJ,Tishler RB

更新日期：2017-10-01 00:00:00

abstract：PURPOSE:To evaluate a single-institutional experience with the use of re-irradiation for recurrent and new primary cancers of the head and neck. METHODS:The medical charts of 80 consecutive patients who underwent re-irradiation for local-regionally recurrent or second primary head and neck cancer between November 1998...

journal_title：Oral oncology

authors： Velez MA,Veruttipong D,Wang PC,Chin R,Beron P,Abemayor E,St John M,Chen AM

更新日期：2017-04-01 00:00:00

abstract：:The development of locoregional recurrence is the main reason for treatment failure in head and neck squamous cell carcinomas (HNSCC) and the remaining of tumor cells in surgical margins is associated with recurrence. Surgical margins are considered negative based on histologic assessment of the pathological specimen....

journal_title：Oral oncology

authors： de Carvalho AC,Kowalski LP,Campos AH,Soares FA,Carvalho AL,Vettore AL

更新日期：2012-03-01 00:00:00

abstract：:Nasopharyngeal carcinoma is well known to be a viral driven malignancy. Despite high loco-regional control rate with modern radiotherapy, distant metastasis remains as a major threat to the patients highlighting the importance of effective systemic therapy. Recent advances in the understanding of tumor biology, host c...

journal_title：Oral oncology

authors： Chiang AK,Mak NK,Ng WT

更新日期：2014-05-01 00:00:00

abstract：:Oral leukoplakia is the most prevalent and potentially malignant disorder of the oral mucosa. Previous studies have demonstrated that molecular changes of the WWOX gene (WW-domain containing oxidoreductase), a candidate tumor suppressor gene located at 16q23.3-24.1 that spans FRA16D, the second most common fragile sit...

journal_title：Oral oncology

authors： Pimenta FJ,Cordeiro GT,Pimenta LG,Viana MB,Lopes J,Gomez MV,Aldaz CM,De Marco L,Gomez RS

更新日期：2008-08-01 00:00:00