Treatment guidelines of lymphatic malformations of the head and neck.

Abstract:

:Lymphatic malformations, traditionally called lymphangiomas, are diseases caused by development errors of the lymphatic system. About 90% of the cases occur within 2years of age, except a few cases which occur in adulthood, and approximately 75% of the lesions are located in the head and neck region. The lesions can grow rapidly with infection, trauma or bleeding, resulting in disfigurement as well as severe impairment of respiration, swallow and speech. Although lymphatic malformations are benign lesions, they rarely resolve spontaneously, their infiltrating nature coupled with the difficulty in distinguishing involved vital structures of head and neck from adjacent normal tissues makes complete surgical resection even more difficult. The likelihood of postsurgical recurrence and complications is thus higher than other vascular lesions. Surgical resection, sclerotherapy and laser therapy are currently the main treatment modes of lymphatic malformations. Various treatment options have their advantages and disadvantages, the selection of treatment modalities should depend on the patient's individual status and available technology and expertise. The treatment protocol should be individualized, comprehensive as well as sequential in order to obtain the best treatment outcome. Based on published literatures and clinical experiences, we devised the treatment guideline for management of head and neck lymphatic malformations. This protocol will be reviewed and updated periodically to include cutting edge knowledge to provide the best treatment options to benefit our patients.

journal_name

Oral Oncol

journal_title

Oral oncology

authors

Zhou Q,Zheng JW,Mai HM,Luo QF,Fan XD,Su LX,Wang YA,Qin ZP

doi

10.1016/j.oraloncology.2011.08.001

subject

Has Abstract

pub_date

2011-12-01 00:00:00

pages

1105-9

issue

12

eissn

1368-8375

issn

1879-0593

pii

S1368-8375(11)00776-7

journal_volume

47

pub_type

杂志文章,评审
  • Low incidence of H-, K- and N-ras oncogene mutations in cytological specimens of laryngeal tumours.

    abstract::Laryngeal cancer is a rare type of neoplasia, constituting approximately 2% of all human cancers. Mutations of the ras gene family is one of the main activating mechanisms in human cancer. Their involvement in head and neck cancer has been mainly demonstrated at the level of the overexpression whereas ras mutations in...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/s1368-8375(99)00032-9

    authors: Rizos E,Sourvinos G,Arvanitis DA,Velegrakis G,Spandidos DA

    更新日期:1999-11-01 00:00:00

  • Communication of prognosis in head and neck cancer patients; a descriptive qualitative analysis.

    abstract:OBJECTIVES:In shared decision making it is important to adequately, timely and actively involve patients in treatment decisions. Sharing prognostic information can be of key importance. This study describes whether and how prognostic information on life expectancy is included during communication on diagnosis and treat...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2018.07.014

    authors: Dronkers EAC,Hoesseini A,de Boer MF,Offerman MPJ

    更新日期:2018-09-01 00:00:00

  • Anti-tumor activity of dehydroxymethylepoxyquinomicin against human oral squamous cell carcinoma cell lines in vitro and in vivo.

    abstract::Several reports have indicated that nuclear factor-kappa B (NF-κB) is constitutively activated in a variety of cancer cells including human oral squamous carcinoma cells, and play a key role in their growth and survival. Recent studies report that NF-κB inhibitor, dehydroxymethylepoxyquinomicin (DHMEQ), inhibits proli...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2011.03.001

    authors: Yasuda A,Kondo S,Nagumo T,Tsukamoto H,Mukudai Y,Umezawa K,Shintani S

    更新日期:2011-05-01 00:00:00

  • Familial aggregation of nasopharyngeal carcinoma in Taiwan.

    abstract:BACKGROUND:The incidence of nasopharyngeal carcinoma (NPC) is higher in Chinese than in Caucasian populations. Genetic, viral, and lifestyle factors may explain these ethnic differences in the incidence of NPC. In the present study, we examined the familial aggregation, heritability, and relative risks (RRs) of NPC usi...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2017.07.020

    authors: Huang SF,Hsiao JH,Young CK,Chien HT,Kuo CF,See LC,Luo SF,Huang LH,Liao CT,Chang TJ

    更新日期:2017-10-01 00:00:00

  • Shallow whole genome sequencing of adenoid cystic carcinomas of the salivary glands identifies specific chromosomal aberrations related to tumor progression.

    abstract:BACKGROUND AND PURPOSE:Adenoid cystic carcinomas (ACC) are characterized by high rate of local recurrence and late distant metastasis. Chromosomal changes in the evolution from primary tumors to metastatic disease of ACC have not been appointed. Here we investigated the chromosomal alterations of 53 primary tumors from...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2020.104615

    authors: Cordesmeyer R,Laskawi R,Schliephake H,Kauffmann P,Beck J,Bornemann-Kolatzki K,Schütz E,Ströbel P,Kueffer S,Fichtner A,Bremmer F

    更新日期:2020-04-01 00:00:00

  • A phase I study of cabazitaxel in combination with platinum and 5-fluorouracil (PF) in locally advanced squamous cell carcinoma of head and neck (LA-SCCHN).

    abstract:BACKGROUND:There is a clinical need to improve outcomes for patients with locally advanced squamous cell carcinoma of the head and neck (LA-SCCHN), especially in Human Papilloma Virus (HPV) negative and HPV positive subtypes with a significant history of tobacco use. In animal models bearing SCCHN, Cabazitaxel showed a...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2017.05.008

    authors: Camille N,Rozehnal J,Roy E,Uczkowski D,Olson A,Genden E,Teng M,Bakst R,Gupta V,Posner M,Misiukiewicz K

    更新日期:2017-08-01 00:00:00

  • The upregulation of metallothionein-1 expression in areca quid chewing-associated oral squamous cell carcinomas.

    abstract::Metallothioneins (MTs) are a family of low molecular weight, cysteine-rich, inducible, intracellular proteins that bind heavy metals with high affinity. MT-1 is known as a stress-inducible protein and functions as an antioxidant enzyme. Areca quid chewing is a major risk factor in the development and further progressi...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2007.01.019

    authors: Lee SS,Yang SF,Ho YC,Tsai CH,Chang YC

    更新日期:2008-02-01 00:00:00

  • Translational research in nasopharyngeal carcinoma.

    abstract::Nasopharyngeal carcinoma is well known to be a viral driven malignancy. Despite high loco-regional control rate with modern radiotherapy, distant metastasis remains as a major threat to the patients highlighting the importance of effective systemic therapy. Recent advances in the understanding of tumor biology, host c...

    journal_title:Oral oncology

    pub_type: 杂志文章,评审

    doi:10.1016/j.oraloncology.2013.11.005

    authors: Chiang AK,Mak NK,Ng WT

    更新日期:2014-05-01 00:00:00

  • Vascular priming enhances chemotherapeutic efficacy against head and neck cancer.

    abstract:PURPOSE:The need to improve chemotherapeutic efficacy against head and neck squamous cell carcinomas (HNSCC) is well recognized. In this study, we investigated the potential of targeting the established tumor vasculature in combination with chemotherapy in head and neck cancer. METHODS:Experimental studies were carrie...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2013.06.011

    authors: Folaron M,Kalmuk J,Lockwood J,Frangou C,Vokes J,Turowski SG,Merzianu M,Rigual NR,Sullivan-Nasca M,Kuriakose MA,Hicks WL Jr,Singh AK,Seshadri M

    更新日期:2013-09-01 00:00:00

  • Podoplanin expression in oral leukoplakia: tumorigenic role.

    abstract:OBJECTIVES:Recent studies have identified podoplanin, a mucin-type transmembrane glycoprotein, as a biomarker for oral cancer risk in patients with oral leukoplakia (OPL). The aim of this study was to investigate the potential association between podoplanin and the risk of malignant transformation of OPL with epithelia...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2013.02.008

    authors: de Vicente JC,Rodrigo JP,Rodriguez-Santamarta T,Lequerica-Fernández P,Allonca E,García-Pedrero JM

    更新日期:2013-06-01 00:00:00

  • Predictive factors for distant metastasis from oral and oropharyngeal squamous cell carcinoma.

    abstract::The presence of distant metastasis after the initial treatment of head and neck squamous cell carcinoma is not considered a common event and is associated with a poor outcome. The objective of this study was to investigate the prevalence and risk factors associated with the diagnosis of distant metastasis in oral and ...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2005.01.012

    authors: Kowalski LP,Carvalho AL,Martins Priante AV,Magrin J

    更新日期:2005-05-01 00:00:00

  • Modulation of thyroid hormone-dependent Na+,K(+)-ATPase induction in cultured human submandibular gland cell lines, HSG cells.

    abstract::The hormonal regulation of Na+,K(+)-ATPase enzyme activities and induction of the alpha subunit protein of the enzyme in the human submandibular gland (HSG) were studied by use of cultured HSG cells. We treated HSG cells with thyroid hormone, androgen, mineralocorticoid, and glucocorticoid, singly or in combination. 3...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/s1368-8375(98)00124-9

    authors: Kurihara K,Tajima Y,Kawasaki M,Ueha T

    更新日期:1999-07-01 00:00:00

  • Mutation of p53 gene codon 63 in saliva as a molecular marker for oral squamous cell carcinomas.

    abstract::The inactivation of tumor suppressor gene (TSG) is important during multistage carcinogenesis. The p53 TSG is frequently mutated in oral squamous cell carcinomas. These mutations can serve as very specific markers for the presence of tumor cells in a background of normal cells. In this study, 10 oral squamous cell car...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/s1368-8375(00)00005-1

    authors: Liao PH,Chang YC,Huang MF,Tai KW,Chou MY

    更新日期:2000-05-01 00:00:00

  • Histopathological grading of adenoid cystic carcinoma of the head and neck: analysis of currently used grading systems and proposal for a simplified grading scheme.

    abstract:BACKGROUND:Histopathological grading of adenoid cystic carcinoma (ACC) is a controversial issue. It is generally agreed that solid type ACC has a relatively poor prognosis. However, the amount of solid regions within this often mixed type tumor that predicts a poor prognosis is not firmly established. Some authors stip...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2014.10.007

    authors: van Weert S,van der Waal I,Witte BI,Leemans CR,Bloemena E

    更新日期:2015-01-01 00:00:00

  • Comparison of different lymph node staging systems in patients with positive lymph nodes in oral squamous cell carcinoma.

    abstract:OBJECTIVES:The evaluation of neck lymph node metastasis is critical for predicting survival after head and neck cancer treatment. However, traditional pathological N staging does not completely correlate with survival; the total number of lymph nodes resected during surgery affects staging, and a minimal number of node...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2020.105146

    authors: Lin NC,Su IH,Hsu JT,Chang YJ,Tsai KY

    更新日期:2021-01-16 00:00:00

  • Overexpression of human beta-defensin-3 in oral dysplasia: potential role in macrophage trafficking.

    abstract::Human beta-defensins (hBDs) are small, cationic antimicrobial peptides produced by oral and other mucosal epithelia. More recently, hBDs have been shown to regulate adaptive immunity. In this study, we provide new information about the potential role of hBD-3 in the progression of oral cancer. In normal human oral epi...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2008.10.016

    authors: Kawsar HI,Weinberg A,Hirsch SA,Venizelos A,Howell S,Jiang B,Jin G

    更新日期:2009-08-01 00:00:00

  • Cost-effectiveness of low-level laser therapy (LLLT) in head and neck cancer patients receiving concurrent chemoradiation.

    abstract:BACKGROUND:Oral mucositis is a major event increasing treatment costs of head and neck squamous cell carcinoma (HNSCC) patients treated with chemoradiation (CRT). This study was designed to estimate the cost-effectiveness of low-level laser therapy (LLLT) to prevent oral mucositis in HNSCC patients receiving CRT. METH...

    journal_title:Oral oncology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.oraloncology.2015.10.022

    authors: Antunes HS,Schluckebier LF,Herchenhorn D,Small IA,Araújo CM,Viégas CM,Rampini MP,Ferreira EM,Dias FL,Teich V,Teich N,Ferreira CG

    更新日期:2016-01-01 00:00:00

  • Complementary serum test of antibodies to Epstein-Barr virus nuclear antigen-1 and early antigen: a possible alternative for primary screening of nasopharyngeal carcinoma.

    abstract::This hospital-based cohort study evaluated the efficacy of three Epstein-Barr virus (EBV) - associated assays for nasopharyngeal carcinoma (NPC) primary screening and monitoring treatment outcome. Five hundred and seventeen consecutive subjects, including 156 NPC patients, 264 healthy volunteers and 97 patients with h...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2007.10.003

    authors: Chang KP,Hsu CL,Chang YL,Tsang NM,Chen CK,Lee TJ,Tsao KC,Huang CG,Chang YS,Yu JS,Hao SP

    更新日期:2008-08-01 00:00:00

  • Comorbidity in HPV+ and HPV- oropharyngeal cancer patients: A population-based, case-control study.

    abstract:OBJECTIVES:Comorbid conditions impact outcome for patients treated for oropharyngeal squamous cell carcinoma (OPSCC) and serve as competing risk factors for death. The purpose of this study was to examine differences in comorbidities in patients with OPSCC and known HPV-DNA. MATERIAL AND METHODS:We included patients d...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2019.06.035

    authors: Grønhøj C,Kronberg Jakobsen K,Kjær E,Friborg J,von Buchwald C

    更新日期:2019-09-01 00:00:00

  • Exfoliative cytology of normal buccal mucosa to predict the relative risk of cancer in the upper aerodigestive tract using the MN-assay.

    abstract::The high frequency of second or third primary tumors was first explained by Slaughter et al. with the concept of field cancerisation. Another theory postulates micrometastatic lesions as a reason for this phenomenon. The micronuclei (MN)-assay was evaluated to provide evidence for the concept of field cancerisation an...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/s1368-8375(00)00051-8

    authors: Bloching M,Hofmann A,Lautenschläger C,Berghaus A,Grummt T

    更新日期:2000-11-01 00:00:00

  • Evaluation of the immunogenicity of ALDH(high) human head and neck squamous cell carcinoma cancer stem cells in vitro.

    abstract:OBJECTIVES:To establish the concept that the antigenicity/immunogenicity of ALDH(high) human head and neck squamous cell carcinoma (HNSCC) cancer stem cells (CSC) is distinct from that of ALDH(low) non-CSCs. METHODS:We generated CSC-loaded dendritic cells (DCs) to sensitize autologous peripheral blood T, B lymphocytes...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2016.05.013

    authors: Prince MEP,Zhou L,Moyer JS,Tao H,Lu L,Owen J,Etigen M,Zheng F,Chang AE,Xia J,Wolf G,Wicha MS,Huang S,Ren X,Li Q

    更新日期:2016-08-01 00:00:00

  • Programmed death ligand 1 (PD-L1) expression and tumor microenvironment: Implications for patients with oral precancerous lesions.

    abstract:OBJECTIVES:Cancer immunoediting represents a relatively novel concept attempting to explain the process of tumor escape from the host immune system response. Here, we attempted to elucidate the role of programmed death ligand 1 (PD-L1), the tumor microenvironment, and tumor escape mechanisms that allow malignant transf...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2017.03.006

    authors: Yagyuu T,Hatakeyama K,Imada M,Kurihara M,Matsusue Y,Yamamoto K,Obayashi C,Kirita T

    更新日期:2017-05-01 00:00:00

  • Salivary gland cancer stem cells.

    abstract::Emerging evidence suggests the existence of a tumorigenic population of cancer cells that demonstrate stem cell-like properties such as self-renewal and multipotency. These cells, termed cancer stem cells (CSC), are able to both initiate and maintain tumor formation and progression. Studies have shown that CSC are res...

    journal_title:Oral oncology

    pub_type: 杂志文章,评审

    doi:10.1016/j.oraloncology.2013.05.013

    authors: Adams A,Warner K,Nör JE

    更新日期:2013-09-01 00:00:00

  • Characterization of four cell lines derived from a human malignant fibrous histiocytoma of the maxillary sinus.

    abstract::We have established four cell lines from a human malignant fibrous histiocytoma. Each cell line had human aneuploid karyotype and DNA aneuploidy. Cells in all lines expressed CD13, CD68 and vimentin but lacked CD11, CD14, CD15, CD16, CD45, HLA class II and other mesenchymal and epithelial markers such as desmin, alpha...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/s1368-8375(01)00004-5

    authors: Mori A,Tagawa T,Kamei T,Murata T,Inui M,Ohse S

    更新日期:2001-09-01 00:00:00

  • Reprint of Long-term survival and late toxicities of elderly nasopharyngeal carcinoma (NPC) patients treated by high-total- and fractionated-dose simultaneous modulated accelerated radiotherapy with or without chemotherapy.

    abstract:BACKGROUND:To analyse the survival and late toxicities of elderly nasopharyngeal carcinoma (NPC) patients treated by intensity-modulated radiotherapy (IMRT) with the high-total- and fractionated-dose simultaneous modulated accelerated radiation therapy (SMART) boost technique and to identify the effect of concurrent ch...

    journal_title:Oral oncology

    pub_type: 已发布勘误

    doi:10.1016/j.oraloncology.2019.01.005

    authors: Miao J,Wang L,Zhu M,Xiao W,Wu H,Di M,Huang Y,Huang S,Han F,Deng X,Guo X,Zhao C

    更新日期:2019-03-01 00:00:00

  • Management principles of head and neck cancers during pregnancy: a review and case series.

    abstract::Head and neck cancers during pregnancy are rising in incidence. Clinicians need to be aware of the principles of managing these cases. This paper is a review of the literature of head and neck cancers during pregnancy with a short case series of six non-thyroid pregnancy-associated cancers treated by a head and neck o...

    journal_title:Oral oncology

    pub_type: 杂志文章,评审

    doi:10.1016/j.oraloncology.2007.02.003

    authors: Atabo A,Bradley PJ

    更新日期:2008-03-01 00:00:00

  • Prognostic significance of p34cdc2 expression in tongue squamous cell carcinoma.

    abstract::We evaluated the prognostic significance of p34cdc2 expression in 50 tongue squamous cell carcinomas (SCC) using immunohistochemical methods. The p34cdc2 protein was expressed in 33 cases of 50 tumor tissues (66.0%), compared with 15 cases of 42 controlled epithelia (35.7%). The expression of p34cdc2 was significantly...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/s1368-8375(03)00146-5

    authors: Wada S,Yue L,Furuta I

    更新日期:2004-02-01 00:00:00

  • Quality insurance in head and neck cancer multidisciplinary team meetings: A watchful eye on real-life experience.

    abstract:INTRODUCTION:Although Multidisciplinary Team Management (MDT) is integrated in most international head and neck cancer treatment guidelines, its applications and proceedings were rarely described. The present study explores a 6-year real-life experience in a French Comprehensive Cancer Care Center. METHODS:Patients, t...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2019.02.020

    authors: Guy JB,Benna M,Xia Y,Daguenet E,Ben Mrad M,Jmour O,Vial N,Lelonge Y,Fournel P,Prades JM,Vallard A,Magné N

    更新日期:2019-04-01 00:00:00

  • Smoking and alcohol in the etiology of oral cancer: gender-specific risk profiles in the south of Greece.

    abstract::Oral and pharyngeal cancer (OC) mortality is very low in Greece, especially among men, compared to other European countries. We conducted a case-control study of OC in Athens, and obtained information on tobacco, alcohol use and other potential risk factors and confounding variables for 110 incident cases and 115 hosp...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/s1368-8375(00)00060-9

    authors: Zavras AI,Douglass CW,Joshipura K,Wu T,Laskaris G,Petridou E,Dokianakis G,Segas J,Lefantzis D,Nomikos P,Wang YF,Diehl SR

    更新日期:2001-01-01 00:00:00

  • Podoplanin emerges as a functionally relevant oral cancer biomarker and therapeutic target.

    abstract::Oral cancer has become one of the most aggressive types of cancer, killing 140,000 people worldwide every year. Current treatments for oral cancer include surgery and radiation therapies. These procedures can be very effective; however, they can also drastically decrease the quality of life for survivors. New chemothe...

    journal_title:Oral oncology

    pub_type: 杂志文章,评审

    doi:10.1016/j.oraloncology.2018.01.011

    authors: Retzbach EP,Sheehan SA,Nevel EM,Batra A,Phi T,Nguyen ATP,Kato Y,Baredes S,Fatahzadeh M,Shienbaum AJ,Goldberg GS

    更新日期:2018-03-01 00:00:00