Ginkgo biloba extract (EGb 761) induces apoptosis by the activation of caspase-3 in oral cavity cancer cells.

abstract：BACKGROUND:Pioglitazone has shown an inhibitory effect on the growth of cell lines derived from human salivary gland and human oral squamous cell carcinoma. However, whether this effect can be applied to patients with type 2 diabetes mellitus who use pioglitazone for glycemic control remains unanswered. METHODS:The re...

journal_title：Oral oncology

authors： Tseng CH

更新日期：2014-02-01 00:00:00

abstract：:Verrucous carcinomas are considered to have poor radioresponsiveness and radiotherapy has been reported to induce anaplastic transformation. Surgery has been considered to be the primary mode of treatment for these tumours. The clinical features, response to radiotherapy, survival and prognostic factors of a group of ...

journal_title：Oral oncology

authors： Jyothirmayi R,Sankaranarayanan R,Varghese C,Jacob R,Nair MK

更新日期：1997-03-01 00:00:00

abstract：:A patient is described who initially presented with pemphigus vulgaris, limited to the oral cavity, and weight loss. Although the various laboratory studies pointed to the diagnosis of paraneoplastic pemphigus (PNP), the underlying neoplasm was not detected until 6 months later, when the patient developed shortness of...

journal_title：Oral oncology

authors： van der Waal RI,Pas HH,Nousari HC,Schulten EA,Jonkman MF,Nieboer C,Stoof TJ,Starink TM,Anhalt GJ

更新日期：2000-07-01 00:00:00

abstract：PURPOSE:The need to improve chemotherapeutic efficacy against head and neck squamous cell carcinomas (HNSCC) is well recognized. In this study, we investigated the potential of targeting the established tumor vasculature in combination with chemotherapy in head and neck cancer. METHODS:Experimental studies were carrie...

journal_title：Oral oncology

authors： Folaron M,Kalmuk J,Lockwood J,Frangou C,Vokes J,Turowski SG,Merzianu M,Rigual NR,Sullivan-Nasca M,Kuriakose MA,Hicks WL Jr,Singh AK,Seshadri M

更新日期：2013-09-01 00:00:00

abstract：:The aim of this paper is to assess the reproducibility of a novel binary grading system (high/low risk) of oral epithelial dysplasia and to compare it with the WHO classification 2005. The accuracy of the new system for predicting malignant transformation was also assessed. Ninety-six consecutive oral epithelial dyspl...

journal_title：Oral oncology

authors： Kujan O,Oliver RJ,Khattab A,Roberts SA,Thakker N,Sloan P

更新日期：2006-11-01 00:00:00

abstract：:Apicidin acts as a potent histone deacetylases (HDAC) inhibitor and the precise mechanism for its anti-tumor activity in human oral squamous cell carcinoma (OSCC) cells has not been examined. The aim of this study was to evaluate the anti-tumor efficacy of apicidin through apoptosis and autophagy in OSCC cells. Cells ...

journal_title：Oral oncology

authors： Ahn MY,Ahn SG,Yoon JH

更新日期：2011-11-01 00:00:00

abstract：:The etiology of oral squamous cell carcinoma has been linked to environmental carcinogens, such as activated aromatic heterocyclic radicals and epoxides. Our previous work on implantable and 7,12-dimethylbenz[a]anthracene (DMBA)-induced breast cancer showed that oral glutamine (GLN) inhibited tumor growth possibly thr...

journal_title：Oral oncology

authors： Lim V,Korourian S,Todorova VK,Kaufmann Y,Klimberg VS

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVES:We compared the outcomes and survival rates of patients with oral cavity squamous cell carcinoma receiving postoperative conventional radiotherapy (RT) or intensity-modulated radiotherapy (IMRT). MATERIALS AND METHODS:From January 2005 to September 2008, medical records of 131 consecutive patients with oral...

journal_title：Oral oncology

authors： Chen PY,Chen HH,Hsiao JR,Yang MW,Hsueh WT,Tasi ST,Lin FC,Wu YH

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVES/HYPOTHESIS:We review the use of topical chemoprevention agents in patients with oral potentially malignant disorders (PMD). METHODS:A systematic review of studies on topical chemoprevention agents for oral PMD from 1946 to November 2016 was conducted using the MEDLINE database, Embase, and Cochrane Library....

journal_title：Oral oncology

authors： Chau L,Jabara JT,Lai W,Svider PF,Warner BM,Lin HS,Raza SN,Fribley AM

更新日期：2017-04-01 00:00:00

abstract：:Although the amelogenin gene is expressed in ameloblastoma, the precise expression pattern of X and Y amelogenin genes (AMGX, AMGY) in this tumor has not yet been identified. In this study, we analyzed amelogenin gene expression in 19 samples (9 male, 10 female) of oral ameloblastomas by RT-PCR and detect the chromoso...

journal_title：Oral oncology

authors： Tsujigiwa H,Nagatsuka H,Han PP,Gunduz M,Siar CH,Oida S,Nagai N

更新日期：2005-09-01 00:00:00

abstract：:Immunoreactivity of proliferating cell nuclear antigen (PCNA) was assessed in formalin-fixed, paraffin-embedded sections from human normal parotid gland (N; n = 12), chronic sialadenitis (CS; n = 8), Warthin's tumour (W; n = 10), benign pleomorphic adenoma (BPA; n = 11), mucoepidermoid carcinoma (MEC; n = 14), carcino...

journal_title：Oral oncology

authors： Zhu Q,White FH,Tipoe GL

更新日期：1997-01-01 00:00:00

abstract：:A new photosensitizing agent 5-aminolevulinic acid (ALA)-based photodynamic therapy (PDT) has been demonstrated as a useful method for treatment of superficial neoplastic lesions. The aim of this study was to determine the effects of topically and systemically ALA-based PDT in neoplastic lesions of the oral cavity. Pr...

journal_title：Oral oncology

authors： Ma G,Ikeda H,Inokuchi T,Sano K

更新日期：1999-01-01 00:00:00

abstract：:Several lines of evidence demonstrated that the stroma surrounding the tumors plays an important role in the growth and progression of several neoplasms, including oral squamous cell carcinomas (OSCC). We evaluated the presence of myofibroblasts in OSCC and determined whether their presence is associated with clinicop...

journal_title：Oral oncology

authors： Kellermann MG,Sobral LM,da Silva SD,Zecchin KG,Graner E,Lopes MA,Kowalski LP,Coletta RD

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVES:To characterize specific serious toxicities of reRT with intensity modulated radiation therapy (IMRT) for squamous cell carcinoma of the head and neck (SCCHN) and identify treatment-related predictors of toxicity for patient counseling and decision-making. MATERIALS/METHODS:75 consecutive patients with recu...

journal_title：Oral oncology

authors： Margalit DN,Schoenfeld JD,Rawal B,Haddad RI,Catalano PJ,Goguen LA,Chau NG,Rabinowits G,Lorch JH,Annino DJ,Tishler RB

更新日期：2017-10-01 00:00:00

abstract：:We analyzed the T cell receptor (TCR) gammadelta gene repertoire in peripheral blood and tumor compartment of oral cancer (OC) patients before and after stimulation with heat shock proteins (hsp), which are known ligands for gammadelta T cells. Clonal TCR gamma and delta gene rearrangements in lymphocytes from tumor c...

journal_title：Oral oncology

authors： Wadia P,Atre N,Pradhan T,Mistry R,Chiplunkar S

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Several recent studies have shown that incidence of oropharyngeal carcinomas is rising in the Western World. This increase has been attributed to changes in the etiology of oropharyngeal carcinomas with a growing role for infections with Human Papilloma viruses. This nationwide study evaluates and compares t...

journal_title：Oral oncology

authors： van Monsjou HS,Schaapveld M,van den Brekel MW,Balm AJ

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVES:Perineural invasion (PNI) is a common histopathological finding in head and neck squamous cell carcinoma (HNSCC). We aimed to explore the molecular mechanisms involved in PNI and the role of PNI as an aggressive pathological feature. MATERIALS AND METHODS:We used data from The Cancer Genome Atlas (TCGA) to ...

journal_title：Oral oncology

authors： Saidak Z,Clatot F,Chatelain D,Galmiche A

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:Nasopharyngeal carcinoma (NPC) is common in Southeast Asia. Due to the influx of immigrants from this region, the incidence in British Columbia is increasing. Current literature from non-endemic populations encompasses heterogeneous cohorts. This study examines NPC in a North American population, with a high ...

journal_title：Oral oncology

authors： Howlett J,Hamilton S,Ye A,Jewett D,Riou-Green B,Prisman E,Thamboo A

更新日期：2021-01-24 00:00:00

abstract：OBJECTIVES:Head and neck squamous cell carcinomas (HNSCCs) exhibit great biological heterogeneity and relatively poor prognosis. Tobacco and alcohol consumption is involved in the cause of the majority of these cancers, but over the last several years, Human Papilloma Virus (HPV) infection has increased specifically in...

journal_title：Oral oncology

authors： Kindt N,Descamps G,Seminerio I,Bellier J,Lechien JR,Pottier C,Larsimont D,Journé F,Delvenne P,Saussez S

更新日期：2016-11-01 00:00:00

abstract：:Mucoepidermoid carcinoma is the most common malignant tumor in salivary glands and high-grade mucoepidermoid carcinoma is often accompanied with poor prognosis. Many recent research works demonstrated that stromal cell-derived factor-1 (SDF-1) and its receptor CXC chemokine receptor-4 (CXCR4) interaction was critical ...

journal_title：Oral oncology

authors： Wen DS,Zhu XL,Guan SM,Wu YM,Yu LL,Wu JZ

更新日期：2008-06-01 00:00:00

abstract：:Oral mucositis (OM) is a devasting toxicity associated with cytotoxic cancer therapy. Antrum mucosal protein (AMP)-18 and a synthetic peptide surrogate, exhibit cell protective and mitogenic properties in in vitro and in vivo models of gastrointestinal epithelial cell injury. The mucosal barrier-protective effects may...

journal_title：Oral oncology

authors： Chen P,Lingen M,Sonis ST,Walsh-Reitz MM,Toback FG

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVES:examine the cost-effectiveness of routine Calcitonin (Ctn) screening test in the United States. MATERIALS AND METHODS:Markov chain model was developed that compares fine-needle aspiration biopsy (FNAB) with Ctn screening vs. FNAB-only in the evaluation of a thyroid nodule with non-highly suspicious findings...

journal_title：Oral oncology

authors： Al-Qurayshi Z,Kandil E,Randolph GW

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVES:Genetic polymorphisms of genes in cell cycle, apoptosis, and inflammation/immune response pathways may control the mechanisms of HPV clearance and HPV escape of immune surveillance and thus may affect both tumor HPV16 status and possibly related outcomes of squamous cell carcinoma of the oropharynx (SCCOP) p...

journal_title：Oral oncology

authors： Feng Y,Li Y,Zhang Y,Zheng H,Li G

更新日期：2016-05-01 00:00:00

abstract：:To describe outcome and prognostic factors in a national Danish series of patients treated for salivary gland carcinoma. From three Danish nation-wide registries and supplementary patient records, 871 patients diagnosed with primary major or minor salivary gland carcinoma in the period from 1990 to 2005 were identifie...

journal_title：Oral oncology

authors： Bjørndal K,Krogdahl A,Therkildsen MH,Overgaard J,Johansen J,Kristensen CA,Homøe P,Sørensen CH,Andersen E,Bundgaard T,Primdahl H,Lambertsen K,Andersen LJ,Godballe C

更新日期：2012-02-01 00:00:00

abstract：:Large cell neuroendocrine carcinoma is a poorly differentiated neuroendocrine carcinoma that usually occurs in the lung. Although rare in the head and neck, salivary and mucosal subtypes are recognized. This article describes their characteristic light microscopic and immunohistochemical features and highlights the im...

journal_title：Oral oncology

authors： Kusafuka K,Ferlito A,Lewis JS Jr,Woolgar JA,Rinaldo A,Slootweg PJ,Gnepp DR,Devaney KO,Travis WD,Barnes L

更新日期：2012-03-01 00:00:00

abstract：:The aim of this study was to integrate the available data published on odontogenic carcinosarcoma into a comprehensive analysis of their features, treatment and recurrence. An electronic search with no publication date or language restriction was undertaken in March 2018 in the following databases: Medline Ovid, PubMe...

journal_title：Oral oncology

authors： Schuch LF,de Arruda JAA,Silva LVO,Abreu LG,Silva TA,Mesquita RA

更新日期：2018-10-01 00:00:00

abstract：:Keratins have been extensively studied in tissues and cultured keratinocytes but limited information is available on epithelia reconstructed in vitro. The aim of this study was to examine keratin expression in organotypic epithelia with normal (NOK), immortalized (SVpgC2a) and malignant (SqCC/Y1) human buccal cells. O...

journal_title：Oral oncology

authors： Hansson A,Bloor BK,Haig Y,Morgan PR,Ekstrand J,Grafström RC

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVES:We aimed to develop a dual-task model to detect and segment nasopharyngeal carcinoma (NPC) automatically in magnetic resource images (MRI) based on deep learning method, since the differential diagnosis of NPC and atypical benign hyperplasia was difficult and the radiotherapy target contouring of NPC was lab...

journal_title：Oral oncology

authors： Ke L,Deng Y,Xia W,Qiang M,Chen X,Liu K,Jing B,He C,Xie C,Guo X,Lv X,Li C

更新日期：2020-11-01 00:00:00

abstract：:Previous work from our laboratory has demonstrated overexpression of chemokines in head and neck cancer and the utility of targeting these proteins for tumor therapy in a preclinical model. However, the mechanisms involved are unexplored. Through gene expression analysis, we found that expression of vascular endotheli...

journal_title：Oral oncology

authors： Benke EM,Ji Y,Patel V,Wang H,Miyazaki H,Yeudall WA

更新日期：2010-04-01 00:00:00

abstract：:An intravenous pseudotumour at a traumatised site of the buccal mucosa of a 68-year-old woman is described. The lesion was composed of reactive spindle cell proliferation, merging of haphazard bizarre cells and inflammatory elements. Cellular morphology and immunohistochemical profile of proliferating cells reflected ...

journal_title：Oral oncology

authors： Ide F,Shimoyama T,Horie N

更新日期：1998-05-01 00:00:00