Eosinophil ablation and tumor development.

abstract：OBJECTIVES:Prior studies suggest that oxaliplatin is unique among platinum chemotherapy drugs in its ability to enhance anti-tumor immunity, but the immune mechanisms of different platinum chemotherapy drugs have not been previously compared in preclinical models of head and neck squamous cell carcinoma (HNSCC). MATER...

journal_title：Oral oncology

authors： Park SJ,Ye W,Xiao R,Silvin C,Padget M,Hodge JW,Van Waes C,Schmitt NC

更新日期：2019-08-01 00:00:00

abstract：:This systematic review gives an extensive overview of the current state of functional imaging during (chemo)radiotherapy to predict locoregional control (LRC) and overall survival (OS) for head and neck squamous cell carcinoma. MEDLINE and EMBASE were searched for literature until April 2018 assessing the predictive p...

journal_title：Oral oncology

authors： Martens RM,Noij DP,Ali M,Koopman T,Marcus JT,Vergeer MR,de Vet H,de Jong MC,Leemans CR,Hoekstra OS,de Bree R,de Graaf P,Boellaard R,Castelijns JA

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVES:To evaluate the oncological safety and reliability of the submental island flap (SIF) technique in patients with pathologically node-negative (pN0) and node-positive (pN+) T1-2 oral squamous cell carcinoma (OSCC) undergoing surgical tumor resection and concurrent SIF reconstruction. PATIENTS AND METHODS:Ret...

journal_title：Oral oncology

authors： Wang J,Tan Y,Shen Y,Lv M,Li J,Sun J

更新日期：2020-03-01 00:00:00

abstract：:The mitogen activated serine/threonine kinases (MAPKs) constitute extracellular signal-regulated protein kinases (ERKs), c-Jun N-terminal kinases (JNKs) and p38 MAPK, with an important role in cell proliferation and transformation. Earlier studies from our laboratory had indicated a role for MAPK pathway in oral cance...

journal_title：Oral oncology

authors： Rai R,Mahale A,Saranath D

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Histopathological grading of adenoid cystic carcinoma (ACC) is a controversial issue. It is generally agreed that solid type ACC has a relatively poor prognosis. However, the amount of solid regions within this often mixed type tumor that predicts a poor prognosis is not firmly established. Some authors stip...

journal_title：Oral oncology

authors： van Weert S,van der Waal I,Witte BI,Leemans CR,Bloemena E

更新日期：2015-01-01 00:00:00

abstract：:This report describes highlights the dramatic responses seen in patients who were given paclitaxel post progression on immunotherapy. There are multiple mechanisms by which synergistic effects of immunotherapy and chemotherapy occur. Further prospective studies on chemotherapy and immunotherapy are eagerly awaited. ...

journal_title：Oral oncology

authors： Sukari A,Nagasaka M,Abdallah N

更新日期：2018-05-01 00:00:00

abstract：:Recently, we reported the preliminary results of a prospective study on the possible premalignant character of oral lichen planus (OLP) and oral lichenoid lesions (OLL). Based on these data it was concluded that there was some but no convincing support for the hypothesis that patients with OLL have an increased risk o...

journal_title：Oral oncology

authors： van der Meij EH,Mast H,van der Waal I

更新日期：2007-09-01 00:00:00

abstract：:A series of patients with oral squamous cell carcinoma (SCC) observed at the "Regina Elena" Cancer Institute was retrospectively reviewed in order to analyse the risk factors for multiple and second primary tumours (SPTs), their impact on survival and effective measures to control this phenomenon. In a survey of 200 i...

journal_title：Oral oncology

authors： Cianfriglia F,Di Gregorio DA,Manieri A

更新日期：1999-03-01 00:00:00

abstract：:EGFR overexpression in salivary gland carcinomas provides the rational for the investigation of anti-EGFR treatments in recurrent and/or metastatic salivary gland cancers (RMSGCs). The activity of cetuximab in terms of clinical benefit rate (CBR) defined as the occurrence of objective response (CR or PR) or stable dis...

journal_title：Oral oncology

authors： Locati LD,Bossi P,Perrone F,Potepan P,Crippa F,Mariani L,Casieri P,Orsenigo M,Losa M,Bergamini C,Liberatoscioli C,Quattrone P,Calderone RG,Rinaldi G,Pilotti S,Licitra L

更新日期：2009-07-01 00:00:00

abstract：:A patient is described who initially presented with pemphigus vulgaris, limited to the oral cavity, and weight loss. Although the various laboratory studies pointed to the diagnosis of paraneoplastic pemphigus (PNP), the underlying neoplasm was not detected until 6 months later, when the patient developed shortness of...

journal_title：Oral oncology

authors： van der Waal RI,Pas HH,Nousari HC,Schulten EA,Jonkman MF,Nieboer C,Stoof TJ,Starink TM,Anhalt GJ

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Several recent studies have shown that incidence of oropharyngeal carcinomas is rising in the Western World. This increase has been attributed to changes in the etiology of oropharyngeal carcinomas with a growing role for infections with Human Papilloma viruses. This nationwide study evaluates and compares t...

journal_title：Oral oncology

authors： van Monsjou HS,Schaapveld M,van den Brekel MW,Balm AJ

更新日期：2015-10-01 00:00:00

abstract：PURPOSE:The aim of the present study was to evaluate whether texture features extracted from 18F-FDG PET/CT images may provide additional prognostic information in patients with metastatic nasopharyngeal carcinoma (NPC). MATERIALS AND METHOD:We retrospectively examined 52 patients with metastatic NPC who underwent ass...

journal_title：Oral oncology

authors： Lin HC,Chan SC,Cheng NM,Liao CT,Hsu CL,Wang HM,Lin CY,Chang JT,Ng SH,Yang LY,Yen TC

更新日期：2020-05-01 00:00:00

abstract：:Tumor growth is an angiogenesis-dependent process and therapeutic strategies aimed at inhibiting angiogenesis are theoretically attractive. Angiostatin has been shown to potently inhibit endothelial proliferation in vitro and tumor growth in vivo. We now show that a shift in the balance of tumor angiogenesis by gene t...

journal_title：Oral oncology

authors： Matsumoto G,Ohmi Y,Shindo J

更新日期：2001-06-01 00:00:00

abstract：PURPOSE:To determine the risk of contralateral nodal failure following ipsilateral radiotherapy in a series of patients with node-positive tonsillar squamous cell carcinoma. METHODS:Retrospective review was used to identify 34 patients with well-lateralized node-positive tonsillar squamous cell carcinoma treated with ...

journal_title：Oral oncology

authors： Gottumukkala S,Pham NL,Sumer B,Myers L,Truelson J,Nedzi L,Khan S,Hughes R,Sher DJ

更新日期：2017-12-01 00:00:00

abstract：:Chromosomal aberrations are known to have an impact on the initiation and progression of oral squamous cell carcinoma (OSCC), but individual genes involved in OSCC pathogenesis are poorly described. To elucidate the molecular events underlying oral carcinogenesis, a set of primary OSCC were screened for distinct genet...

journal_title：Oral oncology

authors： Freier K,Schwaenen C,Sticht C,Flechtenmacher C,Mühling J,Hofele C,Radlwimmer B,Lichter P,Joos S

更新日期：2007-01-01 00:00:00

abstract：:This study was aimed at estimating the pooled global leukoplakia prevalence using both well-designed studies, which were too few to be representative of the world situation, and less valuable studies. The inverse variance weighting and the random effect methods were used. The latter is based on the principle that if p...

journal_title：Oral oncology

authors： Petti S

更新日期：2003-12-01 00:00:00

abstract：:Specific biomarkers are urgently needed for the detection and progression of oral cancer. The objective of this study was to discover cancer biomarkers from oral epithelium through utilizing high throughput quantitative proteomics approaches. Morphologically malignant, epithelial dysplasia, and adjacent normal epithel...

journal_title：Oral oncology

authors： Xiao H,Langerman A,Zhang Y,Khalid O,Hu S,Cao CX,Lingen MW,Wong DTW

更新日期：2015-11-01 00:00:00

abstract：:This research aims to give a new insight to the relationship between host local immune response and the biological behaviour of the tumor by evaluating of intratumoral natural killer (NK) cells and tumor necrosis factor-alpha (TNFalpha) expressions in oral squamous cell carcinomas. New paraffin sections of the deepest...

journal_title：Oral oncology

authors： Türkseven MR,Oygür T

更新日期：2010-05-01 00:00:00

abstract：:In our previous study, we established an in vitro cellular carcinogenesis model of oral squamous cell carcinoma (OSCC), including a human immortalized oral epithelial cell (HIOEC) and a cancerous cell line (HB96). Microarray analysis showed that the gene encoding Yes-associated protein (YAP) was significantly increase...

journal_title：Oral oncology

authors： Zhang L,Ye DX,Pan HY,Wei KJ,Wang LZ,Wang XD,Shen GF,Zhang ZY

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVES:It is well recognized that oral squamous cell carcinoma (OSCC) cases from Asia that are associated with betel quid chewing are phenotypically distinct to those from Western countries that are predominantly caused by smoking/drinking, but the molecular basis of these differences are largely unknown. The aim o...

journal_title：Oral oncology

authors： Saeed AA,Sims AH,Prime SS,Paterson I,Murray PG,Lopes VR

更新日期：2015-03-01 00:00:00

abstract：UNLABELLED:Despite significant advances in surgical procedures and treatment, long-term prognosis for patients with oral cancer remains poor, with survival rates among the lowest of major cancers. Better methods are desperately needed to identify potential malignancies early when treatments are more effective. OBJECTI...

journal_title：Oral oncology

authors： Abram TJ,Floriano PN,Christodoulides N,James R,Kerr AR,Thornhill MH,Redding SW,Vigneswaran N,Speight PM,Vick J,Murdoch C,Freeman C,Hegarty AM,D'Apice K,Phelan JA,Corby PM,Khouly I,Bouquot J,Demian NM,Weinstock YE,

更新日期：2016-09-01 00:00:00

abstract：:Hyalinizing clear cell carcinoma (HCCC) is a recently described low-grade carcinoma of the salivary glands presenting two main histological features: clear neoplastic cells and prominent hyalinized stroma. Our aim was to characterize the composition of the hyalinized stroma in three cases of HCCC. An immuno-histochemi...

journal_title：Oral oncology

authors： Félix A,Rosa JC,Nunes JF,Fonseca I,Cidadão A,Soares J

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVE:To identify predictive factors of severe long-term toxicity after re-irradiation of recurrent/persistent or second-primary head and neck cancer. METHODS:Outcomes and treatment plans of patients who underwent modern IMRT based re-irradiation to the head and neck from 2008-2015 were reviewed. Co-variables incl...

journal_title：Oral oncology

authors： Lee JY,Suresh K,Nguyen R,Sapir E,Dow JS,Arnould GS,Worden FP,Spector ME,Prince ME,McLean SA,Shuman AG,Malloy KM,Casper K,Bradford CR,Schipper MJ,Eisbruch A

更新日期：2016-09-01 00:00:00

abstract：:The role of the major risk factors, tobacco smoking and alcohol consumption, on trends in intra-oral cancer mortality in England and Wales between 1911 and 1990 was investigated, using lung cancer and liver cirrhosis as surrogate markers for smoking and drinking. Standardised mortality data on lung cancer and liver ci...

journal_title：Oral oncology

authors： Hindle I,Downer MC,Moles DR,Speight PM

更新日期：2000-07-01 00:00:00

abstract：:Maté is a beverage regularly consumed by Latin American populations. Upper aerodigestive tract (UADT) cancers are frequent in this region and are suspected to be associated with maté consumption. The aim of this systematic review and meta-analysis was to answer a focused question: "Is there an association between maté...

journal_title：Oral oncology

authors： Mello FW,Scotti FM,Melo G,Warnakulasuriya S,Guerra ENS,Rivero ERC

更新日期：2018-07-01 00:00:00

abstract：:Squamous cell carcinoma of the oral cavity (SCC) accounts for 3% of cancers in the western world and 40% of cancers in India. The overall 5-year survival rate is only 50%. Most of the lesions appear intra-orally on the tongue. Results from a previous study demonstrated a significant increase in T and B-lymphocytes und...

journal_title：Oral oncology

authors： Gannot G,Buchner A,Keisari Y

更新日期：2004-03-01 00:00:00

abstract：:To encourage the public to attend and accept oral cancer screening, further understanding is required of the ability of structured information to alter patient knowledge and risk perceptions. Previous work has shown the benefit of written information for those at high risk of oral cancer, especially for tobacco smoker...

journal_title：Oral oncology

authors： Humphris GM,Freeman R,Clarke HM

更新日期：2004-10-01 00:00:00

abstract：OBJECTIVES:This study investigated whether the methylation of ZNF582, PAX1, SOX1, NKX6.1, and PTPRR genes in oral scrapings could be used to detect oral dysplasia and oral cancer and to predict oral cancer recurrence. MATERIALS AND METHODS:Oral scrapings were collected from 65 normal oral mucosa subjects, 107 oral pre...

journal_title：Oral oncology

authors： Cheng SJ,Chang CF,Lee JJ,Chen HM,Wang HJ,Liou YL,Yen C,Chiang CP

更新日期：2016-11-01 00:00:00

abstract：:There is relatively little data on salivary gland hypofunction (SGH) in patients with advanced cancer. The aim of the current study was to investigate the epidemiology, aetiology, and clinical features of SGH in this group of patients. The protocol involved completion of standard proforma, completion of a Memorial Sym...

journal_title：Oral oncology

authors： Davies AN,Broadley K,Beighton D

更新日期：2002-10-01 00:00:00

abstract：PURPOSE:To assess the relationship between tumor-specific growth rate (TSGR) and oropharyngeal cancer (OPC) outcomes in the HPV era. METHODS/MATERIALS:Primary tumor volume differences between a diagnostic and secondary scan separated ⩾7days without interval treatment were used to estimate TSGR, defined as percent volu...

journal_title：Oral oncology

authors： Murphy CT,Devarajan K,Wang LS,Mehra R,Ridge JA,Fundakowski C,Galloway TJ

更新日期：2015-11-01 00:00:00