Abstract：
:To define the role of surgical management of lung metastases in ACC. Twenty ACC patients referred to lung metastasectomy were retrospectively reviewed. Twenty-six operations were performed; at the first metastasectomy, a resection with clear margins (R0) was achieved in 11 patients (55%), 3 are alive and well. Four out of 9 patients with residual disease (R2) are still alive. Median survival after metastasectomy was 78 and 52 months for R0 and R2 (p=0.4); median freedom from progression (FFP) in R0 and R2 groups was 30 and 15 months (p=0.2), respectively. A better outcome was obtained for patients with a disease-free interval 36 months and 6 metastases and bilateral involvement were critical in achieving a R0 intervention. Lung metastasectomy provided a prolonged FFP in a high selected subset of patients with ACC. However, if this could be translated into a survival benefit, it is still to be demonstrated.
journal_name
Oral Oncoljournal_title
Oral oncologyauthors
Locati LD,Guzzo M,Bossi P,Massone PP,Conti B,Fumagalli E,Bareggi C,Cantù G,Licitra Ldoi
10.1016/j.oraloncology.2005.04.014subject
Has Abstractpub_date
2005-10-01 00:00:00pages
890-4issue
9eissn
1368-8375issn
1879-0593pii
S1368-8375(05)00129-6journal_volume
41pub_type
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