Periodontitis and oral Cancer-A striking link.

Abstract:

:Oral squamous cell carcinoma (OSCC) has become a major public health problem in the worldwide for its increasing incidence and mortality, especially in younger trends. Risk factors for OSCC apart from alcohol and tobacco use, include poor oral hygiene, inflammation caused by inadequately fitting dentures and other rough teeth surfaces, poor nutrition and some chronic infections caused by fungi, bacteria or viruses. Several studies have also found that the risk of developing OSCC may increase with periodontal disease (PD). In addition to reduce harm caused by tobacco, alcohol and betel quid it seems prudent to take measures to improve oral hygiene in periodontally compromised patients to minimize OSCC risks. This further intensifies the need for oral health education programs and large cohurt studies to edify individuals about the importance of regular oral health maintenance and routine dental care towards the prevention of oral diseases including OSCC.

journal_name

Oral Oncol

journal_title

Oral oncology

authors

Karmakar S,Kar A,Thakur S,Rao VUS

doi

10.1016/j.oraloncology.2020.104630

subject

Has Abstract

pub_date

2020-07-01 00:00:00

pages

104630

eissn

1368-8375

issn

1879-0593

pii

S1368-8375(20)30066-X

journal_volume

106

pub_type

信件
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    更新日期:2011-07-01 00:00:00

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    更新日期:2016-01-01 00:00:00

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    abstract:OBJECTIVES:Prior studies suggest that oxaliplatin is unique among platinum chemotherapy drugs in its ability to enhance anti-tumor immunity, but the immune mechanisms of different platinum chemotherapy drugs have not been previously compared in preclinical models of head and neck squamous cell carcinoma (HNSCC). MATER...

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    authors: Park SJ,Ye W,Xiao R,Silvin C,Padget M,Hodge JW,Van Waes C,Schmitt NC

    更新日期:2019-08-01 00:00:00

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    abstract:OBJECTIVES:To characterize specific serious toxicities of reRT with intensity modulated radiation therapy (IMRT) for squamous cell carcinoma of the head and neck (SCCHN) and identify treatment-related predictors of toxicity for patient counseling and decision-making. MATERIALS/METHODS:75 consecutive patients with recu...

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    authors: Margalit DN,Schoenfeld JD,Rawal B,Haddad RI,Catalano PJ,Goguen LA,Chau NG,Rabinowits G,Lorch JH,Annino DJ,Tishler RB

    更新日期:2017-10-01 00:00:00

  • The roles of microRNAs in the stemness of oral cancer cells.

    abstract::Oral cancer (OC), which is the most common form of head and neck cancers, has one of the lowest (~50%) overall 5-year survival rates. The main reasons for this high mortality rate are diagnosis of OC in advanced stages in most patients and spread to distant organs via lymph node metastasis. Many studies have shown tha...

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    authors: Barlak N,Capik O,Sanli F,Karatas OF

    更新日期:2020-08-19 00:00:00

  • Individualized treatment in stage IVC nasopharyngeal carcinoma.

    abstract::The stage IVC nasopharyngeal carcinoma is a catch-all entity covering minute solitary metastasis to bulky disseminated disease. Prognosis varies greatly within this stage group. A subset of patients with oligometastases may benefit from aggressive local ablative therapy. Meanwhile, in multiple metastatic diseases, cus...

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    pub_type: 杂志文章,评审

    doi:10.1016/j.oraloncology.2014.01.004

    authors: Chan OS,Ngan RK

    更新日期:2014-09-01 00:00:00

  • Smoking and alcohol in the etiology of oral cancer: gender-specific risk profiles in the south of Greece.

    abstract::Oral and pharyngeal cancer (OC) mortality is very low in Greece, especially among men, compared to other European countries. We conducted a case-control study of OC in Athens, and obtained information on tobacco, alcohol use and other potential risk factors and confounding variables for 110 incident cases and 115 hosp...

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    authors: Zavras AI,Douglass CW,Joshipura K,Wu T,Laskaris G,Petridou E,Dokianakis G,Segas J,Lefantzis D,Nomikos P,Wang YF,Diehl SR

    更新日期:2001-01-01 00:00:00

  • Is there an epidemiological link between human papillomavirus DNA and basaloid squamous cell carcinoma of the pharynx?

    abstract::The epidemiological link between human papillomavirus (HPV) DNA and basaloid squamous cell carcinoma (BSCC) of the pharynx was studied. The expression of p53 protein was evaluated by immunohistochemical analysis. The presence of HPV DNA was evaluated by polymerase chain reaction amplification and "in situ" hybridizati...

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    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2006.04.014

    authors: Cabanillas R,Rodrigo JP,Ferlito A,Rinaldo A,Fresno MF,Aguilar C,Alvarez ME,Suárez C

    更新日期:2007-04-01 00:00:00

  • The prognostic significance of age in oropharyngeal squamous cell carcinoma.

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    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2013.12.013

    authors: Ryan Camilon P,Stokes WA,Nguyen SA,Lentsch EJ

    更新日期:2014-05-01 00:00:00

  • Outcomes and prognostic factors in modern era management of major salivary gland cancer.

    abstract:OBJECTIVES:There is a dearth of prospective evidence regarding cancer of the major salivary glands. Outcomes and management of major salivary gland are based largely on retrospective series spanning many decades and changes in surgical, radiation, imaging and systemic therapy strategies and technique. We sought to repo...

    journal_title:Oral oncology

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    doi:10.1016/j.oraloncology.2015.05.005

    authors: Jegadeesh N,Liu Y,Prabhu RS,Magliocca KR,Marcus DM,Higgins KA,Vainshtein JM,Trad Wadsworth J,Beitler JJ

    更新日期:2015-08-01 00:00:00

  • Treatment guidelines and patterns of care in oral cavity squamous cell carcinoma: Primary surgical resection vs. nonsurgical treatment.

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    doi:10.1016/j.oraloncology.2017.06.013

    authors: Fujiwara RJT,Burtness B,Husain ZA,Judson BL,Bhatia A,Sasaki CT,Yarbrough WG,Mehra S

    更新日期:2017-08-01 00:00:00

  • Orbital outcomes after orbit-sparing surgery and free flap reconstruction.

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    authors: Philips R,Topf MC,Graf A,Krein H,Heffelfinger R,Luginbuhl A,Curry J

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    abstract::Despite many advances in surgical techniques, technology, radiation therapy, and chemotherapy, survival rates for head and neck cancer (HNCa) have not improved significantly in decades, with many patients being diagnosed at advanced disease stages. Adequate assessment of oral cavity malignancies is critical for approp...

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    doi:10.1016/j.oraloncology.2006.01.010

    authors: Rumboldt Z,Day TA,Michel M

    更新日期:2006-10-01 00:00:00

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    authors: Guo T,Rettig E,Fakhry C

    更新日期:2016-01-01 00:00:00

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    更新日期:2011-10-01 00:00:00

  • Interventions for the management of radiotherapy-induced xerostomia and hyposalivation: A systematic review and meta-analysis.

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    authors: Mercadante V,Al Hamad A,Lodi G,Porter S,Fedele S

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  • The role of salivary cytokine biomarkers in tongue cancer invasion and mortality.

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    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2004.09.013

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    更新日期:2005-04-01 00:00:00

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    abstract:OBJECTIVE:To identify predictive factors of severe long-term toxicity after re-irradiation of recurrent/persistent or second-primary head and neck cancer. METHODS:Outcomes and treatment plans of patients who underwent modern IMRT based re-irradiation to the head and neck from 2008-2015 were reviewed. Co-variables incl...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2016.06.017

    authors: Lee JY,Suresh K,Nguyen R,Sapir E,Dow JS,Arnould GS,Worden FP,Spector ME,Prince ME,McLean SA,Shuman AG,Malloy KM,Casper K,Bradford CR,Schipper MJ,Eisbruch A

    更新日期:2016-09-01 00:00:00

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    journal_title:Oral oncology

    pub_type: 杂志文章,评审

    doi:10.1016/j.oraloncology.2015.02.092

    authors: Martinez-Useros J,Garcia-Foncillas J

    更新日期:2015-05-01 00:00:00

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    abstract::Indole-3-carbinol (I3C), a naturally occurring phytochemical found in cruciferous vegetables, has received much attention due to its translational potential in cancer prevention and therapy. In this study, we investigated the antitumor effects of OSU-A9, a structurally optimized I3C derivative, in a panel of oral squa...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2010.08.005

    authors: Weng JR,Bai LY,Omar HA,Sargeant AM,Yeh CT,Chen YY,Tsai MH,Chiu CF

    更新日期:2010-10-01 00:00:00

  • Shallow whole genome sequencing of adenoid cystic carcinomas of the salivary glands identifies specific chromosomal aberrations related to tumor progression.

    abstract:BACKGROUND AND PURPOSE:Adenoid cystic carcinomas (ACC) are characterized by high rate of local recurrence and late distant metastasis. Chromosomal changes in the evolution from primary tumors to metastatic disease of ACC have not been appointed. Here we investigated the chromosomal alterations of 53 primary tumors from...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2020.104615

    authors: Cordesmeyer R,Laskawi R,Schliephake H,Kauffmann P,Beck J,Bornemann-Kolatzki K,Schütz E,Ströbel P,Kueffer S,Fichtner A,Bremmer F

    更新日期:2020-04-01 00:00:00

  • Gene expression profiling reveals biological pathways responsible for phenotypic heterogeneity between UK and Sri Lankan oral squamous cell carcinomas.

    abstract:OBJECTIVES:It is well recognized that oral squamous cell carcinoma (OSCC) cases from Asia that are associated with betel quid chewing are phenotypically distinct to those from Western countries that are predominantly caused by smoking/drinking, but the molecular basis of these differences are largely unknown. The aim o...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/j.oraloncology.2014.12.004

    authors: Saeed AA,Sims AH,Prime SS,Paterson I,Murray PG,Lopes VR

    更新日期:2015-03-01 00:00:00

  • Multiple primary tumours in patients with oral squamous cell carcinoma.

    abstract::A series of patients with oral squamous cell carcinoma (SCC) observed at the "Regina Elena" Cancer Institute was retrospectively reviewed in order to analyse the risk factors for multiple and second primary tumours (SPTs), their impact on survival and effective measures to control this phenomenon. In a survey of 200 i...

    journal_title:Oral oncology

    pub_type: 杂志文章

    doi:10.1016/s1368-8375(98)00105-5

    authors: Cianfriglia F,Di Gregorio DA,Manieri A

    更新日期:1999-03-01 00:00:00