Abstract:
:Preoperative elevation of serum C-reactive protein (CRP) has been demonstrated as a prognostic indicator in oesophageal, gastric and colorectal cancer. This study was designed to establish if elevated preoperative levels of serum CRP could predict the prognosis of patients treated with primary surgery for oral squamous cell carcinoma (SCC). Sixty patients with oral SCC who were treated by primary surgery and microvascular free flap reconstruction, were included in the study. The relation between preoperative levels of serum CRP, clinicopathological features and patient prognosis was determined. This study showed using bivariate analysis (p=0.003) and multivariate analysis (p<0.001) that a raised preoperative CRP was associated with worse overall survival. Tumour size and stage when combined with CRP levels increases the predictive power of this indicator.
journal_name
Oral Oncoljournal_title
Oral oncologyauthors
Khandavilli SD,Ceallaigh PO,Lloyd CJ,Whitaker Rdoi
10.1016/j.oraloncology.2009.03.015subject
Has Abstractpub_date
2009-10-01 00:00:00pages
912-4issue
10eissn
1368-8375issn
1879-0593pii
S1368-8375(09)00089-Xjournal_volume
45pub_type
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