Individualized treatment in stage IVC nasopharyngeal carcinoma.

Abstract:

:The stage IVC nasopharyngeal carcinoma is a catch-all entity covering minute solitary metastasis to bulky disseminated disease. Prognosis varies greatly within this stage group. A subset of patients with oligometastases may benefit from aggressive local ablative therapy. Meanwhile, in multiple metastatic diseases, customizing conventional cytotoxics basing on individual tumor characteristics and previous chemotherapy responses can be a new direction to improve therapeutic results. Prognostic models built on clinical features and genomic profiles can be utilized to stratify different risk groups and tailor therapy schemes.

journal_name

Oral Oncol

journal_title

Oral oncology

authors

Chan OS,Ngan RK

doi

10.1016/j.oraloncology.2014.01.004

subject

Has Abstract

pub_date

2014-09-01 00:00:00

pages

791-7

issue

9

eissn

1368-8375

issn

1879-0593

pii

S1368-8375(14)00008-6

journal_volume

50

pub_type

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