Spindle-cell lipoma of the cheek: a case report.


:Spindle-cell lipoma (SCL) is a distinct histological variant of lipoma. Clinically, it appears as a solitary, subcutaneous, circumscribed lesion. SCL accounts for about 1.5% of all adipocytic tumours. Only nine cases of intraoral SCL were found in the literature. Microscopically, mature adipocytes and spindle cells are immersed in a myxoid stroma. SCL needs only local excision, and it does not recur.


Oral Oncol


Oral oncology


Piattelli A,Rubini C,Fioroni M,Iezzi G




Has Abstract


2000-09-01 00:00:00














  • Topical agents for oral cancer chemoprevention: A systematic review of the literature.

    abstract:OBJECTIVES/HYPOTHESIS:We review the use of topical chemoprevention agents in patients with oral potentially malignant disorders (PMD). METHODS:A systematic review of studies on topical chemoprevention agents for oral PMD from 1946 to November 2016 was conducted using the MEDLINE database, Embase, and Cochrane Library....

    journal_title:Oral oncology

    pub_type: 杂志文章,评审


    authors: Chau L,Jabara JT,Lai W,Svider PF,Warner BM,Lin HS,Raza SN,Fribley AM

    更新日期:2017-04-01 00:00:00

  • Confocal laser endomicroscopy for non-invasive head and neck cancer imaging: a comprehensive review.

    abstract::Histological assessment is an essential tool in the diagnosis and guidance of the treatment of various diseases, in particular cancer, of the head and neck. Recent major advances in optical imaging techniques have made it possible to acquire high-resolution in vivo images at the cellular scale. Confocal endomicroscopy...

    journal_title:Oral oncology

    pub_type: 杂志文章,评审


    authors: Abbaci M,Breuskin I,Casiraghi O,De Leeuw F,Ferchiou M,Temam S,Laplace-Builhé C

    更新日期:2014-08-01 00:00:00

  • Clinical guidelines in early detection of oral squamous cell carcinoma arising in oral lichen planus: a 5-year experience.

    abstract::In recent years, studies on the malignant potential of oral lichen planus (OLP) provided clinical evidence that patients affected by OLP have an increased risk to develop oral squamous cell carcinoma (OSCC); nevertheless, controversies still exist as to whether OLP has inherent predisposition to become malignant, or n...

    journal_title:Oral oncology

    pub_type: 杂志文章


    authors: Mignogna MD,Lo Muzio L,Lo Russo L,Fedele S,Ruoppo E,Bucci E

    更新日期:2001-04-01 00:00:00

  • Treatment and outcomes of nasopharyngeal carcinoma in a unique non-endemic population.

    abstract:OBJECTIVE:Nasopharyngeal carcinoma (NPC) is common in Southeast Asia. Due to the influx of immigrants from this region, the incidence in British Columbia is increasing. Current literature from non-endemic populations encompasses heterogeneous cohorts. This study examines NPC in a North American population, with a high ...

    journal_title:Oral oncology

    pub_type: 杂志文章


    authors: Howlett J,Hamilton S,Ye A,Jewett D,Riou-Green B,Prisman E,Thamboo A

    更新日期:2021-01-24 00:00:00

  • Dysplasia/neoplasia surveillance in oral lichen planus patients: a description of clinical criteria adopted at a single centre and their impact on prognosis.

    abstract::The concept of dysplasia/neoplasia surveillance has been applied to long-standing conditions associated with an increased risk of cancer. Although still controversial, periodic direct clinical examination as well as endoscopic techniques are currently performed in patients with inflammatory bowel diseases, Barrett's e...

    journal_title:Oral oncology

    pub_type: 杂志文章


    authors: Mignogna MD,Fedele S,Lo Russo L

    更新日期:2006-09-01 00:00:00

  • Prognostic role of programmed death ligand 1 (PD-L1) and the immune microenvironment in laryngeal carcinoma.

    abstract:OBJECTIVES:The immune system is crucial in the evolution of head and neck cancer. Programmed cell death ligand 1 (PD-L1) seems to rely on close relations between neoplastic cells and immune cells in the tumor microenvironment. The main aim of this study was to apply univariate/multivariate analysis to investigate the p...

    journal_title:Oral oncology

    pub_type: 杂志文章


    authors: Alessandrini L,Franz L,Ottaviano G,Ghi MG,Lanza C,Blandamura S,Marioni G

    更新日期:2020-09-01 00:00:00

  • Histopathological grading of adenoid cystic carcinoma of the head and neck: analysis of currently used grading systems and proposal for a simplified grading scheme.

    abstract:BACKGROUND:Histopathological grading of adenoid cystic carcinoma (ACC) is a controversial issue. It is generally agreed that solid type ACC has a relatively poor prognosis. However, the amount of solid regions within this often mixed type tumor that predicts a poor prognosis is not firmly established. Some authors stip...

    journal_title:Oral oncology

    pub_type: 杂志文章


    authors: van Weert S,van der Waal I,Witte BI,Leemans CR,Bloemena E

    更新日期:2015-01-01 00:00:00

  • The possible premalignant character of oral lichen planus and oral lichenoid lesions: a prospective five-year follow-up study of 192 patients.

    abstract::Recently, we reported the preliminary results of a prospective study on the possible premalignant character of oral lichen planus (OLP) and oral lichenoid lesions (OLL). Based on these data it was concluded that there was some but no convincing support for the hypothesis that patients with OLL have an increased risk o...

    journal_title:Oral oncology

    pub_type: 杂志文章,评审


    authors: van der Meij EH,Mast H,van der Waal I

    更新日期:2007-09-01 00:00:00

  • Risk and survival of patients with medullary thyroid cancer: National perspective.

    abstract:BACKGROUND:Medullary thyroid carcinoma (MTC) is a neuroendocrine tumor account for 1-2% of thyroid cancer. In this study, we aim to examine the characteristics and survival of patients with MTC. METHODS:A retrospective cohort study utilizing the National Cancer Data Base, 2004-2014. The study population included adult...

    journal_title:Oral oncology

    pub_type: 杂志文章


    authors: Al-Qurayshi Z,Khadra H,Chang K,Pagedar N,Randolph GW,Kandil E

    更新日期:2018-08-01 00:00:00

  • Risk-based stratification in head and neck mucosal melanoma.

    abstract:BACKGROUND:Head and neck mucosal melanoma (HNMM) is a rare and aggressive disease with a high metastatic potential. Two staging systems are currently available: one specific to HNMM (mmTNM) and one specific to primary tumour sites (sccTNM). Our main objective was to assess the prognostic value of both of these classifi...

    journal_title:Oral oncology

    pub_type: 杂志文章


    authors: Moya-Plana A,Mangin D,Dercle L,Taouachi R,Casiraghi O,Ammari S,Nguyen F,Temam S,Robert C,Gorphe P

    更新日期:2019-10-01 00:00:00

  • Polymorphism of angiotensin I-converting enzyme gene is related to oral cancer and lymph node metastasis in male betel quid chewers.

    abstract:OBJECTIVES:Angiotensin I-converting enzyme (ACE), a type I cell surface zinc metallopeptidase, is differentially expressed in several malignancies and plays a role in tumor cell proliferation, tumor cell migration, angiogenesis, and metastatic behavior. We aimed to investigate the effects of ACE gene (rs1799752) varian...

    journal_title:Oral oncology

    pub_type: 杂志文章


    authors: Liu YT,Lin LW,Chen CY,Wang CP,Liu HP,Houng JY,Chung FM,Shieh TY

    更新日期:2012-12-01 00:00:00

  • Clinical features of post-radiation nasopharyngeal necrosis and their outcomes following surgical intervention in nasopharyngeal cancer patients.

    abstract:PURPOSE:To investigate the incidence and clinical features of post-radiation nasopharyngeal necrosis (PRNN), and effectiveness of surgical intervention for its treatment. MATERIALS AND METHODS:Retrospectively, we reviewed 380 NPC patients who underwent high dose radiotherapy (RT) (single RT in 355 and re-RT in 25) fro...

    journal_title:Oral oncology

    pub_type: 杂志文章


    authors: Yang K,Ahn YC,Nam H,Hong SD,Oh D,Noh JM

    更新日期:2021-01-23 00:00:00

  • Significant association of PD-L1 expression with human papillomavirus positivity and its prognostic impact in oropharyngeal cancer.

    abstract:BACKGROUND:The programmed death pathway plays a role in persistent human papillomavirus (HPV) infection as well as in resistance to immune elimination during malignant progression. In this study, we examined PD-L1 expression by immunohistochemistry and tumour infiltrating lymphocytes (TIL) in 214 patients with orophary...

    journal_title:Oral oncology

    pub_type: 杂志文章


    authors: Hong AM,Ferguson P,Dodds T,Jones D,Li M,Yang J,Scolyer RA

    更新日期:2019-05-01 00:00:00

  • Pre-treatment tumor-specific growth rate as a temporal biomarker that predicts treatment failure and improves risk stratification for oropharyngeal cancer.

    abstract:PURPOSE:To assess the relationship between tumor-specific growth rate (TSGR) and oropharyngeal cancer (OPC) outcomes in the HPV era. METHODS/MATERIALS:Primary tumor volume differences between a diagnostic and secondary scan separated ⩾7days without interval treatment were used to estimate TSGR, defined as percent volu...

    journal_title:Oral oncology

    pub_type: 杂志文章


    authors: Murphy CT,Devarajan K,Wang LS,Mehra R,Ridge JA,Fundakowski C,Galloway TJ

    更新日期:2015-11-01 00:00:00

  • Actinic cheilitis: epithelial expression of COX-2 and its association with mast cell tryptase and PAR-2.

    abstract::Cyclooxygenase-2 (COX-2) is overexpressed in various types of human malignancies, including oral cancers. Recent studies have shown that mast cell-derived protease tryptase can induce COX-2 expression by the cleavage of proteinase-activated receptor-2 (PAR-2). Actinic cheilitis (AC) is a premalignant form of lip cance...

    journal_title:Oral oncology

    pub_type: 杂志文章


    authors: Rojas IG,Martínez A,Brethauer U,Grez P,Yefi R,Luza S,Marchesani FJ

    更新日期:2009-03-01 00:00:00

  • Evaluation of a new binary system of grading oral epithelial dysplasia for prediction of malignant transformation.

    abstract::The aim of this paper is to assess the reproducibility of a novel binary grading system (high/low risk) of oral epithelial dysplasia and to compare it with the WHO classification 2005. The accuracy of the new system for predicting malignant transformation was also assessed. Ninety-six consecutive oral epithelial dyspl...

    journal_title:Oral oncology

    pub_type: 杂志文章


    authors: Kujan O,Oliver RJ,Khattab A,Roberts SA,Thakker N,Sloan P

    更新日期:2006-11-01 00:00:00

  • Comparison of different lymph node staging systems in patients with positive lymph nodes in oral squamous cell carcinoma.

    abstract:OBJECTIVES:The evaluation of neck lymph node metastasis is critical for predicting survival after head and neck cancer treatment. However, traditional pathological N staging does not completely correlate with survival; the total number of lymph nodes resected during surgery affects staging, and a minimal number of node...

    journal_title:Oral oncology

    pub_type: 杂志文章


    authors: Lin NC,Su IH,Hsu JT,Chang YJ,Tsai KY

    更新日期:2021-01-16 00:00:00

  • Exfoliative cytology of normal buccal mucosa to predict the relative risk of cancer in the upper aerodigestive tract using the MN-assay.

    abstract::The high frequency of second or third primary tumors was first explained by Slaughter et al. with the concept of field cancerisation. Another theory postulates micrometastatic lesions as a reason for this phenomenon. The micronuclei (MN)-assay was evaluated to provide evidence for the concept of field cancerisation an...

    journal_title:Oral oncology

    pub_type: 杂志文章


    authors: Bloching M,Hofmann A,Lautenschläger C,Berghaus A,Grummt T

    更新日期:2000-11-01 00:00:00

  • Determination of antibodies directed at EBV proteins expressed in both latent and lytic cycles in nasopharyngeal carcinoma.

    abstract:OBJECTIVES:Serologic analyses for anti-EBV antibodies used alone usually have low sensitivity for the diagnosis of nasopharyngeal carcinoma (NPC). We assumed that a combined determination of antibodies directed at EBV proteins expressed in both lytic and latent cycles could increase the sensitivity. MATERIALS AND METH...

    journal_title:Oral oncology

    pub_type: 杂志文章


    authors: Ai P,Wang T,Zhang H,Wang Y,Song C,Zhang L,Li Z,Hu H

    更新日期:2013-04-01 00:00:00

  • Midkine expression in malignant salivary gland tumors and its role in tumor angiogenesis.

    abstract::The aims of this study were to investigate midkine (MK) expression patterns in salivary gland tumors (SGTs) and to evaluate the correlation between MK expression and the degree of malignancy. We performed immunohistochemistry to examine MK expression in specimens of adenoid cystic carcinoma (ACC), mucoepidermoid carci...

    journal_title:Oral oncology

    pub_type: 杂志文章


    authors: Ota T,Ota K,Jono H,Fujimori H,Ueda M,Shinriki S,Sueyoshi T,Shinohara M,Ando Y

    更新日期:2010-09-01 00:00:00

  • Comparative study of sentinel lymph node biopsy in clinically N0 oral tongue squamous cell carcinoma: Long-term oncologic outcomes between validation and application phases.

    abstract:OBJECTIVE:This study tested the long-term outcomes of sentinel lymph node biopsy (SLNB) for oral tongue squamous cell carcinoma (SCC) during the transition from validation to application phase. MATERIALS AND METHODS:Sensitivity, negative predictive value (NPV), neck control rate, disease-specific survival (DSS), disea...

    journal_title:Oral oncology

    pub_type: 杂志文章


    authors: Chung MK,Lee GJ,Choi N,Cho JK,Jeong HS,Baek CH

    更新日期:2015-10-01 00:00:00

  • Eosinophil ablation and tumor development.

    abstract::Tissue eosinophilia in squamous cell carcinoma has long been recognized; however, the role of eosinophils in tumor development remains unclear. Studies have reported both favorable and unfavorable prognoses for patients with tumors exhibiting tumor-associated tissue eosinophilia (TATE). This study seeks to elucidate t...

    journal_title:Oral oncology

    pub_type: 杂志文章


    authors: Wong DT,Bowen SM,Elovic A,Gallagher GT,Weller PF

    更新日期:1999-09-01 00:00:00

  • Proliferative verrucous vs conventional leukoplakia: no significantly increased risk of HPV infection.

    abstract::Proliferative verrucous leukoplakia (PVL) is a very aggressive form of oral leukoplakia (OL) with high morbidity and mortality rates, hypothesised to be linked to HPV infection. This study aimed to determine the presence of HPV DNA in PVL in comparison with OL, and in relation to social-demographical variables (age, g...

    journal_title:Oral oncology

    pub_type: 杂志文章,多中心研究


    authors: Campisi G,Giovannelli L,Ammatuna P,Capra G,Colella G,Di Liberto C,Gandolfo S,Pentenero M,Carrozzo M,Serpico R,D'Angelo M

    更新日期:2004-09-01 00:00:00

  • Relationship between the expressions of PD-L1 and tumor-infiltrating lymphocytes in oral squamous cell carcinoma.

    abstract::Tumor-infiltrating lymphocytes (TILs) are considered to represent immune reactions of the host to a malignant tumor. Programmed death receptor ligand-1 (PD-L1) is a surface protein that blocks the function of T lymphocytes and is expressed on cancer cells. Tumor-associated fibroblasts (TAFs), which influence tumor gro...

    journal_title:Oral oncology

    pub_type: 杂志文章


    authors: Cho YA,Yoon HJ,Lee JI,Hong SP,Hong SD

    更新日期:2011-12-01 00:00:00

  • miR-24 up-regulation in oral carcinoma: positive association from clinical and in vitro analysis.

    abstract::MicroRNAs (miRNAs) play important roles in neoplastic process. miR-24 is localized on chromosome 9q22 and 19p13, regions frequently altered in oral squamous cell carcinoma (OSCC). This study showed that miR-24 was up-regulated in OSCC tissues relative to control samples. In addition, the plasma levels of miR-24 in OSC...

    journal_title:Oral oncology

    pub_type: 杂志文章


    authors: Lin SC,Liu CJ,Lin JA,Chiang WF,Hung PS,Chang KW

    更新日期:2010-03-01 00:00:00

  • Expression of keratins in normal, immortalized and malignant oral epithelia in organotypic culture.

    abstract::Keratins have been extensively studied in tissues and cultured keratinocytes but limited information is available on epithelia reconstructed in vitro. The aim of this study was to examine keratin expression in organotypic epithelia with normal (NOK), immortalized (SVpgC2a) and malignant (SqCC/Y1) human buccal cells. O...

    journal_title:Oral oncology

    pub_type: 杂志文章


    authors: Hansson A,Bloor BK,Haig Y,Morgan PR,Ekstrand J,Grafström RC

    更新日期:2001-07-01 00:00:00

  • Periodontal disease and periodontal management in patients with cancer.

    abstract::Periodontal infection may exacerbate during cancer therapy and may result in oral pain and infection, and systemic infection, which may cause morbidity and can lead to mortality in neutropenic cancer patients. Periodontal disease in head and neck cancer patients treated with radiation therapy may lead to acute and chr...

    journal_title:Oral oncology

    pub_type: 杂志文章,评审


    authors: Epstein JB,Stevenson-Moore P

    更新日期:2001-12-01 00:00:00

  • A comparison of mandible preservation method and mandibulotomy approach in oral and oropharyngeal cancer: A meta-analysis.

    abstract:OBJECTIVE:This study aims to compare the prognoses outcomes of mandibular preservation method (MPM) and the mandibulotomy approach (MLA) in oral and oropharyngeal cancer (OOPC) patients. METHOD:We searched PubMed, Web of Science, EMBASE, Chinese BioMedical Literature Database (CBM), Cochrane Library, and clinicaltrial...

    journal_title:Oral oncology

    pub_type: 杂志文章,meta分析


    authors: Pang P,Li RW,Shi JP,Xu ZF,Duan WY,Liu FY,Huang SH,Tan XX,Sun CF

    更新日期:2016-12-01 00:00:00

  • Survival impact and toxicity of metformin in head and neck cancer: An analysis of the SEER-Medicare dataset.

    abstract:OBJECTIVES:Recent preclinical research has renewed interest in the interplay between glucose dysregulation and cancer. Metformin holds promise as an adjunctive antineoplastic agent in head and neck cancer (HNC). We aimed to explore the impact of metformin in HNC patients from a population-based dataset. PATIENTS & MET...

    journal_title:Oral oncology

    pub_type: 杂志文章


    authors: Stokes WA,Eguchi M,Amini A,Hararah MK,Ding D,McDermott JD,Bradley CJ,Karam SD

    更新日期:2018-09-01 00:00:00

  • Molecular cloning, isolation and characterisation of ERK3 gene from chewing-tobacco induced oral squamous cell carcinoma.

    abstract::The mitogen activated serine/threonine kinases (MAPKs) constitute extracellular signal-regulated protein kinases (ERKs), c-Jun N-terminal kinases (JNKs) and p38 MAPK, with an important role in cell proliferation and transformation. Earlier studies from our laboratory had indicated a role for MAPK pathway in oral cance...

    journal_title:Oral oncology

    pub_type: 杂志文章


    authors: Rai R,Mahale A,Saranath D

    更新日期:2004-08-01 00:00:00