当前位置： SCI文献检索 > ORAL ONCOLOGY期刊下所有文献 > Tooth extraction in patients on zoledronic acid therapy.

Tooth extraction in patients on zoledronic acid therapy.

Abstract：

OBJECTIVES:Surgical management of patients following zoledronic acid therapy is particularly difficult, since the dental extraction is the main cause of BRONJ. METHODS:A case-control study was conducted on 176 patients treated with intravenous (IV) bisphosphonates for oncologic pathologies who also underwent dental extractions. The study was divided randomly into two groups: 91 were treated with Plasma Rich in Growth Factor Plasma (PRGF) (study group) and the other 85 were not treated with the growth factor preparation (control group). RESULTS:Panoramic X-ray and computed tomography were performed both before and 60 months after surgery. By clinical and radiological diagnosis, BRONJ was diagnosed in only 5 patients in the control group at an average of 91, 6 days after tooth extraction. CONCLUSIONS:We hypothesize that Plasma Rich in Growth Factor (PRGF) is important for the successful treatment of patients on bisphosphonates to restore the osteoblast/osteoclast homeostatic cycles via autologous cytokines. Moreover, this protocol reduces the risk of BRONJ when it is necessary to perform dental extractions in patients undergoing IV bisphosphonate treatment.

journal_name

Oral Oncol

journal_title

Oral oncology

authors

Mozzati M,Arata V,Gallesio G

doi

10.1016/j.oraloncology.2012.03.009

subject

Has Abstract

pub_date

2012-09-01 00:00:00

pages

817-21

issue

9

eissn

1368-8375

issn

1879-0593

pii

S1368-8375(12)00097-8

journal_volume

48

pub_type

杂志文章,随机对照试验

相关文献

ORAL ONCOLOGY文献大全
  • Altered-fractionation radiotherapy improves local control in early-stage glottic carcinoma: A systematic review and meta-analysis of 1762 patients.

    abstract：OBJECTIVES:To perform a systematic review of 1762 patients to comprehensively assess the benefit of altered-fractionation radiotherapy (ART) in early stage glottic carcinoma (ESGC). MATERIALS AND METHODS:Studies were identified in PubMed and EMBASE. Inclusion criteria were: (1) diagnosis of squamous cell ESGC (Tis, T1...

    journal_title：Oral oncology

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.oraloncology.2019.04.007

    authors： Sapienza LG,Ning MS,Taguchi S,Calsavara VF,Pellizzon ACA,Gomes MJL,Kowalski LP,Baiocchi G

    更新日期：2019-06-01 00:00:00

  • Interaction between the immune system and tongue squamous cell carcinoma induced by 4-nitroquinoline N-oxide in mice.

    abstract：:Squamous cell carcinoma of the oral cavity (SCC) accounts for 3% of cancers in the western world and 40% of cancers in India. The overall 5-year survival rate is only 50%. Most of the lesions appear intra-orally on the tongue. Results from a previous study demonstrated a significant increase in T and B-lymphocytes und...

    journal_title：Oral oncology

    pub_type： 杂志文章

    doi：10.1016/j.oraloncology.2003.08.008

    authors： Gannot G,Buchner A,Keisari Y

    更新日期：2004-03-01 00:00:00

  • Gene expression profiling reveals biological pathways responsible for phenotypic heterogeneity between UK and Sri Lankan oral squamous cell carcinomas.

    abstract：OBJECTIVES:It is well recognized that oral squamous cell carcinoma (OSCC) cases from Asia that are associated with betel quid chewing are phenotypically distinct to those from Western countries that are predominantly caused by smoking/drinking, but the molecular basis of these differences are largely unknown. The aim o...

    journal_title：Oral oncology

    pub_type： 杂志文章

    doi：10.1016/j.oraloncology.2014.12.004

    authors： Saeed AA,Sims AH,Prime SS,Paterson I,Murray PG,Lopes VR

    更新日期：2015-03-01 00:00:00

  • Salivary gland cancer stem cells.

    abstract：:Emerging evidence suggests the existence of a tumorigenic population of cancer cells that demonstrate stem cell-like properties such as self-renewal and multipotency. These cells, termed cancer stem cells (CSC), are able to both initiate and maintain tumor formation and progression. Studies have shown that CSC are res...

    journal_title：Oral oncology

    pub_type： 杂志文章,评审

    doi：10.1016/j.oraloncology.2013.05.013

    authors： Adams A,Warner K,Nör JE

    更新日期：2013-09-01 00:00:00

  • Safety of boneless reconstruction of the mandible with a CAD/CAM designed titanium device: The replica cohort study.

    abstract：OBJECTIVE:We evaluated the safety of REPLICA, a CAD/CAM-designed patient-specific titanium mandible, in patients with mandibular defects not suitable for reconstruction with traditional techniques. PATIENTS AND METHODS:We performed a cohort study with a composite primary outcome assigned at the end of a 1-year follow-...

    journal_title：Oral oncology

    pub_type： 杂志文章

    doi：10.1016/j.oraloncology.2020.105073

    authors： Bedogni A,Bettini G,Bedogni G,Menapace G,Sandi A,Michelon F,Di Carlo R,Franco P,Saia G

    更新日期：2021-01-01 00:00:00

  • Evaluation of bax and bcl-2 expression in odontogenic keratocysts and orthokeratinized odontogenic cysts: A comparison of two cysts.

    abstract：:Odontogenic keratocyst (OKC) has an aggressive clinical course and a high tendency toward recurrence, while orthokeratinized odontogenic cyst has different characteristics and does not show aggressive behavior. Bax and bcl-2 are two important anti-apoptotic and pro-apoptotic factors of the bcl-2 family. The different ...

    journal_title：Oral oncology

    pub_type： 杂志文章

    doi：10.1016/j.oraloncology.2008.12.007

    authors： Rangiani A,Motahhary P

    更新日期：2009-07-01 00:00:00

  • Expression of vascular endothelial growth factor-C predicts regional lymph node metastasis in early oral squamous cell carcinoma.

    abstract：:The purpose of this study was to investigate the association of the expression of vascular endothelial growth factor-C (VEGF-C) with regional lymph node metastasis in oral squamous cell carcinoma (OSCC). The expression of VEGF-C in biopsy specimens obtained from 62 patients with OSCC was examined by immunohistochemist...

    journal_title：Oral oncology

    pub_type： 杂志文章

    doi：10.1016/s1368-8375(02)00143-4

    authors： Kishimoto K,Sasaki A,Yoshihama Y,Mese H,Tsukamoto G,Matsumura T

    更新日期：2003-06-01 00:00:00

  • p53-Reactivating small molecules induce apoptosis and enhance chemotherapeutic cytotoxicity in head and neck squamous cell carcinoma.

    abstract：:We evaluate whether p53-reactivating (p53RA) small molecules induce p53-dependent apoptosis in head and neck squamous cell carcinoma (HNSCC), a question that has not been previously addressed in head and neck cancer. PRIMA-1, CP-31398, RITA, and nutlin-3 were tested in four human HNSCC cell lines differing in TP53 sta...

    journal_title：Oral oncology

    pub_type： 杂志文章

    doi：10.1016/j.oraloncology.2010.10.011

    authors： Roh JL,Kang SK,Minn I,Califano JA,Sidransky D,Koch WM

    更新日期：2011-01-01 00:00:00

  • Genomic DNA copy number alterations from precursor oral lesions to oral squamous cell carcinoma.

    abstract：:Oral cancer is a multifactorial disease in which both environmental and genetic factors contribute to the aetiopathogenesis. Oral cancer is the sixth most common cancer worldwide with a higher incidence among Melanesian and South Asian countries. More than 90% of oral cancers are oral squamous cell carcinoma (OSCC). T...

    journal_title：Oral oncology

    pub_type： 杂志文章,评审

    doi：10.1016/j.oraloncology.2014.02.005

    authors： Salahshourifar I,Vincent-Chong VK,Kallarakkal TG,Zain RB

    更新日期：2014-05-01 00:00:00

  • Glutathione S-transferase M1 or T1 null genotype as a risk factor for developing multiple primary neoplasms in the upper aero-digestive tract, in Indian males using tobacco.

    abstract：:In this study conducted amongst Indian male tobacco users with upper aero-digestive tract (UADT) squamous carcinoma, 30 patients with multiple primary neoplasms (MPN) were compared with 28 age and sex matched patients with a single primary neoplasm (SPN) for various environmental factors (form of tobacco use, alcohol,...

    journal_title：Oral oncology

    pub_type： 杂志文章

    doi：10.1016/s1368-8375(03)00140-4

    authors： Jhavar S,Sarin R,Mulherkar R,Benner A,Agarwal JP,Dinshaw K

    更新日期：2004-01-01 00:00:00

  • Low incidence of H-, K- and N-ras oncogene mutations in cytological specimens of laryngeal tumours.

    abstract：:Laryngeal cancer is a rare type of neoplasia, constituting approximately 2% of all human cancers. Mutations of the ras gene family is one of the main activating mechanisms in human cancer. Their involvement in head and neck cancer has been mainly demonstrated at the level of the overexpression whereas ras mutations in...

    journal_title：Oral oncology

    pub_type： 杂志文章

    doi：10.1016/s1368-8375(99)00032-9

    authors： Rizos E,Sourvinos G,Arvanitis DA,Velegrakis G,Spandidos DA

    更新日期：1999-11-01 00:00:00

  • Interventions for the management of radiotherapy-induced xerostomia and hyposalivation: A systematic review and meta-analysis.

    abstract：INTRODUCTION:Salivary gland hypofunction is a common and permanent adverse effect of radiotherapy to the head and neck. Randomised trials of available treatment modalities have produced unclear results and offer little reliable guidance for clinicians to inform evidence-based therapy. We have undertaken this systematic...

    journal_title：Oral oncology

    pub_type： 杂志文章,meta分析,评审

    doi：10.1016/j.oraloncology.2016.12.031

    authors： Mercadante V,Al Hamad A,Lodi G,Porter S,Fedele S

    更新日期：2017-03-01 00:00:00

  • Salvage gemcitabine-vinorelbine chemotherapy in patients with metastatic nasopharyngeal carcinoma pretreated with platinum-based chemotherapy.

    abstract：OBJECTIVES:Platinum-based chemotherapy is the recognized first-line treatment for metastatic nasopharyngeal carcinoma (NPC). However there is no standard second-line treatment. This study was designed to evaluate the efficacy and safety of a gemcitabine and vinorelbine combination (GV) in patients with metastatic NPC p...

    journal_title：Oral oncology

    pub_type： 杂志文章

    doi：10.1016/j.oraloncology.2012.05.021

    authors： Chen C,Wang FH,Wang ZQ,An X,Luo HY,Zhang L,Chen YC,Xu RH,Li YH

    更新日期：2012-11-01 00:00:00

  • Evaluation of the immunogenicity of ALDH(high) human head and neck squamous cell carcinoma cancer stem cells in vitro.

    abstract：OBJECTIVES:To establish the concept that the antigenicity/immunogenicity of ALDH(high) human head and neck squamous cell carcinoma (HNSCC) cancer stem cells (CSC) is distinct from that of ALDH(low) non-CSCs. METHODS:We generated CSC-loaded dendritic cells (DCs) to sensitize autologous peripheral blood T, B lymphocytes...

    journal_title：Oral oncology

    pub_type： 杂志文章

    doi：10.1016/j.oraloncology.2016.05.013

    authors： Prince MEP,Zhou L,Moyer JS,Tao H,Lu L,Owen J,Etigen M,Zheng F,Chang AE,Xia J,Wolf G,Wicha MS,Huang S,Ren X,Li Q

    更新日期：2016-08-01 00:00:00

  • Functional imaging early during (chemo)radiotherapy for response prediction in head and neck squamous cell carcinoma; a systematic review.

    abstract：:This systematic review gives an extensive overview of the current state of functional imaging during (chemo)radiotherapy to predict locoregional control (LRC) and overall survival (OS) for head and neck squamous cell carcinoma. MEDLINE and EMBASE were searched for literature until April 2018 assessing the predictive p...

    journal_title：Oral oncology

    pub_type： 杂志文章

    doi：10.1016/j.oraloncology.2018.11.005

    authors： Martens RM,Noij DP,Ali M,Koopman T,Marcus JT,Vergeer MR,de Vet H,de Jong MC,Leemans CR,Hoekstra OS,de Bree R,de Graaf P,Boellaard R,Castelijns JA

    更新日期：2019-01-01 00:00:00

  • Eosinophil ablation and tumor development.

    abstract：:Tissue eosinophilia in squamous cell carcinoma has long been recognized; however, the role of eosinophils in tumor development remains unclear. Studies have reported both favorable and unfavorable prognoses for patients with tumors exhibiting tumor-associated tissue eosinophilia (TATE). This study seeks to elucidate t...

    journal_title：Oral oncology

    pub_type： 杂志文章

    doi：10.1016/s1368-8375(99)00023-8

    authors： Wong DT,Bowen SM,Elovic A,Gallagher GT,Weller PF

    更新日期：1999-09-01 00:00:00

  • The landscape of gene fusions and somatic mutations in salivary gland neoplasms - Implications for diagnosis and therapy.

    abstract：:Recent studies of the genomic landscape of salivary gland tumors have provided important insights into the molecular pathogenesis of these tumors. The most consistent alterations identified include a translocation-generated gene fusion network involving transcription factors, transcriptional coactivators, tyrosine kin...

    journal_title：Oral oncology

    pub_type： 杂志文章,评审

    doi：10.1016/j.oraloncology.2016.04.002

    authors： Andersson MK,Stenman G

    更新日期：2016-06-01 00:00:00

  • Quality insurance in head and neck cancer multidisciplinary team meetings: A watchful eye on real-life experience.

    abstract：INTRODUCTION:Although Multidisciplinary Team Management (MDT) is integrated in most international head and neck cancer treatment guidelines, its applications and proceedings were rarely described. The present study explores a 6-year real-life experience in a French Comprehensive Cancer Care Center. METHODS:Patients, t...

    journal_title：Oral oncology

    pub_type： 杂志文章

    doi：10.1016/j.oraloncology.2019.02.020

    authors： Guy JB,Benna M,Xia Y,Daguenet E,Ben Mrad M,Jmour O,Vial N,Lelonge Y,Fournel P,Prades JM,Vallard A,Magné N

    更新日期：2019-04-01 00:00:00

  • A prospective randomized controlled trial on the value of prophylactic oral nutritional supplementation in locally advanced nasopharyngeal carcinoma patients receiving chemo-radiotherapy.

    abstract：OBJECTIVES:We investigated the effect of prophylactic oral nutrition supplements (ONS) in locally advanced nasopharyngeal carcinoma patients receiving neoadjuvant chemotherapy and concurrent chemoradiotherapy (CCRT). METHODS:Eligible patients were randomly assigned to an intervention or control group. Patients in the ...

    journal_title：Oral oncology

    pub_type： 杂志文章

    doi：10.1016/j.oraloncology.2020.105025

    authors： Huang S,Piao Y,Cao C,Chen J,Sheng W,Shu Z,Hua Y,Jiang F,Hu Q,Chen X,Chen Y

    更新日期：2020-12-01 00:00:00

  • Silencing Met receptor tyrosine kinase signaling decreased oral tumor growth and increased survival of nude mice.

    abstract：OBJECTIVES:The hepatocyte growth factor receptor (Met) is frequently overexpressed in Head and Neck Squamous Cell Carcinoma (HNSCC), correlating positively with high-grade tumors and shortened patient survival. As such, Met may represent an important therapeutic target. The purpose of this study was to explore the role...

    journal_title：Oral oncology

    pub_type： 杂志文章

    doi：10.1016/j.oraloncology.2013.10.014

    authors： Tao X,Hill KS,Gaziova I,Sastry SK,Qui S,Szaniszlo P,Fennewald S,Resto VA,Elferink LA

    更新日期：2014-02-01 00:00:00

  • Association between oral leukoplakia and upper gastrointestinal cancers: a 28-year follow-up study in the Linxian General Population Trial.

    abstract：BACKGROUND:Oral leukoplakia is a precancerous disorder that is common among residents in Linxian. However, the associations between oral leukoplakia and upper gastrointestinal cancers have not been reported. We investigated the relationships between oral leukoplakia and upper gastrointestinal cancers in the Linxian Gen...

    journal_title：Oral oncology

    pub_type： 杂志文章

    doi：10.1016/j.oraloncology.2014.07.009

    authors： Fan JH,Wang JB,Qu CX,Zhang YQ,Taylor PR,Abnet CC,Dawsey SM,Qiao YL

    更新日期：2014-10-01 00:00:00

  • Smoking and alcohol in the etiology of oral cancer: gender-specific risk profiles in the south of Greece.

    abstract：:Oral and pharyngeal cancer (OC) mortality is very low in Greece, especially among men, compared to other European countries. We conducted a case-control study of OC in Athens, and obtained information on tobacco, alcohol use and other potential risk factors and confounding variables for 110 incident cases and 115 hosp...

    journal_title：Oral oncology

    pub_type： 杂志文章

    doi：10.1016/s1368-8375(00)00060-9

    authors： Zavras AI,Douglass CW,Joshipura K,Wu T,Laskaris G,Petridou E,Dokianakis G,Segas J,Lefantzis D,Nomikos P,Wang YF,Diehl SR

    更新日期：2001-01-01 00:00:00

  • Molecular alterations in the tumor suppressor gene WWOX in oral leukoplakias.

    abstract：:Oral leukoplakia is the most prevalent and potentially malignant disorder of the oral mucosa. Previous studies have demonstrated that molecular changes of the WWOX gene (WW-domain containing oxidoreductase), a candidate tumor suppressor gene located at 16q23.3-24.1 that spans FRA16D, the second most common fragile sit...

    journal_title：Oral oncology

    pub_type： 杂志文章

    doi：10.1016/j.oraloncology.2007.08.019

    authors： Pimenta FJ,Cordeiro GT,Pimenta LG,Viana MB,Lopes J,Gomez MV,Aldaz CM,De Marco L,Gomez RS

    更新日期：2008-08-01 00:00:00

  • Treatment and outcomes of nasopharyngeal carcinoma in a unique non-endemic population.

    abstract：OBJECTIVE:Nasopharyngeal carcinoma (NPC) is common in Southeast Asia. Due to the influx of immigrants from this region, the incidence in British Columbia is increasing. Current literature from non-endemic populations encompasses heterogeneous cohorts. This study examines NPC in a North American population, with a high ...

    journal_title：Oral oncology

    pub_type： 杂志文章

    doi：10.1016/j.oraloncology.2021.105182

    authors： Howlett J,Hamilton S,Ye A,Jewett D,Riou-Green B,Prisman E,Thamboo A

    更新日期：2021-01-24 00:00:00

  • Analysis of amelogenin gene (AMGX, AMGY) expression in ameloblastoma.

    abstract：:Although the amelogenin gene is expressed in ameloblastoma, the precise expression pattern of X and Y amelogenin genes (AMGX, AMGY) in this tumor has not yet been identified. In this study, we analyzed amelogenin gene expression in 19 samples (9 male, 10 female) of oral ameloblastomas by RT-PCR and detect the chromoso...

    journal_title：Oral oncology

    pub_type： 杂志文章

    doi：10.1016/j.oraloncology.2005.04.005

    authors： Tsujigiwa H,Nagatsuka H,Han PP,Gunduz M,Siar CH,Oida S,Nagai N

    更新日期：2005-09-01 00:00:00

  • Management principles of head and neck cancers during pregnancy: a review and case series.

    abstract：:Head and neck cancers during pregnancy are rising in incidence. Clinicians need to be aware of the principles of managing these cases. This paper is a review of the literature of head and neck cancers during pregnancy with a short case series of six non-thyroid pregnancy-associated cancers treated by a head and neck o...

    journal_title：Oral oncology

    pub_type： 杂志文章,评审

    doi：10.1016/j.oraloncology.2007.02.003

    authors： Atabo A,Bradley PJ

    更新日期：2008-03-01 00:00:00

  • Pioglitazone and oral cancer risk in patients with type 2 diabetes.

    abstract：BACKGROUND:Pioglitazone has shown an inhibitory effect on the growth of cell lines derived from human salivary gland and human oral squamous cell carcinoma. However, whether this effect can be applied to patients with type 2 diabetes mellitus who use pioglitazone for glycemic control remains unanswered. METHODS:The re...

    journal_title：Oral oncology

    pub_type： 杂志文章

    doi：10.1016/j.oraloncology.2013.10.015

    authors： Tseng CH

    更新日期：2014-02-01 00:00:00

  • Bilateral mucoepidermoid carcinomas arising in bilateral pre-existing Warthin's tumours of the parotid gland.

    abstract：:A unique case of bilateral mucoepidermoid carcinoma arising in pre-existing bilateral Warthin's tumours of the parotid glands is presented. Reports of carcinomas arising in pre-existing unilateral Warthin's tumours are likewise rare with only 3 cases of concern mucoepidermoid carcinoma. This is the first report of bil...

    journal_title：Oral oncology

    pub_type： 杂志文章

    doi：10.1016/s0964-1955(97)00018-3

    authors： Seifert G

    更新日期：1997-07-01 00:00:00

  • Epithelial expression of p53, mdm-2 and p21 in normal lip and actinic cheilitis.

    abstract：:The p53 pathway is commonly altered during oral and skin carcinogenesis. The lip is a transition tissue between skin and oral mucosa, which in response to UVB exposure also exhibits alterations in the expression of p53 and p53-related genes that could lead to malignant transformation. To assess if the p53-regulated pr...

    journal_title：Oral oncology

    pub_type： 杂志文章

    doi：10.1016/j.oraloncology.2007.11.008

    authors： Martínez A,Brethauer U,Borlando J,Spencer ML,Rojas IG

    更新日期：2008-09-01 00:00:00

  • A gene expression profile associated with perineural invasion identifies a subset of HNSCC at risk of post-surgical recurrence.

    abstract：OBJECTIVES:Perineural invasion (PNI) is a common histopathological finding in head and neck squamous cell carcinoma (HNSCC). We aimed to explore the molecular mechanisms involved in PNI and the role of PNI as an aggressive pathological feature. MATERIALS AND METHODS:We used data from The Cancer Genome Atlas (TCGA) to ...

    journal_title：Oral oncology

    pub_type： 杂志文章

    doi：10.1016/j.oraloncology.2018.09.005

    authors： Saidak Z,Clatot F,Chatelain D,Galmiche A

    更新日期：2018-11-01 00:00:00