The effects of serotonin biosynthesis inhibition on nicotine and nifedipine-induced analgesia in rats.

abstract：UNLABELLED:Pain on injection of propofol continues to be a problem for anesthesiologists. A lipid-free formulation of propofol and a propofol emulsion containing medium-chain triglyceride have become available in the Indian market. We performed this study to assess the pain on injection of propofol emulsion containing ...

journal_title：Anesthesia and analgesia

authors： Dubey PK,Kumar A

更新日期：2005-10-01 00:00:00

abstract：:The ability of opiates to be a complete anesthetic has been assessed in animals. These studies have investigated the serum levels of opiate required to produce a decrease in anesthetic requirement for a concomitantly administered inhalation anesthetic. A linear dose-response relation has been observed between opiate s...

journal_title：Anesthesia and analgesia

authors： Stone DJ,DiFazio CA

更新日期：1988-07-01 00:00:00

abstract：:Nicardipine is used in the treatment of premature labor. There are no previous reports in the anesthesia literature of serious side effects associated with this drug. We report a case of pulmonary edema induced by nicardipine therapy for tocolysis in a pregnant 27-yr-old patient admitted to our hospital for preterm la...

journal_title：Anesthesia and analgesia

authors： Bal L,Thierry S,Brocas E,Adam M,Van de Louw A,Tenaillon A

更新日期：2004-09-01 00:00:00

abstract：:Transesophageal echocardiography (TEE) is increasingly used intraoperatively as a monitor of ventricular function and volume. Despite its increasing use, whether data from TEE monitoring can be interpreted accurately on-line in real-time is unknown. We studied the performance of five community-based, full-time cardiac...

journal_title：Anesthesia and analgesia

authors： Bergquist BD,Leung JM,Bellows WH

更新日期：1996-06-01 00:00:00

abstract：:Forty neonates delivered by cesarean section were studied, half being delivered of mothers in whom anesthesia was induced with midazolam (0.3 mg/kg intravenously) and half of mothers given thiopental (4 mg/kg). At delivery, blood samples from mother and the umbilical vein were drawn for determination of plasma concent...

journal_title：Anesthesia and analgesia

authors： Bach V,Carl P,Ravlo O,Crawford ME,Jensen AG,Mikkelsen BO,Crevoisier C,Heizmann P,Fattinger K

更新日期：1989-03-01 00:00:00

abstract：IMPLICATIONS:We report the successful use of the laryngeal mask airway for percutaneous endoscopic gastrostomy in an adult patient with a known difficult airway and severe cerebral palsy. ...

journal_title：Anesthesia and analgesia

authors： Brimacombe J,Newell S,Bergin A,McCarthy J,Barry J

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Propofol-evoked injection site pain is not observed with fospropofol. We hypothesized that unlike propofol, fospropofol does not activate the irritant receptor, transient receptor potential 1 (TRPA1). METHODS:We tested the hypothesis using electrophysiology and behavioral studies. RESULTS:Our data demonstr...

journal_title：Anesthesia and analgesia

authors： Patwardhan A,Edelmayer R,Annabi E,Price T,Malan P,Dussor G

更新日期：2012-10-01 00:00:00

abstract：:Although convective warming therapy is effective in preventing hypothermia in anesthetized patients, little is known concerning the potential risks of its use. Hence, this balanced cross-over study was designed to determine if the use of convective warming therapy increased the risk of wound contamination. For 4 h, ei...

journal_title：Anesthesia and analgesia

authors： Zink RS,Iaizzo PA

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Vital sign monitors and ventilator/anesthesia workstations are equipped with multiple alarms to improve patient safety. A high number of false alarms can lead to a "crying wolf" phenomenon with consecutively ignored critical situations. Systematic data on alarm patterns and density in the perioperative phase...

journal_title：Anesthesia and analgesia

authors： Schmid F,Goepfert MS,Kuhnt D,Eichhorn V,Diedrichs S,Reichenspurner H,Goetz AE,Reuter DA

更新日期：2011-01-01 00:00:00

abstract：:The effects of anesthetics on intracranial pressure (ICP) may be different in preterm neonates than in adults because the neonate's cranial sutures are not yet fused. The authors monitored changes in anterior fontanel pressure (AFP), a noninvasive indicator of ICP, during anesthesia in 44 preterm neonates without neur...

journal_title：Anesthesia and analgesia

authors： Friesen RH,Thieme RE,Honda AT,Morrison JE Jr

更新日期：1987-05-01 00:00:00

abstract：UNLABELLED:IV volume is often administered to patients in an intensive care unit (ICU) to improve cardiovascular function. We investigated the relationship between stroke volume (SV) and left ventricular (LV) size by using transesophageal echocardiography (TEE) in a population of 20 ICU patients and 21 postoperative ca...

journal_title：Anesthesia and analgesia

authors： Tousignant CP,Walsh F,Mazer CD

更新日期：2000-02-01 00:00:00

abstract：:Propofol is associated with a low incidence of postoperative nausea and vomiting. In a prospective, randomized, double-blind, placebo-controlled study, we investigated the possible direct antiemetic properties of a subhypnotic dose of propofol. Fifty-two ASA physical status I or II patients, aged 15-60 yr with nausea ...

journal_title：Anesthesia and analgesia

authors： Borgeat A,Wilder-Smith OH,Saiah M,Rifat K

更新日期：1992-04-01 00:00:00

abstract：:The pharmacokinetics of lidocaine were studied in nonpregnant and pregnant ewes. The maternal femoral vessels were cannulated and, on the day of study, the urinary bladder was catheterized. Lidocaine HCl, 4-5 mg/kg, was administered by IV injection over 60 seconds. Serial samples of arterial blood and urine were colle...

journal_title：Anesthesia and analgesia

authors： Santos AC,Pedersen H,Morishima HO,Finster M,Arthur GR,Covino BG

更新日期：1988-12-01 00:00:00

abstract：:In pregnant patients with myasthenia gravis and respiratory compromise, neuraxial anesthesia for lower abdominal surgery can risk further respiratory depression. We report the use of epidural anesthesia for dilation and curettage and tubal ligation in a 26-yr-old woman with a 12-wk intrauterine pregnancy with severe m...

journal_title：Anesthesia and analgesia

authors： Warren J,Sharma SK

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:The perioperative course of patients undergoing intracranial surgery is frequently complicated by hypertensive episodes. Dexmedetomidine (DEX), an alpha-2 adrenoreceptor agonist, is gaining popularity in neuroanesthesia, because its sympatholytic and antinociceptive properties may improve hemodynamic stabili...

journal_title：Anesthesia and analgesia

authors： Bekker A,Sturaitis M,Bloom M,Moric M,Golfinos J,Parker E,Babu R,Pitti A

更新日期：2008-10-01 00:00:00

abstract：:The low solubility of desflurane contributes to rapid emergence after outpatient anesthesia. Compared with isoflurane, recovery times to eye opening, response to verbal commands, and orientation to person, place, and time have been significantly shorter. Even when compared with the rapid, short-acting intravenous anes...

journal_title：Anesthesia and analgesia

authors： White PF

更新日期：1992-10-01 00:00:00

abstract：UNLABELLED:With the development of new computer-assisted target-controlled infusion (TCI) systems and the availability of short-acting anesthetics, total IV anesthesia (TIVA) has become increasingly popular. The aim of this study was to compare costs of TCI-based anesthesia with two standard anesthesia regimens. Sixty ...

journal_title：Anesthesia and analgesia

authors： Suttner S,Boldt J,Schmidt C,Piper S,Kumle B

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Hyperkalemia poses serious hazards to patients undergoing orthotopic liver transplantation (OLT), and its predictors have not been thoroughly examined. METHODS:We retrospectively studied 1124 consecutive adult patients who underwent OLT. Hyperkalemia was defined as serum K+ > or =5.5 mmol/L. A total of 47 r...

journal_title：Anesthesia and analgesia

authors： Xia VW,Ghobrial RM,Du B,Chen T,Hu KQ,Hiatt JR,Busuttil RW,Steadman RH

更新日期：2007-09-01 00:00:00

abstract：:Local anesthetics have been used clinically for more than a century, but new insights into their mechanisms of action and their interaction with biological systems continue to surprise researchers and clinicians alike. Next to their classic action on voltage-gated sodium channels, local anesthetics interact with calci...

journal_title：Anesthesia and analgesia

authors： Lirk P,Hollmann MW,Strichartz G

更新日期：2018-04-01 00:00:00

abstract：:Cimetidine blunts the increase in cerebral blood flow (CBF) normally observed during hypoxia. It is important, therefore, to know whether other H2-blockers also affect the cerebral circulation adaptation to hypoxia. Cerebral blood flow was measured in 24 awake dogs after an intravenous injection of either saline (cont...

journal_title：Anesthesia and analgesia

authors： Audibert G,Saunier C,Hartemann D,Bigard O,Haberer JP

更新日期：1991-04-01 00:00:00

abstract：UNLABELLED:We tested the hypothesis that routine cleaning and autoclaving does not remove protein deposits from reusable laryngeal mask airways (LMAs). All previously used classic and flexible LMAs from a single hospital were tested. Each LMA was hand-washed in an enzymatic solution for 3 min, machine-washed with a dis...

journal_title：Anesthesia and analgesia

authors： Clery G,Brimacombe J,Stone T,Keller C,Curtis S

更新日期：2003-10-01 00:00:00

abstract：:Sufentanil is a potent opioid that occasionally has been associated with hypotension. The mechanism behind this hypotension is unclear. We hypothesized that sufentanil had a direct effect on vascular smooth muscle to cause vasodilation. Sufentanil was infused into the brachial artery of 10 young, healthy volunteers at...

journal_title：Anesthesia and analgesia

authors： Ebert TJ,Ficke DJ,Arain SR,Holtz MN,Shankar H

更新日期：2005-12-01 00:00:00

abstract：:We were interested in determining the effect of enflurane, halothane, and isoflurane on the uptake and removal of 5-hydroxytryptamine (5-HT) and phenylethylamine (PEA) from the lung. Isolated rabbit lungs were perfused in a recirculating system in vitro with 0.1 microM [14C]5-HT or 0.1 microM [14C]PEA in Krebs-Ringer ...

journal_title：Anesthesia and analgesia

authors： Cook DR,Brandom BW

更新日期：1982-08-01 00:00:00

abstract：:A quest for a systems-level neuroscientific basis of anesthetic-induced loss and return of consciousness has been in the forefront of research for the past 2 decades. Recent advances toward the discovery of underlying mechanisms have been achieved using experimental electrophysiology, multichannel electroencephalograp...

journal_title：Anesthesia and analgesia

authors： Hudetz AG,Mashour GA

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Among the various factors influencing the success rate, onset time, and duration of peripheral nerve blocks, the role of local anesthetics concentration remains uncertain. In this prospective, randomized, single-blinded study, we evaluated whether varying the dilution of a fixed dose of mepivacaine solution ...

journal_title：Anesthesia and analgesia

authors： Cappelleri G,Ambrosoli AL,Turconi S,Gemma M,Ricci EB,Cornaggia G

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Near-infrared spectroscopy is used during cardiac surgery to monitor the adequacy of cerebral perfusion. In this systematic review, we evaluated available data for adult patients to determine (1) whether decrements in cerebral oximetry during cardiac surgery are associated with stroke, postoperative cognitiv...

journal_title：Anesthesia and analgesia

authors： Zheng F,Sheinberg R,Yee MS,Ono M,Zheng Y,Hogue CW

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Peripheral neuropathy is a common dose-limiting side effect of chemotherapy. There are no clinically proven analgesics for the treatment of this condition. Drugs from different classes have been tested with mixed results. Identification of novel molecular targets for analgesic(s) is important. Antagonism of ...

journal_title：Anesthesia and analgesia

authors： Wala EP,Crooks PA,McIntosh JM,Holtman JR Jr

更新日期：2012-09-01 00:00:00

abstract：UNLABELLED:Thiopental is a racemate. In this study, we examined whether thiopental total body clearance and its distribution into central nervous system (CNS) tissue of rats was enantioselective. Rats, either anesthetized with halothane or conscious and restrained, were infused to stepwise steady-state targets of 5, 10...

journal_title：Anesthesia and analgesia

authors： Mather LE,Edwards SR,Duke CC,Cousins MJ

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:Various different interventions can be used to reduce surgical blood loss; however, there is no "gold standard" for accurately measuring the volume of perioperative blood loss, and this makes it difficult to assess the efficacy of these interventions. METHODS:We used data from a previous multicenter double-...

journal_title：Anesthesia and analgesia

authors： Lopez-Picado A,Albinarrate A,Barrachina B

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Sugammadex is the first selective relaxant binding agent that has been studied for reversal of neuromuscular blockade induced by rocuronium and other steroidal non-depolarizing neuromuscular blocking agents (NMBAs). OBJECTIVES:To assess the efficacy and safety of sugammadex in reversing neuromuscular blocka...

journal_title：Anesthesia and analgesia

authors： Abrishami A,Ho J,Wong J,Yin L,Chung F

更新日期：2010-04-01 00:00:00