The Science of Local Anesthesia: Basic Research, Clinical Application, and Future Directions.

abstract：:A method involving sodium fusion and analysis by fluoride electrode, which has been used for the determination of total fluorinated metabolites of fluorine-containing drugs in physiologic fluids, is shown to be inapplicable to volatile fluorinated metabolites of volatile fluorinated anesthetic agents. The yields of in...

journal_title：Anesthesia and analgesia

authors： Ivanetich KM,Bradshaw JJ,Brittain T

更新日期：1982-09-01 00:00:00

abstract：UNLABELLED:A new infraclavicular brachial plexus block method has the patient supine with an adducted arm. The target is any of the three cords behind the pectoralis minor muscle. The point of needle insertion is the intersection between the clavicle and the coracoid process. The needle is advanced 0 degrees -30 degree...

journal_title：Anesthesia and analgesia

authors： Klaastad Ø,Smith HJ,Smedby O,Winther-Larssen EH,Brodal P,Breivik H,Fosse ET

更新日期：2004-01-01 00:00:00

abstract：:This study examined anesthetic development and hemodynamic changes during two techniques of hyperbaric lidocaine administration through 27-gauge intrathecal catheters for continuous spinal anesthesia in 55 elderly patients undergoing transurethral prostatic resection. Twenty-five patients were randomly assigned to rec...

journal_title：Anesthesia and analgesia

authors： Chan VW,Chung F,Gomez M,Seyone C,Baylon G

更新日期：1994-07-01 00:00:00

abstract：UNLABELLED:We compared the laryngeal mask airway ProSeal (PLMA) and the laryngeal tube airway (LTA), two new extraglottic airway devices, with respect to: 1) insertion success rates and times, 2) efficacy of seal, 3) ventilatory variables during pressure-controlled ventilation, 4) tidal volume in different head/neck po...

journal_title：Anesthesia and analgesia

authors： Brimacombe J,Keller C,Brimacombe L

更新日期：2002-09-01 00:00:00

abstract：:The anesthetic propofol (2,6 diisopropylphenol) mediates some of its effects by activating inhibitory chloride currents in the lower brainstem and spinal cord. The effects comprise direct activation of gamma-aminobutyric acid-A and glycine receptors in the absence of the natural agonist, as well as potentiation of the...

journal_title：Anesthesia and analgesia

authors： Ahrens J,Haeseler G,Leuwer M,Mohammadi B,Krampfl K,Dengler R,Bufler J

更新日期：2004-07-01 00:00:00

abstract：:Transesophageal echocardiography (TEE) is increasingly used intraoperatively as a monitor of ventricular function and volume. Despite its increasing use, whether data from TEE monitoring can be interpreted accurately on-line in real-time is unknown. We studied the performance of five community-based, full-time cardiac...

journal_title：Anesthesia and analgesia

authors： Bergquist BD,Leung JM,Bellows WH

更新日期：1996-06-01 00:00:00

abstract：:In a laboratory experiment, the expected analgesic action of 33% nitrous oxide was reversed by creating the expectancy of heightened awareness of bodily sensations. Pain threshold and tolerance of electrical tooth-pulp stimulation were significantly reduced. Results from a control study gave us a basis for comparison ...

journal_title：Anesthesia and analgesia

authors： Dworkin SF,Chen AC,LeResche L,Clark DW

更新日期：1983-12-01 00:00:00

abstract：:Total knee arthroplasty (TKA) may result in severe pain, and single-injection femoral nerve blocks (SFNB) have been demonstrated to have a limited duration of analgesia. Continuous femoral nerve blocks (CFNB) can prolong the analgesic duration of SFNB. We prospectively randomized 36 patients undergoing TKA to CFNB ver...

journal_title：Anesthesia and analgesia

authors： Salinas FV,Liu SS,Mulroy MF

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:We tested the hypothesis that inhibition of cyclooxygenase (COX) attenuates in vivo ventilator-induced lung injury (VILI) in a prospective, randomized laboratory investigation in a university-affiliated laboratory. Adult male rats were anesthetized and randomized with or without nonselective COX inhibition (...

journal_title：Anesthesia and analgesia

authors： Niitsu T,Tsuchida S,Peltekova V,Engelberts D,Copland I,Otulakowski G,Post M,Kavanagh BP

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Nerve-stimulated fade in muscle is generally accepted as a prejunctional phenomenon mediated by block of prejunctional acetylcholine receptors (AChRs) at the nerve terminal, whereas decrease of twitch tension is considered a postjunctional effect due to block of muscle AChRs. Using ligands with specific pre-...

journal_title：Anesthesia and analgesia

authors： Nagashima M,Yasuhara S,Martyn JA

更新日期：2013-05-01 00:00:00

abstract：UNLABELLED:Apparently large plasma volumes derived by indocyanine green (PV-ICG) have been determined in the initial period after induction of anesthesia. We tested the hypothesis that possible overestimation of PV-ICG occurs shortly after anesthetic induction. Anesthesia was induced in 13 patients with fentanyl bolus ...

journal_title：Anesthesia and analgesia

authors： Mi WD,Ishihara H,Sakai T,Matsuki A

更新日期：2003-11-01 00:00:00

abstract：:We studied the performance of a target-controlled drug infusion device, computer-assisted continuous infusion (CACI). Forty-one volunteers received one of midazolam (n = 11), propofol (n = 10), thiopental (n = 10), or fentanyl (n = 10) in sedative concentrations. Concentrations were kept constant for 45-70 min at five...

journal_title：Anesthesia and analgesia

authors： Veselis RA,Glass P,Dnistrian A,Reinsel R

更新日期：1997-05-01 00:00:00

abstract：:In the 1930s and 1940s, photo cells permitted German, English, and American physiologists to construct ear oximeters with red and infrared light, requiring calibration. In 1940 Squire recognized that changes of red and infrared light transmission caused by pneumatic tissue compression permitted saturation to be comput...

journal_title：Anesthesia and analgesia

authors： Severinghaus JW

更新日期：2007-12-01 00:00:00

abstract：:Ketanserin, a serotonin antagonist, was used to control blood pressure during cardiopulmonary bypass in 12 patients having cardiac surgery. The drug was administered as a 10 mg bolus followed by a continuous infusion of either 40, 80, or 120 mg/hr to maintain mean arterial blood pressure below 70 mm Hg. There were 16 ...

journal_title：Anesthesia and analgesia

authors： Lichtenthal PR,Wade LD,Rossi EC

更新日期：1987-11-01 00:00:00

abstract：:The tandem pore domain K channel family mediates background K currents present in excitable cells. Currents passed by certain members of the family are enhanced by volatile anesthetics, thus suggesting a novel mechanism of anesthesia. The newest member of the family, termed TRESK (TWIK [tandem pore domain weak inward ...

journal_title：Anesthesia and analgesia

authors： Liu C,Au JD,Zou HL,Cotten JF,Yost CS

更新日期：2004-12-01 00:00:00

abstract：:Electroconvulsive therapy (ECT) is a highly effective treatment for severe depression. However, its use is associated with significant posttreatment cognitive impairment. Magnetic seizure therapy (MST) was developed as an alternative therapy that could reduce postseizure side effects through the induction of more "foc...

journal_title：Anesthesia and analgesia

authors： White PF,Amos Q,Zhang Y,Stool L,Husain MM,Thornton L,Downing M,McClintock S,Lisanby SH

更新日期：2006-07-01 00:00:00

abstract：:We investigated the usefulness of peripheral flow index (PFI) measurement using a standard pulse oximetry digit probe for early prediction of successful regional blocks. Sixty-six patients scheduled for limb surgery underwent either axillary or sciatic block using a nerve stimulator technique with mepivacaine 1.5%. PF...

journal_title：Anesthesia and analgesia

authors： Galvin EM,Niehof S,Verbrugge SJ,Maissan I,Jahn A,Klein J,van Bommel J

更新日期：2006-07-01 00:00:00

abstract：IMPLICATIONS:Manipulating the density of local anesthetic solutions by using a simple formula may be clinically useful in producing optimal density solutions for spinal anesthesia under a variety of clinical conditions. ...

journal_title：Anesthesia and analgesia

authors： Hallworth SP,Fernando R,Stocks GM

更新日期：2002-06-01 00:00:00

abstract：UNLABELLED:We tested the hypothesis that electro-acupuncture at the Zusanli, Yanglingquan, and Kunlun acupuncture points on the legs decreases anesthetic requirement. Fourteen young, healthy volunteers were anesthetized with desflurane on two separate days. Needle electrodes were positioned at the three acupuncture poi...

journal_title：Anesthesia and analgesia

authors： Morioka N,Akça O,Doufas AG,Chernyak G,Sessler DI

更新日期：2002-07-01 00:00:00

abstract：:The hypnotic effects of propofol, midazolam, alfentanil, and their binary and triple combinations, were studied in 130 unpremedicated patients in a randomized, double-blind fashion. The ability to open eyes on verbal command was used as an end-point. Dose-response curves for the three drugs given separately and in com...

journal_title：Anesthesia and analgesia

authors： Vinik HR,Bradley EL Jr,Kissin I

更新日期：1994-02-01 00:00:00

abstract：:The hemodynamic effects of mivacurium chloride were studied in 54 adult cardiac patients anesthetized with midazolam and sufentanil. After baseline data were collected, a placebo (N = 9) or mivacurium was administered over 60 seconds, the latter in doses of 0.15 (N = 18), 0.20 (N = 18), or 0.25 (N = 9) mg/kg. Measurem...

journal_title：Anesthesia and analgesia

authors： Stoops CM,Curtis CA,Kovach DA,McCammon RL,Stoelting RK,Warren TM,Miller D,Bopp SK,Jugovic DJ,Abou-Donia MM

更新日期：1989-03-01 00:00:00

abstract：:Patients receiving metoprolol before cardiac revascularization surgery were randomly divided into those in whom metoprolol was discontinued before the operation (N = 10) and those in whom metoprolol was continued up to the time of operation (N = 10). Cardiovascular responses to neuroleptanesthesia and sternotomy were ...

journal_title：Anesthesia and analgesia

authors： Pontén J,Häggendal J,Milocco I,Waldenström A

更新日期：1983-04-01 00:00:00

abstract：:Patients undergoing potentially painful interventional radiological procedures generally require a combination of analgesia and sedation. This sedation/analgesia should allow the patient to communicate while also remaining calm. Bispectral index (BIS) monitoring could be useful in achieving this. The primary end-point...

journal_title：Anesthesia and analgesia

authors： Dahaba AA,Lischnig U,Kronthaler R,Bornemann H,Georgiev V,Rehak PH,Metzler H

更新日期：2006-08-01 00:00:00

abstract：UNLABELLED:To determine whether the "second gas effect" is valid, we determined the pharmacokinetics of 0.2% enflurane with or without 80% N2) (n = 7 each) under controlled constant volume ventilation in 14 young healthy male patients before their operations. The alveolar (end-tidal) concentration (FA) and inspired con...

journal_title：Anesthesia and analgesia

authors： Sun X-G,Su F,Shi YQ,Lee C

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Although invasive monitoring is the standard method for intracranial pressure (ICP) measurement, it is not without potential for serious complications. Noninvasive methods have been proposed as alternatives to invasive ICP monitoring. The study aimed to investigate the diagnostic accuracy of the currently av...

journal_title：Anesthesia and analgesia

authors： Sallam A,Abdelaal Ahmed Mahmoud M Alkhatip A,Kamel MG,Hamza MK,Yassin HM,Hosny H,Younis MI,Ramadan E,Algameel HZ,Abdelhaq M,Abdelkader M,Mills KE,Mohamed H

更新日期：2020-09-24 00:00:00

abstract：UNLABELLED:We performed this study to assess the influence of endotracheal tube (ETT) tip design (Murphy-tip versus Magill-tip) on nasal trauma during nasotracheal intubation with a conventional polyvinyl chloride ETT. Patients were randomly allocated to one of four groups (n = 25 each): Magill-tipped ETT and Murphy-ti...

journal_title：Anesthesia and analgesia

authors： Lee JH,Kim CH,Bahk JH,Park KS

更新日期：2005-10-01 00:00:00

abstract：UNLABELLED:C-fos and Fos expression, frequently used as a neural nociceptive marker, is altered by many drugs. The effects of histamine receptor antagonists on c-fos messenger (m)RNA expression are unknown. We examined the effect of local and systemic administration of pyrilamine (H(1) receptor antagonist) and cimetidi...

journal_title：Anesthesia and analgesia

authors： Ashmawi HA,Chambergo FS,Araújo Palmeira CC,de Paula Posso I

更新日期：2003-08-01 00:00:00

abstract：:Thirty patients undergoing craniotomies were given infusions of fentanyl 1 microgram X kg-1 X hr-1, sufentanil 0.1 microgram X kg-1 X hr-1, or normal saline in a double-blind study of cerebral relaxation. Significantly better relaxation scores were achieved in patients given a narcotic infusion, but there was no diffe...

journal_title：Anesthesia and analgesia

authors： Bristow A,Shalev D,Rice B,Lipton JM,Giesecke AH Jr

更新日期：1987-05-01 00:00:00

abstract：:The purpose of this study was to determine whether preoperative screening of pediatric patients, accomplished by means of a preoperative telephone call to their parents, would decrease the rate of cancellation or postponement of ambulatory surgical procedures. Data from 5031 patients scheduled for ambulatory surgery w...

journal_title：Anesthesia and analgesia

authors： Patel RI,Hannallah RS

更新日期：1992-08-01 00:00:00

abstract：UNLABELLED:We present the case of a 57-yr-old patient who suffered an unexplained cerebrovascular event 3 days after being struck by a motor vehicle. Workup demonstrated a previously unknown patient foramen ovale. The etiologies of paradoxical embolism in trauma are discussed. IMPLICATIONS:Paradoxical embolism after m...

journal_title：Anesthesia and analgesia

authors： Price MD,Kanake P,Talmor D

更新日期：2004-04-01 00:00:00