The "second gas effect" is not a valid concept.

abstract：:We tested the hypothesis that middle ear pressure (MEP) is influenced by the choice of airway device during anesthesia with or without nitrous oxide (N2O) in the gas mixture. Eighty consecutive anesthetized, paralyzed ventilated patients (ASA physical status I-II, 18-65 yr) were randomly allocated for airway managemen...

journal_title：Anesthesia and analgesia

authors： Hohlrieder M,Keller C,Brimacombe J,Eschertzhuber S,Luckner G,Abraham I,von Goedecke A

更新日期：2006-01-01 00:00:00

abstract：UNLABELLED:Hemorrhagic hypotension may aggravate the detrimental effects of head trauma on neurologic outcome. Our study examined whether using phenylephrine or large volumes of saline IV to increase mean arterial blood pressure (MAP) to 70, 80, or 90 mm Hg during the combination of head trauma and uncontrolled hemorrh...

journal_title：Anesthesia and analgesia

authors： Talmor D,Merkind V,Artru AA,Shapiro O,Geva D,Roytblat L,Shapira Y

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:Chronic pain is one of the most common complaints in patients with human immunodeficiency virus (HIV)-associated sensory neuropathy. Ryanodine receptor (RyR) and mitochondrial oxidative stress are involved in neuropathic pain induced by nerve injury. Here, we investigated the role of RyR and mitochondrial su...

journal_title：Anesthesia and analgesia

authors： Godai K,Takahashi K,Kashiwagi Y,Liu CH,Yi H,Liu S,Dong C,Lubarsky DA,Hao S

更新日期：2019-07-01 00:00:00

abstract：:Both epidural and general anesthetics alter autonomic balance. However, the relative differences between epidural (EA) and general anesthetics (GA) with regard to cardiac and peripheral sympathovagal balance have not been described. Twenty consecutive patients scheduled for radical retropubic prostatectomy were random...

journal_title：Anesthesia and analgesia

authors： Fleisher LA,Frank SM,Shir Y,Estafanous M,Kelly S,Raja SN

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:Patients of ASA physical status 1, 2, and 3 undergoing elective surgery do not have underlying conditions that are a constant threat to life, and hence should not be expected to be at significant risk for death on the day of surgery. METHODS:We analyzed 815,077 ASA physical status 1, 2, and 3 elective surge...

journal_title：Anesthesia and analgesia

authors： Bishop MJ,Souders JE,Peterson CM,Henderson WG,Domino KB

更新日期：2008-12-01 00:00:00

abstract：:Median convulsant (CD50) and median lethal (LD50) doses of intraperitoneal lidocaine, bupivacaine, and etidocaine were determined in 149 mice. Another 496 mice were pretreated with intramuscular diazepam, lorazepam, or midazolam, 1 mg/kg. Fifteen minutes later, lidocaine, bupivacaine, or etidocaine was given intraperi...

journal_title：Anesthesia and analgesia

authors： de Jong RH,Bonin JD

更新日期：1981-06-01 00:00:00

abstract：UNLABELLED:Spinal anesthesia is commonly used in former preterm infants (FPI). In these patients, hypotension induced by spinal anesthesia may impair cerebral blood flow. We measured cerebral blood flow velocity (CBFV) by transcranial Doppler ultrasound to assess the effect of hypotension induced by spinal anesthesia o...

journal_title：Anesthesia and analgesia

authors： Bonnet MP,Larousse E,Asehnoune K,Benhamou D

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Unicondylar knee arthroplasty (UKA) is a commonly performed procedure with significant expected postoperative pain. Peripheral nerve blocks are 1 analgesic option, but some approaches may decrease quadriceps motor strength and interfere with early ambulation. In this study, we compared the analgesia provided...

journal_title：Anesthesia and analgesia

authors： Henshaw DS,Jaffe JD,Reynolds JW,Dobson S,Russell GB,Weller RS

更新日期：2016-04-01 00:00:00

abstract：:Postoperative nausea and vomiting is common after cardiac surgery and may contribute to significant morbidity. Gastric decompression during anesthesia has been used for postoperative nausea and vomiting prophylaxis in shorter duration noncardiac surgery with conflicting results. We tested the hypothesis that gastric d...

journal_title：Anesthesia and analgesia

authors： Burlacu CL,Healy D,Buggy DJ,Twomey C,Veerasingam D,Tierney A,Moriarty DC

更新日期：2005-02-01 00:00:00

abstract：:The effect of release of intraoperative thigh tourniquets on velocity of blood flow in the middle cerebral artery was examined in five patients given general anesthesia with controlled ventilation for lower extremity orthopedic procedures using transcranial Doppler sonography. Middle cerebral artery blood flow velocit...

journal_title：Anesthesia and analgesia

authors： Hirst RP,Slee TA,Lam AM

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:Rapid establishment of a patent airway in ill or injured patients is a priority for prehospital rescue personnel. Out-of-hospital tracheal intubation can be challenging. Unrecognized esophageal intubation is a clinical disaster. METHODS:We performed an observational, prospective study of consecutive patient...

journal_title：Anesthesia and analgesia

authors： Timmermann A,Russo SG,Eich C,Roessler M,Braun U,Rosenblatt WH,Quintel M

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Adverse effects of hydroxyethyl starches (HESs) have been verified in patients suffering from sepsis or kidney disease, but not in surgical patients at large. The investigation aimed to determine whether the use of HES 130/0.4 was associated with the incidence of acute postinterventional adverse events compa...

journal_title：Anesthesia and analgesia

authors： Pagel JI,Rehm M,Kammerer T,Hulde N,Speck E,Briegel J,Reinholz F,Crispin A,Hofmann-Kiefer KF

更新日期：2018-06-01 00:00:00

abstract：:In a randomized study, we evaluated lag time (time from the end of injection of muscle relaxant until the first depression of the train-of-four response [TOF]), onset time (time from the end of injection of muscle relaxant until the maximum depression of the first twitch of the TOF [T1]), neuromuscular block, and endo...

journal_title：Anesthesia and analgesia

authors： Wierda JM,van den Broek L,Proost JH,Verbaan BW,Hennis PJ

更新日期：1993-09-01 00:00:00

abstract：UNLABELLED:As medical costs continue to escalate, there is willingness to consider the role played by nontraditional factors in health. We investigated the usefulness of tape-recorded hypnosis instruction on perioperative outcome in surgical patients in a prospective, randomized, and partially blinded study. Sixty pati...

journal_title：Anesthesia and analgesia

authors： Ghoneim MM,Block RI,Sarasin DS,Davis CS,Marchman JN

更新日期：2000-01-01 00:00:00

abstract：UNLABELLED:I designed this study to determine the efficacy of heart rate (HR), systolic blood pressure (SBP), and digital skin blood flow (DSBF) in detecting intravascular injection after a simulated epidural test dose containing 15 mug of epinephrine in sevoflurane-anesthetized adults. In addition, the testing thresho...

journal_title：Anesthesia and analgesia

authors： Mowafi HA

更新日期：2005-08-01 00:00:00

abstract：:The insertion of implantable cardioverter/defibrillators (ICD) requires induction of repeated episodes of ventricular fibrillation (VF). The neuropsychological repercussions associated with repeated inducement of hypotension and cerebral ischemia are unknown. In this prospective clinical trial, 1 day prior to ICD asse...

journal_title：Anesthesia and analgesia

authors： Murkin JM,Baird DL,Martzke JS,Yee R

更新日期：1997-06-01 00:00:00

abstract：:The extent of sensory and motor blockades was examined in 195 patients 5 and 20 min after four different techniques of brachial plexus block using 50 ml of 0.5% bupivacaine. The interscalene technique of Winnie (N = 50) resulted in a preferential blockade of the caudad portions of the cervical plexus and the cephalad ...

journal_title：Anesthesia and analgesia

authors： Lanz E,Theiss D,Jankovic D

更新日期：1983-01-01 00:00:00

abstract：:Blood levels of many medications are acutely lowered by cardiopulmonary bypass (CPB). Because nifedipine is often used to provide protection from coronary ischemia, a determination of the effect of CPB on plasma nifedipine levels might help to determine the potential clinical benefit of nifedipine during and after byp...

journal_title：Anesthesia and analgesia

authors： Katz RI,Kanchuger MS,Patton KF,Eide TR

更新日期：1990-10-01 00:00:00

abstract：:The purpose of the present study was to quantify the inhibitory effect of inhaled halothane and isoflurane on acute hypercapnia-induced responses of capacitance-regulating veins and related cardiovascular variables in response to sequential 40-s periods of 5%, 10%, 15%, and 20% inspired CO2 (FICO2). Measurements were ...

journal_title：Anesthesia and analgesia

authors： Stekiel TA,Stekiel WJ,Tominaga M,Stadnicka A,Bosnjak ZJ,Kampine JP

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:Patients with bone marrow failure and severe thrombocytopenia are frequently given prophylactic platelet transfusion before interventions. The clinical effects of such transfusions, however, are poorly defined. We performed a prospective observational study on patients with bone marrow failure scheduled for ...

journal_title：Anesthesia and analgesia

authors： Kander T,Tanaka KA,Norström E,Persson J,Schött U

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:The effect of interscalene block (ISB) on pulmonary function of obese participants has not been investigated. The goal of this study is to assess the association of obesity (body mass index [BMI] >29 kg/m vs BMI <25 kg/m) and change in forced vital capacity (FVC) and forced expiratory volume in 1 second (FEV...

journal_title：Anesthesia and analgesia

authors： Melton MS,Monroe HE,Qi W,Lewis SL,Nielsen KC,Klein SM

更新日期：2017-07-01 00:00:00

abstract：:Patients with frailty experience substantial physical and emotional distress related to their condition and face increased morbidity and mortality compared with their nonfrail peers. Palliative care is an interdisciplinary medical specialty focused on improving quality of life for patients with serious illness, includ...

journal_title：Anesthesia and analgesia

authors： Crooms RC,Gelfman LP

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:QT interval prolongation is associated with torsades des pointes (TdP), but is a poor predictor of drug torsadogenicity. Susceptibility to TdP arises from increased transmural dispersion of repolarization (TDR) across the myocardial wall, rather than QT interval prolongation per se. TDR can be measured on th...

journal_title：Anesthesia and analgesia

authors： Whyte SD,Sanatani S,Lim J,Booker PD

更新日期：2007-02-01 00:00:00

abstract：UNLABELLED:Untreated pain during the transportation of patients after minor trauma is a common problem in emergency medicine. Because paramedics usually are not allowed to perform invasive procedures or to give drugs for pain treatment, a noninvasive, nondrug-based method would be helpful. Acupressure is a traditional ...

journal_title：Anesthesia and analgesia

authors： Kober A,Scheck T,Greher M,Lieba F,Fleischhackl R,Fleischhackl S,Randunsky F,Hoerauf K

更新日期：2002-09-01 00:00:00

abstract：:The purpose of this study was to compare the perioperative effects of the intramuscular (i.m.) alpha 2 agonist, dexmedetomidine (DEX), and midazolam (MID) premedication. The study comprised 192 women (64 per group) scheduled for abdominal hysterectomy. The doses of the study drugs were chosen to obtain equal sedative ...

journal_title：Anesthesia and analgesia

authors： Erkola O,Korttila K,Aho M,Haasio J,Aantaa R,Kallio A

更新日期：1994-10-01 00:00:00

abstract：:A number of important clinical trials focusing on critically ill patients have been completed in the last few years. These trials have been among the first critical care clinical trials to demonstrate mortality reduction in the critically ill. As in any adaptation of evidence-based medicine, it is essential to closely...

journal_title：Anesthesia and analgesia

authors： Gropper MA

更新日期：2004-08-01 00:00:00

abstract：:The purpose of this canine study was to examine the cerebral vascular and metabolic effects of adding nitrous oxide to isoflurane from 1.4% expired (1 MAC) up to a concentration giving an isoelectric electroencephalogram (EEG). Cerebral blood flow (CBF) and cerebral metabolic rate for oxygen (CMRO2) were determined us...

journal_title：Anesthesia and analgesia

authors： Roald OK,Forsman M,Heier MS,Steen PA

更新日期：1991-01-01 00:00:00

abstract：:Catecholamine-induced desensitization of beta-adrenergic receptors resulting in hyporesponsiveness to further stimulation has been frequently reported after an increase in endogenous catecholamines. To examine the possibility of beta-adrenoceptor desensitization due to intraoperative adrenergic activation (surgical st...

journal_title：Anesthesia and analgesia

authors： Marty J,Nimier M,Rocchiccioli C,Mantz J,Luscombe F,Henzel D,Loiseau A,Desmonts JM

更新日期：1990-07-01 00:00:00

abstract：:Perioperative thermal manipulations are usually directed at the skin surface because methods of directly warming the core are invasive or ineffective. However, inadequate heat flow between peripheral and core compartments will decrease the rate at which core temperature changes. We therefore determined whether core hy...

journal_title：Anesthesia and analgesia

authors： Plattner O,Xiong J,Sessler DI,Schmied H,Christensen R,Turakhia M,Dechert M,Clough D

更新日期：1996-05-01 00:00:00

abstract：:In the 1930s and 1940s, photo cells permitted German, English, and American physiologists to construct ear oximeters with red and infrared light, requiring calibration. In 1940 Squire recognized that changes of red and infrared light transmission caused by pneumatic tissue compression permitted saturation to be comput...

journal_title：Anesthesia and analgesia

authors： Severinghaus JW

更新日期：2007-12-01 00:00:00