Benzodiazepines protect mice from local anesthetic convulsions and deaths.

abstract：OBJECTIVE:Through the Australian and New Zealand Haemostasis Registry, we report on the Australian and New Zealand experience with recombinant activated factor VII (rFVIIa) in obstetric patients. METHODS:The role of rFVIIa for off-label indications, including trauma, cardiac surgery, and severe postpartum hemorrhage, ...

journal_title：Anesthesia and analgesia

authors： Phillips LE,McLintock C,Pollock W,Gatt S,Popham P,Jankelowitz G,Ogle R,Cameron PA,Australian and New Zealand Haemostasis Registry.

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Preoperative flushing of an anesthesia workstation is an alternative for preparation of the anesthesia workstation before use in malignant hyperthermia-susceptible patients (MHS). We studied in vitro, using a test lung, the washout profile of sevoflurane in 7 recent workstations during adult and, for the fir...

journal_title：Anesthesia and analgesia

authors： Cottron N,Larcher C,Sommet A,Fesseau R,Alacoque X,Minville V,Fourcade O,Kern D

更新日期：2014-07-01 00:00:00

abstract：:We investigated the interaction between mivacurium and succinylcholine when mivacurium was administered during the early recovery from succinylcholine block. We studied 40 adult patients during propofol-alfentanil-N2O-O2 anesthesia. Neuromuscular function was monitored using an electromyographic method (Relaxograph, D...

journal_title：Anesthesia and analgesia

authors： Erkola O,Rautoma P,Meretoja OA

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND:Tissue factor pathway inhibitor (TFPI) is a 40-kDa, endogenous protein that inhibits tissue factor (TF)-initiated coagulation by bonding with activated factor X (FXa). The TFPI/FXa complex then subsequently binds with TF/activated factor VII (FVIIa) complex, ultimately inhibiting thrombin generation. Heparin...

journal_title：Anesthesia and analgesia

authors： Audu P,Nielsen VG,Armstead V,Powell G,Kim J,Kim L,Mehta M

更新日期：2006-10-01 00:00:00

abstract：:Previous perfluorocarbon (PFC) emulsions have been associated with transient adverse events (i.e., platelet activation, decreased platelet count, febrile responses, changes in hemodynamic function). The Phase I studies described in this report were parallel, randomized, double-blinded, placebo-controlled studies condu...

journal_title：Anesthesia and analgesia

authors： Leese PT,Noveck RJ,Shorr JS,Woods CM,Flaim KE,Keipert PE

更新日期：2000-10-01 00:00:00

abstract：UNLABELLED:We tested baicalin for its antiinflammatory and analgesic effects (and the mechanisms) in a rat model of carrageenan-evoked thermal hyperalgesia. Pre- or posttreatment with baicalin (10, 30, or 100 mg/kg intraperitoneally) caused a significant analgesic effect with a similar effect of dose-matched ibuprofen....

journal_title：Anesthesia and analgesia

authors： Chou TC,Chang LP,Li CY,Wong CS,Yang SP

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:Goal-directed fluid therapy (GDFT) is associated with improved outcomes after surgery. The esophageal Doppler monitor (EDM) is widely used, but has several limitations. The NICOM, a completely noninvasive cardiac output monitor (Cheetah Medical), may be appropriate for guiding GDFT. No prospective studies ha...

journal_title：Anesthesia and analgesia

authors： Waldron NH,Miller TE,Thacker JK,Manchester AK,White WD,Nardiello J,Elgasim MA,Moon RE,Gan TJ

更新日期：2014-05-01 00:00:00

abstract：:In addition to offering further data on the exposure of surgical and recovery-room personnel to low levels of halothane in room air, the authors demonstrate the presence of halothane levels in the blood of some surgical patients managed by other inhalation agents from machines previously used for halothane. The author...

journal_title：Anesthesia and analgesia

authors： Nicholson JA,Sada T,Aldrete JA

更新日期：1975-07-01 00:00:00

abstract：:Noma (cancrum oris) is a disease of poverty and malnutrition, which predominantly affects children younger than 10 years in developing countries. Although the majority of sufferers die of sepsis at the time of the initial infection, or of subsequent starvation due to severe trismus and an inability to eat, a small min...

journal_title：Anesthesia and analgesia

authors： Coupe MH,Johnson D,Seigne P,Hamlin B

更新日期：2013-07-01 00:00:00

abstract：:We conducted this prospective, randomized study to compare the analgesic effect of femoral nerve block and IV fentanyl administration when given to facilitate the sitting position for spinal anesthesia in patients undergoing surgery for femoral shaft fracture. Five minutes before the placement of spinal block, group F...

journal_title：Anesthesia and analgesia

authors： Sia S,Pelusio F,Barbagli R,Rivituso C

更新日期：2004-10-01 00:00:00

abstract：:The efficiency of a gravity-dependent autotransfusion system (ATS) for filtering tumor cells from blood was examined under laboratory and clinical conditions. In laboratory studies, reconstituted whole blood was seeded with known numbers of cultured A431 human vulva carcinoma cells then filtered through the ATS. Cance...

journal_title：Anesthesia and analgesia

authors： Karczewski DM,Lema MJ,Glaves D

更新日期：1994-06-01 00:00:00

abstract：:A method involving sodium fusion and analysis by fluoride electrode, which has been used for the determination of total fluorinated metabolites of fluorine-containing drugs in physiologic fluids, is shown to be inapplicable to volatile fluorinated metabolites of volatile fluorinated anesthetic agents. The yields of in...

journal_title：Anesthesia and analgesia

authors： Ivanetich KM,Bradshaw JJ,Brittain T

更新日期：1982-09-01 00:00:00

abstract：BACKGROUND:Statins have been shown to possess antiinflammatory and immunomodulatory effects. In this study, we sought to determine if preoperative statin therapy is associated with a reduced frequency of postoperative acute respiratory distress syndrome (ARDS) in surgical populations at increased risk of developing ARD...

journal_title：Anesthesia and analgesia

authors： Yadav H,Lingineni RK,Slivinski EJ,Stockler KA,Subramanian A,Oderich GS,Wigle DA,Carter RE,Kor DJ

更新日期：2014-10-01 00:00:00

abstract：:To assess the evolution of satisfactory neohepatic graft function or failure, hemodynamic variables, along with data for oxygen delivery and utilization, were analyzed retrospectively in 99 patients undergoing orthotopic liver transplantation. Caval cross-clamping without venovenous bypass initiated a series of hemody...

journal_title：Anesthesia and analgesia

authors： Steltzer H,Hiesmayr M,Tüchy G,Zimpfer M

更新日期：1993-03-01 00:00:00

abstract：:Previous in vivo studies of the coronary vascular effects of halothane (HAL) were complicated by varying hemodynamic conditions and global cardiac work demands. Accordingly, the current study evaluated changes in coronary blood flow (CBF) and associated variables during selective intracoronary administrations of HAL i...

journal_title：Anesthesia and analgesia

authors： Crystal GJ,Khoury E,Gurevicius J,Salem MR

更新日期：1995-02-01 00:00:00

abstract：BACKGROUND:Sedatives and analgesics, in doses that alter consciousness in the intensive care unit (ICU), contribute to delirium and mortality. Pain, agitation, and delirium can be monitored in ICU patients. These symptoms were noted before (PRE) and after (POST) a protocol to alleviate undesirable symptoms. Analgesia a...

journal_title：Anesthesia and analgesia

authors： Skrobik Y,Ahern S,Leblanc M,Marquis F,Awissi DK,Kavanagh BP

更新日期：2010-08-01 00:00:00

abstract：UNLABELLED:Pain on injection of propofol continues to be a problem for anesthesiologists. A lipid-free formulation of propofol and a propofol emulsion containing medium-chain triglyceride have become available in the Indian market. We performed this study to assess the pain on injection of propofol emulsion containing ...

journal_title：Anesthesia and analgesia

authors： Dubey PK,Kumar A

更新日期：2005-10-01 00:00:00

abstract：:Millions of human fetuses, infants, and children are exposed to anesthetic drugs every year in the United States and throughout the world. Anesthesia administered during critical stages of neurodevelopment has been considered safe and without adverse long-term consequences. However, recent reports provide mounting evi...

journal_title：Anesthesia and analgesia

authors： Creeley CE,Olney JW

更新日期：2010-02-01 00:00:00

abstract：UNLABELLED:Many drugs are tested intrathecally to investigate alternatives to opioids. We aimed to explore the analgesic and possible neurotoxic effects of chronic intrathecally-administered ketorolac tromethamine in rats. Catheters were placed via atlantoaxial interval in 28 Wistar rats under anesthesia of intraperito...

journal_title：Anesthesia and analgesia

authors： Korkmaz HA,Maltepe F,Erbayraktar S,Yilmaz O,Güray M,Canda MS,Günerli A,Gökmen N

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Rapid establishment of a patent airway in ill or injured patients is a priority for prehospital rescue personnel. Out-of-hospital tracheal intubation can be challenging. Unrecognized esophageal intubation is a clinical disaster. METHODS:We performed an observational, prospective study of consecutive patient...

journal_title：Anesthesia and analgesia

authors： Timmermann A,Russo SG,Eich C,Roessler M,Braun U,Rosenblatt WH,Quintel M

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:We evaluated in which anatomic layer (above the fascia [AF] or below the fascia [BF]) wound infusion of bupivacaine has the best effect on postoperative pain after abdominal hysterectomy. METHODS:Sixty-two ASA physical status I and II patients undergoing total abdominal hysterectomy and bilateral salpingo-o...

journal_title：Anesthesia and analgesia

authors： Hafizoglu MC,Katircioglu K,Ozkalkanli MY,Savaci S

更新日期：2008-12-01 00:00:00

abstract：:In this study we attempted to define the minimal dosage of alfentanil (AF) needed in combination with nitrous oxide to provide satisfactory anesthetic conditions for lower abdominal gynecologic surgery. General anesthesia was induced in 12 women with AF (150 micrograms X kg-1) and 66% N2O in O2. An infusion of AF was ...

journal_title：Anesthesia and analgesia

authors： Ausems ME,Hug CC Jr,de Lange S

更新日期：1983-11-01 00:00:00

abstract：:We studied the pharmacokinetics of thiopental enantiomers in 14 healthy patients aged 37-73 yr receiving racemic thiopental by intravenous (IV) bolus or IV infusion. Plasma concentration of each enantiomer was measured by chiral high-performance liquid chromatography. After IV bolus, the total plasma clearance (CL) (2...

journal_title：Anesthesia and analgesia

authors： Nguyen KT,Stephens DP,McLeish MJ,Crankshaw DP,Morgan DJ

更新日期：1996-09-01 00:00:00

abstract：UNLABELLED:We tested the hypothesis that, under relatively low tidal volume (VT) mechanical ventilation, continuing lung decruitment induced by negative end-expiratory pressure (NEEP) would increase the lung cytokine response, potentially contributing to lung injury. Mouse lungs were excised and randomly assigned to on...

journal_title：Anesthesia and analgesia

authors： Cheng KC,Zhang H,Lin CY,Slutsky AS

更新日期：2002-06-01 00:00:00

abstract：:The fatal/anesthetic ratio (FAR) in 44 swine weighing 32.6 +/- 0.7 kg (SEM) was determined. Fatal anesthetic concentration (the numerator for FAR) was defined as the end-tidal concentration at which the pig lived at least 10 min, during experiments that involved step increments in anesthetic concentrations. Previously...

journal_title：Anesthesia and analgesia

authors： Roberts SL,Gilbert M,Tinker JH

更新日期：1987-06-01 00:00:00

abstract：:The effects of enflurane on responses of isolated canine mesenteric arteries and veins to transmural nerve stimulation and to exogenously administered norepinephrine (a mixed alpha 1- and alpha 2-adrenoceptor agonist), phenylephrine (a selective alpha 1-adrenoceptor agonist), and tyramine were studied. The contractile...

journal_title：Anesthesia and analgesia

authors： Kobayashi Y,Yoshida K,Noguchi M,Wakasugi Y,Ito H,Okabe E

更新日期：1990-05-01 00:00:00

abstract：:Myocardial injury after noncardiac surgery (MINS) differs from myocardial infarction in being defined by troponin elevation apparently from cardiac ischemia with or without signs and symptoms. Such myocardial injury is common, silent, and strongly associated with mortality. MINS is usually asymptomatic and only detect...

journal_title：Anesthesia and analgesia

authors： Ruetzler K,Khanna AK,Sessler DI

更新日期：2020-07-01 00:00:00

abstract：:We compared in a prospective, randomized, double-blinded study the analgesic efficacy of three drugs in 120 ASA I and II patients scheduled to undergo ambulatory hand surgery with IV regional anesthesia. At discharge, oral analgesic tablets were prescribed as follows: tramadol 100 mg every 6 h, metamizol 1 g every 6 h...

journal_title：Anesthesia and analgesia

authors： Rawal N,Allvin R,Amilon A,Ohlsson T,Hallén J

更新日期：2001-02-01 00:00:00

abstract：UNLABELLED:We investigated the physiological reaction to mobilization the first and second day after aortic valve replacement in an open, prospective study. Hemodynamic and oxygenation variables were recorded in 15 patients using a pulmonary artery oximetry catheter and bench oximetry. Serious intraoperative events occ...

journal_title：Anesthesia and analgesia

authors： Kirkeby-Garstad I,Sellevold OF,Stenseth R,Skogvoll E,Karevold A

更新日期：2004-02-01 00:00:00

abstract：:The effects of different intubating doses of atracurium on the time of onset, and the effect of an additional dose of thiopental on intubating conditions, were studied in 72 patients divided into six groups (n = 12 in each). Stratified sampling was used to obtain an even sex distribution. Groups I, III, and V (control...

journal_title：Anesthesia and analgesia

authors： Naguib M,Abdulatif M,Gyasi HK,Absood GH

更新日期：1986-12-01 00:00:00