Residual halothane: Patient and personnel exposure.

abstract：:Halothane, enflurane, isoflurane, and fentanyl were examined for their potential to exacerbate liver dysfunction in rats with preexisting cirrhosis. Male Wistar rats given sodium phenobarbital for 2 weeks are assigned randomly to two groups. One group (cirrhotic) was exposed by inhalation to carbon tetrachloride (CCl4...

journal_title：Anesthesia and analgesia

authors： Baden JM,Kundomal YR,Luttropp ME Jr,Maze M,Kosek JC

更新日期：1985-12-01 00:00:00

abstract：:General anesthesia results in increases in respiratory elastance and flow resistance within 10-15 min after induction. Stabilization (compensation) of the respiratory system in the face of this added load is related to the addition of active (contractile) force-length and force-velocity properties to its internal impe...

journal_title：Anesthesia and analgesia

authors： Baydur A,Sassoon CS,Stiles CM

更新日期：1986-01-01 00:00:00

abstract：UNLABELLED:Previous investigations of the effects of potent opioid analgesics on the heart have concentrated on effects on contraction magnitude and time course, but little is known about their effects on cytosolic Ca(2+) regulation in cardiac tissue. In this study, we sought to assess the effects of alfentanil on cont...

journal_title：Anesthesia and analgesia

authors： Graham MD,Hopkins PM,Harrison SM

更新日期：2004-04-01 00:00:00

abstract：:We studied 60 nonophthalmologic patients, allocated to six treatment groups, to assess the effects of atracurium and vecuronium on intraocular pressure (IOP). All patients had IOP measured while awake, using pneumotonometry. In group 1, anesthesia was induced with thiopental, 5 mg/kg, and maintained with N2O, 70% in O...

journal_title：Anesthesia and analgesia

authors： Schneider MJ,Stirt JA,Finholt DA

更新日期：1986-08-01 00:00:00

abstract：UNLABELLED:We compared the efficacy of gas exchange during supraglottic combined-frequency jet ventilation via a jet ventilation laryngoscope and during monofrequent jet ventilation via the Mon-Jet catheter (Xomed, Jacksonville, FL). Twenty-three anesthetized (propofol, fentanyl, vecuronium) patients undergoing microla...

journal_title：Anesthesia and analgesia

authors： Bacher A,Pichler K,Aloy A

更新日期：2000-02-01 00:00:00

abstract：:The suction-biopsy channel of a flexible bronchofiberscope was used to provide subglottic jet ventilation in six dogs and eight adult human subjects. In dogs, after 75 minutes of ventilation at a driving pressure of 2580 torr/cm2 (50 lb/in2) the PaO2 was 412 +/- 18 torr and the PaCO2 32 +/- 3 torr with a peak airway p...

journal_title：Anesthesia and analgesia

authors： Satyanarayana T,Capan L,Ramanathan S,Chalon J,Turndorf H

更新日期：1980-05-01 00:00:00

abstract：UNLABELLED:We compare hemodynamic responses in normotensive and hypertensive anesthetized paralyzed patients among three intubation devices: the Macintosh laryngoscope (LS), the Trachlight lightwand (LW), and the intubating laryngeal mask airway Fastrach (ILM). Seventy-five normotensive and 75 hypertensive patients wer...

journal_title：Anesthesia and analgesia

authors： Kihara S,Brimacombe J,Yaguchi Y,Watanabe S,Taguchi N,Komatsuzaki T

更新日期：2003-03-01 00:00:00

abstract：:Qualitative arterial waveform analysis has been in existence for millennia; quantitative arterial waveform analysis techniques, which can be traced back to Euler's work in the 18th century, have not been widely used by anesthesiologists and other clinicians. This is likely attributable, in part, to the widespread use ...

journal_title：Anesthesia and analgesia

authors： Thiele RH,Durieux ME

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:A decline in emergency surgical airway procedures in recent years has resulted in a decreased exposure to cricothyrotomy. Consequently, residents have very little experience or confidence in performing this intervention. In this study, we compared cricothyrotomy skills acquired on a simple inexpensive model ...

journal_title：Anesthesia and analgesia

authors： Friedman Z,You-Ten KE,Bould MD,Naik V

更新日期：2008-11-01 00:00:00

abstract：:Critically ill patients often have cardiopulmonary perturbations that require rapid and frequent assessment for optimal care, including cardiac output determinations, measurement of cardiac filling pressures, and arterial and mixed venous blood gas determinations. We evaluated the performance of a rapid, on-demand bed...

journal_title：Anesthesia and analgesia

authors： Franklin ML,Peruzzi WT,Moen SG,Shapiro BA

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:Pulmonary complications related to residual neuromuscular blockade lead to morbidity and mortality. Using an interrupted time series design, we tested whether proportions of reintubation for respiratory failure or new noninvasive ventilation were changed after a system-wide transition of the standard reversa...

journal_title：Anesthesia and analgesia

authors： Krause M,McWilliams SK,Bullard KJ,Mayes LM,Jameson LC,Mikulich-Gilbertson SK,Fernandez-Bustamante A,Bartels K

更新日期：2020-07-01 00:00:00

abstract：:During surgery, patients are exposed to multiple foreign substances including anesthetic drugs, antibiotics, blood products, heparin, polypeptides (aprotinin, latex, and protamine), and intravascular volume expanders, which have the potential to produce life-threatening allergic reactions termed "anaphylaxis." The hal...

journal_title：Anesthesia and analgesia

authors： Levy JH,Adkinson NF Jr

更新日期：2008-02-01 00:00:00

abstract：:Ten volunteers were studied during six stages of propofol sedation, namely awake (no propofol), light sedation (small dose of propofol), deep sedation (large dose), deep sedation with stimulation of the ulnar nerve, then light sedation again (small dose), and awake (recovery). Light and deep sedation were defined in t...

journal_title：Anesthesia and analgesia

authors： Andrade J,Sapsford DJ,Jeevaratnum D,Pickworth AJ,Jones JG

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND:Malignant hyperthermia (MH) is a pharmacogenetic disorder of skeletal muscle calcium regulation associated primarily, but not exclusively, with mutations in the skeletal muscle ryanodine receptor. Associated environmental factors, however, may also be important for expression of the syndrome. METHODS AND RE...

journal_title：Anesthesia and analgesia

authors： Capacchione JF,Radimer MC,Sagel JS,Kraus GP,Sambuughin N,Muldoon SM

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Short-term case cancellation causes frustration for anesthesiologists, surgeons, and patients and leads to suboptimal use of operating room (OR) resources. In many facilities, >10% of all cases are cancelled on the day of surgery, thereby causing major problems for OR management and anesthesia departments. T...

journal_title：Anesthesia and analgesia

authors： Schuster M,Neumann C,Neumann K,Braun J,Geldner G,Martin J,Spies C,Bauer M,CASCAES Study Group.

更新日期：2011-09-01 00:00:00

abstract：:The pharmacokinetics of lidocaine were studied in nonpregnant and pregnant ewes. The maternal femoral vessels were cannulated and, on the day of study, the urinary bladder was catheterized. Lidocaine HCl, 4-5 mg/kg, was administered by IV injection over 60 seconds. Serial samples of arterial blood and urine were colle...

journal_title：Anesthesia and analgesia

authors： Santos AC,Pedersen H,Morishima HO,Finster M,Arthur GR,Covino BG

更新日期：1988-12-01 00:00:00

abstract：:Patients with frailty experience substantial physical and emotional distress related to their condition and face increased morbidity and mortality compared with their nonfrail peers. Palliative care is an interdisciplinary medical specialty focused on improving quality of life for patients with serious illness, includ...

journal_title：Anesthesia and analgesia

authors： Crooms RC,Gelfman LP

更新日期：2020-06-01 00:00:00

abstract：UNLABELLED:In this study, we compared the direct myocardial depressant effects of sevoflurane, isoflurane, and halothane and determined whether an L-type Ca2+ channel agonist, Bay K 8644, could attenuate the myocardial depression induced by these anesthetics in cultured neonatal rat ventricular myocytes. Ventricular my...

journal_title：Anesthesia and analgesia

authors： Kanaya N,Kawana S,Tsuchida H,Miyamoto A,Ohshika H,Namiki A

更新日期：1998-11-01 00:00:00

abstract：:Epidural clonidine produces analgesia in humans with acute and chronic pain. Its use is limited because of short-lasting analgesia, hemodynamic depression, sedation, and respiratory depression. Intrathecal guanfacine has a longer duration of action than intrathecal clonidine. The present study compares these two drugs...

journal_title：Anesthesia and analgesia

authors： Smith BD,Baudendistel LJ,Gibbons JJ,Schweiss JF

更新日期：1992-05-01 00:00:00

abstract：UNLABELLED:Endothelial dysfunction and platelet activation with thromboxane release may contribute to spasm or alterations in internal mammary artery (IMA) graft flow during coronary artery surgery. Clevidipine, an ultrashort-acting dihydropyridine calcium channel blocker, is undergoing clinical development, but there ...

journal_title：Anesthesia and analgesia

authors： Huraux C,Makita T,Szlam F,Nordlander M,Levy JH

更新日期：1997-11-01 00:00:00

abstract：:The nucleus raphe magnus (NRM) is an important descending pain inhibitory system. We postulated that the analgesic action of supraspinally administered opiates results from increased descending inhibitory control of the NRM. We tested whether fentanyl activates NRM neurons in the rat slice preparation using extra-cell...

journal_title：Anesthesia and analgesia

authors： Ohta Y,Alojado ME,Kemmotsu O

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:The α2-adrenergic agonist dexmedetomidine is a sedative and can be used as an adjunct to anesthetics. Our primary goal was thus to determine the extent to which dexmedetomidine reduces the requirement for propofol and remifentanil. METHODS:This double-blinded, randomized study (NCT00921284) used an automate...

journal_title：Anesthesia and analgesia

authors： Le Guen M,Liu N,Tounou F,Augé M,Tuil O,Chazot T,Dardelle D,Laloë PA,Bonnet F,Sessler DI,Fischler M

更新日期：2014-05-01 00:00:00

abstract：UNLABELLED:In this study, we examined the effectiveness of caudal blocks and correlated it with the laxity of the patients' anal sphincter before emergence from anesthesia in 178 children undergoing inguinal and/or penile surgery. Bupivacaine 0.25% in a volume of 0.6-1.25 mL/kg was used in all patients. The presence of...

journal_title：Anesthesia and analgesia

authors： Verghese ST,Mostello LA,Patel RI,Kaplan RF,Patel KM

更新日期：2002-05-01 00:00:00

abstract：UNLABELLED:This study was performed to evaluate both the effects of pentobarbital on disruption of the blood-brain barrier (BBB) by hyperosmolar mannitol and the relationship between its effect on blood pressure and the integrity of the BBB. Under isoflurane anesthesia, rats in the control group were infused with 25% m...

journal_title：Anesthesia and analgesia

authors： Chi OZ,Chun TW,Liu X,Weiss HR

更新日期：1998-06-01 00:00:00

abstract：:Adverse reactions to volatile anesthetics and depolarizing muscle relaxants can occur in patients with Duchenne muscular dystrophy (DMD) resulting in acute rhabdomyolysis and hyperkalemia. We report a case of hyperkalemic cardiac arrest after cardiac surgery using cardiopulmonary bypass in a child with unsuspected DMD...

journal_title：Anesthesia and analgesia

authors： Nathan A,Ganesh A,Godinez RI,Nicolson SC,Greeley WJ

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:Neuromuscular blocking drugs have been implicated in intraoperative bronchoconstrictive episodes. We examined the effects of clinically relevant doses of cisatracurium and rocuronium on the lung mechanics of pediatric subjects. We hypothesized that cisatracurium and rocuronium would have bronchoconstrictive ...

journal_title：Anesthesia and analgesia

authors： Yang CI,Fine GF,Jooste EH,Mutich R,Walczak SA,Motoyama EK

更新日期：2013-12-01 00:00:00

abstract：:Atelectasis is common after cardiac surgery and may result in impaired gas exchange. Continuous positive airway pressure (CPAP) is often used to prevent or treat postoperative atelectasis. We hypothesized that noninvasive pressure support ventilation (NIPSV) by increasing tidal volume could improve the evolution of at...

journal_title：Anesthesia and analgesia

authors： Pasquina P,Merlani P,Granier JM,Ricou B

更新日期：2004-10-01 00:00:00

abstract：UNLABELLED:Previous studies of samples from cranial meninges have created doubts about the existence of a virtual subdural space. We examined the ultrastructure of spinal meninges from three human cadavers immediately after death to see whether there is a virtual subdural space at this level. The arachnoid mater had tw...

journal_title：Anesthesia and analgesia

authors： Reina MA,De Leon Casasola O,López A,De Andrés JA,Mora M,Fernández A

更新日期：2002-04-01 00:00:00

abstract：UNLABELLED:To determine whether the "second gas effect" is valid, we determined the pharmacokinetics of 0.2% enflurane with or without 80% N2) (n = 7 each) under controlled constant volume ventilation in 14 young healthy male patients before their operations. The alveolar (end-tidal) concentration (FA) and inspired con...

journal_title：Anesthesia and analgesia

authors： Sun X-G,Su F,Shi YQ,Lee C

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Improving perioperative efficiency and throughput has become increasingly important in the modern practice of anesthesiology. Fast-track surgery represents a multidisciplinary approach to improving perioperative efficiency by facilitating recovery after both minor (i.e., outpatient) and major (inpatient) sur...

journal_title：Anesthesia and analgesia

authors： White PF,Kehlet H,Neal JM,Schricker T,Carr DB,Carli F,Fast-Track Surgery Study Group.

更新日期：2007-06-01 00:00:00