The effects of alfentanil on cytosolic Ca(2+) and contraction in rat ventricular myocytes.

abstract：:Regional anesthesia employing the spinal, epidural, or caudal approach was used to anesthetize 200 children, varying in age from 17 days to 15 years. Lidocaine in concentrations varying according to age was used. Ketamine (1 to 2 mg./kg.) was given in the majority of cases to ensure a quiet patient prior to block. No ...

journal_title：Anesthesia and analgesia

authors： Melman E,Penuelas JA,Marrufo J

更新日期：1975-05-01 00:00:00

abstract：:A new mode of pulmonary ventilation called intratracheal pulmonary ventilation (ITPV) was studied. Briefly, a continuous flow of air/oxygen is introduced through a small catheter, the tip of which is positioned at the carina, with a diffuser mounted at its distal end. A timed expiration valve, when closed, provides fo...

journal_title：Anesthesia and analgesia

authors： Kolobow T,Powers T,Mandava S,Aprigliano M,Kawaguchi A,Tsuno K,Mueller E

更新日期：1994-03-01 00:00:00

abstract：IMPLICATIONS:We describe a technique of one-lung high-frequency jet ventilation surgery with continuous monitoring of airway pressures that achieves satisfactory operating conditions with less complications than other similar approaches. ...

journal_title：Anesthesia and analgesia

authors： Unzueta MC,Casas I,Merten A,Landeira JM

更新日期：2003-01-01 00:00:00

abstract：:The objective of this study was to compare the success of resuscitation attempts with different cardioactive drugs after bupivacaine-induced asystole. Saline, amrinone (1 mg/kg), dopamine (5 micrograms/kg), norepinephrine (2 micrograms/kg), epinephrine (10 micrograms/kg), or isoproterenol (1 microgram/kg) were tested....

journal_title：Anesthesia and analgesia

authors： Heavner JE,Pitkänen MT,Shi B,Rosenberg PH

更新日期：1995-06-01 00:00:00

abstract：:This study was designed to determine whether preoperative administration of 6% hetastarch decreases the incidence and severity of hypotension after spinal anesthesia for cesarean section. Forty nonlaboring ASA class I and II women having nonurgent cesarean sections were randomized to receive either 500 mL of 6% hetast...

journal_title：Anesthesia and analgesia

authors： Riley ET,Cohen SE,Rubenstein AJ,Flanagan B

更新日期：1995-10-01 00:00:00

abstract：UNLABELLED:Neuronal baseline K(+) channels were activated by several volatile anesthetics. Whole-cell recordings from cultured cerebellar granule neurons of 7-day-old male Sprague-Dawley rats showed outward-rectifying K(+) currents with a conductance of approximately 1.1 +/- 0.3 nS (n = 20) at positive potentials. The ...

journal_title：Anesthesia and analgesia

authors： Shin WJ,Winegar BD

更新日期：2003-05-01 00:00:00

abstract：:Descriptive statistics are specific methods basically used to calculate, describe, and summarize collected research data in a logical, meaningful, and efficient way. Descriptive statistics are reported numerically in the manuscript text and/or in its tables, or graphically in its figures. This basic statistical tutori...

journal_title：Anesthesia and analgesia

authors： Vetter TR

更新日期：2017-11-01 00:00:00

abstract：UNLABELLED:Despite clinical and laboratory evidence of perioperative hypercoagulability, there are no consistent data evaluating the extent, duration, and specific contribution of platelets and procoagulatory proteins by in vitro testing. We tested the hypothesis that the parallel use of standard and abciximab-cytochal...

journal_title：Anesthesia and analgesia

authors： Mahla E,Lang T,Vicenzi MN,Werkgartner G,Maier R,Probst C,Metzler H

更新日期：2001-03-01 00:00:00

abstract：UNLABELLED:Evidence suggests that early postischemic hyperemia is mediated by both neurological and vascular mechanisms. We hypothesized that if neuronal activity were primarily responsible for reperfusion hyperemia, then electrocerebral silence induced by intracarotid anesthetics (propofol and pentothal) would attenua...

journal_title：Anesthesia and analgesia

authors： Joshi S,Wang M,Nishanian EV,Emerson RG

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Local anesthetics cause reversible block of pain and robustly inhibit TWIK-related K channel (TREK-1) currents. Before local anesthesia onset, injection of local anesthetics can cause unwanted transient pain. TREK-1 is an anesthetic-sensitive potassium channel that when inhibited produces pain. A disordered ...

journal_title：Anesthesia and analgesia

authors： Pavel MA,Chung HW,Petersen EN,Hansen SB

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Anesthesiologists may contribute to postoperative infections by means of the transmission of blood and pathogens to the patient and the environment in the operating room (OR). Our primary aims were to determine whether contamination of the IV hub, the anesthesia work area, and the patient could be reduced af...

journal_title：Anesthesia and analgesia

authors： Birnbach DJ,Rosen LF,Fitzpatrick M,Carling P,Arheart KL,Munoz-Price LS

更新日期：2015-11-01 00:00:00

abstract：UNLABELLED:Tropisetron is a 5-hydroxytryptamine subtype 3 receptor antagonist that is primarily used in the prevention of chemotherapy-induced nausea and vomiting. We evaluated the prophylactic effect of tropisetron on postoperative nausea and vomiting associated with epidural morphine. Dexamethasone and saline served ...

journal_title：Anesthesia and analgesia

authors： Wang JJ,Tzeng JI,Ho ST,Chen JY,Chu CC,So EC

更新日期：2002-03-01 00:00:00

abstract：:Postoperative sensitivity to tactile stimuli differs as a function of age. In this study, we hypothesized that preoperative sciatic nerve block (SNB), by providing preemptive analgesia, would result in better analgesia than postoperative SNB in the young rat. With the paw incision model of postoperative pain, male Spr...

journal_title：Anesthesia and analgesia

authors： Ririe DG,Barclay D,Prout H,Tong C,Tobin JR,Eisenach JC

更新日期：2004-07-01 00:00:00

abstract：:Sufentanil is a new synthetic opiate analgesic that is 4520 times more potent than morphine in animal experiments. This study evaluated the cardiovascular effects of sufentanil, 15 micrograms/kg, and air/O2 used as a complete anesthetic with 50% inspired oxygen (air/O2 mixture) in 40 adult patients undergoing elective...

journal_title：Anesthesia and analgesia

authors： Sebel PS,Bovil JG

更新日期：1982-02-01 00:00:00

abstract：:A quest for a systems-level neuroscientific basis of anesthetic-induced loss and return of consciousness has been in the forefront of research for the past 2 decades. Recent advances toward the discovery of underlying mechanisms have been achieved using experimental electrophysiology, multichannel electroencephalograp...

journal_title：Anesthesia and analgesia

authors： Hudetz AG,Mashour GA

更新日期：2016-11-01 00:00:00

abstract：:This study was performed to compare the efficacy of tropisetron, droperidol, and saline in the prevention of postoperative nausea and vomiting (PONV) and to compare the possible adverse effects of these drugs in gynecologic incontinence surgery. Using a randomized, double-blind study design, we studied 150 women under...

journal_title：Anesthesia and analgesia

authors： Purhonen S,Kauko M,Koski EM,Nuutinen L

更新日期：1997-03-01 00:00:00

abstract：:Fifty-three swine from the University of Missouri Sinclair Medical Research Farm were used in experimentation to determine their susceptibility to malignant hyperthermia, to determine appropriate anesthetic agents for susceptible swine and to investigate appropriate pharmaceutical agents which could protect against th...

journal_title：Anesthesia and analgesia

authors： Short CE,Paddleford RR,McGrath CJ,Williams CH

更新日期：1976-09-01 00:00:00

abstract：:The effects of different intubating doses of atracurium on the time of onset, and the effect of an additional dose of thiopental on intubating conditions, were studied in 72 patients divided into six groups (n = 12 in each). Stratified sampling was used to obtain an even sex distribution. Groups I, III, and V (control...

journal_title：Anesthesia and analgesia

authors： Naguib M,Abdulatif M,Gyasi HK,Absood GH

更新日期：1986-12-01 00:00:00

abstract：:To evaluate the effects of succinylcholine on cardiac arrhythmias and serum levels of potassium and catecholamines, dogs with hypoxia alone and with hypoxia and hypercarbia were studied during anesthesia with halothane or enflurane. After the injection of succinylcholine (0.3 mg/kg), cardiac arrhythmias occurred in al...

journal_title：Anesthesia and analgesia

authors： Leiman BC,Katz J,Butler BD

更新日期：1987-12-01 00:00:00

abstract：:Roentgenograms of iothalamate meglumine 60% (Conray) injected bilaterally into the intercostal grooves of the ninth or tenth ribs in 30 surgical patients showed extensive spread of the contrast central and peripherally from the site of injection within 30 seconds, with almost complete absorption within 10 minutes 30 s...

journal_title：Anesthesia and analgesia

authors： Moore DC,Bush WH,Scurlock JE

更新日期：1980-11-01 00:00:00

abstract：UNLABELLED:Perturbation of respiratory mechanics produced by general anesthesia and surgery is more pronounced in morbidly obese (MO) patients. Because general anesthesia induces pulmonary atelectasis in nonobese patients, we hypothesized that atelectasis formation would be particularly significant in MO patients. We i...

journal_title：Anesthesia and analgesia

authors： Eichenberger A,Proietti S,Wicky S,Frascarolo P,Suter M,Spahn DR,Magnusson L

更新日期：2002-12-01 00:00:00

abstract：UNLABELLED:Linking physiological pharmacokinetic models to models of the cardiovascular system requires knowledge of the sites in the body that mediate a drug's cardiovascular effects. We examined the role of the coronary concentrations of propofol. Nine sheep anesthetized with isoflurane (2%) were instrumented acutely...

journal_title：Anesthesia and analgesia

authors： Zheng D,Upton RN,Martinez AM

更新日期：2003-06-01 00:00:00

abstract：UNLABELLED:We describe the development and evaluation of a simple slide rule that enables the bedside determination of the infusion rate for a particular target plasma concentration of propofol. The infusion rate to reach this target concentration at time (t) is the product of the target concentration, body weight, and...

journal_title：Anesthesia and analgesia

authors： Bruhn J,Bouillon TW,Röpcke H,Hoeft A

更新日期：2003-01-01 00:00:00

abstract：UNLABELLED:The effects of heparinization and the reversal of heparin activity on platelet function after cardiopulmonary bypass have not been well defined. Flow cytometry has become a convenient and powerful technique for characterizing platelets. We examined the expression of a secretion marker (P-selectin) and an agg...

journal_title：Anesthesia and analgesia

authors： Kozek-Langenecker SA,Mohammad SF,Masaki T,Kamerath C,Cheung AK

更新日期：2000-04-01 00:00:00

abstract：:In certifying competence of anesthesiologists who have finished residency training, knowledge and judgment are evaluated objectively using written and oral examinations. Clinical motor skills, however, are not routinely assessed by objective techniques. This implicitly assumes that knowledge and judgment correlate wit...

journal_title：Anesthesia and analgesia

authors： Sivarajan M,Miller E,Hardy C,Herr G,Liu P,Willenkin R,Cullen B

更新日期：1984-06-01 00:00:00

abstract：BACKGROUND:Basic science studies suggest that perioperative immune impairment may augment the risk of cancer recurrence after otherwise potentially curative surgery. Despite its immunosuppressant properties, dexamethasone is commonly given to oncologic patients in an effort to reduce postoperative nausea and vomiting. ...

journal_title：Anesthesia and analgesia

authors： De Oliveira GS Jr,McCarthy R,Turan A,Schink JC,Fitzgerald PC,Sessler DI

更新日期：2014-06-01 00:00:00

abstract：:Catecholamine-induced desensitization of beta-adrenergic receptors resulting in hyporesponsiveness to further stimulation has been frequently reported after an increase in endogenous catecholamines. To examine the possibility of beta-adrenoceptor desensitization due to intraoperative adrenergic activation (surgical st...

journal_title：Anesthesia and analgesia

authors： Marty J,Nimier M,Rocchiccioli C,Mantz J,Luscombe F,Henzel D,Loiseau A,Desmonts JM

更新日期：1990-07-01 00:00:00

abstract：:We investigated the effects of a close carotid injection of vecuronium on changes in phrenic nerve activity during different states of oxygenation. Experiments were performed on normothermic and mechanically ventilated adult New Zealand White rabbits with a tracheostomy under continuous thiopental infusion. Carotid ar...

journal_title：Anesthesia and analgesia

authors： Wyon N,Eriksson LI,Yamamoto Y,Lindahl SG

更新日期：1996-06-01 00:00:00

abstract：:Early first-stage labor pain is primarily visceral in origin. Increasing pain intensity and transition to somatic nociceptive input characterizes late first- and second-stage labor pain. The effect of this change in nociceptive input on the duration of intrathecal labor analgesia has not been well studied. This prospe...

journal_title：Anesthesia and analgesia

authors： Viscomi CM,Rathmell JP,Pace NL

更新日期：1997-05-01 00:00:00

abstract：:Controversy exists concerning the choice of anesthetic technic for elective cesarean section. Several maternal and newborn parameters were compared during general anesthesia (GA) and lumbar epidural analgesia (LEA). High inspired maternal O2 levels were achieved with both technics. Vigorous, well-oxygenated infants wi...

journal_title：Anesthesia and analgesia

authors： James FM 3rd,Crawford JS,Hopkinson R,Davies P,Naiem H

更新日期：1977-03-01 00:00:00