The contribution of the coronary concentrations of propofol to its cardiovascular effects in anesthetized sheep.

abstract：:We measured the pharmacokinetics of hydromorphone in normal volunteers given three doses of the drug (10, 20, and 40 micrograms/kg) as intravenous 45-s injections on different days. Concentrations of hydromorphone in plasma from serial blood samples were measured by a high-performance liquid chromatography method spec...

journal_title：Anesthesia and analgesia

authors： Hill HF,Coda BA,Tanaka A,Schaffer R

更新日期：1991-03-01 00:00:00

abstract：:Cerebral computer tomography is a recently introduced neuroradiologic procedure involving tomographic x-rays of horizontal brain sections. Although most adults undergo the procedure without anesthesia, children and uncooperative adults must be given general anesthesia for absolute immobility. Of 84 procedures under ge...

journal_title：Anesthesia and analgesia

authors： Ferrer-Brechner T,Winter J

更新日期：1977-05-01 00:00:00

abstract：BACKGROUND:The recommended treatment of suspected tension pneumothorax is immediate needle decompression. Recommended sites and needle sizes for this procedure vary, and there are published reports of failed decompression as well as iatrogenic hemothorax. We investigated the optimal needle length and relative safety of...

journal_title：Anesthesia and analgesia

authors： Wax DB,Leibowitz AB

更新日期：2007-11-01 00:00:00

abstract：:Preoperative use of angiotensin-converting enzyme (ACE) inhibitors is common and has been associated with hypotension at separation from cardiopulmonary bypass (CPB). This study prospectively examined the influence of chronic preoperative ACE inhibitor use and other perioperative factors on the incidence of vasoconstr...

journal_title：Anesthesia and analgesia

authors： Tuman KJ,McCarthy RJ,O'Connor CJ,Holm WE,Ivankovich AD

更新日期：1995-03-01 00:00:00

abstract：:This study was designed to compare the efficacy of 6% hetastarch to that of crystalloid administration in reducing the incidence and severity of hypotension during spinal anesthesia. Forty ASA grade I patients scheduled for postpartum tubal ligations under spinal anesthesia were randomly allocated to receive either 50...

journal_title：Anesthesia and analgesia

authors： Sharma SK,Gajraj NM,Sidawi JE

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:A potential physicochemical interaction between epidural local anesthetics and extended-release epidural morphine (EREM) could negate the sustained release. In this study, we sought to determine the pharmacokinetic and drug effects of prior epidural lidocaine administration on EREM. METHODS:Thirty healthy w...

journal_title：Anesthesia and analgesia

authors： Atkinson Ralls L,Drover DR,Clavijo CF,Carvalho B

更新日期：2011-08-01 00:00:00

abstract：:Multiple pharmaceutical products contain excipients, or additive chemicals, to improve stability, bioavailability, antimicrobial activity, or palatability. Two of the most common excipients are propylene glycol and parabens. We report the successful anesthetic management of a patient with idiosyncratic reactions to pr...

journal_title：Anesthesia and analgesia

authors： Farber MK,Angelo TE,Castells M,Tsen LC

更新日期：2010-03-01 00:00:00

abstract：:We considered the allocation of operating room (OR) time at facilities where the strategic decision had been made to increase the number of ORs. Allocation occurs in two stages: a long-term tactical stage followed by short-term operational stage. Tactical decisions, approximately 1 yr in advance, determine what specia...

journal_title：Anesthesia and analgesia

authors： Dexter F,Ledolter J,Wachtel RE

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:In this study we sought to determine whether the topographical measurement along the course of the central veins can estimate the approximate insertion depths of central venous catheters (CVC). METHODS:Two hundred central venous catheterizations were performed via the right and left internal jugular vein (I...

journal_title：Anesthesia and analgesia

authors： Kim MC,Kim KS,Choi YK,Kim DS,Kwon MI,Sung JK,Moon JY,Kang JM

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Some drugs used for sedation and anesthesia produce histopathologic central nervous system changes in juvenile animal models. These observations have raised concerns regarding the use of these drugs in pediatric patients. We summarized the findings in developing animals and describe the steps that the Food a...

journal_title：Anesthesia and analgesia

authors： Mellon RD,Simone AF,Rappaport BA

更新日期：2007-03-01 00:00:00

abstract：:In recent years the off-label use of recombinant activated factor VII (rFVIIa) has markedly increased, particularly in pediatric cardiac surgery patients, and practitioners differ widely in their usage of the drug. In 2009, the Congenital Cardiac Anesthesia Society (CCAS) assembled a task force to review the literatur...

journal_title：Anesthesia and analgesia

authors： Guzzetta NA,Russell IA,Williams GD

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Transversus abdominis plane (TAP) block and local anesthetic wound infiltration provide analgesia after cesarean delivery. Studies comparing the 2 techniques are scarce, with conflicting results. This double-blind, randomized controlled trial aimed to compare bilateral ultrasound-guided TAP block with single...

journal_title：Anesthesia and analgesia

authors： Tawfik MM,Mohamed YM,Elbadrawi RE,Abdelkhalek M,Mogahed MM,Ezz HM

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Postoperative nausea (PON) is a common complication of anesthesia and surgery. Antiemetic medication for higher-risk patients may reduce but does not reliably prevent PON. We examined aromatherapy as a treatment for patients experiencing PON after ambulatory surgery. Our primary hypothesis was that in compar...

journal_title：Anesthesia and analgesia

authors： Hunt R,Dienemann J,Norton HJ,Hartley W,Hudgens A,Stern T,Divine G

更新日期：2013-09-01 00:00:00

abstract：:The anesthetic effect of lidocaine was evaluated in rats by determining the change in anesthetic requirement of cyclopropane MAC that was produced by blood concentrations of lidocaine in the clinically useful range. A linear reduction in anesthetic requirement was produced with concentrations up to 1 mug/ml. Further i...

journal_title：Anesthesia and analgesia

authors： DiFazio CA,Neiderlehner JR,Burney RG

更新日期：1976-11-01 00:00:00

abstract：BACKGROUND:Several data suggest that both opioid and N-methyl-d-aspartate (NMDA) receptors are localized at the peripheral level, and drugs acting on these receptors may produce antinociception after topical administration; however, the antinociceptive effect of endogenous ligands at these receptors is poorly clarified...

journal_title：Anesthesia and analgesia

authors： Mecs L,Tuboly G,Nagy E,Benedek G,Horvath G

更新日期：2009-10-01 00:00:00

abstract：:We studied 60 children undergoing elective surgery to evaluate the effect of interactions between vecuronium and isoflurane or halothane on the potency and duration of neuromuscular blockade, as measured by electromyography. Vecuronium was first administered by a logarithm-based cumulative method (14, 22, 35, 56, 89 m...

journal_title：Anesthesia and analgesia

authors： Pittet JF,Melis A,Rouge JC,Morel DR,Gemperle G,Tassonyi E

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:In vivo animal assays are a cornerstone of preclinical pain research. An optimal stimulus for determining the activity of potential analgesics would produce responses of a consistent magnitude on repeated testing. Intraplantar (i.pl.) injection of hypertonic saline (HS) in mice produces robust nociceptive re...

journal_title：Anesthesia and analgesia

authors： Asiri YI,Fung T,Schwarz SKW,Barr AM,Puil E,MacLeod BA

更新日期：2019-07-01 00:00:00

abstract：:Cytokine release during surgery can produce a long-lasting hyperalgesia. Thus, preoperatively-administered cytokine inhibitors might reduce the production of cytokines, decreasing central nervous system sensitization and improving the quality of postoperative pain relief. We investigated the hypothesis that preincisio...

journal_title：Anesthesia and analgesia

authors： Lu CH,Chao PC,Borel CO,Yang CP,Yeh CC,Wong CS,Wu CT

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Calmodulin (CaM) activation by Ca(2+), its translocation to the nucleus, and stimulation of phosphorylation of cyclic adenosine monophosphate response element-binding protein (CREB) (P-CREB) are necessary for new gene expression and have been linked to long-term potentiation, a process important in memory fo...

journal_title：Anesthesia and analgesia

authors： Zhang J,Sutachan JJ,Montoya-Gacharna J,Xu CF,Xu F,Neubert TA,Recio-Pinto E,Blanck TJ

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Recent research suggests that 6% hydroxyethyl starch (HES) 130/0.4 is one of the most frequently used resuscitation fluids worldwide. The retraction of studies evaluating its use necessitates a reevaluation of available evidence regarding its safety and efficacy. METHODS:We performed a systematic review and...

journal_title：Anesthesia and analgesia

authors： Gattas DJ,Dan A,Myburgh J,Billot L,Lo S,Finfer S,CHEST Management Committee.

更新日期：2012-01-01 00:00:00

abstract：UNLABELLED:One-lung ventilation (OLV) induces an increase in pulmonary shunt sometimes associated with a decrease in PaO2 despite ventilation with 100% oxygen. PaO2 improvement has been reported in one-lung ventilated animals receiving IV almitrine, a pulmonary vasoconstrictor. We evaluated the ability of almitrine to ...

journal_title：Anesthesia and analgesia

authors： Moutafis M,Dalibon N,Liu N,Kuhlman G,Fischler M

更新日期：2002-04-01 00:00:00

abstract：:The alpha 2-adrenergic receptor agonist dexmedetomidine produces an anesthetic state in a variety of species. Although its effects on cerebral blood flow and the electroencephalogram have been investigated, the effect of this drug on intracranial pressure (ICP) has not been reported previously. Dexmedetomidine therefo...

journal_title：Anesthesia and analgesia

authors： Zornow MH,Scheller MS,Sheehan PB,Strnat MA,Matsumoto M

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:Platelet factor 4 (PF4) is released by activated platelets and has a strong affinity for heparin. Recombinant PF4 (rPF4) has been previously considered as an alternative to protamine for heparin reversal. However, it has been demonstrated that antibodies directed against the PF4/heparin moiety are important ...

journal_title：Anesthesia and analgesia

authors： Demma L,Levy JH

更新日期：2012-12-01 00:00:00

abstract：:The advantages of laparoscopic over open surgery have been documented in nonblinded settings. Our prospective, double-blind setting evaluated pain scores 72 h after surgery by comparing patients who underwent laparoscopic myomectomy or with laparotomy. Forty women referred for conservative myomectomy were included in ...

journal_title：Anesthesia and analgesia

authors： Holzer A,Jirecek ST,Illievich UM,Huber J,Wenzl RJ

更新日期：2006-05-01 00:00:00

abstract：UNLABELLED:Although acute tolerance to analgesia develops rapidly with remifentanil, it is unknown whether acute tolerance also develops to its nonanalgesic effects. We investigated the analgesic and cardiorespiratory effects of remifentanil during a continuous infusion in a rabbit model. Ten tracheotomized New Zealand...

journal_title：Anesthesia and analgesia

authors： Hayashida M,Fukunaga A,Hanaoka K

更新日期：2003-11-01 00:00:00

abstract：UNLABELLED:Hypothermia after induction of general anesthesia results largely from core-to-peripheral redistribution of body heat. Both central inhibition of tonic thermoregulatory vasoconstriction in arteriovenous shunts and anesthetic-induced arteriolar and venous dilation contribute to this redistribution. Ketamine, ...

journal_title：Anesthesia and analgesia

authors： Ikeda T,Kazama T,Sessler DI,Toriyama S,Niwa K,Shimada C,Sato S

更新日期：2001-10-01 00:00:00

abstract：UNLABELLED:Uptake of inhaled anesthetics may be measured as the amount of anesthetic infused to maintain a constant alveolar concentration of anesthetic. This method assumes that the patient absorbs all of the infused anesthetic, and that none is lost to circuit components. Using a standard anesthetic circuit with a 3-...

journal_title：Anesthesia and analgesia

authors： Eger EI 2nd,Ionescu P,Gong D

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:Pulmonary complications related to residual neuromuscular blockade lead to morbidity and mortality. Using an interrupted time series design, we tested whether proportions of reintubation for respiratory failure or new noninvasive ventilation were changed after a system-wide transition of the standard reversa...

journal_title：Anesthesia and analgesia

authors： Krause M,McWilliams SK,Bullard KJ,Mayes LM,Jameson LC,Mikulich-Gilbertson SK,Fernandez-Bustamante A,Bartels K

更新日期：2020-07-01 00:00:00

abstract：IMPLICATIONS:Chronic hiccups may be a serious therapeutic problem. Pharmacological treatment with increasing dosages of baclofen, carbamazepine, or gabapentin is not always successful. In this paper, the use of general anesthesia with positive-pressure ventilation and muscle relaxation for the termination of chronic hi...

journal_title：Anesthesia and analgesia

authors： Lierz P,Felleiter P

更新日期：2002-08-01 00:00:00

abstract：:Myocardial injury after noncardiac surgery (MINS) differs from myocardial infarction in being defined by troponin elevation apparently from cardiac ischemia with or without signs and symptoms. Such myocardial injury is common, silent, and strongly associated with mortality. MINS is usually asymptomatic and only detect...

journal_title：Anesthesia and analgesia

authors： Ruetzler K,Khanna AK,Sessler DI

更新日期：2020-07-01 00:00:00