Pharmacokinetics of lidocaine in nonpregnant and pregnant ewes.

abstract：:Persistent postoperative opioid use is thought to contribute to the ongoing opioid epidemic in the United States. However, efforts to study and address the issue have been stymied by the lack of a standard definition, which has also hampered efforts to measure the incidence of and risk factors for persistent postopera...

journal_title：Anesthesia and analgesia

authors： Kent ML,Hurley RW,Oderda GM,Gordon DB,Sun E,Mythen M,Miller TE,Shaw AD,Gan TJ,Thacker JKM,McEvoy MD,POQI-4 Working Group.

更新日期：2019-08-01 00:00:00

abstract：UNLABELLED:Whether tracheal intubation is more difficult in obese patients is debatable. We compared the incidence of difficult tracheal intubation in obese and lean patients by using a recently validated objective scale, the intubation difficulty scale (IDS). We studied 134 lean (body mass index, <30 kg/m2) and 129 ob...

journal_title：Anesthesia and analgesia

authors： Juvin P,Lavaut E,Dupont H,Lefevre P,Demetriou M,Dumoulin JL,Desmonts JM

更新日期：2003-08-01 00:00:00

abstract：:Practicing anesthesiologists are at high risk of hepatitis B infection, but the risk for anesthesia residents has not been assessed. Anesthesia residents at seven universities were surveyed to study the epidemiology of hepatitis B in these trainees. Hepatitis B virus markers in serum were measured and data from questi...

journal_title：Anesthesia and analgesia

authors： Berry AJ,Isaacson IJ,Kane MA,Schatz GC,Clark BT,Beaupre P,Derrer S,Kapur P,Thompson J,Martin D

更新日期：1985-07-01 00:00:00

abstract：BACKGROUND:Premedication with midazolam is commonly used in children to reduce anxiety and improve cooperation before anesthesia. However, it has the potential to alter respiratory function because of its muscle relaxant properties. We assessed functional residual capacity (FRC), ventilation homogeneity, using a lung c...

journal_title：Anesthesia and analgesia

authors： von Ungern-Sternberg BS,Erb TO,Habre W,Sly PD,Hantos Z

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Aspects of intraoperative management (eg, hypotension) are associated with acute kidney injury (AKI) in noncardiac surgery patients. However, it is unclear if and how the addition of intraoperative data affects a baseline risk prediction model for postoperative AKI. METHODS:With institutional review board (...

journal_title：Anesthesia and analgesia

authors： Kim M,Li G,Mohan S,Turnbull ZA,Kiran RP,Li G

更新日期：2021-02-01 00:00:00

abstract：:Primary sensory nerves transmit information to both the periphery and central nervous systems, and they mediate neurogenic inflammation by release of neurotransmitters, such as tachykinins, in the periphery. Because the effect of local anesthetics on neurogenic inflammation is a subject of controversy, we investigated...

journal_title：Anesthesia and analgesia

authors： Takakura K,Mizogami M,Morishima S,Muramatsu I

更新日期：2006-09-01 00:00:00

abstract：:Hemispheric synchronization is currently promoted as a treatment for preoperative anxiety and for reduction of intraoperative anesthetic and analgesic consumption. We designed this study to examine the effect of Hemisync sounds on anesthetic hypnotic depth. After obtaining informed consent, we randomized subjects unde...

journal_title：Anesthesia and analgesia

authors： Dabu-Bondoc S,Drummond-Lewis J,Gaal D,McGinn M,Caldwell-Andrews AA,Kain ZN

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Drugs such as propofol and ketamine are used alone or in combination to provide sedation for medical procedures in children. The purpose of this systematic review was to compare the safety and effectiveness of propofol and ketamine to other drug regimens. METHODS:We searched Medline, Embase, Cochrane Centra...

journal_title：Anesthesia and analgesia

authors： Hayes JA,Aljuhani T,De Oliveira K,Johnston BC

更新日期：2020-07-07 00:00:00

abstract：BACKGROUND:Transfusion-related acute lung injury (TRALI) and transfusion-associated circulatory overload (TACO) are the leading causes of transfusion-related fatalities. While these transfusion-related pulmonary complications (TRPCs) have been well detailed in adults, their burden in pediatric subsets remains poorly de...

journal_title：Anesthesia and analgesia

authors： Thalji L,Thum D,Weister TJ,Weber WV,Stubbs JR,Kor DJ,Nemergut ME

更新日期：2018-11-01 00:00:00

abstract：:This study documented gastric fluid acidity in ambulatory surgical patients 30-120 min after they had taken a 300-mg tablet of ranitidine, as changes specific to this relatively brief dose-to-sampling interval previously had not been delineated. At 20-120 min before outpatient surgery, ranitidine was given with 15 mL ...

journal_title：Anesthesia and analgesia

authors： Jacobs BR,Swift CA,Dubow HD,Kosarussavadi B,McGoldrick K,O'Connor TZ,Silverman DG

更新日期：1991-12-01 00:00:00

abstract：:We compared intrathecal ropivacaine to bupivacaine in patients scheduled for transurethral resection of bladder or prostate. Doses of ropivacaine and bupivacaine were chosen according to a 3:2 ratio found to be equipotent in orthopedic surgery. One hundred patients were randomly assigned to blindly receive either 10 m...

journal_title：Anesthesia and analgesia

authors： Malinovsky JM,Charles F,Kick O,Lepage JY,Malinge M,Cozian A,Bouchot O,Pinaud M

更新日期：2000-12-01 00:00:00

abstract：UNLABELLED:Thiopental is a racemate. In this study, we examined whether thiopental total body clearance and its distribution into central nervous system (CNS) tissue of rats was enantioselective. Rats, either anesthetized with halothane or conscious and restrained, were infused to stepwise steady-state targets of 5, 10...

journal_title：Anesthesia and analgesia

authors： Mather LE,Edwards SR,Duke CC,Cousins MJ

更新日期：1999-07-01 00:00:00

abstract：UNLABELLED:Evidence suggests that early postischemic hyperemia is mediated by both neurological and vascular mechanisms. We hypothesized that if neuronal activity were primarily responsible for reperfusion hyperemia, then electrocerebral silence induced by intracarotid anesthetics (propofol and pentothal) would attenua...

journal_title：Anesthesia and analgesia

authors： Joshi S,Wang M,Nishanian EV,Emerson RG

更新日期：2004-05-01 00:00:00

abstract：UNLABELLED:We investigated the direct effects of midazolam and diazepam on cardiac excitation-contraction coupling in adult rat ventricular myocytes. Freshly isolated rat ventricular myocytes were loaded with fura-2/AM and field-stimulated at 28 degrees C. Intracellular Ca(2+) transients (340:380 ratio) and myocyte sho...

journal_title：Anesthesia and analgesia

authors： Kanaya N,Murray PA,Damron DS

更新日期：2002-12-01 00:00:00

abstract：UNLABELLED:The availability of an analgesic compound devoid of the side effects associated with the commonly used opioid and nonsteroidal antiinflammatory drugs would be useful during the perioperative period. Although adenosine has analgesic and anesthetic-sparing properties, it also produces dose-dependent cardiovasc...

journal_title：Anesthesia and analgesia

authors： Wang B,Tang J,White PF,Foster AC,Grettenberger HM,Kopcho J,Wender RH

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:Control of bleeding during laparoscopic liver resection (LLR) is important for patient safety. It remains unknown what the effects of mechanical ventilation with varying tidal volumes on bleeding during LLR. Thus, this study aims to investigate whether mechanical ventilation with low tidal volume (LTV) reduc...

journal_title：Anesthesia and analgesia

authors： Gao X,Xiong Y,Huang J,Zhang N,Li J,Zheng S,Lu K,Ma D,Yang B,Ning J

更新日期：2020-10-14 00:00:00

abstract：BACKGROUND:Asian American/Pacific Islanders (AAPIs) are the fastest-growing racial group in the United States. Despite a higher socioeconomic status, AAPI women experience higher rates of maternal morbidity and mortality. METHODS:Using the National Inpatient Sample, we performed a retrospective cohort analysis of wome...

journal_title：Anesthesia and analgesia

authors： Siddiqui M,Minhaj M,Mueller A,Tung A,Scavone B,Rana S,Shahul S

更新日期：2017-03-01 00:00:00

abstract：:In a randomized, double-blind, placebo-controlled trial, we evaluated the use of preoperative local anesthesia with regard to postoperative pain. Before surgery in 66 patients scheduled for cholecystectomy, the abdominal wall along the proposed line of incision was infiltrated with 70 mL of 0.25% ropivacaine, 70 mL of...

journal_title：Anesthesia and analgesia

authors： Johansson B,Glise H,Hallerbäck B,Dalman P,Kristoffersson A

更新日期：1994-02-01 00:00:00

abstract：UNLABELLED:Using a randomized, double-blind protocol design, we compared a new lower-lipid emulsion of propofol (Ampofol) containing propofol 1%, soybean oil 5%, and egg lecithin 0.6% with the most commonly used formulation of propofol (Diprivan) with respect to onset of action and recovery profiles, as well as intraop...

journal_title：Anesthesia and analgesia

authors： Song D,Hamza M,White PF,Klein K,Recart A,Khodaparast O

更新日期：2004-03-01 00:00:00

abstract：:A recognized side effect of chemonucleolysis is life-threatening anaphylaxis to chymopapain. In the clinical trials of chymopapain, 13 cases of anaphylaxis were reported in 1585 administrations (0.82%). Two patients died. Data from a postmarketing survey (48,239 questionnaires) were reviewed to identify factors influe...

journal_title：Anesthesia and analgesia

authors： Moss J,Roizen MF,Nordby EJ,Thisted R,Apfelbaum JL,Schreider BD,McDermott DJ

更新日期：1985-12-01 00:00:00

abstract：UNLABELLED:As the surgical population ages, the number of patients presenting with coronary artery disease and age-related loss of pulmonary recoil will increase. Although their influence on gas exchange in this population remains unknown, sevoflurane and isoflurane are used for an increasing variety of surgical proced...

journal_title：Anesthesia and analgesia

authors： Loeckinger A,Keller C,Lindner KH,Kleinsasser A

更新日期：2002-05-01 00:00:00

abstract：UNLABELLED:The Valsalva maneuver in the awake patient and the ventilation maneuver in the tracheally intubated anesthetized patient are two provocation methods to detect a patent foramen ovale (PFO) by means of contrast transesophageal echocardiography. In 60 patients undergoing posterior fossa surgery, a contrast agen...

journal_title：Anesthesia and analgesia

authors： Greim CA,Trautner H,Krämer K,Zimmermann P,Apfel CC,Roewer N

更新日期：2001-05-01 00:00:00

abstract：:A pharmacokinetic evaluation of bupivacaine was carried out after intercostal nerve blocks performed on 28 occasions in 27 children varying in age from 3 months to 16 yr. Bupivacaine HCl, 0.5%, with epinephrine 1:200,000 was employed. Doses of 2 mg/kg, 3 mg/kg, and 4 mg/kg resulted in peak whole blood arterial bupivac...

journal_title：Anesthesia and analgesia

authors： Rothstein P,Arthur GR,Feldman HS,Kopf GS,Covino BG

更新日期：1986-06-01 00:00:00

abstract：BACKGROUND:A lighted stylet is an effective alternative to a direct laryngoscope and has been reported to be particularly useful in patients with difficult airways. A high Mallampati class indicates poor visibility of the oropharyngeal structures. Because a lighted stylet does not require direct oropharyngeal visualiza...

journal_title：Anesthesia and analgesia

authors： Rhee KY,Lee JR,Kim J,Park S,Kwon WK,Han S

更新日期：2009-04-01 00:00:00

abstract：:This study examined anesthetic development and hemodynamic changes during two techniques of hyperbaric lidocaine administration through 27-gauge intrathecal catheters for continuous spinal anesthesia in 55 elderly patients undergoing transurethral prostatic resection. Twenty-five patients were randomly assigned to rec...

journal_title：Anesthesia and analgesia

authors： Chan VW,Chung F,Gomez M,Seyone C,Baylon G

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:The combination of propofol-remifentanil for procedural deep sedation in spontaneously breathing patients is characterized by the frequent incidence of side effects, especially respiratory depression. These side effects may be due to either the drug combination or the drug delivery technique. Target-controll...

journal_title：Anesthesia and analgesia

authors： Moerman AT,Herregods LL,De Vos MM,Mortier EP,Struys MM

更新日期：2009-03-01 00:00:00

abstract：UNLABELLED:We studied the effect of fluvoxamine and erythromycin on the pharmacokinetics of ropivacaine in a double-blinded, randomized, four-way cross-over study. Eight healthy volunteers ingested daily 1500 mg erythromycin for 6 days, 100 mg fluvoxamine for 5 days (Days 2-6), both erythromycin and fluvoxamine, or pla...

journal_title：Anesthesia and analgesia

authors： Jokinen MJ,Ahonen J,Neuvonen PJ,Olkkola KT

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:District-level hospitals (DLHs) are the main providers of surgical services for rural populations in Sub-Saharan Africa (SSA). Skilled teams are essential for surgical care, and gaps in anesthesia impact negatively on surgical capacity and outcomes. This study, from a baseline of a project scaling-up access ...

journal_title：Anesthesia and analgesia

authors： Gajewski J,Pittalis C,Lavy C,Borgstein E,Bijlmakers L,Mwapasa G,Cheelo M,Le G,Juma A,Kachimba J,Marealle P,Mkandawire N,Chilonga K,Brugha R

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:We compared two antiemetic prophylaxis regimens, their efficacy for preventing postdischarge nausea and vomiting, and their impact on quality of living, during recovery. METHODS:Sixty-four women undergoing outpatient gynecological surgery and at high risk for emesis were randomized into one of two groups. T...

journal_title：Anesthesia and analgesia

authors： Pan PH,Lee SC,Harris LC

更新日期：2008-08-01 00:00:00

abstract：:During Gram-negative sepsis, endotoxin lipopolysaccharide (LPS) may activate host inflammatory responses, resulting in the systemic inflammatory response syndrome and the adult respiratory distress syndrome. In cell culture systems, LPS activation of cellular responses may be potentiated by plasma proteins. In the iso...

journal_title：Anesthesia and analgesia

authors： Goldsmith JA,Kavanagh BP,Pearl RG

更新日期：1996-08-01 00:00:00