Time required for oral ranitidine to decrease gastric fluid acidity.

abstract：BACKGROUND:In this study we sought to determine and compare the minimum local anesthetic volumes (MLAV) and doses (MLAD) of two concentrations of bupivacaine for epidural pain relief in labor, and to quantify the effect on dose. METHODS:Eighty women were randomized in a double-blind manner to receive a first bolus of ...

journal_title：Anesthesia and analgesia

authors： Lyons GR,Kocarev MG,Wilson RC,Columb MO

更新日期：2007-02-01 00:00:00

abstract：UNLABELLED:We conducted a prospective, randomized study to determine the efficacy of conjugated estrogen in reducing blood product transfusion during orthotopic liver transplantation (OLT). Patients undergoing OLT were included in the study. Only those having a reaction time of more than 30 mm or 15 min (19 -28 mm) on ...

journal_title：Anesthesia and analgesia

authors： Frenette L,Cox J,McArdle P,Eckhoff D,Bynon S

更新日期：1998-06-01 00:00:00

abstract：:Despite a half century of research and the implementation of various risk-reduction strategies among clinicians and basic scientists, patients continue to experience strokes and cognitive dysfunction related to the use of cardiopulmonary bypass (CPB) for cardiac surgery. One strategy to reduce these detrimental effect...

journal_title：Anesthesia and analgesia

authors： Grigore AM,Murray CF,Ramakrishna H,Djaiani G

更新日期：2009-12-01 00:00:00

abstract：UNLABELLED:We compared the effectiveness of ondansetron, dimenhydrinate, and placebo for the prevention of postoperative vomiting in children after adenotonsillectomy. In a randomized, placebo-controlled, double-blind study, 74 children, 2-10 yr of age scheduled for adenotonsillectomy as outpatients were given a single...

journal_title：Anesthesia and analgesia

authors： Hamid SK,Selby IR,Sikich N,Lerman J

更新日期：1998-03-01 00:00:00

abstract：:An in vitro model was used to determine the force required to pierce bovine dura with a range of new spinal needles and to measure the subsequent leakage rate of cerebrospinal fluid (CSF). A significantly greater force was required to pierce the dura with pencil-point style needles compared to Quincke needles of the s...

journal_title：Anesthesia and analgesia

authors： Westbrook JL,Uncles DR,Sitzman BT,Carrie LE

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Individualizing arterial blood pressure (ABP) targets during cardiopulmonary bypass (CPB) based on cerebral blood flow (CBF) autoregulation monitoring may provide a more effective means for preventing cerebral hypoperfusion than the current standard of care. Autoregulation can be monitored in real time with ...

journal_title：Anesthesia and analgesia

authors： Ono M,Zheng Y,Joshi B,Sigl JC,Hogue CW

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Hyperkalemia poses serious hazards to patients undergoing orthotopic liver transplantation (OLT), and its predictors have not been thoroughly examined. METHODS:We retrospectively studied 1124 consecutive adult patients who underwent OLT. Hyperkalemia was defined as serum K+ > or =5.5 mmol/L. A total of 47 r...

journal_title：Anesthesia and analgesia

authors： Xia VW,Ghobrial RM,Du B,Chen T,Hu KQ,Hiatt JR,Busuttil RW,Steadman RH

更新日期：2007-09-01 00:00:00

abstract：:Cardiopulmonary bypass (CPB) impairs pulmonary endothelial injury in part by increasing expression of adhesion molecules that results in neutrophil influx. Although numerous proinflammatory cytokines up-regulate these responses, the extent to which systemic and pulmonary proinflammatory cytokines increase remains unkn...

journal_title：Anesthesia and analgesia

authors： Kotani N,Hashimoto H,Sessler DI,Muraoka M,Wang JS,O'Connor MF,Matsuki A

更新日期：2000-05-01 00:00:00

abstract：:The importance of timely administration of antibiotics for prophylaxis of surgical site infections has led to pressure on anesthesiologists to administer antibiotics. We present a survey of members of the American Association of Clinical Directors designed to evaluate the role of the anesthesiologist in the selection ...

journal_title：Anesthesia and analgesia

authors： Warters RD,Szmuk P,Pivalizza EG,Gebhard RE,Katz J,Ezri T,American Association of Clinical Directors.

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:We have shown previously that either echocardiographic indices of diastolic dysfunction or increased preoperative brain natriuretic peptide (BNP) predict postoperative atrial fibrillation (POAF). Because these 2 predictors of POAF have not been evaluated together, our goal was to further elucidate their conc...

journal_title：Anesthesia and analgesia

authors： Brecher O,Gulati H,Roistacher N,Zhang H,Shi W,Thaler HT,Amar D

更新日期：2017-04-01 00:00:00

abstract：UNLABELLED:The use of cerebral monitoring may improve the ability of anesthesiologists to titrate anesthetic drugs. However, there is controversy regarding the impact of the alleged anesthetic-sparing effects of cerebral monitoring on the recovery process and patient outcome. We designed this prospective double-blinded...

journal_title：Anesthesia and analgesia

authors： Recart A,Gasanova I,White PF,Thomas T,Ogunnaike B,Hamza M,Wang A

更新日期：2003-12-01 00:00:00

abstract：UNLABELLED:Volatile anesthetics attenuate baroreflex function in a concentration-dependent manner. This study was designed to determine how long full recovery of baroreflex control of heart rate takes after isoflurane or sevoflurane anesthesia in healthy volunteers. We assessed baroreflex sensitivity in 20 subjects ran...

journal_title：Anesthesia and analgesia

authors： Nagasaki G,Tanaka M,Nishikawa T

更新日期：2001-11-01 00:00:00

abstract：:A guinea pig model of halothane hepatitis was used to explore the humoral immune response induced by multiple halothane exposures and the potential role this response might play in contributing to liver damage. Three different strains of guinea pigs (Strain 2, Amana, and Hartley) were exposed to 1% halothane under eit...

journal_title：Anesthesia and analgesia

authors： Siadat-Pajouh M,Hubbard AK,Roth TP,Gandolfi AJ

更新日期：1987-12-01 00:00:00

abstract：:We examined the effect of halothane and isoflurane on contraction in the vascular smooth muscle of rat thoracic aorta simultaneously with the cytosolic Ca2+ levels ([Ca2+]i). Isolated spiral strips of rat thoracic aorta were suspended for isometric tension recordings in physiologic salt solution. The [Ca2+]i was measu...

journal_title：Anesthesia and analgesia

authors： Tsuchida H,Namba H,Seki S,Fujita S,Tanaka S,Namiki A

更新日期：1994-06-01 00:00:00

abstract：:We studied the pharmacokinetics of thiopental enantiomers in 14 healthy patients aged 37-73 yr receiving racemic thiopental by intravenous (IV) bolus or IV infusion. Plasma concentration of each enantiomer was measured by chiral high-performance liquid chromatography. After IV bolus, the total plasma clearance (CL) (2...

journal_title：Anesthesia and analgesia

authors： Nguyen KT,Stephens DP,McLeish MJ,Crankshaw DP,Morgan DJ

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:Signal transduction cascade of anesthetic-induced preconditioning has been extensively studied, yet many aspects of it remain unsolved. Here, we investigated the roles of reactive oxygen species (ROS) and mitochondrial uncoupling in cardiomyocyte preconditioning by two modern volatile anesthetics: desflurane...

journal_title：Anesthesia and analgesia

authors： Sedlic F,Pravdic D,Ljubkovic M,Marinovic J,Stadnicka A,Bosnjak ZJ

更新日期：2009-08-01 00:00:00

abstract：:In pregnant patients with myasthenia gravis and respiratory compromise, neuraxial anesthesia for lower abdominal surgery can risk further respiratory depression. We report the use of epidural anesthesia for dilation and curettage and tubal ligation in a 26-yr-old woman with a 12-wk intrauterine pregnancy with severe m...

journal_title：Anesthesia and analgesia

authors： Warren J,Sharma SK

更新日期：2006-03-01 00:00:00

abstract：UNLABELLED:To evaluate the efficacy and acceptance of a new posterior subgluteus approach to the sciatic nerve, as compared with the classic posterior approach, 128 patients undergoing foot orthopedic procedures were randomly allocated to receive either the classic posterior sciatic nerve block (Group Labat, n = 64) or...

journal_title：Anesthesia and analgesia

authors： di Benedetto P,Bertini L,Casati A,Borghi B,Albertin A,Fanelli G

更新日期：2001-10-01 00:00:00

abstract：:We investigated the efficacy of granisetron and dolasetron in preventing postoperative nausea and vomiting. Because the metabolism of the various antiemetic 5-hydroxytryptamine type 3 (5-HT3) antagonists involves different isoforms of the hepatic cytochrome P450 system, we examined the relationship between the clinica...

journal_title：Anesthesia and analgesia

authors： Janicki PK,Schuler HG,Jarzembowski TM,Rossi M 2nd

更新日期：2006-04-01 00:00:00

abstract：UNLABELLED:In this prospective investigation, we evaluated the efficacy and accuracy of transcutaneous monitoring of CO2 (TC-CO2) in infants and children after cardiothoracic surgery. Cardiothoracic surgery patients whose ETCO2 and arterial CO2 values did not correlate (gradient > or = 5 mm Hg) during the first postope...

journal_title：Anesthesia and analgesia

authors： Tobias JD,Wilson WR Jr,Meyer DJ

更新日期：1999-03-01 00:00:00

abstract：UNLABELLED:Propofol (Diprivan(TM); AstraZeneca, Wilmington, DE) is a commonly used drug for the induction of general anesthesia in the ambulatory setting. With the availability of a new bisulfite-containing generic formulation of propofol, questions have arisen regarding its cost effectiveness and safety compared with ...

journal_title：Anesthesia and analgesia

authors： Shao X,Li H,White PF,Klein KW,Kulstad C,Owens A

更新日期：2000-10-01 00:00:00

abstract：:Adrenomedullin is a potent vasodilatory peptide. Plasma adrenomedullin (AM) concentrations increase during and after cardiopulmonary bypass (CPB). However, the cause of this increase and its site of production have not been identified. We investigated the role of the hepatosplanchnic and cerebral circulations in the i...

journal_title：Anesthesia and analgesia

authors： Yoshikawa D,Kawahara F,Okano N,Hiraoka H,Kadoi Y,Fujita N,Morita T,Goto F

更新日期：2003-09-01 00:00:00

abstract：UNLABELLED:We investigated the possibility of using argon, an inert gas, as a replacement for carbon dioxide (CO2). The tolerance of argon pneumoperitoneum was compared with that of CO2 pneumoperitoneum. Twenty pigs were anesthetized with enflurane 1.5%. Argon (n = 11) or CO2 (n = 9) pneumoperitoneum was created at 15 ...

journal_title：Anesthesia and analgesia

authors： Mann C,Boccara G,Grevy V,Navarro F,Fabre JM,Colson P

更新日期：1997-12-01 00:00:00

abstract：:During Gram-negative sepsis, endotoxin lipopolysaccharide (LPS) may activate host inflammatory responses, resulting in the systemic inflammatory response syndrome and the adult respiratory distress syndrome. In cell culture systems, LPS activation of cellular responses may be potentiated by plasma proteins. In the iso...

journal_title：Anesthesia and analgesia

authors： Goldsmith JA,Kavanagh BP,Pearl RG

更新日期：1996-08-01 00:00:00

abstract：UNLABELLED:Although isoflurane can reduce ischemic neuronal injury after short postischemic recovery intervals, this neuroprotective efficacy is not sustained. Neuronal apoptosis can contribute to the gradual increase in infarct size after ischemia. This suggests that isoflurane, although capable of reducing early neur...

journal_title：Anesthesia and analgesia

authors： Kawaguchi M,Drummond JC,Cole DJ,Kelly PJ,Spurlock MP,Patel PM

更新日期：2004-03-01 00:00:00

abstract：UNLABELLED:The aim of this study was to examine the antiallodynic and antinociceptive effects of subcutaneously administered physostigmine (50, 100, 200 micrograms/kg), compared with morphine (2.5, 5, 10 mg/kg) and NaCl after spinal nerve ligation in rats. The following stimuli were used: acetone (cold allodynia), von ...

journal_title：Anesthesia and analgesia

authors： Pöyhiä R,Xu M,Kontinen VK,Paananen S,Kalso E

更新日期：1999-08-01 00:00:00

abstract：UNLABELLED:Propofol is a cardiac depressant with minimal diastolic effects in the adult myocardium. Cardiac effects of propofol in the newborn are unknown. We examined hemodynamic variables and systolic and diastolic left ventricular function in 12 newborn pigs exposed to propofol at three different infusion rates (7.5...

journal_title：Anesthesia and analgesia

authors： Graham MR,Thiessen DB,Mutch WA

更新日期：1998-04-01 00:00:00

abstract：UNLABELLED:Isoflurane reduces myocardial infarct size during early reperfusion by activating phosphatidylinositol-3-kinase (PI3K) signaling. We tested the hypothesis that this cardioprotection against reperfusion injury is enhanced by morphine and that a decrease in apoptosis plays a role in preservation of myocardial ...

journal_title：Anesthesia and analgesia

authors： Weihrauch D,Krolikowski JG,Bienengraeber M,Kersten JR,Warltier DC,Pagel PS

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Although music is frequently used to promote a relaxing environment during labor and delivery, the effect of its use during the placement of neuraxial techniques is unknown. Our study sought to determine the effects of music use on laboring parturients during epidural catheter placement, with the hypothesis ...

journal_title：Anesthesia and analgesia

authors： Drzymalski DM,Tsen LC,Palanisamy A,Zhou J,Huang CC,Kodali BS

更新日期：2017-02-01 00:00:00

abstract：:Combinations of alpha 2 agonists and opiates are used in the clinical management of pain to harness their potential synergistic interaction for analgesia while limiting their side-effects. To better predict the clinical consequences of this combination, we studied the behavioral effects of dexmedetomidine, a highly se...

journal_title：Anesthesia and analgesia

authors： Hayashi Y,Guo TZ,Maze M

更新日期：1996-09-01 00:00:00