Pharmacokinetics of thiopental and pentobarbital enantiomers after intravenous administration of racemic thiopental.

abstract：BACKGROUND:Current methods of information transfer in the operating room between monitor and anesthesiologist rely on visual and auditory modalities. These modalities can easily become overloaded in a high cognitive workload situation, such as in a critical incident. The use of vibrotactile communication has been shown...

journal_title：Anesthesia and analgesia

authors： Ford S,Daniels J,Lim J,Koval V,Dumont G,Schwarz SK,Ansermino JM

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Although music is frequently used to promote a relaxing environment during labor and delivery, the effect of its use during the placement of neuraxial techniques is unknown. Our study sought to determine the effects of music use on laboring parturients during epidural catheter placement, with the hypothesis ...

journal_title：Anesthesia and analgesia

authors： Drzymalski DM,Tsen LC,Palanisamy A,Zhou J,Huang CC,Kodali BS

更新日期：2017-02-01 00:00:00

abstract：:This randomized double-blind study compared the hemodynamic and metabolic effects of pancuronium and vecuronium during treatment of shivering after cardiac surgery with hypothermic cardiopulmonary bypass. Thirty sedated and pain-free patients who shivered after cardiac surgery were treated with pancuronium (n = 15) or...

journal_title：Anesthesia and analgesia

authors： Dupuis JY,Nathan HJ,DeLima L,Wynands JE,Russell GN,Bourke M

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:Recent attention to adverse effects of intensive care unit (ICU) sedation has led to the use of strategies that target a "lighter" depth of sedation. Among these strategies are "analgosedation" protocols, which prioritize pain management and preferentially use IV opioids before administration of continuously...

journal_title：Anesthesia and analgesia

authors： Faust AC,Rajan P,Sheperd LA,Alvarez CA,McCorstin P,Doebele RL

更新日期：2016-10-01 00:00:00

abstract：:A 62-yr-old man presented for a microdirect laryngoscopy and vocal cord fat grafting under jet ventilation. After a prolonged laryngoscopy, the patient developed hypercapnea and upper airway obstruction secondary to traumatic epiglottitis. The placement of a laryngeal mask airway provided ventilation and allowed for d...

journal_title：Anesthesia and analgesia

authors： Kidani DC,Shah NK

更新日期：2007-12-01 00:00:00

abstract：:We evaluated risk of heart block after cardiopulmonary by-pass (CPB) in patients with normal conduction undergoing coronary artery bypass grafting who chronically received calcium-entry blockers, beta-blockers, or combined therapy. Before CPB, calcium-entry blockers alone produced an increase in P-R intervals but no c...

journal_title：Anesthesia and analgesia

authors： Henling CE,Slogoff S,Kodali SV,Arlund C

更新日期：1984-05-01 00:00:00

abstract：BACKGROUND:The effect of neither transfusion guidelines nor decision support tools on intraoperative transfusion has been previously evaluated. The University of Michigan introduced a transfusion guideline in 2009, and in 2011, the Department of Anesthesiology developed a transfusion decision support tool. The primary ...

journal_title：Anesthesia and analgesia

authors： Picton P,Starr J,Kheterpal S,Thompson AML,Housey M,Sathishkumar S,Dubovoy T,Kirkpatrick N,Tremper KK,Engoren M,Ramachandran SK

更新日期：2018-09-01 00:00:00

abstract：:Early tracheal extubation has been safely performed after large operative procedures, questioning the need for routine postoperative ventilation. Because immediate postoperative tracheal extubation of liver transplantation patients has not been previously reported, we performed preliminary studies at two institutions ...

journal_title：Anesthesia and analgesia

authors： Mandell MS,Lockrem J,Kelley SD

更新日期：1997-02-01 00:00:00

abstract：:Previous studies have suggested that shocks of 5-10 J are required for direct ventricular defibrillation during open heart surgery. However, the efficacy of shocks of less than 5 J, the effects of thermal, biochemical, and temporal factors, and the influence of disease process on defibrillation have not been fully inv...

journal_title：Anesthesia and analgesia

authors： Lake CL,Sellers TD,Nolan SP,Crosby IK,Wellons HA Jr,Crampton RS

更新日期：1984-08-01 00:00:00

abstract：BACKGROUND:Pulmonary hypertension and resulting right ventricular (RV) dysfunction are associated with significant perioperative morbidity and mortality. Although echocardiography permits real-time, noninvasive assessment of RV function, objective and comparative measures are underdeveloped, and appropriate animal mode...

journal_title：Anesthesia and analgesia

authors： Bartels K,Brown RD,Fox DL,Bull TM,Neary JM,Dorosz JL,Fonseca BM,Stenmark KR

更新日期：2016-05-01 00:00:00

abstract：:Spontaneous ventilation may offer advantages over controlled mechanical ventilation (CMV), but increase in work of breathing may diminish its usefulness. During general anesthesia, respiratory depression and increased work of breathing often preclude spontaneous ventilation, and patients then receive CMV. We compared ...

journal_title：Anesthesia and analgesia

authors： Christie JM,Smith RA

更新日期：1992-08-01 00:00:00

abstract：:Fentanyl pharmacokinetics was compared in two groups of adult patients, one group (n = 5) aged less than 50 years, and one group (n = 4) aged greater than 60 years. Despite equivalent doses of fentanyl (10 microgram/kg IV), serum drug concentrations were significantly higher in the older patient group. This was reflec...

journal_title：Anesthesia and analgesia

authors： Bentley JB,Borel JD,Nenad RE Jr,Gillespie TJ

更新日期：1982-12-01 00:00:00

abstract：:In vitro experiments using guinea pig tracheal smooth muscle were performed to compare the relaxant properties of procaine, lidocaine, and ketamine following contracture induced by histamine. Procaine produced a spasmolytic effect in a dose-related manner. In the doses tested, relaxation induced by procaine was more p...

journal_title：Anesthesia and analgesia

authors： Wanna HT,Gergis SD

更新日期：1978-01-01 00:00:00

abstract：:The effect of age (over 70 yr) on the pharmacokinetics and pharmacodynamics of edrophonium was evaluated in seven patients aged 76-87 yr and in seven patients aged 27-57 yr. When elderly patients were compared with younger controls, the elderly exhibited a statistically significant decreased plasma clearance (5.9 +/- ...

journal_title：Anesthesia and analgesia

authors： Matteo RS,Young WL,Ornstein E,Schwartz AE,Silverberg PA,Diaz J

更新日期：1990-10-01 00:00:00

abstract：:Studies were conducted on the effects of isoflurane and halothane on intracellular mechanisms of striated muscle contraction: Ca2+ activation of the contractile proteins and Ca2+ uptake and release from the sarcoplasmic reticulum. Functionally skinned muscle fibers (sarcolemma disrupted by homogenization) from isolate...

journal_title：Anesthesia and analgesia

authors： Su JY,Bell JG

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND:Mounting evidence from animal studies shows that anesthetic exposure in early life leads to apoptosis in the developing nervous system. This loss of neurons has functional consequences in adulthood. Clinical retrospective reviews have suggested that multiple anesthetic exposures in early childhood are associ...

journal_title：Anesthesia and analgesia

authors： Gentry KR,Steele LM,Sedensky MM,Morgan PG

更新日期：2013-01-01 00:00:00

abstract：:We studied the possible effects of repetitive (1-min interval) 50- and 100-Hz tetanic stimuli on 50-Hz and 100-Hz tetanic fade ratios (RF50HZ and RF100HZ). We also evaluated the sensitivity of the recorded responses to these two tests to assess residual neuromuscular block (isometric adductor pollicis mechanical activ...

journal_title：Anesthesia and analgesia

authors： Baurain MJ,Hoton F,Dernovoi BS,d'Hollander AA

更新日期：1996-01-01 00:00:00

abstract：:Cardiopulmonary bypass (CPB) impairs pulmonary endothelial injury in part by increasing expression of adhesion molecules that results in neutrophil influx. Although numerous proinflammatory cytokines up-regulate these responses, the extent to which systemic and pulmonary proinflammatory cytokines increase remains unkn...

journal_title：Anesthesia and analgesia

authors： Kotani N,Hashimoto H,Sessler DI,Muraoka M,Wang JS,O'Connor MF,Matsuki A

更新日期：2000-05-01 00:00:00

abstract：UNLABELLED:We examined the effect of ulinastatin, a protease inhibitor purified from human urine, on neuromuscular block caused by vecuronium. Sixty adult patients were randomly divided into four groups of 15 patients each: ulinastatin-posttetanic count (U-PTC), ulinastatin-train-of-four (U-TOF), control-posttetanic co...

journal_title：Anesthesia and analgesia

authors： Saitoh Y,Fujii Y,Oshima T

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:The recommended treatment of suspected tension pneumothorax is immediate needle decompression. Recommended sites and needle sizes for this procedure vary, and there are published reports of failed decompression as well as iatrogenic hemothorax. We investigated the optimal needle length and relative safety of...

journal_title：Anesthesia and analgesia

authors： Wax DB,Leibowitz AB

更新日期：2007-11-01 00:00:00

abstract：UNLABELLED:Inhaled nitric oxide (iNO) is superior to i.v. vasodilators for treatment of pulmonary hypertension (PH) after cardiac surgery, but iNO is a potentially toxic gas, and patient subsets who benefit from iNO are not yet clearly defined. We administered iNO 40 ppm, prostaglandin E1 (PGE1) 0.1 microg x kg(-1) min...

journal_title：Anesthesia and analgesia

authors： Schmid ER,Bürki C,Engel MH,Schmidlin D,Tornic M,Seifert B

更新日期：1999-11-01 00:00:00

abstract：:Patients receiving metoprolol before cardiac revascularization surgery were randomly divided into those in whom metoprolol was discontinued before the operation (N = 10) and those in whom metoprolol was continued up to the time of operation (N = 10). Cardiovascular responses to neuroleptanesthesia and sternotomy were ...

journal_title：Anesthesia and analgesia

authors： Pontén J,Häggendal J,Milocco I,Waldenström A

更新日期：1983-04-01 00:00:00

abstract：:To determine the incidence of atrioventricular (A-V) block, 86 patients, aged 58.9 +/- 10.4 yr, undergoing elective coronary artery bypass grafting (CABG) during aortic cross-clamping (ACC) and cold potassium cardioplegia were investigated. The incidence and duration of complete A-V block after release of the aortic c...

journal_title：Anesthesia and analgesia

authors： Baraka AS,Taha SK,Yazbeck VK,Rizkallah PA,Zughbi JP,Aouad MJ,Rouhana CS,Nader AM

更新日期：1995-01-01 00:00:00

abstract：:Quantitative electroencephalogram (qEEG) monitors are often used to estimate depth of anesthesia and intraoperative recall during general anesthesia. As with any monitor, the processed numerical output is often misleading and has to be interpreted within a clinical context. For the safe clinical use of these monitors,...

journal_title：Anesthesia and analgesia

authors： Bennett C,Voss LJ,Barnard JP,Sleigh JW

更新日期：2009-08-01 00:00:00

abstract：UNLABELLED:Clonidine decreases the stress-induced sympathoadrenal responses to painful stimuli and improves hemodynamic stability during general anesthesia. Because acute hypertensive responses are often observed immediately after electroconvulsive therapy (ECT), we designed a prospective, randomized, placebo-controlle...

journal_title：Anesthesia and analgesia

authors： Fu W,Stool LA,White PF,Husain MM

更新日期：1998-05-01 00:00:00

abstract：:Several studies have investigated differential block during spinal anesthesia using transcutaneous electrical stimulation (TES) applied to patient's skin. These TES stimuli are claimed to be a surrogate for surgical stimulation, but TES has never been shown to be a realistic surrogate for a surgical stimulus during re...

journal_title：Anesthesia and analgesia

authors： Zaidi AS,Russell IF

更新日期：2005-05-01 00:00:00

abstract：:Ondansetron and droperidol are both effective in the prevention of postoperative nausea and vomiting (PONV). In this randomized, double-blind study, 80 inpatients scheduled for minor gynecologic surgery received either ondansetron 8 mg intravenously (i.v.) or droperidol 2.5 mg i.v. 5 min prior to induction of isoflura...

journal_title：Anesthesia and analgesia

authors： Grond S,Lynch J,Diefenbach C,Altrock K,Lehmann KA

更新日期：1995-09-01 00:00:00

abstract：:Fluid resuscitation is one of the most prevalent treatment in critical care. There is not definitive evidence about the best fluid for resuscitation. The aim of this review will be to asses the efficacy and safety of buffered solution versus saline. We will perform an electronic search in Medline, Embase, and Central....

journal_title：Anesthesia and analgesia

authors： Barea-Mendoza JA,Antequera AM,Plana MN,Chico-Fernández M,Muriel A,Sáez I,Estrada-Lorenzo JM,Montejo-González JC

更新日期：2016-12-01 00:00:00

abstract：UNLABELLED:Nitrous oxide (N(2)O) exerts a sympathomimetic action. We investigated whether N(2)O modifies the cardiovascular responses to tracheal intubation during general anesthesia. One-hundred healthy patients were assigned randomly to receive one of four concentrations (0%, 25%, 50%, or 75%; n = 25 each) of N(2)O i...

journal_title：Anesthesia and analgesia

authors： Yoo KY,Jeong ST,Ha IH,Lee J

更新日期：2003-05-01 00:00:00

abstract：:Although clonidine has been shown to increase the duration of local anesthetic action and prolong postoperative analgesia when included in single-injection nerve blocks, the only controlled investigation of the efficacy of this practice to improve analgesia for continuous perineural local anesthetic infusion failed to...

journal_title：Anesthesia and analgesia

authors： Ilfeld BM,Morey TE,Thannikary LJ,Wright TW,Enneking FK

更新日期：2005-04-01 00:00:00