Randomized safety studies of intravenous perflubron emulsion. I. Effects on coagulation function in healthy volunteers.

abstract：:This study examined global hemodynamic responses to increasing concentrations of halothane and isoflurane in pigs with an acute critical coronary stenosis (CCS) on the left anterior descending coronary artery (LAD). The CCS was caused by graded inflation of an hydraulic occluder to the point where no hyperemic respons...

journal_title：Anesthesia and analgesia

authors： Gilbert M,Mori M,Myhre ES

更新日期：1989-06-01 00:00:00

abstract：:One-hundred and eight-five pairs of gas samples were collected from inspired gas (10 cm behind the head at nose level) and end-tidal gas of persons administering anesthesia in 3 operating rooms during daily routine anesthesia. Mean operating-room N2O concentrations from 22 to 144 ppm (volume/volume [V/V]) were measure...

journal_title：Anesthesia and analgesia

authors： Beynen FM,Knopp TJ,Rehder K

更新日期：1978-03-01 00:00:00

abstract：BACKGROUND:The effect of interscalene block (ISB) on pulmonary function of obese participants has not been investigated. The goal of this study is to assess the association of obesity (body mass index [BMI] >29 kg/m vs BMI <25 kg/m) and change in forced vital capacity (FVC) and forced expiratory volume in 1 second (FEV...

journal_title：Anesthesia and analgesia

authors： Melton MS,Monroe HE,Qi W,Lewis SL,Nielsen KC,Klein SM

更新日期：2017-07-01 00:00:00

abstract：UNLABELLED:Postanesthetic shivering can be treated with many types of drugs. We compared the effects of meperidine, clonidine, and urapidil on postanesthetic shivering. Sixty patients shivering during recovery from general anesthesia were treated in a randomized, double-blinded fashion with 25 mg meperidine IV, 0.15 mg...

journal_title：Anesthesia and analgesia

authors： Schwarzkopf KR,Hoff H,Hartmann M,Fritz HG

更新日期：2001-01-01 00:00:00

abstract：:The cold pressor test is often used to assess vasoconstrictive responses because it simulates the vasoconstrictive challenges commonly encountered in the clinical setting. With IRB approval, 12 healthy volunteers, aged 25--50 yr, underwent baseline plethysmographic monitoring on the finger and ear. The contralateral h...

journal_title：Anesthesia and analgesia

authors： Awad AA,Ghobashy MA,Ouda W,Stout RG,Silverman DG,Shelley KH

更新日期：2001-06-01 00:00:00

abstract：UNLABELLED:Dichloroacetate (DCA) stimulates pyruvate dehydrogenase (PDH), accelerating recovery of the postischemic heart. Because DCA also stimulates hepatic PDH, it may facilitate graft recovery during liver transplantation (OLT). Hepatic removal and replacement during OLT produce major changes in O2 consumption (VO2...

journal_title：Anesthesia and analgesia

authors： Shangraw RE,Robinson ST

更新日期：1997-10-01 00:00:00

abstract：:Cardioprotection by anesthetic preconditioning (APC) can be abolished by nitric oxide (NO*) synthase inhibitors or by reactive oxygen species (ROS) scavengers. We previously reported attenuated mitochondrial electron transport (ET) and increased ROS generation during preconditioning sevoflurane exposure as part of the...

journal_title：Anesthesia and analgesia

authors： Riess ML,Kevin LG,McCormick J,Jiang MT,Rhodes SS,Stowe DF

更新日期：2005-01-01 00:00:00

abstract：:A 6-year experience in the anesthetic management of 34 successful whole-lung lavages on 11 adult patients with pulmonary alveolar proteinosis is described. All patients were radiographically, physiologically, and symptomatically improved after the procedures. The anesthetic protocol for lung lavage includes: (1) unila...

journal_title：Anesthesia and analgesia

authors： Lippmann M,Mok MS

更新日期：1977-09-01 00:00:00

abstract：:We studied 60 nonophthalmologic patients, allocated to six treatment groups, to assess the effects of atracurium and vecuronium on intraocular pressure (IOP). All patients had IOP measured while awake, using pneumotonometry. In group 1, anesthesia was induced with thiopental, 5 mg/kg, and maintained with N2O, 70% in O...

journal_title：Anesthesia and analgesia

authors： Schneider MJ,Stirt JA,Finholt DA

更新日期：1986-08-01 00:00:00

abstract：UNLABELLED:Nasotracheal intubation is often required during dental and maxillofacial surgery. The complications of nasotracheal intubation are well documented, but there have been few systematic attempts to find methods for their prevention. We examined intubation-related carriage of bacteria, especially methicillin-re...

journal_title：Anesthesia and analgesia

authors： Takahashi S,Minami K,Ogawa M,Miyamoto H,Ikemura K,Shigematsu A,Taniguchi H

更新日期：2003-07-01 00:00:00

abstract：:The efficacy of lidocaine during myocardial reperfusion in coronary artery bypass surgery was evaluated in 20 patients randomly assigned to a control group (n = 10) or to receive lidocaine, 1 mg/kg intravenously 5 min before aortic unclamping and cardiac reperfusion, followed by infusion at 40 micrograms X kg-1 X min-...

journal_title：Anesthesia and analgesia

authors： Lake CL,Kron IL,Mentzer RM,Crampton RS

更新日期：1986-04-01 00:00:00

abstract：:The pharmacokinetics of lidocaine were studied in nonpregnant and pregnant ewes. The maternal femoral vessels were cannulated and, on the day of study, the urinary bladder was catheterized. Lidocaine HCl, 4-5 mg/kg, was administered by IV injection over 60 seconds. Serial samples of arterial blood and urine were colle...

journal_title：Anesthesia and analgesia

authors： Santos AC,Pedersen H,Morishima HO,Finster M,Arthur GR,Covino BG

更新日期：1988-12-01 00:00:00

abstract：:This study was designed to determine whether preoperative administration of 6% hetastarch decreases the incidence and severity of hypotension after spinal anesthesia for cesarean section. Forty nonlaboring ASA class I and II women having nonurgent cesarean sections were randomized to receive either 500 mL of 6% hetast...

journal_title：Anesthesia and analgesia

authors： Riley ET,Cohen SE,Rubenstein AJ,Flanagan B

更新日期：1995-10-01 00:00:00

abstract：:An in vitro model was used to determine the force required to pierce bovine dura with a range of new spinal needles and to measure the subsequent leakage rate of cerebrospinal fluid (CSF). A significantly greater force was required to pierce the dura with pencil-point style needles compared to Quincke needles of the s...

journal_title：Anesthesia and analgesia

authors： Westbrook JL,Uncles DR,Sitzman BT,Carrie LE

更新日期：1994-10-01 00:00:00

abstract：:Elevated serum ammonia may play a role in central nervous system derangement after transurethral resection of the prostate. Glycine used as a surgical irrigant for prostate resection produces ammonia as a by-product after liver and renal metabolism. The presence of liver dysfunction often leads to an inability to remo...

journal_title：Anesthesia and analgesia

authors： Frink EJ Jr,DiGiovanni DA,Davis JR,Brown BR Jr

更新日期：1989-12-01 00:00:00

abstract：BACKGROUND:The perioperative assessment of right ventricular (RV) function remains a challenge. Tricuspid annular plane systolic excursion (TAPSE) using M-mode is a widely used measure of RV function. However, accurate alignment of the ultrasound beam with the direction of annular movement can be difficult with transes...

journal_title：Anesthesia and analgesia

authors： Shen T,Picard MH,Hua L,Burns SM,Andrawes MN

更新日期：2018-01-01 00:00:00

abstract：UNLABELLED:A cohort of seven patients receiving intrathecal analgesic drug therapy for chronic intractable pain underwent radiocontrast myelography and computed tomography (CT) scanning to screen for catheter-associated intrathecal masses. Three of seven patients examined had intraspinal masses associated with the tip ...

journal_title：Anesthesia and analgesia

authors： McMillan MR,Doud T,Nugent W

更新日期：2003-01-01 00:00:00

abstract：UNLABELLED:Adhesion of polymorphonuclear neutrophils (PMN) to the coronary endothelium is a crucial step in the development of ischemic myocardial injury. We tested the possible effects of six widely used IV anesthetics on non- and postischemic coronary adhesion of PMN in isolated perfused guinea pig hearts. Hearts (n ...

journal_title：Anesthesia and analgesia

authors： Szekely A,Heindl B,Zahler S,Conzen PF,Becker BF

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:Pediatric chronic pain is very common and results in significant health care costs. Pediatric chronic pain is both an individual and a public health concern. The primary objective of this study was to generate a descriptive clinical profile of the patients referred to an anesthesiology-based pediatric chroni...

journal_title：Anesthesia and analgesia

authors： Vetter TR

更新日期：2008-03-01 00:00:00

abstract：:The acute central nervous and cardiovascular effects of the local anesthetics ropivacaine and bupivacaine were compared in 12 volunteers in a randomized double-blind manner with use of intravenous infusions at a rate of 10 mg/min up to a maximal dose of 150 mg. The volunteers were all healthy men. They were familiariz...

journal_title：Anesthesia and analgesia

authors： Scott DB,Lee A,Fagan D,Bowler GM,Bloomfield P,Lundh R

更新日期：1989-11-01 00:00:00

abstract：:Complement activation and the resulting inflammatory response is an important potential mechanism for multisystem organ injury in cardiac surgery. Novel therapeutic strategies using complement inhibitors may hold promise for improving outcomes for cardiac surgical patients by attenuating complement activation or its b...

journal_title：Anesthesia and analgesia

authors： Stahl GL,Shernan SK,Smith PK,Levy JH

更新日期：2012-10-01 00:00:00

abstract：UNLABELLED:The purpose of this study was to determine if rates of telemetry events differ between patients whose monitoring is appropriately "indicated" versus "not indicated" by systematically applying rigorous criteria for appropriateness of electrocardiogram (ECG) telemetry usage. We performed a retrospective cohort...

journal_title：Anesthesia and analgesia

authors： Curry JP,Hanson CW 3rd,Russell MW,Hanna C,Devine G,Ochroch EA

更新日期：2003-11-01 00:00:00

abstract：UNLABELLED:Adenosine and adenosine analogs induce analgesia in humans and presumed antinociception in animal models when administered both systemically and intrathecally. In the present investigation in rats, we studied the effects of intrathecally administered adenosine analogs, with or without systemic coadministrati...

journal_title：Anesthesia and analgesia

authors： Sjölund KF,Sollevi A,Segerdahl M,Lundeberg T

更新日期：1997-09-01 00:00:00

abstract：:We measured arterial plasma concentrations of lidocaine by enzyme immunoassay when 10 ml of 2% lidocaine without epinephrine was injected into the cervical, thoracic, or lumbar epidural spaces in 30 patients. There was no difference in the time courses of plasma levels of lidocaine. Peak concentrations were achieved 1...

journal_title：Anesthesia and analgesia

authors： Mayumi T,Dohi S,Takahashi T

更新日期：1983-06-01 00:00:00

abstract：UNLABELLED:Although the importance of the nucleus raphe magnus in descending inhibitory control of nociception is clear, it is not known whether these effects are equivalent for different types of nociception. Thus, we examined the differential inhibition of behavioral responses evoked by A delta or C fiber thermonocic...

journal_title：Anesthesia and analgesia

authors： Lu Y,Sweitzer SM,Laurito CE,Yeomans DC

更新日期：2004-02-01 00:00:00

abstract：:To quantify the effects of succinylcholine at the laryngeal adductor muscles and the adductor pollicis, 17 adult patients were studied during propofol-fentanyl anesthesia. Train-of-four stimulation was applied to the ulnar nerve at the wrist and the recurrent laryngeal nerve at the notch of the thyroid cartilage. Lary...

journal_title：Anesthesia and analgesia

authors： Meistelman C,Plaud B,Donati F

更新日期：1991-09-01 00:00:00

abstract：UNLABELLED:Animal studies have suggested that the temporal summation of nociceptive inputs might play a significant role in the development of central sensitization (i.e., hyperexcitability of central nociceptive neurons) and hyperalgesia via the activation of N-methyl-D-aspartate receptors. To further analyze these pr...

journal_title：Anesthesia and analgesia

authors： Guirimand F,Dupont X,Brasseur L,Chauvin M,Bouhassira D

更新日期：2000-02-01 00:00:00

abstract：:Many inhaled anesthetics and intravenous analgesics have been alleged to produce both proconvulsant and anticonvulsant activity in humans. The reasons for these contrasting actions on the CNS are poorly understood at the present time. However, biologic variability plays an important role in determining individual pati...

journal_title：Anesthesia and analgesia

authors： Modica PA,Tempelhoff R,White PF

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:Postpartum depression (PPD) is associated with pain during and after delivery, with studies showing reduced rates among women delivering with labor epidural analgesia (LEA). We hypothesized that women who intend to deliver with LEA but do not receive it are at higher risk for PPD at 6 weeks due to the combin...

journal_title：Anesthesia and analgesia

authors： Orbach-Zinger S,Landau R,Harousch AB,Ovad O,Caspi L,Kornilov E,Ioscovich A,Bracco D,Davis A,Fireman S,Hoshen M,Eidelman LA

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:The clinical utility of focused transthoracic echocardiography (TTE) is increasingly recognized in perioperative medicine. However its use is limited among anesthesiologists because of a lack of training. The most efficient training methods have not been determined. We hypothesized that simulation-based TTE ...

journal_title：Anesthesia and analgesia

authors： Neelankavil J,Howard-Quijano K,Hsieh TC,Ramsingh D,Scovotti JC,Chua JH,Ho JK,Mahajan A

更新日期：2012-11-01 00:00:00