Pro- and anticonvulsant effects of anesthetics (Part I)

abstract：UNLABELLED:A 3-yr-old with B-cell lymphoma presented with a 5-wk history of 400 mL/day cerebrospinal fluid (CSF) leak, which precluded chemotherapy, after placement of an Omaya reservoir and drain. Surgical repair was unsuccessful. Symptoms included irritability, failure to eat and noncommunication. After lumbar epidur...

journal_title：Anesthesia and analgesia

authors： Sanders JC,Gandhoke R,Moro M

更新日期：2004-03-01 00:00:00

abstract：:The purpose of this study was to examine the effects of dexmedetomidine, an alpha 2-adrenergic agonist, on cerebral blood flow and metabolic rate in dogs anesthetized with 0.64% isoflurane. After intubation and institution of mechanical ventilation, arterial, venous, pulmonary artery, and sagittal sinus catheters were...

journal_title：Anesthesia and analgesia

authors： Zornow MH,Fleischer JE,Scheller MS,Nakakimura K,Drummond JC

更新日期：1990-06-01 00:00:00

abstract：UNLABELLED:We compared the laryngeal mask airway ProSeal (PLMA) and the laryngeal tube airway (LTA), two new extraglottic airway devices, with respect to: 1) insertion success rates and times, 2) efficacy of seal, 3) ventilatory variables during pressure-controlled ventilation, 4) tidal volume in different head/neck po...

journal_title：Anesthesia and analgesia

authors： Brimacombe J,Keller C,Brimacombe L

更新日期：2002-09-01 00:00:00

abstract：UNLABELLED:Clinical pathways are being introduced by hospitals to reduce costs and control unnecessary variation in care. We studied 766 inpatients to measure the impact of a perioperative clinical pathway for patients undergoing knee replacement surgery on hospital costs. One hundred twenty patients underwent knee rep...

journal_title：Anesthesia and analgesia

authors： Macario A,Horne M,Goodman S,Vitez T,Dexter F,Heinen R,Brown B

更新日期：1998-05-01 00:00:00

abstract：:Common practice during local anesthetic injection is to warn the patient using words such as: "You will feel a big bee sting; this is the worst part." Our hypothesis was that using gentler words for administration of the local anesthetic improves pain perception and patient comfort. One hundred forty healthy women at ...

journal_title：Anesthesia and analgesia

authors： Varelmann D,Pancaro C,Cappiello EC,Camann WR

更新日期：2010-03-01 00:00:00

abstract：UNLABELLED:We evaluated the effects of aggressive warming and maintenance of normothermia on surgical blood loss and allogeneic transfusion requirement. We randomly assigned 150 patients undergoing total hip arthroplasty with spinal anesthesia to aggressive warming (to maintain a tympanic membrane temperature of 36.5 d...

journal_title：Anesthesia and analgesia

authors： Winkler M,Akça O,Birkenberg B,Hetz H,Scheck T,Arkiliç CF,Kabon B,Marker E,Grübl A,Czepan R,Greher M,Goll V,Gottsauner-Wolf F,Kurz A,Sessler DI

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:Lidocaine can alleviate acute as well as chronic neuropathic pain at very low plasma concentrations in humans and laboratory animals. The mechanism(s) underlying lidocaine's analgesic effect when administered systemically is poorly understood but clearly not related to interruption of peripheral nerve conduc...

journal_title：Anesthesia and analgesia

authors： Luo Z,Yu M,Smith SD,Kritzer M,Du C,Ma Y,Volkow ND,Glass PS,Benveniste H

更新日期：2009-01-01 00:00:00

abstract：UNLABELLED:Previous investigations of the effects of potent opioid analgesics on the heart have concentrated on effects on contraction magnitude and time course, but little is known about their effects on cytosolic Ca(2+) regulation in cardiac tissue. In this study, we sought to assess the effects of alfentanil on cont...

journal_title：Anesthesia and analgesia

authors： Graham MD,Hopkins PM,Harrison SM

更新日期：2004-04-01 00:00:00

abstract：UNLABELLED:In a 28-mo period 14 multiple-casualty terror events occurred in Jerusalem, challenging the Department of Anesthesiology and Critical Care Medicine of the city's sole Level 1 trauma center. We performed a retrospective review of the response of the department to evaluate staff activities, resource use (emerg...

journal_title：Anesthesia and analgesia

authors： Shamir MY,Weiss YG,Willner D,Mintz Y,Bloom AI,Weiss Y,Sprung CL,Weissman C

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:We evaluated in which anatomic layer (above the fascia [AF] or below the fascia [BF]) wound infusion of bupivacaine has the best effect on postoperative pain after abdominal hysterectomy. METHODS:Sixty-two ASA physical status I and II patients undergoing total abdominal hysterectomy and bilateral salpingo-o...

journal_title：Anesthesia and analgesia

authors： Hafizoglu MC,Katircioglu K,Ozkalkanli MY,Savaci S

更新日期：2008-12-01 00:00:00

abstract：:This study evaluates the changes of oxygen saturation (SpO2) after intravenous administration of methylene blue in 103 patients undergoing open repair of thoracoabdominal aortic aneurysms. We found that SpO2 decreased by a median (interquartile range [IQR]) of 49% (37%-81%) <1 minute after methylene blue administratio...

journal_title：Anesthesia and analgesia

authors： Rong LQ,Mauer E,Mustapich TL,White RS,Di Franco A,Girardi LN,Gaudino M,Pryor KO

更新日期：2019-11-01 00:00:00

abstract：:In in vitro pharmacological experiments, determination of effective concentration values for various anesthetics depends on understanding the exact concentration of the drugs dissolved in physiological solutions. Actual anesthetic concentration may differ from expectations because of drug adsorption, absorption or oth...

journal_title：Anesthesia and analgesia

authors： Suzuki T,Uchida I,Mashimo T

更新日期：2005-02-01 00:00:00

abstract：UNLABELLED:In this study, we tested the validity of the bispectral index (BIS) monitor during conscious and deep sedation of children by comparing it with the University of Michigan Sedation Scale (UMSS), a validated observational pediatric sedation scale. Eighty-six children <12 yr of age were enrolled in this observa...

journal_title：Anesthesia and analgesia

authors： McDermott NB,VanSickle T,Motas D,Friesen RH

更新日期：2003-07-01 00:00:00

abstract：:Previous studies have suggested that shocks of 5-10 J are required for direct ventricular defibrillation during open heart surgery. However, the efficacy of shocks of less than 5 J, the effects of thermal, biochemical, and temporal factors, and the influence of disease process on defibrillation have not been fully inv...

journal_title：Anesthesia and analgesia

authors： Lake CL,Sellers TD,Nolan SP,Crosby IK,Wellons HA Jr,Crampton RS

更新日期：1984-08-01 00:00:00

abstract：:A study was undertaken in 15 patients to compare measured and assumed arteriovenous oxygen (A-V O2) content differences and their effects on resultant shunt calculations. All patients were on volume ventilators and demonstrated a stable cardiovascular state. Simultaneous measurements of the O2 content of a pulmonary a...

journal_title：Anesthesia and analgesia

authors： Harrison RA,Davison R,Shapiro BA,Meyers SN

更新日期：1975-03-01 00:00:00

abstract：:The effect of enflurane anesthesia on bronchomotor tone was studied in 15 dogs, using isolated tracheal segments in situ. In six animals, the changes of tracheal tension in response to changing enflurane concentration were continuously measured while keeping tidal volume, respiratory frequency, and end-tidal PCO2 cons...

journal_title：Anesthesia and analgesia

authors： Kochi T,Hagiya M,Mizuguchi T

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:In this study we sought to determine whether the topographical measurement along the course of the central veins can estimate the approximate insertion depths of central venous catheters (CVC). METHODS:Two hundred central venous catheterizations were performed via the right and left internal jugular vein (I...

journal_title：Anesthesia and analgesia

authors： Kim MC,Kim KS,Choi YK,Kim DS,Kwon MI,Sung JK,Moon JY,Kang JM

更新日期：2011-06-01 00:00:00

abstract：:The sensitivity, specificity, and accuracy of the cobalt blue and ninhydrin sweat tests were compared with the sympathogalvanic response (SGR) in assessment of complete sympathetic blockade. Patients were randomly assigned to receive epidural administration of either preservative-free physiologic saline solution and 8...

journal_title：Anesthesia and analgesia

authors： Benzon HT,Cheng SC,Avram MJ,Molloy RE

更新日期：1985-04-01 00:00:00

abstract：UNLABELLED:Tropisetron is a 5-hydroxytryptamine subtype 3 receptor antagonist that is primarily used in the prevention of chemotherapy-induced nausea and vomiting. We evaluated the prophylactic effect of tropisetron on postoperative nausea and vomiting associated with epidural morphine. Dexamethasone and saline served ...

journal_title：Anesthesia and analgesia

authors： Wang JJ,Tzeng JI,Ho ST,Chen JY,Chu CC,So EC

更新日期：2002-03-01 00:00:00

abstract：:Continuous peripheral nerve blockade is often used for the management of postoperative pain, even in ambulatory patients. The reported incidence of infectious complications after continuous nerve blockade is low. We report a case of Staphylococcus aureus sepsis after total shoulder arthroplasty in a patient who presen...

journal_title：Anesthesia and analgesia

authors： Clendenen SR,Robards CB,Wang RD,Greengrass RA

更新日期：2010-04-01 00:00:00

abstract：:Morphine plasma concentrations were determined in six patients receiving kidney transplants from living-related donors, and nine patients receiving kidney transplants from cadavers. The total cold ischemic time was about 2 hr for kidneys from living-related donors and 14 hr for those from cadavers. After an intravenou...

journal_title：Anesthesia and analgesia

authors： Sear J,Moore A,Hunniset A,Baldwin D,Allen M,Hand C,McQuay H,Morris P

更新日期：1985-11-01 00:00:00

abstract：UNLABELLED:We describe a case of type-2 diabetes mellitus with significant improvement in blood glucose control and significant decrease in insulin requirements after initiation of spinal cord stimulation. We believe that spinal cord stimulation may provide additional beneficial effects in patients with chronic pain an...

journal_title：Anesthesia and analgesia

authors： Kapural L,Hayek SM,Stanton-Hicks M,Mekhail N

更新日期：2004-03-01 00:00:00

abstract：:Spine surgery has been growing rapidly as a neurosurgical operation, with an increase of 220% over a 15-year period. Intraoperative blood transfusion is a major outcome determinant of spine procedures. Various approaches, including pharmacologic and nonpharmacologic therapies, have been tested to decrease both intraop...

journal_title：Anesthesia and analgesia

authors： Willner D,Spennati V,Stohl S,Tosti G,Aloisio S,Bilotta F

更新日期：2016-11-01 00:00:00

abstract：:The objective of this study was to compare the success of resuscitation attempts with different cardioactive drugs after bupivacaine-induced asystole. Saline, amrinone (1 mg/kg), dopamine (5 micrograms/kg), norepinephrine (2 micrograms/kg), epinephrine (10 micrograms/kg), or isoproterenol (1 microgram/kg) were tested....

journal_title：Anesthesia and analgesia

authors： Heavner JE,Pitkänen MT,Shi B,Rosenberg PH

更新日期：1995-06-01 00:00:00

abstract：BACKGROUND:Hypothermia may be accidental or therapeutic. Therapeutic hypothermia is increasingly used as treatment for various conditions, e.g., neuroprotection after cardiac arrest. Hypothermia leads to an impairment of the coagulation system, but the degree of impairment has been difficult to determine. Most studies ...

journal_title：Anesthesia and analgesia

authors： Rundgren M,Engström M

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:We hypothesized that, compared to remifentanil, dexmedetomidine used for endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) performed under monitored anesthesia care (MAC) in nonintubated patients would result in fewer episodes of major respiratory adverse events (number of episodes...

journal_title：Anesthesia and analgesia

authors： St-Pierre P,Tanoubi I,Verdonck O,Fortier LP,Richebé P,Côté I,Loubert C,Drolet P

更新日期：2019-01-01 00:00:00

abstract：:The hemodynamic effects of an induction dose of propofol, 2.5 mg/kg, or etomidate, 0.3 mg/kg, were studied in eight dogs. In addition, cardiodynamic changes were measured using a left ventricular catheter and needle force probes. Propofol was associated with significant decreases in systolic (19.9%) and diastolic (25....

journal_title：Anesthesia and analgesia

authors： Brüssel T,Theissen JL,Vigfusson G,Lunkenheimer PP,Van Aken H,Lawin P

更新日期：1989-07-01 00:00:00

abstract：:We used laser-Doppler flowmetry to compare the effects of the volatile anesthetics, isoflurane and halothane, on the cerebrovascular response to CO2 inhalation in male Sprague-Dawley rats. The effects of 0.5 and 1.5 minimum alveolar anesthetic concentrations (MAC) of halothane and isoflurane on the microcirculatory re...

journal_title：Anesthesia and analgesia

authors： Lee JG,Smith JJ,Hudetz AG,Hillard CJ,Bosnjak ZJ,Kampine JP

更新日期：1995-04-01 00:00:00

abstract：:Postoperative nausea and vomiting is common after cardiac surgery and may contribute to significant morbidity. Gastric decompression during anesthesia has been used for postoperative nausea and vomiting prophylaxis in shorter duration noncardiac surgery with conflicting results. We tested the hypothesis that gastric d...

journal_title：Anesthesia and analgesia

authors： Burlacu CL,Healy D,Buggy DJ,Twomey C,Veerasingam D,Tierney A,Moriarty DC

更新日期：2005-02-01 00:00:00

abstract：:The low solubility of sevoflurane in blood suggests that this agent should enter and leave the body more rapidly than isoflurane. However, the closeness of sevoflurane and isoflurane tissue/blood partition coefficients suggests that the rates of equilibration with and elimination from tissues should be similar. We tes...

journal_title：Anesthesia and analgesia

authors： Yasuda N,Lockhart SH,Eger EI 2nd,Weiskopf RB,Liu J,Laster M,Taheri S,Peterson NA

更新日期：1991-03-01 00:00:00