Characterization of the Rapid Drop in Pulse Oximetry Reading After Intraoperative Administration of Methylene Blue in Open Thoracoabdominal Aortic Repairs.

Abstract:

:This study evaluates the changes of oxygen saturation (SpO2) after intravenous administration of methylene blue in 103 patients undergoing open repair of thoracoabdominal aortic aneurysms. We found that SpO2 decreased by a median (interquartile range [IQR]) of 49% (37%-81%) <1 minute after methylene blue administration and recovered completely after approximately 6 minutes-median (IQR) of 270 seconds (180-510). A shorter time to nadir SpO2 was associated with a higher nadir (Spearman r [95% confidence interval {CI}], -0.32 [-0.50 to -0.13]; P = .001). Body surface area (BSA) was positively correlated with nadir SpO2 (Spearman r [95% CI], 0.36 [0.15-0.51]; P < .001).

journal_name

Anesth Analg

journal_title

Anesthesia and analgesia

authors

Rong LQ,Mauer E,Mustapich TL,White RS,Di Franco A,Girardi LN,Gaudino M,Pryor KO

doi

10.1213/ANE.0000000000004325

subject

Has Abstract

pub_date

2019-11-01 00:00:00

pages

e142-e145

issue

5

eissn

0003-2999

issn

1526-7598

journal_volume

129

pub_type

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