Venodilation contributes to propofol-mediated hypotension in humans.

abstract：BACKGROUND:Calmodulin (CaM) activation by Ca(2+), its translocation to the nucleus, and stimulation of phosphorylation of cyclic adenosine monophosphate response element-binding protein (CREB) (P-CREB) are necessary for new gene expression and have been linked to long-term potentiation, a process important in memory fo...

journal_title：Anesthesia and analgesia

authors： Zhang J,Sutachan JJ,Montoya-Gacharna J,Xu CF,Xu F,Neubert TA,Recio-Pinto E,Blanck TJ

更新日期：2009-10-01 00:00:00

abstract：:In a porcine model of uncontrolled hemorrhagic shock, we evaluated the effects of fluid resuscitation versus arginine vasopressin (AVP) combined with hypertonic-hyperoncotic hydroxyethyl starch solution (HHS) on cerebral perfusion pressure (CPP) and on cerebral metabolism using intracerebral microdialysis. Sixteen ane...

journal_title：Anesthesia and analgesia

authors： Meybohm P,Cavus E,Bein B,Steinfath M,Brand PA,Scholz J,Dörges V

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Every facility that performs cases on holidays has in some way decided on its operating room (OR) and anesthesia staffing for holidays. Previous studies have not examined how best to calculate appropriate holiday staffing. METHODS:We analyzed weekend and holiday data from a university hospital. RESULTS:The...

journal_title：Anesthesia and analgesia

authors： Dexter F,Epstein RH

更新日期：2006-12-01 00:00:00

abstract：:In this prospective randomized, double-blind study, we investigated the effect of ondansetron on the lidocaine subarachnoid block. Fifty-four male patients scheduled for transurethral surgery under subarachnoid anesthesia received oral ondansetron 4 mg the evening before surgery and 4 mg IV 15 min before subarachnoid ...

journal_title：Anesthesia and analgesia

authors： Fassoulaki A,Melemeni A,Zotou M,Sarantopoulos C

更新日期：2005-06-01 00:00:00

abstract：UNLABELLED:Nonsteroidal antiinflammatory drugs (NSAIDs) provide effective postoperative analgesia after arthroscopic knee surgery. Some investigators have suggested that the preemptive administration of NSAIDs may reduce postoperative analgesic requirements and hypersensitivity. We evaluated the analgesic effect of adm...

journal_title：Anesthesia and analgesia

authors： Reuben SS,Bhopatkar S,Maciolek H,Joshi W,Sklar J

更新日期：2002-01-01 00:00:00

abstract：:Cerebral computer tomography is a recently introduced neuroradiologic procedure involving tomographic x-rays of horizontal brain sections. Although most adults undergo the procedure without anesthesia, children and uncooperative adults must be given general anesthesia for absolute immobility. Of 84 procedures under ge...

journal_title：Anesthesia and analgesia

authors： Ferrer-Brechner T,Winter J

更新日期：1977-05-01 00:00:00

abstract：BACKGROUND:QT interval prolongation is associated with torsades des pointes (TdP), but is a poor predictor of drug torsadogenicity. Susceptibility to TdP arises from increased transmural dispersion of repolarization (TDR) across the myocardial wall, rather than QT interval prolongation per se. TDR can be measured on th...

journal_title：Anesthesia and analgesia

authors： Whyte SD,Sanatani S,Lim J,Booker PD

更新日期：2007-02-01 00:00:00

abstract：UNLABELLED:In a 28-mo period 14 multiple-casualty terror events occurred in Jerusalem, challenging the Department of Anesthesiology and Critical Care Medicine of the city's sole Level 1 trauma center. We performed a retrospective review of the response of the department to evaluate staff activities, resource use (emerg...

journal_title：Anesthesia and analgesia

authors： Shamir MY,Weiss YG,Willner D,Mintz Y,Bloom AI,Weiss Y,Sprung CL,Weissman C

更新日期：2004-06-01 00:00:00

abstract：:The anesthetic effect of lidocaine was evaluated in rats by determining the change in anesthetic requirement of cyclopropane MAC that was produced by blood concentrations of lidocaine in the clinically useful range. A linear reduction in anesthetic requirement was produced with concentrations up to 1 mug/ml. Further i...

journal_title：Anesthesia and analgesia

authors： DiFazio CA,Neiderlehner JR,Burney RG

更新日期：1976-11-01 00:00:00

abstract：:The extent of sensory and motor blockades was examined in 195 patients 5 and 20 min after four different techniques of brachial plexus block using 50 ml of 0.5% bupivacaine. The interscalene technique of Winnie (N = 50) resulted in a preferential blockade of the caudad portions of the cervical plexus and the cephalad ...

journal_title：Anesthesia and analgesia

authors： Lanz E,Theiss D,Jankovic D

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:As part of the Thai Anesthesia Incidents Study of anesthetic adverse outcomes, we evaluated the incidence and factors related to cardiac arrest during spinal anesthesia. METHODS:During a 12-mo period (March 1, 2003, to February 28, 2004), a prospective, multicenter registry of patients receiv...

journal_title：Anesthesia and analgesia

authors： Charuluxananan S,Thienthong S,Rungreungvanich M,Chanchayanon T,Chinachoti T,Kyokong O,Punjasawadwong Y

更新日期：2008-11-01 00:00:00

abstract：:The effects of volatile anesthetics on arterial mechanical properties in vivo are incompletely understood. The present investigation tested the hypothesis that isoflurane and halothane cause differential actions on the mechanical characteristics of the aorta in barbiturate-anesthetized dogs instrumented for measuremen...

journal_title：Anesthesia and analgesia

authors： Hettrick DA,Pagel PS,Warltier DC

更新日期：1996-12-01 00:00:00

abstract：:Prostaglandin E(2) receptors, subtype EP(1) (PGE(2)EP(1)) have been linked to several physiologic responses, such as fever, inflammation, and mechanical hyperalgesia. Local anesthetics modulate these responses, which may be due to direct interaction of local anesthetics with PGE(2)EP(1) receptor signaling. We sought t...

journal_title：Anesthesia and analgesia

authors： Hönemann CW,Heyse TJ,Möllhoff T,Hahnenkamp K,Berning S,Hinder F,Linck B,Schmitz W,van Aken H

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Several data suggest that both opioid and N-methyl-d-aspartate (NMDA) receptors are localized at the peripheral level, and drugs acting on these receptors may produce antinociception after topical administration; however, the antinociceptive effect of endogenous ligands at these receptors is poorly clarified...

journal_title：Anesthesia and analgesia

authors： Mecs L,Tuboly G,Nagy E,Benedek G,Horvath G

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:This study investigated the clinical performance of a model-based, patient-individualized closed-loop (CL) control system for propofol administration using the bispectral index (BIS) as a controlled variable during the induction and maintenance of anesthesia with propofol and remifentanil and studied the inf...

journal_title：Anesthesia and analgesia

authors： Neckebroek M,Boldingh JHL,De Smet T,Struys MMRF

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:In clinical anesthesia, robust surgical stress occasionally causes unintended light anesthesia during operation. To test the hypothesis that neural input condition could modify actions of general anesthetics as a result of presynaptic alteration in the central nervous system, we investigated the mechanisms b...

journal_title：Anesthesia and analgesia

authors： Hirota K,Sasaki R,Roth SH,Yamazaki M

更新日期：2010-06-01 00:00:00

abstract：UNLABELLED:Certain dietary proteins and oils are capable of decreasing chronic neuropathic pain levels in rats after partial sciatic nerve ligation injury. We tested, for the first time, the role of dietary polyunsaturated fatty acids in suppressing pain in partial sciatic nerve ligation-injured rats. Six groups of mal...

journal_title：Anesthesia and analgesia

authors： Pérez J,Ware MA,Chevalier S,Gougeon R,Shir Y

更新日期：2005-08-01 00:00:00

abstract：:After it was learned that electroanesthesia (EA) could not be produced in a Rhesus monkey which had undergone a circumferential scalp block with 0.25% lidocaine, it was postulated that EA could be produced by electrostimulation of the sensory nerves of the scalp in the rhesus. The work reported here verifies that EA c...

journal_title：Anesthesia and analgesia

authors： Kano T,Cowan GS,Smith RH

更新日期：1976-07-01 00:00:00

abstract：:Rifampin is commonly used for the treatment of tuberculosis and staphylococcal infections, as well as for prevention of infection in cardiac valve and bone surgeries. We report a case of profound hypotension after anesthesia induction with propofol in a patient who was treated with two 600 mg doses of rifampin for pro...

journal_title：Anesthesia and analgesia

authors： Mirzakhani H,Nozari A,Ehrenfeld JM,Peterfreund R,Szabo M,Walsh JL,Jiang Y,Sandberg W,Rosow C,Wang J

更新日期：2013-07-01 00:00:00

abstract：:Tramadol analgesia results from a monoaminergic effect by tramadol itself and an opioid effect of its metabolite (+)-M1 formed by O-demethylation of tramadol by CYP2D6. In this study we sought to determine the impact of (+)-M1 on the analgesic effect of tramadol evaluated by experimental pain models. The effect of an ...

journal_title：Anesthesia and analgesia

authors： Enggaard TP,Poulsen L,Arendt-Nielsen L,Brøsen K,Ossig J,Sindrup SH

更新日期：2006-01-01 00:00:00

abstract：UNLABELLED:We investigated the effects of isoflurane-induced burst suppression, monitored with electroencephalography (EEG), on cerebral blood flow velocity (CBFV), cerebral oxygen extraction (COE), and autoregulation in 16 patients undergoing cardiac surgery. The experimental procedure was performed during nonpulsatil...

journal_title：Anesthesia and analgesia

authors： Reinsfelt B,Westerlind A,Houltz E,Ederberg S,Elam M,Ricksten SE

更新日期：2003-11-01 00:00:00

abstract：:After Fontan repair in children, we performed a prospective, open-label study to evaluate the effect of amrinone on pulmonary vascular resistance (PVRI). Eight patients who underwent the Fontan repair had baseline arterial pressure, left atrial pressure, central venous pressure, and cardiac output measured postoperati...

journal_title：Anesthesia and analgesia

authors： Sorensen GK,Ramamoorthy C,Lynn AM,French J,Stevenson JG

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:The arterial pulse oximeter, which was introduced clinically in the 1970s, is a convenient, useful, and now ubiquitous anesthesia monitor. Unfortunately, although percent saturation of arterial hemoglobin is, along with cardiac output and concentration of hemoglobin, one of 3 components of oxygen delivery, i...

journal_title：Anesthesia and analgesia

authors： Thiele RH,Tucker-Schwartz JM,Lu Y,Gillies GT,Durieux ME

更新日期：2011-06-01 00:00:00

abstract：:We compared in a prospective, randomized, double-blinded study the analgesic efficacy of three drugs in 120 ASA I and II patients scheduled to undergo ambulatory hand surgery with IV regional anesthesia. At discharge, oral analgesic tablets were prescribed as follows: tramadol 100 mg every 6 h, metamizol 1 g every 6 h...

journal_title：Anesthesia and analgesia

authors： Rawal N,Allvin R,Amilon A,Ohlsson T,Hallén J

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:Midazolam is the most commonly used premedication in children. It has been shown to be more effective than parental presence or placebo in reducing anxiety and improving compliance at induction of anesthesia. Clonidine, an alpha(2) agonist, has been suggested as an alternative. Dexmedetomidine is a more alph...

journal_title：Anesthesia and analgesia

authors： Yuen VM,Hui TW,Irwin MG,Yuen MK

更新日期：2008-06-01 00:00:00

abstract：UNLABELLED:The Bispectral Index (BIS) correlates well with the level of consciousness with single anesthetic drugs. We studied the effect of the interaction of propofol with alfentanil on propofol concentration and BIS associated with 50% probability of loss of consciousness and lack of recall (Cp50 and BIS50, respecti...

journal_title：Anesthesia and analgesia

authors： Iselin-Chaves IA,Flaishon R,Sebel PS,Howell S,Gan TJ,Sigl J,Ginsberg B,Glass PS

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:Among the various factors influencing the success rate, onset time, and duration of peripheral nerve blocks, the role of local anesthetics concentration remains uncertain. In this prospective, randomized, single-blinded study, we evaluated whether varying the dilution of a fixed dose of mepivacaine solution ...

journal_title：Anesthesia and analgesia

authors： Cappelleri G,Ambrosoli AL,Turconi S,Gemma M,Ricci EB,Cornaggia G

更新日期：2014-08-01 00:00:00

abstract：UNLABELLED:Despite their contribution to overall perioperative treatment of patients, anesthesiologists often remain in anonymity. We evaluated the impact of business cards on physician recognition after general anesthesia. Using a questionnaire, 441 patients were interviewed for recall of the anesthesiologist's name, ...

journal_title：Anesthesia and analgesia

authors： Jeske HC,Lederer W,Lorenz I,Kolbitsch C,Margreiter J,Kinzl J,Benzer A

更新日期：2001-11-01 00:00:00

abstract：UNLABELLED:Several factors are responsible for hypercarbia during laparoscopic procedures. This study was undertaken because we observed a sudden increase in PaCO(2) in children with portal hypertension (PHT), which was unusual in healthy children undergoing laparoscopic procedures. Fifty-seven children underwent lapar...

journal_title：Anesthesia and analgesia

authors： Bozkurt P,Kaya G,Yeker Y,Sarimurat N,Yesildag E,Tekant G,Emir H,Senyuz OF

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:The goal of this study was to determine a set of timing, shape, and statistical features available through noninvasive monitoring of maternal electrocardiogram and photoplethysmography that identifies preeclamptic patients. METHODS:Pregnant women admitted to Labor and Delivery were monitored with pulse oxim...

journal_title：Anesthesia and analgesia

authors： Euliano TY,Michalopoulos K,Singh S,Gregg AR,Del Rio M,Vasilopoulos T,Johnson AM,Onkala A,Darmanjian S,Euliano NR,Ho M

更新日期：2018-03-01 00:00:00