The analgesic effect of tramadol after intravenous injection in healthy volunteers in relation to CYP2D6.

abstract：UNLABELLED:We evaluated the effect of 1, 20, and 40 mL of epidural saline flush on recovery from lidocaine epidural anesthesia. Eight volunteers were studied for three study periods, each separated by 72 h. The volume of saline was randomized, and a new catheter was inserted for each study period. A standardized dose o...

journal_title：Anesthesia and analgesia

authors： Chan VW,Nazarnia S,Kaszas Z,Perlas A

更新日期：1999-10-01 00:00:00

abstract：:Heart transplant recipients are susceptible to a number of complications in the immediate postoperative period. Despite advances in surgical techniques, mechanical circulatory support (MCS), and immunosuppression, evidence supporting optimal management strategies of the critically ill transplant patient is lacking on ...

journal_title：Anesthesia and analgesia

authors： Shen T,Huh MH,Czer LS,Vaidya A,Esmailian F,Kobashigawa JA,Nurok M

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:The ability to identify the correct vertebral level through examination is an important skill for clinicians who are performing nerve blocks without fluoroscopy. The conventional palpation method, which identifies the most prominent cervical spinous process as the seventh cervical (C7) spinous process is unr...

journal_title：Anesthesia and analgesia

authors： Shin S,Yoon DM,Yoon KB

更新日期：2011-05-01 00:00:00

abstract：:To evaluate the effects of succinylcholine on cardiac arrhythmias and serum levels of potassium and catecholamines, dogs with hypoxia alone and with hypoxia and hypercarbia were studied during anesthesia with halothane or enflurane. After the injection of succinylcholine (0.3 mg/kg), cardiac arrhythmias occurred in al...

journal_title：Anesthesia and analgesia

authors： Leiman BC,Katz J,Butler BD

更新日期：1987-12-01 00:00:00

abstract：:Waste anesthetic gas scavenging technology has not changed appreciably in the past 30 years. Open reservoir systems entrain high volumes of room air and dilute waste gases before emission into the atmosphere. This process requires a large vacuum pump, which is both costly to install and, although efficient, operates c...

journal_title：Anesthesia and analgesia

authors： Barwise JA,Lancaster LJ,Michaels D,Pope JE,Berry JM

更新日期：2011-11-01 00:00:00

abstract：UNLABELLED:We evaluated, by using a before-and-after study, the influence of leukoreduction by filtration on postoperative infections and adverse outcomes in patients undergoing elective major aortic surgery. From January 1995 to October 2000, all patients who underwent elective abdominal aortic surgery were included i...

journal_title：Anesthesia and analgesia

authors： Baron JF,Gourdin M,Bertrand M,Mercadier A,Delort J,Kieffer E,Coriat P

更新日期：2002-03-01 00:00:00

abstract：:A double-blind study comparing four narcotic analgesics of different potencies, meperidine, morphine, fentanyl, and sufentanil, was performed on consenting patients undergoing general or orthopedic surgery under balanced anesthesia. Blood pressure, measured through an indwelling arterial catheter, was recorded continu...

journal_title：Anesthesia and analgesia

authors： Flacke JW,Bloor BC,Kripke BJ,Flacke WE,Warneck CM,Van Etten AP,Wong DH,Katz RL

更新日期：1985-09-01 00:00:00

abstract：BACKGROUND:In patients undergoing total knee arthroplasty under spinal anesthesia, we compared the postoperative analgesic effect of intraoperative sedation with dexmedetomidine versus propofol. We hypothesized that sedation with dexmedetomidine would result in lower postoperative opioid analgesic consumption than with...

journal_title：Anesthesia and analgesia

authors： Shin HJ,Do SH,Lee JS,Kim TK,Na HS

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Rapid establishment of a patent airway in ill or injured patients is a priority for prehospital rescue personnel. Out-of-hospital tracheal intubation can be challenging. Unrecognized esophageal intubation is a clinical disaster. METHODS:We performed an observational, prospective study of consecutive patient...

journal_title：Anesthesia and analgesia

authors： Timmermann A,Russo SG,Eich C,Roessler M,Braun U,Rosenblatt WH,Quintel M

更新日期：2007-03-01 00:00:00

abstract：UNLABELLED:The most effective group of drugs for the treatment of severe pain is opioid analgesics. Their use, however, is limited by decreased effects in neuropathic and chronic pain as a result of increased pain and development of tolerance. Gabapentin (GBP) is effective in both experimental models of chronic pain an...

journal_title：Anesthesia and analgesia

authors： Eckhardt K,Ammon S,Hofmann U,Riebe A,Gugeler N,Mikus G

更新日期：2000-07-01 00:00:00

abstract：:The effects of ropivacaine, a new amide local anesthetic, on uterine blood flow and fetal well-being were compared with those of bupivacaine in 10 chronically instrumented pregnant ewes. In random sequence, animals received two intravenous infusions of each drug. The low infusion rate regimens were chosen to result in...

journal_title：Anesthesia and analgesia

authors： Santos AC,Arthur GR,Roberts DJ,Wlody D,Pedersen H,Morishima HO,Finster M,Covino BG

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Volatile inhaled anesthetics exert a differential protective effect against bronchospasm development after cholinergic stimulation. However, their ability to inhibit the adverse respiratory consequences of an anaphylactic reaction after exposure to an allergen has not been characterized. We therefore compare...

journal_title：Anesthesia and analgesia

authors： Lele E,Petak F,Carnesecchi S,Virag K,Argiroffo CB,Habre W

更新日期：2013-06-01 00:00:00

abstract：:Tissue Doppler Imaging (TDI) provides information on systolic function through its systolic mitral annulus velocity wave (Sm), reflecting the peak velocity of shortening of the myocardial fibers oriented in the longitudinal direction. In this study, we evaluated the effect of load changes on Sm. Forty-two cardiac surg...

journal_title：Anesthesia and analgesia

authors： Amà R,Segers P,Roosens C,Claessens T,Verdonck P,Poelaert J

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Opioids are frequently used in chronic pain management but are associated with significant morbidity and mortality in some patient populations. An important avenue for identifying complications-including serious or rare complications-is the study of closed malpractice claims. The present study is intended to...

journal_title：Anesthesia and analgesia

authors： Abrecht CR,Brovman EY,Greenberg P,Song E,Rathmell JP,Urman RD

更新日期：2017-11-01 00:00:00

abstract：:An obese woman with periodic sommolence developed postoperative ventilatory problems following an uncomplicated cholecystectomy. A severe myopathic process involving the respiratory muscles was found at necropsy. A brother, who died a week later, had myotonic dystrophy. ...

journal_title：Anesthesia and analgesia

authors： Tsueda K,Shibutani K,Lefkowitz M

更新日期：1975-07-01 00:00:00

abstract：:Rapid sequence induction and intubation (RSII) and awake tracheal intubation are commonly used anesthetic techniques in patients at risk of pulmonary aspiration of gastric or esophageal contents. Some of these patients may have a gastric tube (GT) placed preoperatively. Currently, there are no guidelines regarding whi...

journal_title：Anesthesia and analgesia

authors： Salem MR,Khorasani A,Saatee S,Crystal GJ,El-Orbany M

更新日期：2014-03-01 00:00:00

abstract：:The aim of this study was to correlate pupillary diameter with respiratory depression for 20 hr after epidural administration of morphine or buprenorphine. Pupillary diameter and the ventilatory sensitivity to CO2 were measured in six healthy volunteers at various times (0, 0.5, 1, 2, 3, 4, 6, 8, 10, 12, and 20 hr) in...

journal_title：Anesthesia and analgesia

authors： Ravnborg M,Jensen FM,Jensen NH,Holk IK

更新日期：1987-09-01 00:00:00

abstract：UNLABELLED:Animal studies have suggested that the temporal summation of nociceptive inputs might play a significant role in the development of central sensitization (i.e., hyperexcitability of central nociceptive neurons) and hyperalgesia via the activation of N-methyl-D-aspartate receptors. To further analyze these pr...

journal_title：Anesthesia and analgesia

authors： Guirimand F,Dupont X,Brasseur L,Chauvin M,Bouhassira D

更新日期：2000-02-01 00:00:00

abstract：UNLABELLED:To determine whether a weight-related dose had advantages over a fixed, large-dose regimen, we measured plasma concentrations of aprotinin by using an enzyme-linked immunosorbent assay method at set time points in 30 patients having heart surgery with cardiopulmonary bypass. A weight-related dose comprising ...

journal_title：Anesthesia and analgesia

authors： Royston D,Cardigan R,Gippner-Steppert C,Jochum M

更新日期：2001-04-01 00:00:00

abstract：:Sensory level of anesthesia following the injection of 20 ml of 1.5% lidocaine with epinephrine (1:200,000) in 238 adult males averaged T7.7, T5.6, and T5.1 at 10, 20, and 30 minutes, respectively. Patient age had no significant effect on local anesthetic requirements per spinal segment per unit height until age 40 ye...

journal_title：Anesthesia and analgesia

authors： Park WY,Massengale M,Kim SI,Poon KC,Macnamara TE

更新日期：1980-10-01 00:00:00

abstract：UNLABELLED:We describe the development and evaluation of a simple slide rule that enables the bedside determination of the infusion rate for a particular target plasma concentration of propofol. The infusion rate to reach this target concentration at time (t) is the product of the target concentration, body weight, and...

journal_title：Anesthesia and analgesia

authors： Bruhn J,Bouillon TW,Röpcke H,Hoeft A

更新日期：2003-01-01 00:00:00

abstract：:We compared the effect of the lithotomy position on the systolic blood pressure (SBP) with the horizontal position after spinal block. The lithotomy position was performed 5 min after spinal block. The change in SBP was expressed as percent of depression from the baseline value. The SBP increased by the lithotomy posi...

journal_title：Anesthesia and analgesia

authors： Miyabe M,Sonoda H,Namiki A

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND:Pro- and anti-inflammatory cytokines (adipokines) associated with adipose tissue can modulate inflammatory processes and lead to systemic inflammatory conditions such as metabolic syndrome. In the present pilot study, we investigated 3 major adipokines (leptin, adiponectin, and resistin) and 2 nonspecific pr...

journal_title：Anesthesia and analgesia

authors： Hozumi J,Sumitani M,Nishizawa D,Nagashima M,Ikeda K,Abe H,Kato R,Kusakabe Y,Yamada Y,Japanese Translational Research-Cancer Pain Research Group.

更新日期：2019-03-01 00:00:00

abstract：:Combinations of benzodiazepines (midazolam and diazepam) with barbiturates (pentobarbital and phenobarbital) exhibit synergistic (supra-additive) hypnotic interactions in rats. Because both benzodiazepines and barbiturates interact with the gamma-aminobutyric acidA (GABAA) receptor complex, we have tested the hypothes...

journal_title：Anesthesia and analgesia

authors： DeLorey TM,Kissin I,Brown P,Brown GB

更新日期：1993-09-01 00:00:00

abstract：:The effects of nitrous oxide-oxygen plus small doses of fentanyl with (N = 7) and without (N = 15) naloxone and the effects of nitrous oxide-oxygen plus halothane (N = 13) on plasma concentration of arginine vasopressin (AVP) and cortisol were studied in normal patients before and during gynecologic laparotomies. Pati...

journal_title：Anesthesia and analgesia

authors： Lehtinen AM,Fyhrquist F,Kivalo I

更新日期：1984-01-01 00:00:00

abstract：INTRODUCTION:The mechanisms by which mechanical ventilation (MV) can injure remote organs, such as the kidney, remain poorly understood. We hypothesized that upregulation of systemic inflammation, as reflected by plasma interleukin-6 (IL-6) levels, in response to a lung-injurious ventilatory strategy, ultimately result...

journal_title：Anesthesia and analgesia

authors： Kuiper JW,Versteilen AM,Niessen HW,Vaschetto RR,Sipkema P,Heijnen CJ,Groeneveld AB,Plötz FB

更新日期：2008-10-01 00:00:00

abstract：UNLABELLED:To evaluate the influence of needle type on the lateral distribution of 0.5% hyperbaric bupivacaine, 30 patients undergoing lower limb surgery were placed in the lateral position with the side to be operated on dependent and underwent dural puncture by either a 25-gauge Whitacre (n = 15) or a 25-gauge Quinck...

journal_title：Anesthesia and analgesia

authors： Casati A,Fanelli G,Cappelleri G,Aldegheri G,Leoni A,Casaletti E,Torri G

更新日期：1998-08-01 00:00:00

abstract：:Isoproterenol 5 micrograms may be an effective marker of accidental intravascular injection in women in labor; however, before isoproterenol can be incorporated in routinely used epidural test doses, the safety and usefulness should be determined in an animal model. This study was designed to examine the hemodynamic e...

journal_title：Anesthesia and analgesia

authors： Marcus MA,Vertommen JD,Van Aken H,Wouters PF

更新日期：1996-05-01 00:00:00

abstract：UNLABELLED:The site for needle insertion in femoral nerve block varies significantly among various descriptions of the technique. To determine the site with the highest likelihood of needle-femoral nerve contact, femoral nerve block was simulated in a human cadaver model (17 femoral triangles from 9 adult cadavers). Fo...

journal_title：Anesthesia and analgesia

authors： Vloka JD,Hadzić A,Drobnik L,Ernest A,Reiss W,Thys DM

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:The blood/gas partition coefficient of a certain volatile anesthetic is of clinical importance because it determines its velocity of uptake into and elimination from the body of a patient and thus its pharmacokinetic behavior. To date, the blood/gas partition coefficients of isoflurane, sevoflurane, and desf...

journal_title：Anesthesia and analgesia

authors： Esper T,Wehner M,Meinecke CD,Rueffert H

更新日期：2015-01-01 00:00:00