Does hyperventilation improve operating condition during supratentorial craniotomy? A multicenter randomized crossover trial.

abstract：BACKGROUND:Recombinant activated factor VII (rFVIIa) is increasingly used for treating refractory bleeding after cardiac surgery. However, hemostasis also depends on coagulation factors, including fibrinogen, which stabilizes platelet plugs at sites of vascular injury. We compared the hemostatic effects of rFVIIa, fibr...

journal_title：Anesthesia and analgesia

authors： Tanaka KA,Taketomi T,Szlam F,Calatzis A,Levy JH

更新日期：2008-03-01 00:00:00

abstract：UNLABELLED:Whether tracheal intubation is more difficult in obese patients is debatable. We compared the incidence of difficult tracheal intubation in obese and lean patients by using a recently validated objective scale, the intubation difficulty scale (IDS). We studied 134 lean (body mass index, <30 kg/m2) and 129 ob...

journal_title：Anesthesia and analgesia

authors： Juvin P,Lavaut E,Dupont H,Lefevre P,Demetriou M,Dumoulin JL,Desmonts JM

更新日期：2003-08-01 00:00:00

abstract：:High blood concentrations of local anesthetics are cardiotoxic. The aim of this study was to compare the effects of lidocaine and bupivacaine on the intrinsic pacemaker activity of in vitro sinoatrial nodal cells of the adult and neonatal guinea pig in the presence and absence of hypoxia and acidosis. Fifteen pairs of...

journal_title：Anesthesia and analgesia

authors： Bosnjak ZJ,Stowe DF,Kampine JP

更新日期：1986-09-01 00:00:00

abstract：:A number of important clinical trials focusing on critically ill patients have been completed in the last few years. These trials have been among the first critical care clinical trials to demonstrate mortality reduction in the critically ill. As in any adaptation of evidence-based medicine, it is essential to closely...

journal_title：Anesthesia and analgesia

authors： Gropper MA

更新日期：2004-08-01 00:00:00

abstract：:The effect of ketamine on intraocular pressure (IOP) was studied in 10 children. Control IOP values were determined prior to induction of anesthesia, following premedication with atropine alone or in combination with pentobarbital and meperidine. After the IM injection of 8 mg/kg of ketamine, the IOP was determined at...

journal_title：Anesthesia and analgesia

authors： Ausinsch B,Rayburn RL,Munson ES,Levy NS

更新日期：1976-11-01 00:00:00

abstract：:Different additives have been used to prolong regional blockade. We designed a prospective, randomized, double-blind study to evaluate the effect of dexamethasone added to lidocaine on the onset and duration of axillary brachial plexus block. Sixty patients scheduled for elective hand and forearm surgery under axillar...

journal_title：Anesthesia and analgesia

authors： Movafegh A,Razazian M,Hajimaohamadi F,Meysamie A

更新日期：2006-01-01 00:00:00

abstract：UNLABELLED:We sought to determine minimum alveolar anesthetic concentrations for skin incision (MAC) and for tracheal extubation (MAC(Ex)) for sevoflurane and its associated awakening time and respiratory complications during emergence from sevoflurane anesthesia in children. We studied 40 (20 in each group) unpremedic...

journal_title：Anesthesia and analgesia

authors： Inomata S,Suwa T,Toyooka H,Suto Y

更新日期：1998-12-01 00:00:00

abstract：:Tramadol analgesia results from a monoaminergic effect by tramadol itself and an opioid effect of its metabolite (+)-M1 formed by O-demethylation of tramadol by CYP2D6. In this study we sought to determine the impact of (+)-M1 on the analgesic effect of tramadol evaluated by experimental pain models. The effect of an ...

journal_title：Anesthesia and analgesia

authors： Enggaard TP,Poulsen L,Arendt-Nielsen L,Brøsen K,Ossig J,Sindrup SH

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Aspirin-resistant platelet activation in whole blood is attributable to a transcellular pathway not detected by isolated platelet aggregometry. Aspirin resistance as defined by urinary thromboxane levels is associated with increased risk for myocardial infarction or cardiac death. Whole blood point-of-care a...

journal_title：Anesthesia and analgesia

authors： Carroll RC,Craft RM,Snider CC,Aligeti VR,Wortham DC

更新日期：2013-02-01 00:00:00

abstract：:Ten volunteers were studied during six stages of propofol sedation, namely awake (no propofol), light sedation (small dose of propofol), deep sedation (large dose), deep sedation with stimulation of the ulnar nerve, then light sedation again (small dose), and awake (recovery). Light and deep sedation were defined in t...

journal_title：Anesthesia and analgesia

authors： Andrade J,Sapsford DJ,Jeevaratnum D,Pickworth AJ,Jones JG

更新日期：1996-12-01 00:00:00

abstract：:A series of 50 combat-injured patients given crash intubation for rapid induction of anesthesia is presented. The technic consisted of injection of 3 mg of d-tubocurarine and 0.4 mg of atropine IV, preoxygenation by face mask for 3 minutes, and then injection of sodium thiopental or ketamine, followed immediately by 6...

journal_title：Anesthesia and analgesia

authors： Cromartie RS 3rd

更新日期：1976-01-01 00:00:00

abstract：UNLABELLED:Impaired in vivo immunity is often observed after major surgery and is multifactorial. We conducted a randomized clinical study to determine the independent effects of general anesthesia (GA) and of lumbar epidural anesthesia (LEA) on human immune function in the absence of surgical trauma. Nineteen healthy ...

journal_title：Anesthesia and analgesia

authors： Procopio MA,Rassias AJ,DeLeo JA,Pahl J,Hildebrandt L,Yeager MP

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:Many new mechanical ventilation modes are proposed without any clinical evaluation. "Dual-controlled" modes, such as AutoFlow™, are supposed to improve patient- ventilator interfacing and could lead to fewer alarms. We performed a long-term clinical evaluation of the efficacy and safety of AutoFlow during as...

journal_title：Anesthesia and analgesia

authors： Lasocki S,Labat F,Plantefeve G,Desmard M,Mentec H

更新日期：2010-10-01 00:00:00

abstract：:In view of the overall experience regarding regional anesthetic techniques to control postoperative pain in infants and children, it is feasible that a similar efficacy and safety profile can be obtained when using such techniques after major orthopedic procedures such as anterior or posterior spinal fusion. I reviewe...

journal_title：Anesthesia and analgesia

authors： Tobias JD

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:Postoperative sore throat (POST) is a common complication after endotracheal intubation. We compared the effectiveness on POST of spraying the endotracheal tube (ETT) cuff with benzydamine hydrochloride, 10% lidocaine, and 2% lidocaine. METHODS:Three hundred seventy-two patients were randomly allocated into...

journal_title：Anesthesia and analgesia

authors： Hung NK,Wu CT,Chan SM,Lu CH,Huang YS,Yeh CC,Lee MS,Cherng CH

更新日期：2010-10-01 00:00:00

abstract：:We investigated the efficacy of granisetron and dolasetron in preventing postoperative nausea and vomiting. Because the metabolism of the various antiemetic 5-hydroxytryptamine type 3 (5-HT3) antagonists involves different isoforms of the hepatic cytochrome P450 system, we examined the relationship between the clinica...

journal_title：Anesthesia and analgesia

authors： Janicki PK,Schuler HG,Jarzembowski TM,Rossi M 2nd

更新日期：2006-04-01 00:00:00

abstract：:In a porcine model of uncontrolled hemorrhagic shock, we evaluated the effects of fluid resuscitation versus arginine vasopressin (AVP) combined with hypertonic-hyperoncotic hydroxyethyl starch solution (HHS) on cerebral perfusion pressure (CPP) and on cerebral metabolism using intracerebral microdialysis. Sixteen ane...

journal_title：Anesthesia and analgesia

authors： Meybohm P,Cavus E,Bein B,Steinfath M,Brand PA,Scholz J,Dörges V

更新日期：2006-10-01 00:00:00

abstract：UNLABELLED:We compared the laryngeal mask airway ProSeal (PLMA) and the laryngeal tube airway (LTA), two new extraglottic airway devices, with respect to: 1) insertion success rates and times, 2) efficacy of seal, 3) ventilatory variables during pressure-controlled ventilation, 4) tidal volume in different head/neck po...

journal_title：Anesthesia and analgesia

authors： Brimacombe J,Keller C,Brimacombe L

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Performing key actions efficiently during crises can determine clinical outcomes, yet even expert clinicians omit key actions. Simulation-based studies of crises show that correct performance of key actions dramatically increases when emergency manuals (EMs) are used. Despite widespread dissemination of EMs,...

journal_title：Anesthesia and analgesia

authors： Goldhaber-Fiebert SN,Bereknyei Merrell S,Agarwala AV,De La Cruz MM,Cooper JB,Howard SK,Asch SM,Gaba DM

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:While transfusion-related acute lung injury (TRALI) remains the primary cause of transfusion-related fatalities (37%), recent reports estimate the incidence of TRALI at 0.008% per unit of plasma transfused and 0.004% per all products transfused. Because blood banks have moved toward male-predominant plasma, ...

journal_title：Anesthesia and analgesia

authors： Meyer DE,Reynolds JW,Hobbs R,Bai Y,Hartwell B,Pommerening MJ,Fox EE,Wade CE,Holcomb JB,Cotton BA

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Every facility that performs cases on holidays has in some way decided on its operating room (OR) and anesthesia staffing for holidays. Previous studies have not examined how best to calculate appropriate holiday staffing. METHODS:We analyzed weekend and holiday data from a university hospital. RESULTS:The...

journal_title：Anesthesia and analgesia

authors： Dexter F,Epstein RH

更新日期：2006-12-01 00:00:00

abstract：UNLABELLED:The effect of opioid administration on the bispectral index (BIS) during general anesthesia is controversial. Several investigators have reported BIS to be insensitive to opioid addition, whereas others have found a hypnotic response. We designed this study to examine the effect of remifentanil on BIS during...

journal_title：Anesthesia and analgesia

authors： Koitabashi T,Johansen JW,Sebel PS

更新日期：2002-06-01 00:00:00

abstract：:Epidural anesthesia may be performed as a single injection or by staged doses. Thirty patients undergoing primary total hip replacement were randomly assigned to have epidural anesthesia using a single injection or a staged technique with 25 mL of 0.75% bupivacaine. Arterial plasma bupivacaine concentrations were sign...

journal_title：Anesthesia and analgesia

authors： Sharrock NE,Mineo R,Stanton J,Ennis WJ 3rd,Urmey WF,Arthur GR

更新日期：1994-08-01 00:00:00

abstract：:Ocular microtremor (OMT) is a fine physiologic tremor of the eye related to neuronal activity in the reticular formation of the brainstem. The frequency of OMT is suppressed by propofol and sevoflurane and predicts the response to command at emergence from anesthesia. Previous studies have relied on post hoc computer ...

journal_title：Anesthesia and analgesia

authors： Heaney M,Kevin LG,Manara AR,Clayton TJ,Timmons SD,Angel JJ,Smith KR,Ibata B,Bolger C,Cunningham AJ

更新日期：2004-09-01 00:00:00

abstract：:Propofol is associated with a low incidence of postoperative nausea and vomiting. In a prospective, randomized, double-blind, placebo-controlled study, we investigated the possible direct antiemetic properties of a subhypnotic dose of propofol. Fifty-two ASA physical status I or II patients, aged 15-60 yr with nausea ...

journal_title：Anesthesia and analgesia

authors： Borgeat A,Wilder-Smith OH,Saiah M,Rifat K

更新日期：1992-04-01 00:00:00

abstract：UNLABELLED:We studied the effect of fluvoxamine and erythromycin on the pharmacokinetics of ropivacaine in a double-blinded, randomized, four-way cross-over study. Eight healthy volunteers ingested daily 1500 mg erythromycin for 6 days, 100 mg fluvoxamine for 5 days (Days 2-6), both erythromycin and fluvoxamine, or pla...

journal_title：Anesthesia and analgesia

authors： Jokinen MJ,Ahonen J,Neuvonen PJ,Olkkola KT

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Transcutaneous vagus nerve stimulation (TVNS) is a promising treatment for acute and chronic pain. However, experimental studies yielded controversial results. We examined if TVNS reduces the perceived intensity of repetitive painful heat stimulation and temporal summation of pain (TSP) in healthy volunteers...

journal_title：Anesthesia and analgesia

authors： Janner H,Klausenitz C,Gürtler N,Hahnenkamp K,Usichenko TI

更新日期：2018-06-01 00:00:00

abstract：:Inferential statistics relies heavily on the central limit theorem and the related law of large numbers. According to the central limit theorem, regardless of the distribution of the source population, a sample estimate of that population will have a normal distribution, but only if the sample is large enough. The rel...

journal_title：Anesthesia and analgesia

authors： Mascha EJ,Vetter TR

更新日期：2018-02-01 00:00:00

abstract：UNLABELLED:We describe the development and evaluation of a simple slide rule that enables the bedside determination of the infusion rate for a particular target plasma concentration of propofol. The infusion rate to reach this target concentration at time (t) is the product of the target concentration, body weight, and...

journal_title：Anesthesia and analgesia

authors： Bruhn J,Bouillon TW,Röpcke H,Hoeft A

更新日期：2003-01-01 00:00:00

abstract：:The effects of volatile anesthetics on arterial mechanical properties in vivo are incompletely understood. The present investigation tested the hypothesis that isoflurane and halothane cause differential actions on the mechanical characteristics of the aorta in barbiturate-anesthetized dogs instrumented for measuremen...

journal_title：Anesthesia and analgesia

authors： Hettrick DA,Pagel PS,Warltier DC

更新日期：1996-12-01 00:00:00